TTD: Therapeutic Target Database.

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Chen X, Ji ZL, Chen YZ

TTD: Therapeutic Target Database.

Nucleic Acids Res. 2002 Jan 1;30(1):412-5.

PubMed ID

11752352 [ View in PubMed

]

Abstract

A number of proteins and nucleic acids have been explored as therapeutic targets. These targets are subjects of interest in different areas of biomedical and pharmaceutical research and in the development and evaluation of bioinformatics, molecular modeling, computer-aided drug design and analytical tools. A publicly accessible database that provides comprehensive information about these targets is therefore helpful to the relevant communities. The Therapeutic Target Database (TTD) is designed to provide information about the known therapeutic protein and nucleic acid targets described in the literature, the targeted disease conditions, the pathway information and the corresponding drugs/ligands directed at each of these targets. Cross-links to other databases are also introduced to facilitate the access of information about the sequence, 3D structure, function, nomenclature, drug/ligand binding properties, drug usage and effects, and related literature for each target. This database can be accessed at http://xin.cz3.nus.edu.sg/group/ttd/ttd.asp and it currently contains entries for 433 targets covering 125 disease conditions along with 809 drugs/ligands directed at each of these targets. Each entry can be retrieved through multiple methods including target name, disease name, drug/ligand name, drug/ligand function and drug therapeutic classification.

DrugBank Data that Cites this Article

Drugs

Cetuximab

Anakinra

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
(R)-Rolipram	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Protein	Humans	Unknown	Inhibitor	Details
(S)-Rolipram	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Protein	Humans	Unknown	Inhibitor	Details
1-Guanidinium-7-Aminoheptane	Deoxyhypusine synthase	Protein	Humans	Unknown	Inhibitor	Details
3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone	Fibroblast growth factor receptor 2	Protein	Humans	Unknown	Not Available	Details
3-Methylthiofentanyl	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Abatacept	T-lymphocyte activation antigen CD80	Protein	Humans	Yes	Antagonist	Details
Abatacept	T-lymphocyte activation antigen CD86	Protein	Humans	Yes	Antagonist	Details
Abciximab	Integrin beta-3	Protein	Humans	Yes	Antagonist	Details
Acebutolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Partial agonist	Details
Acenocoumarol	Vitamin K epoxide reductase complex subunit 1	Protein	Humans	Yes	Inhibitor	Details
Acepromazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Aceprometazine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Acetaminophen	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Acetaminophen	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Acetohydroxamic acid	Urease subunit alpha	Protein	Enterobacter aerogenes	Yes	Inhibitor	Details
Acetophenazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Adenosine	Adenosine receptor A3	Protein	Humans	Yes	Agonist	Details
Adenosine phosphate	Adenylate cyclase type 1	Protein	Humans	Unknown	Product of	Details
Alanine	4-aminobutyrate aminotransferase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Aldesleukin	Interleukin-2 receptor subunit alpha	Protein	Humans	Yes	Agonist Modulator	Details
Aldesleukin	Interleukin-2 receptor subunit beta	Protein	Humans	Yes	Agonist Modulator	Details
Alefacept	T-cell surface antigen CD2	Protein	Humans	Yes	Inhibitor Antibody Regulator	Details
Alemtuzumab	CAMPATH-1 antigen	Protein	Humans	Yes	Antibody	Details
Alendronic acid	Farnesyl pyrophosphate synthase	Protein	Humans	Yes	Inhibitor	Details
Alendronic acid	Receptor-type tyrosine-protein phosphatase S	Protein	Humans	Unknown	Inhibitor	Details
Alfacalcidol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Alfentanil	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Alimemazine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Alitretinoin	Retinoic acid receptor alpha	Protein	Humans	Yes	Agonist	Details
Allopurinol	Xanthine dehydrogenase/oxidase	Protein	Humans	Yes	Inhibitor	Details
Almitrine	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Yes	Binder	Details
Almotriptan	5-hydroxytryptamine receptor 1B	Protein	Humans	Unknown	Agonist	Details
Almotriptan	5-hydroxytryptamine receptor 1D	Protein	Humans	Unknown	Agonist	Details
Alosetron	5-hydroxytryptamine receptor 3A	Protein	Humans	Yes	Antagonist	Details
Alpha-1-proteinase inhibitor	Neutrophil elastase	Protein	Humans	Yes	Inhibitor	Details
Alprenolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Alsterpaullone	Cyclin-dependent kinase 1	Protein	Humans	Unknown	Inhibitor	Details
Alsterpaullone	Cyclin-dependent kinase 5	Protein	Humans	Unknown	Not Available	Details
Aluminium	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Unknown	Binder	Details
Aluminium monostearate	Troponin C, slow skeletal and cardiac muscles	Protein	Humans	Unknown	Stimulator	Details
Aluminium phosphate	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Unknown	Not Available	Details
Aluminum acetate	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Unknown	Not Available	Details
Alvimopan	Mu-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Alvocidib	Cyclin-dependent kinase 1	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Cyclin-dependent kinase 2	Protein	Humans	Unknown	Inhibitor	Details
Alvocidib	Cyclin-dependent kinase 4	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Cyclin-dependent kinase 5	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Cyclin-dependent kinase 6	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Cyclin-dependent kinase 7	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Cyclin-dependent kinase 8	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Cyclin-dependent kinase 9	Protein	Humans	Unknown	Not Available	Details
Alvocidib	Epidermal growth factor receptor	Protein	Humans	Unknown	Not Available	Details
Ambenonium	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Amiloride	Amiloride-sensitive sodium channel subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Amiloride	Urokinase-type plasminogen activator	Protein	Humans	Unknown	Inhibitor	Details
Aminocaproic acid	Plasminogen	Protein	Humans	Yes	Inhibitor	Details
Aminoglutethimide	Cholesterol side-chain cleavage enzyme, mitochondrial	Protein	Humans	Yes	Inhibitor	Details
Aminoglutethimide	Cytochrome P450 19A1	Protein	Humans	Yes	Inhibitor	Details
Aminolevulinic acid	Delta-aminolevulinic acid dehydratase	Protein	Humans	Yes	Inducer	Details
Aminophylline	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Protein	Humans	Yes	Inhibitor	Details
Amobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Amodiaquine	Histamine N-methyltransferase	Protein	Humans	Unknown	Inhibitor	Details
Amrinone	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Protein	Humans	Yes	Inhibitor	Details
Amsacrine	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Anakinra	Interleukin-1 receptor type 1	Protein	Humans	Yes	Antagonist	Details
Anileridine	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Anisindione	Vitamin K-dependent gamma-carboxylase	Protein	Humans	Yes	Inhibitor	Details
Anistreplase	Plasminogen	Protein	Humans	Yes	Activator	Details
Antithymocyte immunoglobulin (rabbit)	T-cell surface glycoprotein CD1a	Protein	Humans	Unknown	Inhibitor	Details
Antrafenine	Prostaglandin G/H synthase 2	Protein	Humans	Unknown	Inhibitor	Details
Apomorphine	Dopamine D1 receptor	Protein	Humans	Unknown	Agonist	Details
Apomorphine	Dopamine D2 receptor	Protein	Humans	Yes	Agonist	Details
Apomorphine	Dopamine D3 receptor	Protein	Humans	Yes	Agonist	Details
Apomorphine	Dopamine D4 receptor	Protein	Humans	Yes	Agonist	Details
Apomorphine	Dopamine D5 receptor	Protein	Humans	Unknown	Agonist	Details
Aprepitant	Neurokinin 1 receptor	Protein	Humans	Yes	Antagonist	Details
Arbaclofen	Gamma-aminobutyric acid type B receptor subunit 1	Protein	Humans	Yes	Agonist	Details
Arbaclofen Placarbil	Gamma-aminobutyric acid type B receptor subunit 1	Protein	Humans	Yes	Agonist	Details
Ardeparin	Heparin cofactor 2	Protein	Humans	Yes	Agonist	Details
Arformoterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Argatroban	Prothrombin	Protein	Humans	Yes	Inhibitor	Details
Aripiprazole	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist Partial agonist	Details
Aripiprazole lauroxil	Dopamine D2 receptor	Protein	Humans	Yes	Partial agonist	Details
Arsenic trioxide	Inhibitor of nuclear factor kappa-B kinase subunit beta	Protein	Humans	Yes	Inducer	Details
Ascorbic acid	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	Protein	Humans	Unknown	Cofactor	Details
Astemizole	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Atazanavir	Human immunodeficiency virus type 1 protease	Protein	Human immunodeficiency virus 1	Yes	Inhibitor	Details
Atenolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Atorvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Atovaquone	Dihydroorotate dehydrogenase (quinone), mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Atovaquone	Dihydroorotate dehydrogenase (quinone), mitochondrial	Protein	Plasmodium falciparum (isolate 3D7)	Yes	Inhibitor	Details
ATP	Tyrosine-protein kinase ABL1	Protein	Humans	Unknown	Inhibitor	Details
ATP	Tyrosine-protein kinase ABL2	Protein	Humans	Unknown	Inhibitor	Details
Auranofin	Peroxiredoxin-5, mitochondrial	Protein	Humans	Yes	Inhibitor	Details
Azacitidine	DNA (cytosine-5)-methyltransferase 1	Protein	Humans	Yes	Inhibitor	Details
Azatadine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Azilsartan medoxomil	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Bacitracin	Insulin-degrading enzyme	Protein	Humans	Yes	Inhibitor	Details
Balsalazide	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Bambuterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Basiliximab	Interleukin-2 receptor subunit alpha	Protein	Humans	Yes	Antibody	Details
Basiliximab	Interleukin-2 receptor subunit beta	Protein	Humans	Unknown	Antibody	Details
Bb-3497	Peptide deformylase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Benazepril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Bendroflumethiazide	Solute carrier family 12 member 3	Protein	Humans	Yes	Inhibitor	Details
Benzatropine	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Benzthiazide	Carbonic anhydrase 2	Protein	Humans	Unknown	Inhibitor	Details
Benzylpenicilloyl polylysine	High affinity immunoglobulin epsilon receptor subunit alpha	Protein	Humans	Yes	Agonist	Details
Benzylpenicilloyl polylysine	High affinity immunoglobulin epsilon receptor subunit gamma	Protein	Humans	Yes	Agonist	Details
Bepotastine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Betaxolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Betazole	Histamine H2 receptor	Protein	Humans	Yes	Agonist	Details
Bethanidine	Beta adrenergic receptor (Protein Group)	Protein group	Humans	Unknown	Antagonist	Details
Bevacizumab	Vascular endothelial growth factor A	Protein	Humans	Yes	Not Available	Details
Bezafibrate	Peroxisome proliferator-activated receptor alpha	Protein	Humans	Yes	Agonist	Details
Bicalutamide	Androgen receptor	Protein	Humans	Yes	Antagonist	Details
Biperiden	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Bisoprolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Bivalirudin	Prothrombin	Protein	Humans	Yes	Inhibitor	Details
Bopindolol	5-hydroxytryptamine receptor 1A	Protein	Humans	Unknown	Not Available	Details
Bopindolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist Partial agonist	Details
Bopindolol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Antagonist Partial agonist	Details
Bopindolol	Beta-3 adrenergic receptor	Protein	Humans	Unknown	Not Available	Details
Bosentan	Endothelin B receptor	Protein	Humans	Yes	Antagonist	Details
Bosentan	Endothelin-1 receptor	Protein	Humans	Yes	Antagonist	Details
Botulinum toxin type B	Vesicle-associated membrane protein 1	Protein	Humans	Yes	Binder	Details
Botulinum toxin type B	Vesicle-associated membrane protein 2	Protein	Humans	Yes	Binder	Details
Brimonidine	Alpha-2A adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Bromfenac	Prostaglandin G/H synthase 1	Protein	Humans	Unknown	Inhibitor	Details
Bromocriptine	Dopamine D2 receptor	Protein	Humans	Yes	Agonist	Details
Bromodiphenhydramine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Brompheniramine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Buclizine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Budesonide	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Bumetanide	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Buprenorphine	Mu-type opioid receptor	Protein	Humans	Yes	Partial agonist	Details
Bupropion	Sodium-dependent dopamine transporter	Protein	Humans	Yes	Inhibitor	Details
Bupropion	Sodium-dependent noradrenaline transporter	Protein	Humans	Yes	Inhibitor	Details
Buspirone	5-hydroxytryptamine receptor 1A	Protein	Humans	Yes	Partial agonist	Details
Butalbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Butenafine	Squalene monooxygenase	Protein	Humans	Yes	Inhibitor	Details
Butobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Butorphanol	Delta-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Cabergoline	Dopamine D2 receptor	Protein	Humans	Yes	Agonist	Details
Caffeine	Adenosine receptor A2a	Protein	Humans	Yes	Antagonist	Details
Calcifediol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Calcipotriol	Vitamin D3 receptor	Protein	Humans	Unknown	Antagonist	Details
Calcitriol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Camptothecin	DNA topoisomerase 1	Protein	Humans	Unknown	Inhibitor	Details
Canaline	Ornithine aminotransferase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Candesartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Candesartan cilexetil	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Candoxatril	Neprilysin	Protein	Humans	Yes	Inhibitor	Details
Capecitabine	Thymidylate synthase	Protein	Humans	Yes	Inhibitor	Details
Capromab pendetide	Glutamate carboxypeptidase 2	Protein	Humans	Yes	Other/unknown	Details
Captopril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Carbamoylcholine	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Agonist	Details
Carbenoxolone	Corticosteroid 11-beta-dehydrogenase isozyme 1	Protein	Humans	Unknown	Inhibitor	Details
Carbetocin	Oxytocin receptor	Protein	Humans	Yes	Agonist	Details
Carbidopa	Aromatic-L-amino-acid decarboxylase	Protein	Humans	Yes	Inhibitor	Details
Carbimazole	Thyroid peroxidase	Protein	Humans	Yes	Inhibitor	Details
Carbinoxamine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Carphenazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Carprofen	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Carteolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist Partial agonist	Details
Carteolol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Cerivastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Cerulenin	Fatty acid synthase	Protein	Humans	Yes	Inhibitor	Details
Cetrorelix	Gonadotropin-releasing hormone receptor	Protein	Humans	Yes	Antagonist	Details
Cetuximab	Epidermal growth factor receptor	Protein	Humans	Yes	Binder	Details
Cevimeline	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Agonist	Details
Chlormerodrin	Succinate-semialdehyde dehydrogenase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Chlormezanone	Translocator protein	Protein	Humans	Yes	Agonist	Details
Chloroquine	Glutathione S-transferase A2	Protein	Humans	Unknown	Inhibitor	Details
Chlorothiazide	Carbonic anhydrase 2	Protein	Humans	Yes	Inhibitor	Details
Chlorotrianisene	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Chlorpheniramine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Chlorpromazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Chlorprothixene	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Chlorthalidone	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Cholecalciferol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Choriogonadotropin alfa	Follicle-stimulating hormone receptor	Protein	Humans	Yes	Binder	Details
Cilastatin	Dipeptidase 1	Protein	Humans	Yes	Inhibitor	Details
Cilazapril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Cilazaprilat	Angiotensin-converting enzyme	Protein	Humans	Yes	Not Available	Details
Cilostazol	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Protein	Humans	Yes	Inhibitor	Details
Cimetidine	Histamine H2 receptor	Protein	Humans	Yes	Antagonist	Details
Cinacalcet	Extracellular calcium-sensing receptor	Protein	Humans	Yes	Agonist	Details
Cinalukast	Cysteinyl leukotriene receptor 1	Protein	Humans	Yes	Antagonist	Details
Cinchocaine	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Cinnarizine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Ciprofloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Unknown	Inhibitor	Details
Cisapride	5-hydroxytryptamine receptor 4	Protein	Humans	Yes	Agonist	Details
Clemastine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Clenbuterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Clidinium	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Clodronic acid	ADP/ATP translocase 1	Protein	Humans	Yes	Inhibitor	Details
Clofedanol	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Clomifene	Estrogen receptor alpha	Protein	Humans	Yes	Antagonist Agonist	Details
Clozapine	Dopamine D1 receptor	Protein	Humans	Unknown	Antagonist	Details
Clozapine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Clozapine	Dopamine D4 receptor	Protein	Humans	Unknown	Antagonist	Details
Clozapine	Histamine H1 receptor	Protein	Humans	Unknown	Antagonist	Details
Clozapine	Histamine H4 receptor	Protein	Humans	No	Antagonist	Details
Clozapine	Neuron-specific vesicular protein calcyon	Protein	Humans	Unknown	Unknown	Details
Coagulation Factor IX (Recombinant)	Coagulation factor X	Protein	Humans	Yes	Activator	Details
Coagulation Factor IX Human	Coagulation factor X	Protein	Humans	Yes	Activator	Details
Conivaptan	Vasopressin V1a receptor	Protein	Humans	Yes	Antagonist	Details
Conivaptan	Vasopressin V2 receptor	Protein	Humans	Yes	Antagonist	Details
Cyclizine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Cycloserine	D-alanine--D-alanine ligase A	Protein	Escherichia coli (strain K12)	Yes	Inhibitor	Details
Cyclothiazide	Carbonic anhydrase 2	Protein	Humans	Unknown	Inhibitor	Details
Cycrimine	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Cyproheptadine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
D-Serine	Glycine receptor subunit alpha-1	Protein	Humans	Unknown	Not Available	Details
Daclizumab	Interleukin-2 receptor subunit alpha	Protein	Humans	Yes	Antibody	Details
Daclizumab	Interleukin-2 receptor subunit beta	Protein	Humans	Yes	Antibody	Details
Danazol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Dantrolene	Ryanodine receptor 1	Protein	Humans	Yes	Antagonist	Details
Darbepoetin alfa	Erythropoietin receptor	Protein	Humans	Yes	Agonist	Details
Darifenacin	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Antagonist	Details
Dazoxiben	Thromboxane-A synthase	Protein	Humans	Unknown	Inhibitor	Details
Decamethonium	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Partial agonist	Details
Decitabine	DNA (cytosine-5)-methyltransferase 1	Protein	Humans	Yes	Inhibitor	Details
Demecarium	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Denileukin diftitox	Interleukin-2 receptor subunit beta	Protein	Humans	Yes	Agonist	Details
Desipramine	Sodium-dependent noradrenaline transporter	Protein	Humans	Yes	Inhibitor	Details
Deslanoside	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Yes	Inhibitor	Details
Desloratadine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Desmopressin	Vasopressin V2 receptor	Protein	Humans	Yes	Agonist	Details
Desogestrel	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Desoxycorticosterone pivalate	Mineralocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Dexamethasone	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Dexamethasone	Nitric oxide synthase, inducible	Protein	Humans	Unknown	Negative modulator	Details
Dexbrompheniramine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Dexmethylphenidate	Sodium-dependent dopamine transporter	Protein	Humans	Yes	Inhibitor	Details
Dexrazoxane	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Dextroamphetamine	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Dextromethorphan	Sigma non-opioid intracellular receptor 1	Protein	Humans	Yes	Agonist	Details
Dextropropoxyphene	Kappa-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Dextropropoxyphene	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Dezocine	Kappa-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Diamorphine	Delta-type opioid receptor	Protein	Humans	Unknown	Agonist	Details
Diclofenac	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Dicoumarol	Vitamin K epoxide reductase complex subunit 1	Protein	Humans	Yes	Inhibitor	Details
Dicyclomine	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Dienestrol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Diethylcarbamazine	Arachidonate 5-lipoxygenase	Protein	Humans	Yes	Inhibitor	Details
Diethylstilbestrol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Diflunisal	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Dihomo-gamma-linolenic acid	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Dihydroergotamine	5-hydroxytryptamine receptor 1D	Protein	Humans	Yes	Agonist	Details
Dihydroergotamine	5-hydroxytryptamine receptor 2B	Protein	Humans	Unknown	Agonist	Details
Dihydrotachysterol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Dimenhydrinate	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Dinoprost tromethamine	Prostacyclin receptor	Protein	Humans	Unknown	Antagonist	Details
Dinoprostone	Prostaglandin E2 receptor EP2 subtype	Protein	Humans	Yes	Agonist	Details
Diphemanil	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Antagonist	Details
Diphenhydramine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Diphenoxylate	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Diphenylpyraline	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Dipivefrin	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Dipyridamole	Adenosine deaminase	Protein	Humans	Yes	Inhibitor	Details
Dipyridamole	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Protein	Humans	Yes	Inhibitor	Details
Dipyridamole	cGMP-specific 3',5'-cyclic phosphodiesterase	Protein	Humans	Yes	Inhibitor	Details
Disopyramide	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Dobutamine	Beta-1 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Dofetilide	Potassium voltage-gated channel subfamily H member 2	Protein	Humans	Yes	Inhibitor	Details
Dolasetron	5-hydroxytryptamine receptor 3A	Protein	Humans	Yes	Antagonist	Details
Domperidone	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Donepezil	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Dopamine	Dopamine D2 receptor	Protein	Humans	Yes	Agonist	Details
Dorzolamide	Carbonic anhydrase 2	Protein	Humans	Yes	Inhibitor	Details
Doxacurium	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Doxepin	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Doxorubicin	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Doxylamine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Dronabinol	Cannabinoid receptor 1	Protein	Humans	Yes	Agonist	Details
Drostanolone	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Drotrecogin alfa	Coagulation factor V	Protein	Humans	Yes	Inhibitor	Details
Drotrecogin alfa	Coagulation factor VIII	Protein	Humans	Yes	Inhibitor	Details
Duloxetine	Sodium-dependent noradrenaline transporter	Protein	Humans	Yes	Inhibitor	Details
Dutasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 1	Protein	Humans	Yes	Inhibitor	Details
Dutasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 2	Protein	Humans	Yes	Inhibitor	Details
Dydrogesterone	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Dyphylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Protein	Humans	Yes	Inhibitor	Details
Echothiophate	Cholinesterase	Protein	Humans	Yes	Inhibitor	Details
Eculizumab	Complement C5	Protein	Humans	Yes	Antibody	Details
Edrophonium	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Efalizumab	Integrin alpha-L	Protein	Humans	Yes	Antibody	Details
Eletriptan	5-hydroxytryptamine receptor 1B	Protein	Humans	Yes	Agonist	Details
Eletriptan	5-hydroxytryptamine receptor 1D	Protein	Humans	Yes	Agonist	Details
Emedastine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Enalapril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Enalkiren	Renin	Protein	Humans	Unknown	Inhibitor	Details
Encainide	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Enoxacin	DNA topoisomerase 2-alpha	Protein	Humans	No	Inhibitor	Details
Enprofylline	Adenosine receptor A2b	Protein	Humans	Yes	Antagonist	Details
Enprofylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Protein	Humans	Yes	Inhibitor	Details
Entacapone	Catechol O-methyltransferase	Protein	Humans	Yes	Inhibitor	Details
Epinastine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Epinephrine	Beta-1 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Epinephrine	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Eplerenone	Mineralocorticoid receptor	Protein	Humans	Yes	Antagonist	Details
Epoprostenol	Prostacyclin receptor	Protein	Humans	Yes	Agonist	Details
Eprosartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Ergocalciferol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Ergotamine	5-hydroxytryptamine receptor 2A	Protein	Humans	Yes	Agonist	Details
Erlotinib	Epidermal growth factor receptor	Protein	Humans	Yes	Antagonist	Details
Erythropoietin	Erythropoietin receptor	Protein	Humans	Yes	Agonist	Details
Esmolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Esomeprazole	Potassium-transporting ATPase alpha chain 1	Protein	Humans	Yes	Inhibitor	Details
Estradiol acetate	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estradiol benzoate	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estradiol cypionate	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estradiol dienanthate	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estradiol valerate	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estriol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estriol tripropionate	Estrogen receptor alpha	Protein	Humans	Yes	Not Available	Details
Estrone	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Estrone sulfate	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Etacrynic acid	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Etanercept	Tumor necrosis factor	Protein	Humans	Yes	Inhibitor Antibody	Details
Ethanol	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Agonist	Details
Ethinamate	Carbonic anhydrase 2	Protein	Humans	Yes	Inhibitor	Details
Ethinylestradiol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Ethionamide	Enoyl-[acyl-carrier-protein] reductase [NADH]	Protein	Mycobacterium tuberculosis	Yes	Inhibitor	Details
Ethosuximide	Voltage-dependent T-type calcium channel subunit alpha-1G	Protein	Humans	Yes	Inhibitor	Details
Ethotoin	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Ethylmorphine	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Ethynodiol diacetate	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Etidronic acid	Receptor-type tyrosine-protein phosphatase S	Protein	Humans	Unknown	Inhibitor	Details
Etodolac	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Etomidate	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Agonist	Details
Etonogestrel	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Etoposide	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Etoricoxib	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Etorphine	Delta-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Etorphine	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Everolimus	Serine/threonine-protein kinase mTOR	Protein	Humans	Yes	Inhibitor	Details
Exemestane	Cytochrome P450 19A1	Protein	Humans	Yes	Inhibitor	Details
Exenatide	Glucagon-like peptide 1 receptor	Protein	Humans	Yes	Agonist	Details
Ezetimibe	Niemann-Pick C1-like protein 1	Protein	Humans	Yes	Inhibitor	Details
Famotidine	Histamine H2 receptor	Protein	Humans	Yes	Antagonist	Details
Felbamate	Glutamate receptor ionotropic, NMDA 2A	Protein	Humans	Yes	Antagonist	Details
Felbamate	Glutamate receptor ionotropic, NMDA 2B	Protein	Humans	Yes	Antagonist	Details
Felodipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	Protein	Humans	Yes	Inhibitor	Details
Felodipine	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Inhibitor	Details
Felodipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Felypressin	Vasopressin V1a receptor	Protein	Humans	Yes	Agonist	Details
Fenofibrate	Peroxisome proliferator-activated receptor alpha	Protein	Humans	Yes	Agonist	Details
Fenoldopam	Dopamine D1 receptor	Protein	Humans	Yes	Agonist	Details
Fenoterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Fentanyl	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Fesoterodine	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Antagonist	Details
Fidarestat	Aldose reductase	Protein	Humans	Unknown	Inhibitor	Details
Flecainide	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Fleroxacin	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Flunarizine	Voltage-dependent T-type calcium channel subunit alpha-1H	Protein	Humans	Yes	Inhibitor	Details
Flunisolide	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Fluorouracil	Thymidylate synthase	Protein	Humans	Yes	Other/unknown	Details
Fluoxetine	Sodium-dependent serotonin transporter	Protein	Humans	Yes	Inhibitor	Details
Fluoxymesterone	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Flupentixol	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Fluphenazine	Dopamine D1 receptor	Protein	Humans	Yes	Antagonist	Details
Fluphenazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Fluspirilene	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Flutamide	Androgen receptor	Protein	Humans	Yes	Antagonist	Details
Fluticasone propionate	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Fluvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Folic acid	Folate receptor beta	Protein	Humans	Unknown	Binder	Details
Folic acid	Folate receptor gamma	Protein	Humans	Unknown	Binder	Details
Follitropin	Follicle-stimulating hormone receptor	Protein	Humans	Yes	Agonist	Details
Forasartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Fosamprenavir	Human immunodeficiency virus type 1 protease	Protein	Human immunodeficiency virus 1	Yes	Inhibitor	Details
Fosinopril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Fosphenytoin	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Freselestat	Neutrophil elastase	Protein	Humans	Unknown	Inhibitor	Details
Frovatriptan	5-hydroxytryptamine receptor 1B	Protein	Humans	Yes	Agonist	Details
Frovatriptan	5-hydroxytryptamine receptor 1D	Protein	Humans	Yes	Agonist	Details
Fulvestrant	Estrogen receptor alpha	Protein	Humans	Yes	Antagonist	Details
Fumagillin	Methionine aminopeptidase 2	Protein	Humans	Unknown	Ligand	Details
Furosemide	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Gallamine triethiodide	Muscarinic acetylcholine receptor M2	Protein	Humans	Yes	Antagonist	Details
Gefitinib	Epidermal growth factor receptor	Protein	Humans	Yes	Antagonist	Details
Gemcitabine	Thymidylate synthase	Protein	Humans	Unknown	Inhibitor	Details
Gemtuzumab ozogamicin	Myeloid cell surface antigen CD33	Protein	Humans	Yes	Antibody Regulator	Details
Glucagon	Glucagon receptor	Protein	Humans	Yes	Agonist	Details
Glycine	Glutamate receptor ionotropic, NMDA 2A	Protein	Humans	Unknown	Antagonist	Details
Glycopyrronium	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Glyphosate	3-phosphoshikimate 1-carboxyvinyltransferase	Protein	Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	Unknown	Inhibitor	Details
Gonadorelin	Gonadotropin-releasing hormone receptor	Protein	Humans	Yes	Agonist	Details
Granisetron	5-hydroxytryptamine receptor 3A	Protein	Humans	Yes	Antagonist	Details
Guanine	GTP cyclohydrolase 1	Protein	Humans	Unknown	Inhibitor	Details
Hadacidin	Adenylosuccinate synthetase	Protein	Plasmodium falciparum	Unknown	Inhibitor	Details
Haloperidol	Dopamine D1 receptor	Protein	Humans	Unknown	Antagonist	Details
Haloperidol	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Haloperidol	Glutamate receptor ionotropic, NMDA 2B	Protein	Humans	Unknown	Antagonist	Details
Heparin	Antithrombin-III	Protein	Humans	Yes	Potentiator	Details
Hexafluronium	Cholinesterase	Protein	Humans	Yes	Inhibitor	Details
Hexobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Hexylcaine	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Histamine	Histamine H2 receptor	Protein	Humans	Yes	Agonist	Details
Homatropine methylbromide	Muscarinic acetylcholine receptor M5	Protein	Humans	Yes	Antagonist	Details
Hydralazine	Prolyl 4-hydroxylase subunit alpha-1	Protein	Humans	Unknown	Inhibitor	Details
Hydrochlorothiazide	Solute carrier family 12 member 3	Protein	Humans	Yes	Inhibitor	Details
Hydrocodone	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Hydroflumethiazide	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Hydromorphone	Delta-type opioid receptor	Protein	Humans	Yes	Partial agonist	Details
Hydroxocobalamin	Methylmalonyl-CoA mutase, mitochondrial	Protein	Humans	Yes	Cofactor	Details
Hydroxyfasudil	Rho-associated protein kinase 1	Protein	Humans	Unknown	Inhibitor	Details
Hymenialdisine	Cyclin-dependent kinase 1	Protein	Humans	Unknown	Not Available	Details
Hymenialdisine	Cyclin-dependent kinase 2	Protein	Humans	Unknown	Inhibitor	Details
Hymenialdisine	Cyclin-dependent kinase 5	Protein	Humans	Unknown	Inhibitor	Details
Hyperforin	Arachidonate 5-lipoxygenase	Protein	Humans	Unknown	Inhibitor	Details
Hyperforin	Prostaglandin G/H synthase 1	Protein	Humans	Unknown	Inhibitor	Details
Ibandronate	Farnesyl pyrophosphate synthase	Protein	Humans	Yes	Inhibitor	Details
Ibritumomab tiuxetan	B-lymphocyte antigen CD20	Protein	Humans	Yes	Antibody Regulator	Details
Ibuprofen	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Ibuprofen	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Ibutilide	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Activator	Details
Icatibant	B2 bradykinin receptor	Protein	Humans	Yes	Antagonist	Details
Idarubicin	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Imiquimod	Toll-like receptor 7	Protein	Humans	Yes	Agonist	Details
Immucillin-G	Purine nucleoside phosphorylase	Protein	Humans	Unknown	Not Available	Details
Indecainide	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Indirubin-3'-monoxime	Cyclin-dependent kinase 1	Protein	Humans	Unknown	Binder	Details
Indirubin-3'-monoxime	Cyclin-dependent kinase 2	Protein	Humans	Unknown	Inhibitor	Details
Indirubin-3'-monoxime	Cyclin-dependent kinase 5	Protein	Humans	Unknown	Inhibitor	Details
Infliximab	Tumor necrosis factor	Protein	Humans	Yes	Inhibitor	Details
Insulin detemir	Insulin receptor	Protein	Humans	Yes	Agonist	Details
Insulin glargine	Insulin receptor	Protein	Humans	Yes	Agonist	Details
Insulin human	Insulin receptor	Protein	Humans	Yes	Agonist	Details
Insulin lispro	Insulin receptor	Protein	Humans	Yes	Agonist	Details
Insulin pork	Insulin receptor	Protein	Humans	Yes	Binder	Details
Interferon alfa-2b	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Binder	Details
Interferon alfa-2b	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Binder	Details
Interferon alfa-n1	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Agonist	Details
Interferon alfa-n1	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Agonist	Details
Interferon alfa-n3	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Agonist	Details
Interferon alfa-n3	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Agonist	Details
Interferon alfacon-1	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Binder	Details
Interferon alfacon-1	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Binder	Details
Interferon beta-1b	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Agonist	Details
Interferon beta-1b	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Agonist	Details
Interferon gamma-1b	Interferon gamma receptor 1	Protein	Humans	Yes	Binder	Details
Interferon gamma-1b	Interferon gamma receptor 2	Protein	Humans	Yes	Binder	Details
Inulin	Cycloinulo-oligosaccharide fructanotransferase	Protein	Paenibacillus macerans	No	Binder	Details
Irbesartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Irinotecan	DNA topoisomerase 1	Protein	Humans	Yes	Inhibitor	Details
Irinotecan	DNA topoisomerase I, mitochondrial	Protein	Humans	Yes	Inhibitor	Details
Iron Dextran	Hemoglobin subunit alpha	Protein	Humans	Yes	Activator	Details
Iron Dextran	Hemoglobin subunit beta	Protein	Humans	Yes	Activator	Details
Isocarboxazid	Amine oxidase [flavin-containing] A	Protein	Humans	Yes	Inhibitor	Details
Isoflurophate	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Isoniazid	Enoyl-[acyl-carrier-protein] reductase [NADH]	Protein	Mycobacterium tuberculosis	Yes	Adduct	Details
Isoprenaline	Beta-1 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Isoprenaline	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist Binder	Details
Isradipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	Protein	Humans	Yes	Inhibitor	Details
Isradipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Itraconazole	Lanosterol 14-alpha demethylase	Protein	Humans	Yes	Inhibitor	Details
Ketoprofen	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Labetalol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Labetalol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Lansoprazole	Potassium-transporting ATPase alpha chain 1	Protein	Humans	Yes	Inhibitor	Details
Lapatinib	Epidermal growth factor receptor	Protein	Humans	Yes	Antagonist	Details
Lapatinib	Receptor tyrosine-protein kinase erbB-2	Protein	Humans	Yes	Antagonist	Details
Leflunomide	Dihydroorotate dehydrogenase (quinone), mitochondrial	Protein	Humans	Yes	Inhibitor	Details
Letrozole	Cytochrome P450 19A1	Protein	Humans	Yes	Antagonist	Details
Levacetylmethadol	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Levobunolol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Levocabastine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Levocarnitine	Carnitine O-palmitoyltransferase 1, liver isoform	Protein	Humans	Unknown	Activator	Details
Levomenthol	Transient receptor potential cation channel subfamily A member 1	Protein	Humans	Yes	Inducer	Details
Levomenthol	Transient receptor potential cation channel subfamily M member 8	Protein	Humans	Yes	Inducer	Details
Levosimendan	Troponin C, slow skeletal and cardiac muscles	Protein	Humans	Yes	Potentiator	Details
Levothyroxine	Thyroid hormone receptor alpha	Protein	Humans	Yes	Agonist	Details
Licofelone	Arachidonate 5-lipoxygenase	Protein	Humans	Unknown	Not Available	Details
Liothyronine	Thyroid hormone receptor alpha	Protein	Humans	Yes	Agonist	Details
Liotrix	Thyroid hormone receptor alpha	Protein	Humans	Yes	Agonist	Details
Lisinopril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Lisuride	Dopamine D2 receptor	Protein	Humans	Yes	Agonist	Details
Lomefloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Unknown	Inhibitor	Details
Lonapegsomatropin	Growth hormone receptor	Protein	Humans	Yes	Ligand	Details
Loperamide	Delta-type opioid receptor	Protein	Humans	Unknown	Agonist	Details
Loperamide	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Lopinavir	Human immunodeficiency virus type 1 protease	Protein	Human immunodeficiency virus 1	Yes	Inhibitor	Details
Loratadine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Losartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Loteprednol etabonate	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Lovastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Loxapine	Dopamine D1 receptor	Protein	Humans	Unknown	Antagonist	Details
Loxapine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Lubiprostone	Chloride channel protein 2	Protein	Humans	Yes	Inducer	Details
Lucanthone	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Lumiracoxib	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Lutropin alfa	Lutropin-choriogonadotropic hormone receptor	Protein	Humans	Yes	Agonist	Details
Lypressin	Vasopressin V2 receptor	Protein	Humans	Yes	Not Available	Details
Maraviroc	C-C chemokine receptor type 5	Protein	Humans	Yes	Antagonist Inhibitor	Details
Marimastat	72 kDa type IV collagenase	Protein	Humans	Yes	Inhibitor	Details
Marimastat	Interstitial collagenase	Protein	Humans	Yes	Inhibitor	Details
Marimastat	Matrix metalloproteinase-9	Protein	Humans	Yes	Inhibitor	Details
Marimastat	Stromelysin-1	Protein	Humans	Yes	Antagonist	Details
Masoprocol	Arachidonate 5-lipoxygenase	Protein	Humans	Yes	Inhibitor	Details
Mecamylamine	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Medroxyprogesterone acetate	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Medrysone	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Mefenamic acid	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Megestrol acetate	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Melatonin	Melatonin receptor type 1A	Protein	Humans	Yes	Agonist	Details
Menotropins	Follicle-stimulating hormone receptor	Protein	Humans	Yes	Binder	Details
Mephenytoin	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Meprobamate	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Agonist	Details
Mequitazine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Mercaptopurine	Inosine-5'-monophosphate dehydrogenase (Protein Group)	Protein group	Humans	Unknown	Inhibitor	Details
Mesalazine	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Mesoridazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Mestranol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Metamizole	Prostaglandin G/H synthase 1	Protein	Humans	Unknown	Not Available	Details
Methadyl acetate	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Metharbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Methdilazine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Methimazole	Thyroid peroxidase	Protein	Humans	Yes	Substrate Inhibitor	Details
Methohexital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Antagonist	Details
Methotrexate	Dihydrofolate reductase	Protein	Humans	Yes	Inhibitor	Details
Methoxamine	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Agonist	Details
Methoxyflurane	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Agonist	Details
Methscopolamine bromide	Muscarinic acetylcholine receptor M2	Protein	Humans	Yes	Antagonist	Details
Methyclothiazide	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Methylergometrine	Dopamine D1 receptor	Protein	Humans	Yes	Antagonist	Details
Methylphenidate	Sodium-dependent dopamine transporter	Protein	Humans	Yes	Inhibitor	Details
Methylphenobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Methylprednisolone	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Methyltestosterone	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Methyprylon	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Agonist	Details
Methysergide	5-hydroxytryptamine receptor 2C	Protein	Humans	Yes	Antagonist	Details
Metocurine	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Metocurine iodide	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Metolazone	Solute carrier family 12 member 3	Protein	Humans	Yes	Inhibitor	Details
Metoprolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Metyrapone	Cytochrome P450 11B1, mitochondrial	Protein	Humans	Yes	Inhibitor	Details
Metyrosine	Tyrosine 3-monooxygenase	Protein	Humans	Yes	Binder	Details
Mevastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Mexiletine	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1G	Protein	Humans	Yes	Inhibitor	Details
Mifepristone	Progesterone receptor	Protein	Humans	Yes	Antagonist	Details
Miglitol	Maltase-glucoamylase, intestinal	Protein	Humans	Yes	Antagonist Inhibitor	Details
Miglustat	Ceramide glucosyltransferase	Protein	Humans	Yes	Inhibitor	Details
Milrinone	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Protein	Humans	Yes	Inhibitor	Details
Minaprine	5-hydroxytryptamine receptor 2B	Protein	Humans	Yes	Antagonist	Details
Mipomersen	mRNA of ApoB-100	Nucleotide	Humans	Yes	Binder	Details
Mitoxantrone	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Mivacurium	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Moclobemide	Amine oxidase [flavin-containing] A	Protein	Humans	Yes	Antagonist Inhibitor	Details
Moexipril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Molindone	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Mometasone	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Mometasone furoate	Glucocorticoid receptor	Protein	Humans	Yes	Not Available	Details
Montelukast	Cysteinyl leukotriene receptor 1	Protein	Humans	Yes	Antagonist	Details
Moricizine	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Morphine	Delta-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Morphine	Mu-type opioid receptor	Protein	Humans	Yes	Agonist Regulator	Details
Moxifloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Unknown	Inhibitor	Details
Muromonab	T-cell surface glycoprotein CD3 epsilon chain	Protein	Humans	Yes	Binder	Details
N-Acetylglucosamine	Alpha-N-acetylglucosaminidase	Protein	Humans	Unknown	Activator	Details
Nabilone	Cannabinoid receptor 1	Protein	Humans	Yes	Partial agonist	Details
Nabumetone	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
NADH	NADH-ubiquinone oxidoreductase chain 1	Protein	Humans	Unknown	Binder	Details
NADH	NADH-ubiquinone oxidoreductase chain 2	Protein	Humans	Unknown	Binder	Details
NADH	NADH-ubiquinone oxidoreductase chain 3	Protein	Humans	Unknown	Binder	Details
Nadolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Nadolol	Beta-2 adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Nafarelin	Gonadotropin-releasing hormone receptor	Protein	Humans	Yes	Agonist	Details
Naftifine	Squalene monooxygenase	Protein	Humans	Yes	Inhibitor	Details
Nalbuphine	Delta-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Naloxone	Mu-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Naltrexone	Delta-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Naltrexone	Kappa-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Naltrexone	Mu-type opioid receptor	Protein	Humans	Yes	Antagonist	Details
Nandrolone phenpropionate	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Naratriptan	5-hydroxytryptamine receptor 1B	Protein	Humans	Yes	Agonist	Details
Naratriptan	5-hydroxytryptamine receptor 1D	Protein	Humans	Yes	Agonist	Details
Naratriptan	5-hydroxytryptamine receptor 1F	Protein	Humans	Yes	Agonist	Details
Natalizumab	Integrin alpha-4	Protein	Humans	Yes	Antibody	Details
Natalizumab	Intercellular adhesion molecule 1	Protein	Humans	Unknown	Ligand	Details
Nebivolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Nefazodone	5-hydroxytryptamine receptor 2C	Protein	Humans	Yes	Antagonist	Details
Nefazodone	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Other/unknown	Details
Nelfinavir	HIV-1 protease	Protein	Human Immunodeficiency Virus	Yes	Inhibitor	Details
Neostigmine	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Nesiritide	Atrial natriuretic peptide receptor 1	Protein	Humans	Unknown	Binder	Details
Nicardipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	Protein	Humans	Yes	Inhibitor	Details
Nicardipine	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Inhibitor	Details
Nicardipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Nicotinamide	Poly [ADP-ribose] polymerase 1	Protein	Humans	Unknown	Binder	Details
Nifedipine	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Inhibitor	Details
Nifedipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Nilutamide	Androgen receptor	Protein	Humans	Yes	Antagonist	Details
Nilvadipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	Protein	Humans	Yes	Inhibitor	Details
Nimesulide	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Nimodipine	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Inhibitor	Details
Nimodipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Nisoldipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	Protein	Humans	Yes	Inhibitor	Details
Nisoldipine	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Inhibitor	Details
Nisoldipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Nitisinone	4-hydroxyphenylpyruvate dioxygenase	Protein	Humans	Yes	Inhibitor	Details
Nitrendipine	Voltage-dependent calcium channel subunit alpha-2/delta-1	Protein	Humans	Yes	Inhibitor	Details
Nitrendipine	Voltage-dependent L-type calcium channel subunit alpha-1C	Protein	Humans	Yes	Inhibitor	Details
Nitrendipine	Voltage-dependent L-type calcium channel subunit beta-2	Protein	Humans	Yes	Inhibitor	Details
Nizatidine	Histamine H2 receptor	Protein	Humans	Yes	Antagonist	Details
Norepinephrine	Beta-1 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Norfloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Unknown	Inhibitor	Details
Norgestimate	Progesterone receptor	Protein	Humans	Yes	Agonist	Details
Olanzapine	5-hydroxytryptamine receptor 2A	Protein	Humans	Yes	Antagonist	Details
Olanzapine	5-hydroxytryptamine receptor 2C	Protein	Humans	Unknown	Antagonist	Details
Olanzapine	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Olanzapine	Dopamine D1 receptor	Protein	Humans	Unknown	Antagonist	Details
Olanzapine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Olanzapine	Dopamine D3 receptor	Protein	Humans	Unknown	Antagonist	Details
Olanzapine	Dopamine D4 receptor	Protein	Humans	Unknown	Antagonist	Details
Olanzapine	Histamine H1 receptor	Protein	Humans	Unknown	Antagonist	Details
Olmesartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Olomoucine	Cyclin-dependent kinase 1	Protein	Humans	Unknown	Binder	Details
Olomoucine	Cyclin-dependent kinase 2	Protein	Humans	Unknown	Inhibitor	Details
Olomoucine	Cyclin-dependent kinase 5	Protein	Humans	Unknown	Inhibitor	Details
Olopatadine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Ondansetron	5-hydroxytryptamine receptor 3A	Protein	Humans	Yes	Antagonist	Details
Oprelvekin	Interleukin-11 receptor subunit alpha	Protein	Humans	Yes	Agonist	Details
Orciprenaline	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Orotic acid	Dihydroorotase	Protein	Escherichia coli (strain K12)	Unknown	Inhibitor	Details
Ouabain	Sodium/potassium-transporting ATPase subunit alpha-1	Protein	Humans	Yes	Inhibitor	Details
Oxandrolone	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Oxprenolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Oxycodone	Delta-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Oxymorphone	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Oxyphenonium	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Palifermin	Fibroblast growth factor receptor 2	Protein	Humans	Yes	Agonist Binder	Details
Paliperidone	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Palonosetron	5-hydroxytryptamine receptor 3A	Protein	Humans	Yes	Antagonist	Details
Pamidronic acid	Farnesyl pyrophosphate synthase	Protein	Humans	Yes	Inhibitor	Details
Panitumumab	Epidermal growth factor receptor	Protein	Humans	Yes	Suppressor	Details
Paricalcitol	Vitamin D3 receptor	Protein	Humans	Yes	Agonist	Details
Pefloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Unknown	Inhibitor	Details
Peginterferon alfa-2a	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Agonist	Details
Peginterferon alfa-2a	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Agonist	Details
Peginterferon alfa-2b	Interferon alpha/beta receptor 1	Protein	Humans	Yes	Agonist	Details
Peginterferon alfa-2b	Interferon alpha/beta receptor 2	Protein	Humans	Yes	Agonist	Details
Pegvisomant	Growth hormone receptor	Protein	Humans	Yes	Antagonist	Details
Pemetrexed	Dihydrofolate reductase	Protein	Humans	Yes	Inhibitor	Details
Pemetrexed	Thymidylate synthase	Protein	Humans	Yes	Inhibitor	Details
Penciclovir	DNA polymerase catalytic subunit	Protein	HHV-1	Yes	Inhibitor	Details
Pentagastrin	Gastrin/cholecystokinin type B receptor	Protein	Humans	Yes	Agonist	Details
Pentobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Pentostatin	Adenosine deaminase	Protein	Humans	Yes	Inhibitor	Details
Perhexiline	Carnitine O-palmitoyltransferase 1, liver isoform	Protein	Humans	Yes	Inhibitor	Details
Periciazine	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Perindopril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Perphenazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Phenacemide	Sodium channel protein type 1 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Phenacetin	Prostaglandin G/H synthase 1	Protein	Humans	Unknown	Not Available	Details
Phendimetrazine	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Agonist	Details
Phenelzine	Amine oxidase [flavin-containing] A	Protein	Humans	Yes	Antagonist	Details
Phenelzine	Amine oxidase [flavin-containing] B	Protein	Humans	Yes	Antagonist	Details
Phenindamine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Phenindione	Vitamin K epoxide reductase complex subunit 1	Protein	Humans	Yes	Inhibitor	Details
Pheniramine	Histamine H1 receptor	Protein	Humans	Yes	Inverse agonist	Details
Phenprocoumon	Vitamin K epoxide reductase complex subunit 1	Protein	Humans	Yes	Inhibitor	Details
Phenylalanine	Tyrosine 3-monooxygenase	Protein	Humans	Unknown	Binder	Details
Phenylbutazone	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Phenylephrine	Alpha-1B adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Phosphoramidon	Neprilysin	Protein	Humans	Unknown	Inhibitor	Details
Phylloquinone	Vitamin K-dependent gamma-carboxylase	Protein	Humans	Yes	Substrate Inducer Cofactor	Details
Physostigmine	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Picrotoxin	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Antagonist	Details
Pimagedine	Nitric oxide synthase, inducible	Protein	Humans	Yes	Inhibitor Downregulator	Details
Pimozide	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Pindolol	5-hydroxytryptamine receptor 1A	Protein	Humans	Unknown	Antagonist Inhibitor Ligand	Details
Pindolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Partial agonist	Details
Pindolol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Partial agonist	Details
Pipecuronium	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Pipotiazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Pirbuterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Pirenzepine	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Piretanide	Solute carrier family 12 member 1	Protein	Humans	Unknown	Inhibitor	Details
Piroxicam	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Podofilox	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Polythiazide	Solute carrier family 12 member 3	Protein	Humans	Yes	Inhibitor	Details
Potassium chloride	Solute carrier family 12 member 1	Protein	Humans	Unknown	Binder	Details
Practolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Pranlukast	Cysteinyl leukotriene receptor 1	Protein	Humans	Yes	Antagonist	Details
Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Prednisone	Glucocorticoid receptor	Protein	Humans	Yes	Agonist	Details
Prilocaine	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Primidone	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Probenecid	Solute carrier family 22 member 6	Protein	Humans	Yes	Inhibitor	Details
Procainamide	Sodium channel protein type 5 subunit alpha	Protein	Humans	Unknown	Inhibitor	Details
Procaine	5-hydroxytryptamine receptor 3A	Protein	Humans	Yes	Antagonist	Details
Procaterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Prochlorperazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Profenamine	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Progabide	Gamma-aminobutyric acid type B receptor subunit 1	Protein	Humans	Yes	Agonist	Details
Proguanil	Dihydrofolate reductase	Protein	Humans	Yes	Inhibitor	Details
Proline	Peptidyl-prolyl cis-trans isomerase A	Protein	Humans	Unknown	Binder	Details
Proline	Peptidyl-prolyl cis-trans isomerase B	Protein	Humans	Unknown	Binder	Details
Promethazine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Propafenone	Potassium voltage-gated channel subfamily H member 2	Protein	Humans	Yes	Inhibitor	Details
Propantheline	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Propiomazine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Propranolol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Propranolol	Beta-2 adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Propranolol	Beta-3 adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Propylthiouracil	Thyroid peroxidase	Protein	Humans	Yes	Inhibitor	Details
Purvalanol	Cyclin-dependent kinase 4	Protein	Humans	Unknown	Not Available	Details
Purvalanol	Mitogen-activated protein kinase 1	Protein	Humans	Unknown	Inhibitor	Details
Purvalanol	Mitogen-activated protein kinase 3	Protein	Humans	Unknown	Inhibitor	Details
Pyridostigmine	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Pyridoxal phosphate	4-aminobutyrate aminotransferase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Pyridoxal phosphate	Aspartate aminotransferase, cytoplasmic	Protein	Humans	Unknown	Activator	Details
Pyrimethamine	Dihydrofolate reductase	Protein	Humans	Yes	Inhibitor	Details
Pyruvic acid	4-aminobutyrate aminotransferase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Quinapril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Quinestrol	Estrogen receptor alpha	Protein	Humans	Yes	Agonist Modulator	Details
Quinidine	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Quinidine barbiturate	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Quinidine barbiturate	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Quinine	Intermediate conductance calcium-activated potassium channel protein 4	Protein	Humans	Unknown	Inhibitor	Details
Rabeprazole	Potassium-transporting ATPase alpha chain 1	Protein	Humans	Yes	Inhibitor	Details
Raloxifene	Estrogen receptor alpha	Protein	Humans	Yes	Agonist	Details
Raloxifene	Estrogen receptor beta	Protein	Humans	Yes	Agonist	Details
Raltitrexed	Thymidylate synthase	Protein	Humans	Yes	Inhibitor	Details
Ramelteon	Melatonin receptor type 1A	Protein	Humans	Yes	Multitarget	Details
Ramelteon	Melatonin receptor type 1B	Protein	Humans	Yes	Multitarget	Details
Ramipril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Rasagiline	Amine oxidase [flavin-containing] B	Protein	Humans	Yes	Inhibitor	Details
Rauwolfia serpentina root	Synaptic vesicular amine transporter	Protein	Humans	Yes	Inhibitor	Details
Remifentanil	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Remikiren	Renin	Protein	Humans	Yes	Inhibitor	Details
Remoxipride	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Rescinnamine	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Reserpine	Synaptic vesicular amine transporter	Protein	Humans	Yes	Inhibitor	Details
Resveratrol	Casein kinase II subunit alpha	Protein	Humans	Unknown	Not Available	Details
Resveratrol	Prostaglandin G/H synthase 1	Protein	Humans	Unknown	Inhibitor	Details
Resveratrol	Prostaglandin G/H synthase 2	Protein	Humans	Unknown	Inhibitor	Details
Reteplase	Plasminogen	Protein	Humans	Yes	Activator	Details
Ribavirin	Inosine-5'-monophosphate dehydrogenase 1	Protein	Humans	Yes	Inhibitor	Details
Ridogrel	Thromboxane A2 receptor	Protein	Humans	Yes	Antagonist	Details
Rifaximin	DNA-directed RNA polymerase subunit beta	Protein	Escherichia coli (strain K12)	Yes	Inhibitor	Details
Rimonabant	Cannabinoid receptor 1	Protein	Humans	Yes	Antagonist	Details
Risedronic acid	Farnesyl pyrophosphate synthase	Protein	Humans	Yes	Inhibitor	Details
Ritodrine	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Rituximab	B-lymphocyte antigen CD20	Protein	Humans	Yes	Antibody Regulator	Details
Rivastigmine	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Rivastigmine	Cholinesterase	Protein	Humans	Yes	Inhibitor	Details
Rizatriptan	5-hydroxytryptamine receptor 1B	Protein	Humans	Yes	Agonist	Details
Rizatriptan	5-hydroxytryptamine receptor 1D	Protein	Humans	Yes	Agonist	Details
Rizatriptan	5-hydroxytryptamine receptor 1F	Protein	Humans	Unknown	Agonist	Details
Rocuronium	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Rofecoxib	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Ropinirole	Dopamine D4 receptor	Protein	Humans	Unknown	Agonist	Details
Rosiglitazone	Peroxisome proliferator-activated receptor gamma	Protein	Humans	Yes	Agonist	Details
Rosoxacin	DNA gyrase subunit B	Protein	Escherichia coli (strain K12)	Yes	Inhibitor	Details
Rosuvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Salbutamol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Salicylic acid	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Salmeterol	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Salmon calcitonin	Calcitonin receptor	Protein	Humans	Unknown	Agonist	Details
Salsalate	Prostaglandin G/H synthase 1	Protein	Humans	Yes	Inhibitor	Details
Saprisartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Sapropterin	Tyrosine 3-monooxygenase	Protein	Humans	Yes	Cofactor	Details
Sargramostim	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	Protein	Humans	Yes	Agonist	Details
Scopolamine	Muscarinic acetylcholine receptor M2	Protein	Humans	Yes	Antagonist	Details
scyllo-inositol	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	Protein	Humans	Unknown	Inhibitor	Details
Secobarbital	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Selegiline	Amine oxidase [flavin-containing] B	Protein	Humans	Yes	Inhibitor	Details
Sermorelin	Growth hormone-releasing hormone receptor	Protein	Humans	Yes	Agonist	Details
Sertindole	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Sibutramine	Sodium-dependent noradrenaline transporter	Protein	Humans	Yes	Inhibitor	Details
Sildenafil	cGMP-specific 3',5'-cyclic phosphodiesterase	Protein	Humans	Yes	Inhibitor	Details
Simvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Protein	Humans	Yes	Inhibitor	Details
Sirolimus	Serine/threonine-protein kinase mTOR	Protein	Humans	Yes	Inhibitor	Details
Sitagliptin	Dipeptidyl peptidase 4	Protein	Humans	Yes	Inhibitor	Details
Sitaxentan	Endothelin B receptor	Protein	Humans	Unknown	Antagonist	Details
Sitaxentan	Endothelin-1 receptor	Protein	Humans	Yes	Antagonist	Details
Sodium tetradecyl sulfate	Vitamin K-dependent protein C	Protein	Humans	Yes	Inhibitor	Details
Solifenacin	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Antagonist	Details
Somatotropin	Growth hormone receptor	Protein	Humans	Yes	Ligand	Details
Sorafenib	Serine/threonine-protein kinase B-raf	Protein	Humans	Yes	Inhibitor	Details
Sorbinil	Aldose reductase	Protein	Humans	Unknown	Inhibitor	Details
Sotalol	Beta-1 adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Sparfloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Spirapril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Spironolactone	Mineralocorticoid receptor	Protein	Humans	Yes	Antagonist	Details
Streptokinase	Plasminogen	Protein	Humans	Yes	Activator	Details
SU9516	Cyclin-dependent kinase 1	Protein	Humans	Unknown	Binder	Details
SU9516	Cyclin-dependent kinase 2	Protein	Humans	Unknown	Inhibitor	Details
SU9516	Cyclin-dependent kinase 5	Protein	Humans	Unknown	Inhibitor	Details
Succinic acid	Succinate-semialdehyde dehydrogenase, mitochondrial	Protein	Humans	Unknown	Inhibitor	Details
Sufentanil	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Sulfinpyrazone	Multidrug resistance-associated protein 1	Protein	Humans	Yes	Inhibitor	Details
Sulindac	Aldose reductase	Protein	Humans	Unknown	Inhibitor	Details
Sulodexide	Antithrombin-III	Protein	Humans	Yes	Potentiator	Details
Sulpiride	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Sumatriptan	5-hydroxytryptamine receptor 1B	Protein	Humans	Yes	Agonist	Details
Sumatriptan	5-hydroxytryptamine receptor 1D	Protein	Humans	Yes	Agonist	Details
Sumatriptan	5-hydroxytryptamine receptor 1F	Protein	Humans	Yes	Agonist	Details
Sunitinib	Mast/stem cell growth factor receptor Kit	Protein	Humans	Yes	Inhibitor	Details
Sunitinib	Receptor-type tyrosine-protein kinase FLT3	Protein	Humans	Yes	Inhibitor	Details
Sunitinib	Vascular endothelial growth factor receptor 2	Protein	Humans	Yes	Inhibitor	Details
Tacrine	Acetylcholinesterase	Protein	Humans	Yes	Inhibitor	Details
Talbutal	Gamma-aminobutyric acid receptor subunit alpha-1	Protein	Humans	Yes	Potentiator	Details
Tamibarotene	Retinoic acid receptor alpha	Protein	Humans	Yes	Agonist	Details
Tamoxifen	Estrogen receptor alpha	Protein	Humans	Yes	Antagonist Agonist	Details
Tamoxifen	Estrogen receptor beta	Protein	Humans	Yes	Antagonist Agonist	Details
Tamsulosin	Alpha-1A adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Tamsulosin	Alpha-1B adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Tamsulosin	Alpha-1D adrenergic receptor	Protein	Humans	Unknown	Antagonist	Details
Tasosartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Tazarotene	Retinoic acid receptor gamma	Protein	Humans	Yes	Agonist	Details
Tegaserod	5-hydroxytryptamine receptor 4	Protein	Humans	Yes	Antagonist Partial agonist	Details
Telmisartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Temsirolimus	Serine/threonine-protein kinase mTOR	Protein	Humans	Yes	Inhibitor	Details
Tenecteplase	Plasminogen	Protein	Humans	Yes	Activator	Details
Teniposide	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Tenoxicam	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Terazosin	Alpha-1A adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Terazosin	Alpha-1B adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Terazosin	Alpha-1D adrenergic receptor	Protein	Humans	Yes	Antagonist	Details
Terbinafine	Squalene monooxygenase	Protein	Humans	No	Inhibitor	Details
Terbutaline	Beta-2 adrenergic receptor	Protein	Humans	Yes	Agonist	Details
Terfenadine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Terfenadine	Potassium voltage-gated channel subfamily H member 2	Protein	Humans	Unknown	Inhibitor	Details
Teriparatide	Parathyroid hormone/parathyroid hormone-related peptide receptor	Protein	Humans	Unknown	Ligand	Details
Terlipressin	Vasopressin V1a receptor	Protein	Humans	Yes	Agonist	Details
Testolactone	Cytochrome P450 19A1	Protein	Humans	Yes	Inhibitor	Details
Testosterone	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Testosterone cypionate	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Testosterone enanthate	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Testosterone undecanoate	Androgen receptor	Protein	Humans	Yes	Agonist	Details
Tetrabenazine	Synaptic vesicular amine transporter	Protein	Humans	Yes	Inhibitor	Details
Tetracosactide	Adrenocorticotropic hormone receptor	Protein	Humans	Yes	Agonist	Details
Tetracycline	Major prion protein	Protein	Humans	Unknown	Inhibitor	Details
Theophylline	Adenosine receptor A2b	Protein	Humans	Yes	Antagonist	Details
Theophylline	cGMP-specific 3',5'-cyclic phosphodiesterase	Protein	Humans	Yes	Inhibitor	Details
Thiabendazole	Fumarate reductase flavoprotein subunit	Protein	Escherichia coli (strain K12)	Yes	Inhibitor	Details
Thiopental	Fatty-acid amide hydrolase 1	Protein	Humans	Unknown	Inhibitor	Details
Thioproperazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Thiorphan	Neprilysin	Protein	Humans	Unknown	Inhibitor	Details
Thiothixene	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Thyrotropin alfa	Thyrotropin receptor	Protein	Humans	Yes	Agonist	Details
Tiagabine	Sodium- and chloride-dependent GABA transporter 1	Protein	Humans	Yes	Inhibitor	Details
Tiaprofenic acid	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Ticlopidine	P2Y purinoceptor 12	Protein	Humans	Yes	Antagonist	Details
Tiotropium	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Antagonist	Details
Tipranavir	Human immunodeficiency virus type 1 protease	Protein	Human immunodeficiency virus 1	Yes	Inhibitor	Details
Tirofiban	Integrin beta-3	Protein	Humans	Yes	Antagonist	Details
Tocainide	Sodium channel protein type 5 subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Tolcapone	Catechol O-methyltransferase	Protein	Humans	Yes	Inhibitor	Details
Tolmetin	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Tolrestat	Aldose reductase	Protein	Humans	Unknown	Inhibitor	Details
Tolterodine	Muscarinic acetylcholine receptor M3	Protein	Humans	Yes	Antagonist	Details
Topotecan	DNA topoisomerase 1	Protein	Humans	Yes	Inhibitor	Details
Torasemide	Solute carrier family 12 member 1	Protein	Humans	Yes	Inhibitor	Details
Torasemide	Solute carrier family 12 member 2	Protein	Humans	Yes	Inhibitor	Details
Toremifene	Estrogen receptor alpha	Protein	Humans	Yes	Modulator	Details
Tositumomab	B-lymphocyte antigen CD20	Protein	Humans	Yes	Antibody	Details
Tramadol	Mu-type opioid receptor	Protein	Humans	Yes	Agonist	Details
Tramadol	Sodium-dependent noradrenaline transporter	Protein	Humans	Yes	Inhibitor	Details
Trandolapril	Angiotensin-converting enzyme	Protein	Humans	Yes	Inhibitor	Details
Tranylcypromine	Amine oxidase [flavin-containing] A	Protein	Humans	Yes	Inhibitor	Details
Tranylcypromine	Amine oxidase [flavin-containing] B	Protein	Humans	Yes	Inhibitor	Details
Trastuzumab	Receptor tyrosine-protein kinase erbB-2	Protein	Humans	Yes	Binder Antibody	Details
Trastuzumab emtansine	Receptor tyrosine-protein kinase erbB-2	Protein	Humans	Yes	Antibody	Details
Treprostinil	Prostacyclin receptor	Protein	Humans	Yes	Agonist	Details
Tretinoin	Retinoic acid receptor gamma	Protein	Humans	Yes	Agonist	Details
Triamterene	Amiloride-sensitive sodium channel subunit alpha	Protein	Humans	Yes	Inhibitor	Details
Trichlormethiazide	Solute carrier family 12 member 3	Protein	Humans	Yes	Inhibitor	Details
Trifluoperazine	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details
Trifluoperazine	Neuron-specific vesicular protein calcyon	Protein	Humans	Yes	Antagonist	Details
Triflupromazine	5-hydroxytryptamine receptor 2B	Protein	Humans	Yes	Antagonist	Details
Trifluridine	Thymidylate synthase	Protein	Humans	Yes	Inhibitor	Details
Trihexyphenidyl	Muscarinic acetylcholine receptor M1	Protein	Humans	Yes	Antagonist	Details
Trimethadione	Voltage-dependent T-type calcium channel subunit alpha-1G	Protein	Humans	Yes	Inhibitor	Details
Trimipramine	5-hydroxytryptamine receptor 2C	Protein	Humans	Unknown	Antagonist	Details
Tripelennamine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Triprolidine	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details
Troglitazone	Peroxisome proliferator-activated receptor gamma	Protein	Humans	Yes	Agonist Regulator	Details
Tropicamide	Muscarinic acetylcholine receptor M4	Protein	Humans	Yes	Antagonist	Details
Trovafloxacin	DNA topoisomerase 2-alpha	Protein	Humans	Unknown	Inhibitor	Details
Tubocurarine	Neuronal acetylcholine receptor subunit alpha-2	Protein	Humans	Yes	Antagonist	Details
Tyrosine	Tyrosine 3-monooxygenase	Protein	Humans	Unknown	Binder	Details
Udenafil	cGMP-specific 3',5'-cyclic phosphodiesterase	Protein	Humans	Yes	Inhibitor	Details
Urofollitropin	Follicle-stimulating hormone receptor	Protein	Humans	Yes	Agonist	Details
Urokinase	Plasminogen	Protein	Humans	Yes	Activator	Details
Valdecoxib	Prostaglandin G/H synthase 2	Protein	Humans	Yes	Inhibitor	Details
Valrubicin	DNA topoisomerase 2-alpha	Protein	Humans	Yes	Inhibitor	Details
Valsartan	Type-1 angiotensin II receptor	Protein	Humans	Yes	Antagonist	Details
Vapreotide	Neurokinin 1 receptor	Protein	Humans	Unknown	Antagonist	Details
Varenicline	Neuronal acetylcholine receptor subunit alpha-4	Protein	Humans	Yes	Partial agonist	Details
Vasopressin	Vasopressin V2 receptor	Protein	Humans	Yes	Agonist Regulator	Details
Voglibose	Maltase-glucoamylase, intestinal	Protein	Humans	Yes	Inhibitor	Details
Vorinostat	Histone deacetylase 1	Protein	Humans	Yes	Inhibitor	Details
Warfarin	Vitamin K epoxide reductase complex subunit 1	Protein	Humans	Yes	Inhibitor	Details
Ximelagatran	Prothrombin	Protein	Humans	Yes	Inhibitor	Details
Zafirlukast	Cysteinyl leukotriene receptor 1	Protein	Humans	Yes	Antagonist	Details
Zanamivir	Neuraminidase	Protein	Influenza A virus (strain A/Bangkok/1/1979 H3N2)	Yes	Inhibitor	Details
Zileuton	Arachidonate 5-lipoxygenase	Protein	Humans	Yes	Inhibitor	Details
Zoledronic acid	Farnesyl pyrophosphate synthase	Protein	Humans	Yes	Inhibitor	Details
Zuclopenthixol	Dopamine D2 receptor	Protein	Humans	Yes	Antagonist	Details

Drug Enzymes

Drug	Enzyme	Kind	Organism	Pharmacological Action	Actions
Entacapone	Catechol O-methyltransferase	Protein	Humans	Unknown	Inhibitor	Details
Menadione	Aldehyde oxidase	Protein	Humans	Unknown	Inhibitor	Details
Moclobemide	Amine oxidase [flavin-containing] A	Protein	Humans	Unknown	Inhibitor	Details
Phenelzine	Amine oxidase [flavin-containing] B	Protein	Humans	Unknown	Substrate	Details
Tryptophan	Indoleamine 2,3-dioxygenase 1	Protein	Humans	Unknown	Substrate	Details

Drug Carriers

Drug	Carrier	Kind	Organism	Pharmacological Action	Actions
Alclometasone	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Beclomethasone dipropionate	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Bismuth subsalicylate	Serum albumin	Protein	Humans	No	Binder	Details
Ciclesonide	Corticosteroid-binding globulin	Protein	Humans	No	Binder	Details
Flumethasone	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Fluocinolone acetonide	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Fluocinonide	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Flurandrenolide	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Gadobenic acid	Serum albumin	Protein	Humans	No	Binder	Details
Iodipamide	Serum albumin	Protein	Humans	Unknown	Binder	Details
Paramethasone	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Prednisolone	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Prednisolone acetate	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Rimexolone	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details
Sodium lauryl sulfate	Serum albumin	Protein	Humans	Unknown	Binder	Details
Triamcinolone	Corticosteroid-binding globulin	Protein	Humans	Unknown	Binder	Details

Drug Transporters

Drug	Transporter	Kind	Organism	Pharmacological Action	Actions
Potassium chloride	Solute carrier family 12 member 1	Protein	Humans	Unknown	Substrate	Details