| DB04795 | Thenoyltrifluoroacetone | experimental | unknown | | Details |
| DB02161 | Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester | experimental | unknown | | Details |
| DB03721 | N-acetyl-alpha-neuraminic acid | experimental | unknown | | Details |
| DB06442 | Avasimibe | investigational | unknown | | Details |
| DB01101 | Capecitabine | approved, investigational | no | substrate | Details |
| DB00762 | Irinotecan | approved, investigational | unknown | substrate | Details |
| DB00675 | Tamoxifen | approved | unknown | inhibitor | Details |
| DB00328 | Indomethacin | approved, investigational | unknown | substrate | Details |
| DB06693 | Mevastatin | experimental | unknown | inhibitor | Details |
| DB03056 | 4-Piperidino-Piperidine | experimental | unknown | | Details |
| DB02659 | Cholic Acid | approved | unknown | | Details |
| DB07821 | (1R)-1,2,2-trimethylpropyl (R)-methylphosphinate | experimental | unknown | | Details |
| DB08224 | (1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL | experimental | unknown | | Details |
| DB01410 | Ciclesonide | approved, investigational | unknown | substrate | Details |
| DB00583 | Levocarnitine | approved, investigational | unknown | | Details |
| DB04838 | Cyclandelate | approved | unknown | | Details |
| DB01599 | Probucol | approved, investigational | unknown | | Details |
| DB01086 | Benzocaine | approved, investigational | unknown | inhibitor | Details |
| DB00519 | Trandolapril | approved | unknown | substrate | Details |
| DB06201 | Rufinamide | approved | unknown | substrate | Details |
| DB06695 | Dabigatran etexilate | approved | unknown | substrate | Details |
| DB00758 | Clopidogrel | approved | no | substrate | Details |
| DB00688 | Mycophenolate mofetil | approved, investigational | unknown | substrate | Details |
| DB11362 | Selexipag | approved | no | substrate | Details |
| DB09269 | Phenylacetic acid | approved | unknown | substrate | Details |
| DB00454 | Meperidine | approved | unknown | | Details |
| DB00647 | Dextropropoxyphene | approved, illicit, investigational, withdrawn | unknown | | Details |
| DB01183 | Naloxone | approved, vet_approved | unknown | binder | Details |
| DB00382 | Tacrine | approved, investigational, withdrawn | unknown | | Details |
| DB00907 | Cocaine | approved, illicit | unknown | binder | Details |
| DB01452 | Diamorphine | approved, illicit, investigational | unknown | | Details |
| DB09342 | Propoxycaine | approved | unknown | substrate | Details |
| DB11181 | Homatropine | approved | unknown | substrate | Details |
| DB09299 | Tenofovir alafenamide | approved | no | substrate | Details |
| DB00198 | Oseltamivir | approved | yes | substrate | Details |
| DB00881 | Quinapril | approved, investigational | unknown | substrate | Details |
| DB01039 | Fenofibrate | approved | unknown | substrate | Details |
| DB00907 | Cocaine | approved, illicit | unknown | substrate | Details |
| DB12404 | Remimazolam | approved, investigational | unknown | substrate | Details |
| DB14845 | Filgotinib | approved, investigational | unknown | metabolizer | Details |
| DB14761 | Remdesivir | approved, investigational | yes | substrate | Details |
| DB00875 | Flupentixol | approved, investigational, withdrawn | no | inhibitor | Details |
| DB16349 | Vicagrel | investigational | unknown | substrate | Details |
| DB09061 | Cannabidiol | approved, investigational | no | inhibitor | Details |
| DB00470 | Dronabinol | approved, illicit | no | inhibitor | Details |
| DB14737 | Cannabinol | experimental, investigational | unknown | inhibitor | Details |
| DB14009 | Medical Cannabis | experimental, investigational | unknown | inhibitor | Details |
| DB00641 | Simvastatin | approved | unknown | inhibitor | Details |
| DB12095 | Telotristat ethyl | approved, investigational | no | substrate | Details |