Reaction: Hydrocortisone to 1 product

Reaction
Hydrocortisone
DB00741
5-alpha Tetrahydrocortisol
DBMET02901
Reaction type
reduction
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Finken MJ, Andrews RC, Andrew R, Walker BR: Cortisol metabolism in healthy young adults: sexual dimorphism in activities of A-ring reductases, but not 11beta-hydroxysteroid dehydrogenases. J Clin Endocrinol Metab. 1999 Sep;84(9):3316-21. doi: 10.1210/jcem.84.9.6009. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
3-oxo-5-alpha-steroid 4-dehydrogenase 2Not AvailableNot Availableconfirmed