Reaction: Acetylsalicylic acid to 2 products

Reaction
Acetylsalicylic acid
DB00945
Phenolic glucuronide
DBMET02417
Salicylic acid acyl glucuronide
DBMET02418
Reaction type
glucuronidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Postula M, Janicki PK, Rosiak M, Kaplon-Cieslicka A, Kondracka A, Trzepla E, Filipiak KJ, Kosior DA, Czlonkowski A, Opolski G: Effect of common single-nucleotide polymorphisms in acetylsalicylic acid metabolic pathway genes on platelet reactivity in patients with diabetes. Med Sci Monit. 2013 May 27;19:394-408. doi: 10.12659/MSM.883922. [Article]
  2. Durlaza FDA label [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 1-6Not AvailableNot Availableimplied