| DB00283 | Clemastine | approved, investigational | yes | antagonist | Details |
| DB00341 | Cetirizine | approved | yes | antagonist | Details |
| DB00342 | Terfenadine | approved, withdrawn | yes | antagonist | Details |
| DB00354 | Buclizine | approved | yes | antagonist | Details |
| DB00366 | Doxylamine | approved, vet_approved | yes | antagonist | Details |
| DB00405 | Dexbrompheniramine | approved | yes | antagonist | Details |
| DB00427 | Triprolidine | approved | yes | antagonist | Details |
| DB00455 | Loratadine | approved, investigational | yes | antagonist | Details |
| DB00557 | Hydroxyzine | approved | yes | inverse agonist | Details |
| DB00568 | Cinnarizine | approved, investigational | yes | antagonist | Details |
| DB00637 | Astemizole | approved, withdrawn | yes | antagonist | Details |
| DB05381 | Histamine | approved, investigational | yes | agonist | Details |
| DB00719 | Azatadine | approved | yes | antagonist | Details |
| DB00737 | Meclizine | approved | yes | antagonist | Details |
| DB00748 | Carbinoxamine | approved | yes | antagonist | Details |
| DB00768 | Olopatadine | approved | yes | antagonist | Details |
| DB00792 | Tripelennamine | approved, vet_approved | yes | antagonist | Details |
| DB00835 | Brompheniramine | approved | yes | antagonist | Details |
| DB00902 | Methdilazine | approved | yes | antagonist | Details |
| DB00934 | Maprotiline | approved, investigational | no | antagonist | Details |
| DB00950 | Fexofenadine | approved, investigational | yes | antagonist | Details |
| DB00967 | Desloratadine | approved, investigational | yes | antagonist | Details |
| DB00972 | Azelastine | approved | yes | antagonist | Details |
| DB00985 | Dimenhydrinate | approved | yes | antagonist | Details |
| DB01071 | Mequitazine | experimental | yes | antagonist | Details |
| DB01075 | Diphenhydramine | approved, investigational | yes | antagonist | Details |
| DB01084 | Emedastine | approved | yes | antagonist | Details |
| DB01114 | Chlorpheniramine | approved | yes | antagonist | Details |
| DB01146 | Diphenylpyraline | approved, investigational | yes | antagonist | Details |
| DB01176 | Cyclizine | approved | yes | antagonist | Details |
| DB01237 | Bromodiphenhydramine | approved | yes | antagonist | Details |
| DB01246 | Alimemazine | approved, vet_approved | yes | antagonist | Details |
| DB00246 | Ziprasidone | approved | unknown | antagonist | Details |
| DB00334 | Olanzapine | approved, investigational | unknown | antagonist | Details |
| DB00363 | Clozapine | approved | unknown | antagonist | Details |
| DB00420 | Promazine | approved, vet_approved | unknown | antagonist | Details |
| DB00656 | Trazodone | approved, investigational | unknown | antagonist | Details |
| DB00767 | Benzquinamide | withdrawn | yes | antagonist | Details |
| DB00777 | Propiomazine | approved | yes | antagonist | Details |
| DB00920 | Ketotifen | approved | yes | antagonist | Details |
| DB01069 | Promethazine | approved, investigational | yes | antagonist | Details |
| DB01106 | Levocabastine | approved, investigational | yes | antagonist | Details |
| DB01142 | Doxepin | approved, investigational | yes | antagonist | Details |
| DB01151 | Desipramine | approved, investigational | no | antagonist | Details |
| DB01173 | Orphenadrine | approved | yes | antagonist | Details |
| DB01403 | Methotrimeprazine | approved, investigational | unknown | antagonist | Details |
| DB01619 | Phenindamine | approved | yes | antagonist | Details |
| DB01620 | Pheniramine | approved | yes | inverse agonist | Details |
| DB04837 | Clofedanol | approved, withdrawn | yes | antagonist | Details |
| DB04841 | Flunarizine | approved | unknown | antagonist | Details |
| DB01615 | Aceprometazine | experimental | yes | antagonist | Details |
| DB01239 | Chlorprothixene | approved, experimental, investigational, withdrawn | yes | antagonist | Details |
| DB00370 | Mirtazapine | approved | no | antagonist | Details |
| DB01224 | Quetiapine | approved | unknown | antagonist | Details |
| DB00434 | Cyproheptadine | approved | yes | antagonist | Details |
| DB04890 | Bepotastine | approved | yes | antagonist | Details |
| DB00751 | Epinastine | approved, investigational | yes | antagonist | Details |
| DB06148 | Mianserin | approved, investigational | unknown | antagonist | Details |
| DB04905 | Tesmilifene | investigational | unknown | antagonist | Details |
| DB05079 | HY10275 | investigational | unknown | | Details |
| DB05345 | SO-101 | investigational | unknown | | Details |
| DB05080 | OBE101 | investigational | unknown | | Details |
| DB05492 | Epicept NP-1 | investigational | unknown | | Details |
| DB06216 | Asenapine | approved | unknown | antagonist | Details |
| DB06229 | Ocaperidone | investigational | unknown | | Details |
| DB00245 | Benzatropine | approved | unknown | antagonist | Details |
| DB01267 | Paliperidone | approved | unknown | antagonist | Details |
| DB01238 | Aripiprazole | approved, investigational | no | antagonist | Details |
| DB00321 | Amitriptyline | approved | no | antagonist | Details |
| DB00458 | Imipramine | approved | no | antagonist | Details |
| DB00540 | Nortriptyline | approved | no | antagonist | Details |
| DB01175 | Escitalopram | approved | unknown | inhibitor | Details |
| DB00726 | Trimipramine | approved | unknown | antagonist | Details |
| DB00797 | Tolazoline | approved, vet_approved | unknown | agonist | Details |
| DB06766 | Alcaftadine | approved | unknown | antagonist | Details |
| DB08799 | Antazoline | approved | yes | antagonist | Details |
| DB08800 | Chloropyramine | experimental | yes | antagonist | Details |
| DB08801 | Dimetindene | approved, investigational | yes | antagonist | Details |
| DB08802 | Isothipendyl | experimental | yes | antagonist | Details |
| DB06698 | Betahistine | approved, investigational | yes | agonist | Details |
| DB06691 | Mepyramine | approved, vet_approved | yes | antagonist | Details |
| DB00477 | Chlorpromazine | approved, investigational, vet_approved | yes | antagonist | Details |
| DB04946 | Iloperidone | approved | unknown | antagonist | Details |
| DB00215 | Citalopram | approved | no | binder | Details |
| DB01624 | Zuclopenthixol | approved, investigational | unknown | antagonist | Details |
| DB08936 | Chlorcyclizine | approved | yes | antagonist | Details |
| DB00408 | Loxapine | approved | unknown | binder | Details |
| DB00543 | Amoxapine | approved | unknown | antagonist | Details |
| DB09016 | Butriptyline | approved, withdrawn | yes | antagonist | Details |
| DB06678 | Esmirtazapine | investigational | unknown | inverse agonist | Details |
| DB06282 | Levocetirizine | approved | yes | antagonistinhibitor | Details |
| DB11591 | Bilastine | approved, investigational | yes | antagonist | Details |
| DB09488 | Acrivastine | approved | yes | antagonist | Details |
| DB09555 | Dexchlorpheniramine maleate | approved | yes | antagonist | Details |
| DB08922 | Perospirone | experimental | unknown | inverse agonist | Details |
| DB09167 | Dosulepin | approved | yes | antagonist | Details |
| DB11614 | Rupatadine | approved | yes | antagonist | Details |
| DB09195 | Lorpiprazole | approved | yes | antagonist | Details |
| DB00555 | Lamotrigine | approved, investigational | unknown | antagonist | Details |
| DB06153 | Pizotifen | approved | unknown | antagonist | Details |
| DB11235 | Thonzylamine | approved | yes | antagonist | Details |
| DB14185 | Aripiprazole lauroxil | approved, investigational | no | antagonist | Details |
| DB00433 | Prochlorperazine | approved, vet_approved | unknown | antagonist | Details |
| DB00502 | Haloperidol | approved | unknown | | Details |
| DB00715 | Paroxetine | approved, investigational | unknown | inhibitor | Details |
| DB00734 | Risperidone | approved, investigational | unknown | antagonist | Details |
| DB06016 | Cariprazine | approved, investigational | unknown | antagonist | Details |
| DB00912 | Repaglinide | approved, investigational | yes | antagonist | Details |
| DB09185 | Viloxazine | approved, investigational, withdrawn | unknown | antagonist | Details |
| DB09128 | Brexpiprazole | approved, investigational | unknown | antagonist | Details |