Reaction: Hydrocortisone to 1 product

Reaction
Hydrocortisone
DB00741
6-beta-hydrocortisol
DBMET00372
Reaction type
6-beta-hydroxylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Abel SM, Back DJ: Cortisol metabolism in vitro--III. Inhibition of microsomal 6 beta-hydroxylase and cytosolic 4-ene-reductase. J Steroid Biochem Mol Biol. 1993 Dec;46(6):827-32. doi: 10.1016/0960-0760(93)90325-q. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A SubfamilyNot AvailableNot Availableimplied