Reaction: Oxcarbazepine to 1 product
- Reaction
- Reaction type
- reduction
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- active
- References
- Malatkova P, Havlikova L, Wsol V: The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7. doi: 10.1016/j.cbi.2014.07.005. Epub 2014 Jul 22. [Article]
- Schutz H, Feldmann KF, Faigle JW, Kriemler HP, Winkler T: The metabolism of 14C-oxcarbazepine in man. Xenobiotica. 1986 Aug;16(8):769-78. doi: 10.3109/00498258609043567. [Article]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Aldo-keto reductase family 1 member C1 Not Available Not Available confirmed Aldo-keto reductase family 1 member C2 Not Available Not Available confirmed Aldo-keto reductase family 1 member C3 Not Available Not Available confirmed Aldo-keto reductase family 1 member C4 Not Available Not Available confirmed Carbonyl reductase [NADPH] 1 Not Available Not Available confirmed Carbonyl reductase [NADPH] 3 Not Available Not Available confirmed
