Reaction: Abiraterone to 1 product
- Reaction
- Reaction type
- sulfation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- inactive
- References
- Acharya M, Gonzalez M, Mannens G, De Vries R, Lopez C, Griffin T, Tran N: A phase I, open-label, single-dose, mass balance study of 14C-labeled abiraterone acetate in healthy male subjects. Xenobiotica. 2013 Apr;43(4):379-89. doi: 10.3109/00498254.2012.721022. Epub 2012 Sep 28. [Article]
- FDA Approved Drug Products: YONSA (abiraterone acetate) tablets for oral use (March 2022) [Link]
- FDA Approved Drug Products: ZYTIGA (abiraterone acetate) tablets for oral use (August 2021) [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 3A4 Not Available Not Available implied Bile salt sulfotransferase Not Available Not Available implied
