8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
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Shimada J, Suzuki F, Nonaka H, Karasawa A, Mizumoto H, Ohno T, Kubo K, Ishii A
8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
J Med Chem. 1991 Jan;34(1):466-9.
- PubMed ID
- 1992150 [ View in PubMed]
- Abstract
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- Binding Properties
Drug Target Property Measurement pH Temperature (°C) Caffeine Adenosine receptor A1 Ki (nM) >100000 N/A N/A Details Theophylline Adenosine receptor A1 Ki (nM) 23000 N/A N/A Details