Aceclofenac in the management of inflammatory pain.
Article Details
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Legrand E
Aceclofenac in the management of inflammatory pain.
Expert Opin Pharmacother. 2004 Jun;5(6):1347-57.
- PubMed ID
- 15163279 [ View in PubMed]
- Abstract
Aceclofenac (Almirall Prodesfarma SA) is an oral NSAID that is effective in the treatment of painful inflammatory diseases and has been used to treat > 75 million patients worldwide. It has proved as effective as diclofenac, naproxen and piroxicam in patients with osteoarthritis, diclofenac, ketorolac, tenoxicam and indomethacin in patients with rheumatoid arthritis and tenoxicam, naproxen and indomethacin in patients with ankylosing spondylitis. It also provides effective analgesia in other indications, such as dental or gynaecological pain, lower back pain and ear, nose and throat indications. Aceclofenac appears to be particularly well-tolerated amongst the NSAIDs, with a lower incidence of gastrointestinal adverse effects. This good tolerability profile results in a reduced withdrawal rate and hence greater compliance with treatment.
DrugBank Data that Cites this Article
- Drugs
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Aceclofenac Prostaglandin G/H synthase 1 Protein Humans YesInhibitorDetails Aceclofenac Prostaglandin G/H synthase 2 Protein Humans YesInhibitorDetails - Drug Reactions
Reaction Details