Reaction: 12-Hydroxynevirapine to 1 product

Reaction
12-Hydroxynevirapine
DBMET00074
4-carboxynevirapine
DBMET00727
Reaction type
Not Available
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Riska P, Lamson M, MacGregor T, Sabo J, Hattox S, Pav J, Keirns J: Disposition and biotransformation of the antiretroviral drug nevirapine in humans. Drug Metab Dispos. 1999 Aug;27(8):895-901. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Aldehyde dehydrogenase, mitochondrialNot AvailableNot Availableconfirmed