Proteolysis of fibrinogen in healthy volunteers following major and minor vivo plasminogen activation.
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Prowse CV, Dawes J, Lane DA, Ireland H, Knight I
Proteolysis of fibrinogen in healthy volunteers following major and minor vivo plasminogen activation.
Thromb Res. 1982 Jul 1;27(1):91-7. doi: 10.1016/0049-3848(82)90282-1.
- PubMed ID
- 6750837 [ View in PubMed]
- Abstract
Changes in immunoreactive fibrinopeptide A, fragment B beta 1-42 and fragment E were followed after major and minor in vivo plasminogen activation, after infusion of streptokinase and acylated streptokinase-plasminogen complex respectively, in healthy male volunteers. Major activation resulted in a dramatic rise in all three peptides, fragment E persisting in the circulation longest. Fragment B beta 1-42 was also markedly increased after minor systemic plasminogen activation despite apparently adequate levels of immediate antiplasmin.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Anistreplase Fibrinogen alpha chain Protein Humans YesNot Available Details