Identification
- Summary
Isopropyl alcohol is an antiseptic and disinfectant used in a variety of clinical and domestic settings.
- Brand Names
- Adrenalin, Avonex, Benefix, Cyltezo, Duraprep, Elevidys, Humira, Kenalog, Lupaneta Pack 1-month, Lupron, Marbeta, Meijer, P-Care M, P-Care MG, P-care, P-care X, Venipuncture Px1, Xyntha, Zolgensma Kit 2.6 - 3.0 Kg
- Generic Name
- Isopropyl alcohol
- DrugBank Accession Number
- DB02325
- Background
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Structure
Structure for Isopropyl alcohol (DB02325)
- Weight
- Average: 60.095
Monoisotopic: 60.057514878 - Chemical Formula
- C3H8O
- Synonyms
- 2-Propanol
- Alcohol isopropílico
- Isopropanol
- Isopropyl alcohol
- External IDs
- FEMA NO. 2929
- NSC-135801
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to prevent Infection Combination Product in combination with: Iodine (DB05382) •••••••••••• •••••••• Used as adjunct in combination for therapy Infection Combination Product in combination with: Iodine (DB05382) •••••••••••• •••••••• Prophylaxis of Infection ••• ••• - Associated Therapies
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- International/Other Brands
- Isopro
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 1 Hotel Hand Sanitizer Gel 100 mL/100mL Topical PhytogenX, Inc. 2020-08-24 Not applicable US 
1000 Wet Wipes Cloth 2825 g/10001 Topical JIANGSU MEIFAN BIOTECHNOLOGY CO., LTD. 2020-11-11 Not applicable US 1000 Wet Wipes Cloth 2.82 kg/10001 Topical JIANGSU MEIFAN BIOTECHNOLOGY CO., LTD. 2020-11-09 Not applicable US 108 Hand Sanitizer Liquid 75 mL/100mL Topical JAMESTOWN PAINT COMPANY 2020-03-30 Not applicable US 16oz Isopropyl Alcohol Liquid 70 mL/70mL Topical Collective Science Integration 2020-09-24 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 25 Person ANSI Isopropyl alcohol (70 mL/100mL) + Acetaminophen (325 mg/1) + Acetylsalicylic acid (325 mg/1) + Bacitracin zinc (400 [iU]/1g) + Benzalkonium chloride (0.13 g/100g) + Benzalkonium chloride (0.40 mL/100mL) + Benzocaine (6 mL/100mL) + Ethanol (60 mL/100mL) + Ethanol (62 g/100g) + Ibuprofen (200 mg/1) + Lidocaine (0.5 g/100g) + Neomycin sulfate (5 mg/1g) + Polymyxin B sulfate (5000 [iU]/1g) + Water (98.6 mL/100mL) Kit Ophthalmic; Oral; Topical Genuine First Aid 2010-04-25 Not applicable US 3M DuraPrep Surgical Isopropyl alcohol (636.4 mg/1mL) + Iodine povacrylex (6.02 mg/1mL) Solution Topical 3M Company 2006-09-29 Not applicable US 3M DURAPREP® SURGICAL SOLUTION Isopropyl alcohol (60.61 % v/v) + Iodine (0.12 % v/v) Solution Topical 3M COLOMBIA S.A. 2006-11-10 2015-08-03 Colombia 
3M SoluPrep Isopropyl alcohol (0.7 mL/1mL) + Chlorhexidine gluconate (20 mg/1mL) Solution Topical 3M Company 2018-10-08 2020-09-30 US 3M SoluPrep Isopropyl alcohol (0.7 mL/1mL) + Chlorhexidine gluconate (20 mg/1mL) Solution Topical 3M Company 2018-10-08 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 4047 Fist Aid Kit Isopropyl alcohol (0.7 mL/1mL) + Ethanol (0.5 mL/1mL) + Lidocaine hydrochloride (20 mg/1mL) Kit Topical Honeywell Safety Products USA, Inc 2018-11-24 2019-10-18 US 4048 Fist Aid Kit Isopropyl alcohol (0.7 mL/1mL) + Ethanol (0.5 mL/1mL) + Lidocaine hydrochloride (20 mg/1mL) Kit Topical Honeywell Safety Products USA, Inc 2018-11-24 2019-10-18 US 4051 First Aid Kit Isopropyl alcohol (0.7 mL/1mL) + Benzalkonium chloride (0.13 g/100g) + Ethanol (0.5 mL/1mL) + Lidocaine hydrochloride (0.5 g/100g) + Lidocaine hydrochloride (20 mg/1mL) + Neomycin sulfate (3.5 mg/1g) Kit Topical Honeywell Safety Products USA, Inc 2018-11-21 2019-10-18 US 4052 First Aid Kit Isopropyl alcohol (0.7 mL/1mL) + Benzalkonium chloride (0.13 g/100g) + Ethanol (0.5 mL/1mL) + Lidocaine hydrochloride (0.5 g/100g) + Lidocaine hydrochloride (20 mg/1mL) + Neomycin sulfate (3.5 mg/1g) Kit Topical Honeywell Safety Products USA, Inc 2018-11-21 2019-10-18 US 4072First Aid Kit Isopropyl alcohol (0.7 mL/1mL) Kit Topical Honeywell Safety Products USA, Inc 2018-11-06 Not applicable US
Categories
- ATC Codes
- D08AX05 — Isopropanol
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as secondary alcohols. These are compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R') (R,R'=alkyl, aryl).
- Kingdom
- Organic compounds
- Super Class
- Organic oxygen compounds
- Class
- Organooxygen compounds
- Sub Class
- Alcohols and polyols
- Direct Parent
- Secondary alcohols
- Alternative Parents
- Hydrocarbon derivatives
- Substituents
- Aliphatic acyclic compound / Hydrocarbon derivative / Secondary alcohol
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- secondary alcohol (CHEBI:17824) / a small molecule (ISO-PROPANOL)
- Affected organisms
- Humans and other mammals
Chemical Identifiers
- UNII
- ND2M416302
- CAS number
- 67-63-0
- InChI Key
- KFZMGEQAYNKOFK-UHFFFAOYSA-N
- InChI
- InChI=1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
- IUPAC Name
- propan-2-ol
- SMILES
- CC(C)O
References
- Synthesis Reference
http://en.wikipedia.org/wiki/Alcohol#Laboratory_synthesis
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0000863
- KEGG Drug
- D00137
- KEGG Compound
- C01845
- PubChem Compound
- 3776
- PubChem Substance
- 46508136
- ChemSpider
- 3644
- 797541
- ChEBI
- 17824
- ChEMBL
- CHEMBL582
- ZINC
- ZINC000000901159
- PharmGKB
- PA450117
- PDBe Ligand
- IPA
- Wikipedia
- Isopropyl_alcohol
- PDB Entries
- 1ak9 / 1am7 / 1aqn / 1asw / 1au9 / 1bnd / 1bw9 / 1c1d / 1c1x / 1ci8 … show 734 more
- MSDS
- Download (51.8 KB)
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count 4 Active Not Recruiting Treatment Closed Lower Extremity Fracture / Fracture of Pelvis (Disorder) / Open Appendicular Fracture / Surgical Site Infections / Unplanned Fracture-Related Reoperation 1 4 Active Not Recruiting Treatment Psoriasis / Psoriasis Vulgaris (Plaque Psoriasis) 1 4 Completed Not Available Antimicrobial Effectiveness 1 4 Completed Not Available Healthy Subjects (HS) 1 4 Completed Not Available Hip Arthroplasty 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- B. Braun Melsungen AG
- Derm Buro Inc.
- Medical Components Inc.
- Medical Techniques LLC
- Smiths Medical ASD Inc.
- Dosage Forms
Form Route Strength Cloth Topical 2.82 kg/10001 Cloth Topical 2825 g/10001 Liquid Topical 70 mL/70mL Cloth Topical 0.594 kg/2001 Cloth Topical 1130 g/4001 Kit Topical 0.7 mL/1mL Cream; kit; swab Topical Kit Respiratory (inhalation); Topical Cream; kit; liquid; ointment; swab Ophthalmic; Topical Gel; kit; liquid; swab Topical Cream; kit; liquid; ointment; swab Topical Kit; swab Topical 0.7 mL/1mL Kit Ophthalmic; Oral; Respiratory (inhalation); Topical Cream; kit; liquid; ointment; swab; tablet Ophthalmic; Oral; Topical Kit; liquid; ointment; spray; swab; tablet Ophthalmic; Oral; Topical Kit; liquid; lozenge; ointment; spray; swab; tablet Ophthalmic; Oral; Topical Gel; kit; liquid; ointment; swab Ophthalmic; Topical Kit Ophthalmic; Respiratory (inhalation); Topical Cream; inhalant; kit; swab; tablet Oral; Respiratory (inhalation); Topical Kit Oral; Respiratory (inhalation); Topical Gel; kit; swab Topical Cream; kit; liquid; swab Ophthalmic; Topical Inhalant; kit; liquid; ointment; spray; swab Ophthalmic; Respiratory (inhalation); Topical Cream; kit; liquid; ointment; swab; tablet Oral; Topical Inhalant; kit; liquid; ointment; spray; swab; tablet Ophthalmic; Oral; Respiratory (inhalation); Topical Cream; kit; ointment; swab Topical Kit; liquid; ointment; swab; tablet Ophthalmic; Oral; Topical Gel; kit; liquid; ointment; solution; swab Ophthalmic; Topical Kit; liquid; ointment; swab Topical Gel; kit; liquid; swab Ophthalmic; Topical Kit; liquid; swab Ophthalmic; Topical Kit; liquid; ointment; spray; swab Ophthalmic; Topical Kit; liquid; ointment; swab Ophthalmic; Topical Kit; liquid; ointment; swab; tablet Oral; Topical Cream; gel; kit; liquid; ointment; spray; swab Ophthalmic; Topical Cream; kit; liquid; ointment; spray; swab Ophthalmic; Topical Gel; kit; liquid; ointment; swab; tablet Oral; Topical Kit Irrigation; Ophthalmic; Respiratory (inhalation); Topical Cream; irrigant; kit; liquid; ointment; swab Irrigation; Ophthalmic; Topical Irrigant; kit; liquid; swab Irrigation; Ophthalmic; Topical Kit Irrigation; Oral; Respiratory (inhalation); Topical Kit Irrigation; Ophthalmic; Oral; Respiratory (inhalation); Topical Solution Topical 500 mg/1mL Cloth Topical 1.07 mL/1 Liquid Topical 70 g/100mL Spray Topical 700 mg/1mL Solution Topical 1 mL/700mg Solution Topical 44.4 mL/60mL Cloth Topical 3.15 mL/1 Solution Topical 999 mL/1000mL Cream Topical Injection, solution; kit Infiltration; Intramuscular; Intravenous; Perineural; Topical Injection, solution; kit Infiltration; Intramuscular; Perineural; Topical Injection, solution; kit Intramuscular; Intravenous; Topical Cloth Topical 1 mL/100mL Spray Topical 0.6 mL/1mL Kit Intramuscular; Intraocular; Subcutaneous Lotion Topical 0.7575 g/1mL Solution Topical 70 mL/100mL Liquid Topical 62.0 % Gel Topical 62 mL/100mL Liquid Topical 0.99 mL/1mL Liquid Topical 60 mg/1mL Patch Topical 700 mg/1g Swab Topical .70 g/1g Swab Topical 7 mL/10mL Solution Topical 70.7 mL Cloth Topical 70 g/100g Swab Topical 700 mg/1g Gel Topical 700 mL/1000mL Swab Topical 0.7 1/1 Swab Topical 0.70 mL/1 Swab Topical 70 mL/1 Cloth Topical 0.7 mL/0.7mL Cloth Topical 700 mg/1mL Swab Topical 70 1/1 Cloth Topical 0.70 mL/1mL Cloth Topical 70 g/1001 Liquid Topical 70 mL/100mL Sponge Topical 7 mL/10mL Swab Topical .70 mg/1mg Swab Topical 0.28 mL/0.4mL Swab Topical 0.56 mL/0.8mL Swab Topical 0.7 mL/1mL Swab Topical 0.7 mL/1 Swab Topical 0.8 g/0.8g Swab Topical 700 mg/1 Swab Topical 8 g/1 Swab Topical Cloth Topical 70 mg/1 Swab Extracorporeal; Topical 75 g/100g Liquid Topical 70 g/100g Cloth Topical 0.7 mL/1g Liquid Topical 70 % Swab Topical 1.4 mL/1 Swab Topical 70 mL/1g Swab Topical .70 mL/1 Swab Topical 0.70 g/1mL Cloth Extracorporeal 720 mL/2001 Gel Topical 70 % Lotion Topical 70 % Liquid Topical 21 mL / 30 mL Lotion Topical 75 mL/100mL Liquid Topical 76 mL/100mL Liquid Topical 760 g/1000mL Spray Topical 700 mg/1000mL Jelly Topical 50 % Injection, emulsion; kit Intravenous; Topical Gel Topical 2142.88 g/3380.08g Cloth Topical 1.4798 g/1.4798g Liquid Topical 0.56118 g/1mL Liquid Topical 715 mL/1L Liquid Topical 7000 L/10000L Liquid Topical 8000 L/10000L Gel Topical 70 mL/100mL Spray Topical 80 mL/100mL Solution / drops Auricular (otic) Kit Topical 70 mL/100mL Gel Topical 43 mL/60mL Patch Topical .70 mL/1mL Gel Topical 70 L/1L Kit Intramuscular Spray Topical 70 mL/60mL Injection, solution; kit Intramuscular; Topical Gel Topical 100 mL/100mL Solution Topical 2076.54 g/3292.22g Liquid Topical 30 mg/30mL Swab Topical 70 % Injection, powder, lyophilized, for solution; kit Intravenous; Topical Kit Infiltration; Intra-articular; Intralesional; Intramuscular; Perineural; Topical Gel Topical 0.07 mL/1mL Spray Topical 0.75 mL/1mL Liquid Topical 0.7 L/1L Kit Epidural; Infiltration; Topical Gel Topical 754 mL/1000mL Solution, gel forming, extended release Topical Cloth; injection, solution; kit; solution Epidural; Infiltration; Intra-articular; Intramuscular; Topical Kit Electro-osmosis Liquid Topical 60 % Liquid Topical 63 % Gel Topical 94.8 mL/99mL Cloth; kit; ointment; swab Topical Gel Topical 2.8 L/4L Liquid Topical 0.754 L/1L Gel Topical 60 mL/100mL Gel Topical 700 mg/1mL Spray Topical 42 mL/1 Gel Topical 0.8 L/1L Gel Topical 0.7 L/1L Spray Topical 45 mL/60mL Gel Extracorporeal Gel Topical 70 um/60mL Liquid Topical 70 mg/100mg Injection, solution; injection, suspension; kit Epidural; Intra-articular; Intracaudal; Intramuscular; Intravenous; Perineural; Topical Gel Topical 75 L/100L Liquid Topical 0.75 mL/1mL Liquid Topical 91 mL/100mL Liquid Auricular (otic) 950 mg/1mL Cloth Topical 0.7 g/1g Kit Oral Patch Topical 70 mL/100mL Swab Oral Injection, solution; kit; solution Epidural; Infiltration; Intracaudal; Perineural; Topical Liquid Auricular (otic) 95 mL/100mL Spray Topical 91 mL/100mL Swab Topical 70 g/100g Solution Cutaneous Kit Infiltration; Intramuscular; Intravenous; Topical Kit Epidural; Infiltration; Intramuscular; Intravenous; Topical Liquid Extracorporeal Liquid Topical 50 mL/100mL Kit Intramuscular; Intravenous; Topical Solution Topical 660 mL/943mL Liquid Auricular (otic) 0.76 g/1mL Swab Topical 0.7 g/1mL Cloth Topical 70 % Kit Intra-articular; Intralesional; Intramuscular; Soft tissue; Topical Kit Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular; Intravenous; Soft tissue; Subcutaneous; Topical Kit Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular; Soft tissue; Topical Liquid Auricular (otic) 94.998 1/100mL Liquid Auricular (otic) Liquid Auricular (otic) 94.998 g/100mL Liquid Auricular (otic) 95 g/100mL Solution Topical 80 mL/100mL Gel Topical 177.75 mL/237mL Spray Topical 177.75 mL/237mL Swab Topical 70 mL/1001 Kit Intravenous Liquid Auricular (otic) 0.95 g/100g Gel Topical 62 g/100mL Gel Topical 65.5 g/100mL Solution Topical 89.4 mL/100mL Injection; kit; swab Intramuscular; Subcutaneous; Topical Kit Intramuscular; Subcutaneous Injection; kit Intramuscular; Subcutaneous; Topical Liquid Topical .70 L/100L Gel Topical 73 mL/100mL Cloth Topical 0.34 g/1 Liquid Topical 0.72 mL/1mL Liquid Topical 2838 mL/3780mL Cloth Topical 0.70 1/1 Kit Ophthalmic; Topical Injection, solution; kit Infiltration; Perineural; Topical Injection, solution; kit Perineural; Retrobulbar; Topical Liquid Topical 13 g/100g Aerosol, foam Topical Solution Topical 0.14 g/0.2mL Solution Topical 1.4 g/2mL Liquid Topical 28.66 mL/29mL Patch Topical 70 g/100g Patch Topical Swab Topical 75 g/100g Kit Oral; Topical Solution Solution Topical 700 g/1000g Gel Topical 70 L/100L Solution Topical 75 mL/1L Spray Topical 75 L/100L Gel Topical 0.64 mL/1mL Liquid Topical 500 mg/1mL Liquid Topical 910 mg/1mL Kit Ophthalmic; Oral; Topical Swab Topical 0.07 mL/1mL Spray Topical 0.7 mL/1mL Liquid Topical 187.5 mL/250mL Gel Topical 2839 mL/3785mL Liquid Topical 2839 mL/3785mL Cloth Topical 0.45 1/1 Liquid Topical 350 g/100g Injection, solution; injection, suspension; kit Infiltration; Intra-articular; Intralesional; Intramuscular; Perineural; Topical Gel Topical 42 mL/60mL Gel Topical 0.722 mL/1mL Spray Topical 0.67 mL/50mL Aerosol Topical 75 mL/100mL Aerosol, spray Topical 75 mL/100mL Cloth Topical 0.85 1/1 Cloth Topical 75 mL/100mL Gel Extracorporeal 70 mL/100mL Gel Topical 0.705 mL/1mL Gel Topical 0.75 mL/1mL Gel Topical 14 mL/20mL Gel Topical 175 mL/250mL Gel Topical 21 mL/30mL Gel Topical 2800 mL/4000mL Gel Topical 350 mL/500mL Gel Topical 375 mL/500mL Gel Topical 42 mL/100mL Gel Topical 450 mL/450mL Gel Topical 64 mL/100mL Gel Topical 70 mL/70mL Gel Topical 70.1 mL/70.1mL Gel Topical 70.264 mL/100mL Gel Topical 70.92 mL/100mL Gel Topical 71 mL/100mL Gel Topical 71.7 mL/100mL Gel Topical 75.59 mL/100mL Gel Topical 75.69 mL/100mL Gel Topical 80 mL/100mL Gel Topical 87.5 mL/125mL Gel, metered Topical 75 mL/100mL Liquid Cutaneous 75 mL/100mL Liquid Cutaneous; Topical 75 mL/100mL Liquid Topical 1.325 L/1.893L Liquid Topical 14195.29 mL/18927.05mL Liquid Topical 148.38 L/197.84L Liquid Topical 156148.16 mL/208197.55mL Liquid Topical 2.835 L/3.78L Liquid Topical 27 mL/29mL Liquid Topical 2838 mL/3784mL Liquid Topical 2839.06 mL/3785.42mL Liquid Topical 2855.7 mL/3800mL Liquid Topical 3 L/4L Liquid Topical 3000 mL/4000mL Liquid Topical 3085.3 mL/3800mL Liquid Topical 3742.2 mL/3780mL Liquid Topical 375 mL/500mL Liquid Topical 7.5 L/10L Liquid Topical 70 1/1001 Liquid Topical 70.929 mL/100mL Liquid Topical 72 mL/100mL Liquid Topical 75 mL/200mL Liquid Topical 75.15 mL/100mL Liquid Topical 750 mL/1L Liquid Topical 750 mL/1000mL Liquid Topical 80 mL/100mL Liquid Topical 99 mL/99mL Lotion, augmented Topical 75 mL/100mL Ointment Topical 75 mL/100mL Solution Topical 2.835 L/3.78L Solution Topical 3.75 L/5L Solution Topical 375 mL/500mL Solution Topical 75 mL/75mL Solution Topical 75 L/3.785L Solution Topical 75 L/100L Solution Topical 75.6818 mL/100mL Solution Topical 7576 mL/10000mL Solution, concentrate Topical 99 mL/100mL Solution, gel forming / drops Cutaneous; Topical 75 mL/100mL Spray Topical Spray Topical 100 mL/100mL Spray Topical 150 mL/200mL Spray Topical 37.5 mL/50mL Spray Topical 41.3 mL/59mL Spray Topical 6.75 mL/9mL Spray Topical 67 mL/100mL Spray Topical 72 g/100g Spray Topical 75 kg/100kg Spray Topical 81.75 mL/109mL Spray, suspension Topical 75 mL/100mL Gel Extracorporeal; Topical 75 L/100L Gel Extracorporeal; Topical 75 mL/100mL Aerosol, foam Topical 75 mL/100mL Gel Topical 0.7 mL/1mL Solution Topical 0.75 kg/1kg Gel Topical 0.73 mL/1mL Solution Topical 0.75 mL/1mL Liquid Topical 60.67 mL/100mL Swab Topical 67 mL/1001 Cloth Topical 3.3 mL/1 Cloth Topical 70 1/1001 Liquid Topical 0.75 L/1L Solution Topical 1 mL/1mL Liquid Topical 80 g/100g Gel Topical 75 mL/100mL Gel Topical 62.09 mL/88.7mL Liquid Topical 700 mg/1mL Injection, suspension; kit Subcutaneous; Topical Liquid Cutaneous 750 mL/1L Gel Topical 70.0 1/100L Gel Topical 75.0 L/100L Liquid Topical 70.0 L/100L Liquid Topical 75.0 L/100L Liquid Topical 75.0249 L/100L Liquid Topical 80.0992 L/100L Liquid Topical 80.1003 L/100L Liquid Topical 80.0691 L/100L Liquid Topical 75.0271 L/100L Gel Topical 75.0128 L/100L Gel Topical 80.0836 L/100L Gel Topical 80.0847 L/100L Liquid Topical 80.087 L/100L Gel Topical 75.015 L/100L Cloth Topical 70 mL/100g Kit Epidural; Infiltration; Intra-articular; Topical Solution Topical 0.57 1/1 Liquid Topical; Vaginal Liquid Topical 83 mL/100mL Liquid Topical 83 mL/100g Swab Topical 0.7 g/1 Swab Cutaneous; Topical 75 mL/100mL Swab Topical 75 mL/100mL Solution / drops Topical 0.95 g/100mL Gel Topical 72 mL/100mL Gel Topical 73.71 mL/100mL Gel Cutaneous 73 mL/100mL Spray Topical 70 mL/100mL Liquid Topical 0.50 mL/1mL Liquid Topical 924 mg/1mL Solution Topical 462 mg/1mL Cloth Topical 2.97 g/1 Gel Topical 75.8 mL/100mL Liquid Topical .91 mg/1mL Liquid Topical .91 L/100L Liquid Topical 0.70 mg/1mL Liquid Topical 0.91 mg/1mL Liquid Topical 175 mL/350mL Liquid Topical 350 mL/500mL Liquid Topical 613 mg/1mL Liquid Topical 700 mL/1L Liquid Topical 91 mg/1mL Solution Topical 0.105 mL/0.15mL Solution Topical 30 mg/1mL Solution Topical 75 mL/60mL Solution Topical 750 g/1kg Solution Topical 91 mL/100mL Spray Topical 550.2 g/1L Spray Topical 700 mL/1L Swab Topical .7 mL/1 Swab Topical 0.75 g/1 Cloth Topical 7.5 mL/1 Liquid Topical 0.91 mL/1mL Liquid Topical 990 mg/100mL Liquid Topical 990 mg/1mL Soap Topical 75 mL/100mL Solution Topical 37.88 mL/50mL Spray Topical 750 mL/1L Cloth Topical 700 mg/1g Liquid Topical 75 L/100L Liquid Topical 99 % Solution Topical .70 mL/1mL Sponge Topical 0.07 mL/1mL Liquid Topical 0.7 mL/1mL Liquid Topical .7 mL/1mL Cloth Extracorporeal Cloth Topical 2.8 mL/1 Cloth Topical 3.75 mL/1 Cloth Topical 4.2 mL/1 Solution Topical 50 mL/100mL Liquid Cutaneous 350 mL/500mL Solution Topical 0.7 L/1L Solution Topical 700 mg/1mL Gel Topical 99 mL/100mL Liquid Topical 30 mg/1mL Liquid Topical 700 mg/100mL Liquid Extracorporeal 187.5 mL/250mL Solution Topical 0.7 mL/1mL Solution Topical 90 mL/100mL Liquid Topical 99 mL/100mL Swab Topical 70 mL/100mL Gel Topical 65 mL/100mL Cloth Cutaneous; Topical Swab Cutaneous; Topical 70 mL/100mL Cloth Topical 0.25 g/1 Spray Topical 75 mL/100mL Spray Topical 1 mL/1mL Cloth; cream; gel; kit; ointment; solution Ophthalmic; Topical Kit Ophthalmic Solution Topical 700 g/1L Spray Topical 15 g/100g Injection, solution; kit Subcutaneous; Topical Injection, solution; kit; swab Subcutaneous; Topical Kit Subcutaneous Kit Subcutaneous; Topical Injection; kit Parenteral; Topical Liquid Topical 65 mL/100mL Injection, solution; kit; solution Intravenous; Topical Gel Cutaneous Liquid Topical Kit Epidural; Infiltration; Intra-articular; Intramuscular; Topical Injection, powder, lyophilized, for suspension; kit; tablet Intramuscular; Oral; Topical Injection, powder, lyophilized, for suspension; kit Intramuscular; Topical Spray Topical 95.07 mL/100mL Salve Topical 0.25 mL/120mL Liquid Topical 10 g/100g Kit Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular; Topical Swab Topical 0.70 mL/1mL Spray Topical 44.69 mL/59mL Cloth Topical 70 mL/100mL Cloth Topical 0.7 mL/1 Cloth Topical 0.7 g/1 Gel Topical 56.8 mL/71mL Liquid Topical 630 mg/1g Liquid Topical 700 mL/1000mL Kit Infiltration; Intra-articular; Intralesional; Intramuscular; Soft tissue; Topical Liquid Topical 97.79 % Solution / drops Auricular (otic) 950 mg/1mL Liquid Topical 71 mL/100mL Injection, solution; kit Epidural; Intracaudal; Intramuscular; Intravenous; Perineural; Topical Aerosol, spray Topical Liquid Extracorporeal; Topical 75 mL/100mL Swab Topical 0.8 g/1 Swab Topical 1.59 g/1 Liquid Topical 75.17 mL/100mL Gel Topical 7.5 mL/1 Gel Topical 74 mL/100mL Solution Auricular (otic) 0.95 g/1mL Injection, solution; injection, suspension; kit Infiltration; Intra-articular; Intramuscular; Perineural; Topical Stick Topical 70 % Liquid Topical 88.5 mL/118mL Injection, solution; kit; solution Epidural; Infiltration; Intracaudal; Intravenous; Perineural; Topical Injection, suspension; kit; solution Intra-articular; Intralesional; Intramuscular; Soft tissue; Topical Injection, solution; injection, suspension; kit; solution Epidural; Infiltration; Intra-articular; Intracaudal; Intralesional; Intramuscular; Intravenous; Perineural; Soft tissue; Topical Injection, suspension; kit; solution Intra-articular; Intramuscular; Topical Injection, solution; injection, suspension; kit; solution Epidural; Infiltration; Intra-articular; Intracaudal; Intramuscular; Intravenous; Perineural; Topical Injection; injection, solution; kit; solution Epidural; Intracaudal; Intravenous; Perineural; Topical Injection, solution; kit; solution Epidural; Intracaudal; Intravenous; Perineural; Topical Solution Topical 77.6 L/100L Liquid Topical 1 mL/1 Kit Intramuscular; Subcutaneous; Topical Kit Infiltration; Soft tissue; Topical Kit Epidural; Infiltration; Intracaudal; Perineural Kit Epidural; Infiltration; Intracaudal Liquid Topical 2.846 L/3.785L Solution Topical 2.839 L/3.785L Swab Topical 700 mg/1mL Liquid Topical 75 mL/100mL Cloth Topical 0.75 1/1 Cloth Topical 75 1/1001 Solution Topical 305.9 mL/437mL Gel Topical 49 % Gel Topical Cloth Topical 75 mL/1001 Gel Topical 70 g/100g Sponge Topical Spray Topical 42 g/56g Cloth; kit; spray Topical Spray Topical 21.1 mL/30mL Solution Liquid Topical 0.45 mg/1g Solution Topical 99 mL/100mL Cloth Cutaneous; Topical 72.5 mg/100mg Swab Topical 0.7 mL/1g Solution Topical 75 mL/100mL Liquid Topical 75 mL/75mL Gel Topical 72 mg/100mL Spray Topical 72 mg/100mL Liquid Topical 72 L/100L Cloth Topical 75 mL/100g Cloth Topical 0.7 U/1U Gel Topical 750 L/1000L Liquid Topical 750 L/1000L Solution / drops Topical 75 mL/100mL Liquid Nasal 70 mL/100g Gel Topical 75 mL/75mL Cloth Topical 150 mL/501 Gel Topical 0.72 L/1L Cloth Topical 1 mL/1 Cloth Topical 75 g/100g Cloth Topical 70 mL/1001 Cloth Topical 0.75 mL/1g Cloth Topical 3 mL/1 Liquid Topical 0.7515 mL/1mL Solution Topical 1.75 mL/25mL Soap Topical Gel Topical 700 g/1kg Cloth Topical 0.75 mL/1mL Solution Topical 70 L/100L Gel Topical 700 mL/1L Cloth Topical 0.7 mL/1mL Cream Topical 70 mL/100mL Solution; sponge Topical Liquid Extracorporeal 180 mL/240mL Liquid Extracorporeal 225 mL/300mL Liquid Extracorporeal 37.5 mL/50mL Liquid Extracorporeal 375 mL/500mL Liquid Extracorporeal 3750 mL/5000mL Liquid Extracorporeal 45 mL/60mL Liquid Extracorporeal 75 mL/100mL Liquid Extracorporeal 750 mL/1000mL Liquid Extracorporeal 90 mL/120mL Solution Topical 75 L/100mL Patch Topical 0.7 mL/1mL Liquid Topical 0.8 g/1mL Solution Topical Liquid Topical 70 L/100L Liquid Topical 95 mL / 100 mL Gel Topical 63 g Stick Topical 70 1/1001 Solution Auricular (otic) 950 mg/1mL Injection; kit Intramuscular; Topical Lotion Topical 70 mL/100mL Kit Topical Liquid Topical 70.14 g/100mL Solution Topical 0.13 g/1mL Kit Intravenous; Topical Liquid Topical 0.7 mL/0.7mL Cloth Extracorporeal 75 mL/100mL Liquid Topical 99.9 mL/100mL Gel Topical 17.4585 g/29.6mL Liquid Topical 90 mL/100mL Cloth Topical Solution Topical 165.9 mL/237mL Solution Topical 1.155 mL/1 Gel Topical 65 % Cloth Topical 80.0852 L/100L Solution Topical 336 mL/480mL Gel Topical 74 L/100L Solution Topical 0.28 mL/1 Liquid Topical 63 mL/100mL Liquid Topical 0.7 mL/1 Sponge Topical .7 1/.7mL Sponge Topical .7 mL/.7mL Kit; patch; swab Topical Cloth Topical 55 1/1001 Sponge Topical 0.7 mL/0.7mL Solution 77.77 ml/100ml Solution 70 ml/100ml - Prices
- Not Available
- Patents
Patent Number Pediatric Extension Approved Expires (estimated) Region US6036976 No 2000-03-14 2016-12-13 US US7422388 No 2008-09-09 2027-04-25 US US6536975 No 2003-03-25 2020-11-10 US US6729786 No 2004-05-04 2023-03-14 US US7241065 No 2007-07-10 2023-03-14 US US5690958 No 1997-11-25 2016-09-30 US US6991394 No 2006-01-31 2024-01-31 US US7182536 No 2007-02-27 2023-12-30 US US5538353 No 1996-07-23 2015-08-25 US US5772346 No 1998-06-30 2017-04-22 US USD468424 No 2003-01-07 2017-01-07 US US9295657 No 2016-03-29 2035-03-13 US US9119876 No 2015-09-01 2035-03-13 US US8623935 No 2014-01-07 2029-07-26 US US9629368 No 2017-04-25 2028-05-23 US US9844654 No 2017-12-19 2036-04-24 US US10688291 No 2020-06-23 2034-12-20 US US8389583 No 2013-03-05 2029-08-09 US US8703828 No 2014-04-22 2028-05-23 US US8226971 No 2012-07-24 2025-05-06 US US9011897 No 2015-04-21 2025-02-08 US
Properties
- State
- Solid
- Experimental Properties
Property Value Source melting point (°C) -89.5 °C PhysProp boiling point (°C) 82.3 °C PhysProp water solubility 1E+006 mg/L (at 25 °C) RIDDICK,JA ET AL. (1986) logP 0.05 HANSCH,C ET AL. (1995) pKa 17.1 SERJEANT,EP & DEMPSEY,B (1979) - Predicted Properties
Property Value Source Water Solubility 378.0 mg/mL ALOGPS logP 0.04 ALOGPS logP 0.25 Chemaxon logS 0.8 ALOGPS pKa (Strongest Acidic) 17.26 Chemaxon pKa (Strongest Basic) -1.8 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 17.43 m3·mol-1 Chemaxon Polarizability 7.14 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
Property Value Probability Human Intestinal Absorption + 0.9905 Blood Brain Barrier + 0.9694 Caco-2 permeable + 0.7135 P-glycoprotein substrate Non-substrate 0.8146 P-glycoprotein inhibitor I Non-inhibitor 0.9609 P-glycoprotein inhibitor II Non-inhibitor 0.9785 Renal organic cation transporter Non-inhibitor 0.932 CYP450 2C9 substrate Non-substrate 0.8061 CYP450 2D6 substrate Non-substrate 0.8916 CYP450 3A4 substrate Non-substrate 0.7103 CYP450 1A2 substrate Non-inhibitor 0.8634 CYP450 2C9 inhibitor Non-inhibitor 0.9466 CYP450 2D6 inhibitor Non-inhibitor 0.9581 CYP450 2C19 inhibitor Non-inhibitor 0.9267 CYP450 3A4 inhibitor Non-inhibitor 0.9764 CYP450 inhibitory promiscuity Low CYP Inhibitory Promiscuity 0.949 Ames test Non AMES toxic 0.9246 Carcinogenicity Carcinogens 0.7397 Biodegradation Ready biodegradable 0.7608 Rat acute toxicity 1.3372 LD50, mol/kg Not applicable hERG inhibition (predictor I) Weak inhibitor 0.9583 hERG inhibition (predictor II) Non-inhibitor 0.9457
Spectra
- Mass Spec (NIST)
- Download (3.84 KB)
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 98.2168216 predictedDarkChem Lite v0.1.0 [M-H]- 98.2450216 predictedDarkChem Lite v0.1.0 [M-H]- 98.1942216 predictedDarkChem Lite v0.1.0 [M-H]- 98.2359216 predictedDarkChem Lite v0.1.0 [M-H]- 120.13784 predictedDeepCCS 1.0 (2019) [M+H]+ 99.0474216 predictedDarkChem Lite v0.1.0 [M+H]+ 99.2250216 predictedDarkChem Lite v0.1.0 [M+H]+ 99.0675216 predictedDarkChem Lite v0.1.0 [M+H]+ 99.2683216 predictedDarkChem Lite v0.1.0 [M+H]+ 122.03325 predictedDeepCCS 1.0 (2019) [M+Na]+ 98.3364216 predictedDarkChem Lite v0.1.0 [M+Na]+ 98.3669216 predictedDarkChem Lite v0.1.0 [M+Na]+ 98.4543216 predictedDarkChem Lite v0.1.0 [M+Na]+ 130.1671 predictedDeepCCS 1.0 (2019)
Drug created at June 13, 2005 13:24 / Updated at February 20, 2024 23:55