Progesterone binding to the tryptophan residues of human alpha1-acid glycoprotein.

Article Details

Citation

Copy to clipboard

Albani JR

Progesterone binding to the tryptophan residues of human alpha1-acid glycoprotein.

Carbohydr Res. 2006 Nov 6;341(15):2557-64. Epub 2006 Aug 8.

PubMed ID

16901474 [ View in PubMed

]

Abstract

Binding studies between progesterone and alpha1-acid glycoprotein allowed us to demonstrate that the binding site of progesterone contains one hydrophobic tryptophan residue and that the structure of the protein is not altered upon binding. The data obtained at saturated concentrations of progesterone clearly reveal the type of interaction at physiological levels.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Progesterone	Alpha-1-acid glycoprotein 1	Protein	Humans	Unknown	Binder	Details