| DB00449 | Dipivefrin | approved | yes | agonist | Details |
| DB00484 | Brimonidine | approved | yes | agonist | Details |
| DB00575 | Clonidine | approved | yes | agonist | Details |
| DB00629 | Guanabenz | approved, investigational | yes | agonist | Details |
| DB00633 | Dexmedetomidine | approved, vet_approved | yes | agonist | Details |
| DB00865 | Benzphetamine | approved, illicit | yes | agonist | Details |
| DB00964 | Apraclonidine | approved | yes | agonist | Details |
| DB00968 | Methyldopa | approved | yes | agonist | Details |
| DB01018 | Guanfacine | approved, investigational | yes | agonist | Details |
| DB00370 | Mirtazapine | approved | yes | antagonist | Details |
| DB00656 | Trazodone | approved, investigational | no | antagonist | Details |
| DB00800 | Fenoldopam | approved | unknown | antagonist | Details |
| DB00852 | Pseudoephedrine | approved | yes | agonist | Details |
| DB00935 | Oxymetazoline | approved, investigational | yes | agonistpartial agonist | Details |
| DB01392 | Yohimbine | approved, investigational, vet_approved | yes | antagonist | Details |
| DB00321 | Amitriptyline | approved | no | antagonistagonist | Details |
| DB01472 | 4-Methoxyamphetamine | experimental, illicit | yes | agonist | Details |
| DB00368 | Norepinephrine | approved | yes | agonist | Details |
| DB00696 | Ergotamine | approved | unknown | partial agonist | Details |
| DB04855 | Dronedarone | approved | yes | antagonist | Details |
| DB00751 | Epinastine | approved, investigational | unknown | unknown | Details |
| DB06148 | Mianserin | approved, investigational | unknown | antagonist | Details |
| DB04948 | Lofexidine | approved, investigational | yes | agonist | Details |
| DB05492 | Epicept NP-1 | investigational | unknown | | Details |
| DB06262 | Droxidopa | approved, investigational | yes | agonist | Details |
| DB06216 | Asenapine | approved | unknown | antagonist | Details |
| DB06229 | Ocaperidone | investigational | unknown | | Details |
| DB06623 | Flupirtine | investigational | unknown | | Details |
| DB06694 | Xylometazoline | approved, investigational | yes | agonist | Details |
| DB01200 | Bromocriptine | approved, investigational, withdrawn | unknown | agonist | Details |
| DB00589 | Lisuride | approved, investigational | unknown | other/unknown | Details |
| DB00248 | Cabergoline | approved | unknown | antagonist | Details |
| DB00413 | Pramipexole | approved, investigational | unknown | agonist | Details |
| DB00714 | Apomorphine | approved, investigational | unknown | agonist | Details |
| DB01267 | Paliperidone | approved | unknown | antagonist | Details |
| DB01224 | Quetiapine | approved | unknown | antagonist | Details |
| DB00246 | Ziprasidone | approved | unknown | antagonist | Details |
| DB00363 | Clozapine | approved | unknown | antagonist | Details |
| DB01238 | Aripiprazole | approved, investigational | no | antagonist | Details |
| DB01403 | Methotrimeprazine | approved, investigational | unknown | antagonist | Details |
| DB01608 | Periciazine | approved, investigational | yes | antagonist | Details |
| DB01624 | Zuclopenthixol | approved, investigational | unknown | antagonist | Details |
| DB01149 | Nefazodone | approved, withdrawn | unknown | antagonist | Details |
| DB00543 | Amoxapine | approved | unknown | antagonist | Details |
| DB00797 | Tolazoline | approved, vet_approved | unknown | antagonist | Details |
| DB00320 | Dihydroergotamine | approved, investigational | unknown | agonist | Details |
| DB06711 | Naphazoline | approved, investigational | yes | agonist | Details |
| DB00925 | Phenoxybenzamine | approved | yes | antagonist | Details |
| DB01363 | Ephedra sinica root | nutraceutical | yes | agonist | Details |
| DB01577 | Metamfetamine | approved, illicit, withdrawn | yes | agonist | Details |
| DB00668 | Epinephrine | approved, vet_approved | yes | agonist | Details |
| DB08815 | Lurasidone | approved, investigational | unknown | | Details |
| DB00408 | Loxapine | approved | unknown | binder | Details |
| DB01136 | Carvedilol | approved, investigational | unknown | antagonist | Details |
| DB00726 | Trimipramine | approved | unknown | antagonist | Details |
| DB00457 | Prazosin | approved | unknown | binder | Details |
| DB09242 | Moxonidine | approved, investigational | yes | agonist | Details |
| DB11738 | Rilmenidine | approved, investigational | unknown | | Details |
| DB00555 | Lamotrigine | approved, investigational | unknown | inhibitor | Details |
| DB09244 | Pirlindole | experimental | unknown | antagonist | Details |
| DB09286 | Pipamperone | investigational | unknown | antagonist | Details |
| DB11124 | Racepinephrine | approved | yes | agonist | Details |
| DB06153 | Pizotifen | approved | unknown | antagonist | Details |
| DB11278 | DL-Methylephedrine | approved | yes | agonist | Details |
| DB04846 | Celiprolol | approved, investigational | unknown | antagonist | Details |
| DB14185 | Aripiprazole lauroxil | approved, investigational | no | | Details |
| DB00502 | Haloperidol | approved | unknown | | Details |