Reaction: L-Glutamine to 1 product

Reaction
L-Glutamine
DB00130
Glutamate
DBMET02102
Reaction type
Not Available
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Cruzat V, Macedo Rogero M, Noel Keane K, Curi R, Newsholme P: Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients. 2018 Oct 23;10(11). pii: nu10111564. doi: 10.3390/nu10111564. [Article]
  2. Xiao D, Zeng L, Yao K, Kong X, Wu G, Yin Y: The glutamine-alpha-ketoglutarate (AKG) metabolism and its nutritional implications. Amino Acids. 2016 Sep;48(9):2067-80. doi: 10.1007/s00726-016-2254-8. Epub 2016 May 9. [Article]
  3. Hu CA, Khalil S, Zhaorigetu S, Liu Z, Tyler M, Wan G, Valle D: Human Delta1-pyrroline-5-carboxylate synthase: function and regulation. Amino Acids. 2008 Nov;35(4):665-72. doi: 10.1007/s00726-008-0075-0. Epub 2008 Apr 10. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Glutamine synthetaseNot AvailableNot Availableconfirmed
Glutaminase liver isoform, mitochondrialNot AvailableNot Availableimplied
Glutaminase kidney isoform, mitochondrialNot AvailableNot Availableimplied