Exopenicillinase synthesis in Staphylococcus aureus.

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Coles NW, Gross R

Exopenicillinase synthesis in Staphylococcus aureus.

J Bacteriol. 1969 May;98(2):659-61.

PubMed ID
5784217 [ View in PubMed
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Abstract

In Staphylococcus aureus, penicillinase remaining cell-bound (60 to 75% of original total) after treatment with citrate does not become exopenicillinase. Exopenicillinase in these cells appears only under conditions permitting de novo penicillinase synthesis. By use of (14)C-labeled cells, it was shown that exopenicillinase consists of newly synthesized molecules which have not equilibrated with preformed membrane-bound enzyme.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
Citric acidBeta-lactamase 2ProteinBacillus cereus
Unknown
Not AvailableDetails