Reaction: Abrocitinib to 1 product
- Reaction
- Reaction type
- oxidation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- inactive
- References
- Tripathy S, Wentzel D, Wan XK, Kavetska O: Validation of enantioseparation and quantitation of an active metabolite of abrocitinib in human plasma. Bioanalysis. 2021 Oct;13(19):1477-1486. doi: 10.4155/bio-2021-0128. Epub 2021 Oct 4. [Article]
- FDA Approved Drug Products: CIBINQO (abrocitinib) tablets, for oral use [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 2C19 Not Available Not Available implied Cytochrome P450 2C9 Not Available Not Available implied Cytochrome P450 3A4 Not Available Not Available implied Cytochrome P450 2B6 Not Available Not Available implied