Reaction: 10,11-Epoxycarbamazepine to 1 product

Reaction
10,11-Epoxycarbamazepine
DBMET00291
10,11-Dihydroxycarbamazepine
DBMET00806
Reaction type
Not Available
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
inactive
References
  1. Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE: Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96. [Article]
  2. Makar AB, McMartin KE, Palese M, Tephly TR: Formate assay in body fluids: application in methanol poisoning. Biochem Med. 1975 Jun;13(2):117-26. [Article]
  3. Kanehisa M, Goto S, Kawashima S, Okuno Y, Hattori M: The KEGG resource for deciphering the genome. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D277-80. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Epoxide hydrolase 1Not AvailableNot Availableconfirmed