Identification
- Generic Name
- Nicotinamide adenine dinucleotide phosphate
- DrugBank Accession Number
- DB03461
- Background
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Nicotinamide adenine dinucleotide phosphate (DB03461)
- Weight
- Average: 743.405
Monoisotopic: 743.075452041 - Chemical Formula
- C21H28N7O17P3
- Synonyms
- Codehydrase II
- Codehydrogenase II
- Coenzyme II
- Triphosphopyridine nucleotide
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
Target Actions Organism UIsocitrate dehydrogenase [NADP] Not Available Escherichia coli (strain K12) UAldose reductase Not Available Humans UGlucose-6-phosphate 1-dehydrogenase Not Available Leuconostoc mesenteroides UAldo-keto reductase family 1 member C2 Not Available Humans UEstradiol 17-beta-dehydrogenase 1 Not Available Humans UNAD(P) transhydrogenase, mitochondrial Not Available Humans UCorticosteroid 11-beta-dehydrogenase isozyme 1 Not Available Humans USepiapterin reductase Not Available Humans UPteridine reductase 1 Not Available Leishmania major UL-xylulose reductase Not Available Humans UIsocitrate dehydrogenase [NADP] cytoplasmic Not Available Humans UAldo-keto reductase family 1 member C1 Not Available Humans UNitric oxide synthase, brain Not Available Humans UGlucose-6-phosphate 1-dehydrogenase Not Available Humans UDihydrofolate reductase Not Available Humans UADP-L-glycero-D-manno-heptose-6-epimerase Not Available Escherichia coli (strain K12) UC-1-tetrahydrofolate synthase, cytoplasmic Not Available Humans UAldo-keto reductase family 1 member C3 Not Available Humans UFlavin reductase (NADPH) Not Available Humans UIsocitrate dehydrogenase [NADP] Not Available Azotobacter vinelandii UDihydrofolate reductase Not Available Pneumocystis carinii UQuinone oxidoreductase Not Available Humans U3-hydroxy-3-methylglutaryl-coenzyme A reductase Not Available Humans UAlcohol dehydrogenase 1B Not Available Humans UNADPH--cytochrome P450 reductase Not Available Humans UShikimate dehydrogenase Not Available Escherichia coli (strain K12) UNADP-dependent isopropanol dehydrogenase Not Available Thermoanaerobacter brockii UGDP-L-fucose synthase Not Available Escherichia coli (strain K12) UAspartate-semialdehyde dehydrogenase Not Available Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) U2,4-dienoyl-CoA reductase [NADPH] Not Available Escherichia coli (strain K12) UNADP-dependent malic enzyme Not Available Humans UDihydrofolate reductase Not Available Escherichia coli (strain K12) UNAD(P) transhydrogenase subunit beta Not Available Rhodospirillum rubrum U3-oxoacyl-[acyl-carrier-protein] reductase FabG Not Available Escherichia coli (strain K12) UDehydrogenase/reductase SDR family member 11 Not Available Humans UMalate dehydrogenase, cytoplasmic Not Available Humans UOxidoreductase YdhF Not Available Escherichia coli (strain K12) UPutative pteridine reductase 2 Not Available Trypanosoma cruzi UEstradiol 17-beta-dehydrogenase 8 Not Available Humans UAlcohol dehydrogenase [NADP(+)] Not Available Humans UPutative ketoacyl reductase Not Available Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) U2,4-dienoyl-CoA reductase, mitochondrial Not Available Humans UOxidoreductase, short chain dehydrogenase/reductase family Not Available Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) UProstaglandin F synthase Not Available Trypanosoma brucei brucei UGeneral stress protein 69 Not Available Bacillus subtilis (strain 168) UFerredoxin--NADP reductase Not Available Anabaena sp. (strain PCC 7119) UBifunctional protein MdtA Not Available Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1) UAlcohol dehydrogenase Not Available Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) UNADPH:adrenodoxin oxidoreductase, mitochondrial Not Available Humans UFerredoxin--NADP reductase Not Available Nostoc sp. (strain PCC 7120 / UTEX 2576) U2,5-diketo-D-gluconic acid reductase A Not Available Corynebacterium sp. (strain ATCC 31090) UProtein IolS Not Available Bacillus subtilis (strain 168) UNADP-dependent glyceraldehyde-3-phosphate dehydrogenase Not Available Streptococcus mutans serotype c (strain ATCC 700610 / UA159) UProstaglandin reductase 1 Not Available Humans USulfite reductase [NADPH] flavoprotein alpha-component Not Available Escherichia coli (strain K12) UAldo-keto reductase family 1 member B10 Not Available Humans UAlcohol dehydrogenase (NADP(+)) Not Available Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) UNADP-dependent fatty aldehyde dehydrogenase Not Available Vibrio harveyi UPutative dehydrogenase/reductase SDR family member 4-like 2 Not Available Humans UAldehyde reductase Not Available Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) - Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
- Kingdom
- Organic compounds
- Super Class
- Nucleosides, nucleotides, and analogues
- Class
- (5'->5')-dinucleotides
- Sub Class
- Not Available
- Direct Parent
- (5'->5')-dinucleotides
- Alternative Parents
- Purine nucleotide sugars / Purine ribonucleoside diphosphates / Purine ribonucleoside 2',5'-bisphosphates / Nicotinamide nucleotides / Pentose phosphates / Glycosylamines / Monosaccharide phosphates / 6-aminopurines / Organic pyrophosphates / Nicotinamides show 16 more
- Substituents
- (5'->5')-dinucleotide / 6-aminopurine / Alcohol / Alkyl phosphate / Amine / Aminopyrimidine / Aromatic heteropolycyclic compound / Azacycle / Azole / Carboximidic acid show 40 more
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- NADP (CHEBI:44409)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- BY8P107XEP
- CAS number
- 53-59-8
- InChI Key
- XJLXINKUBYWONI-NNYOXOHSSA-N
- InChI
- InChI=1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
- IUPAC Name
- 1-[(2R,3R,4S,5R)-5-{[({[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl phosphonato)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-1lambda5-pyridin-1-ylium
- SMILES
- NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O
References
- General References
- Not Available
- External Links
- PubChem Compound
- 57525501
- PubChem Substance
- 46507953
- ChemSpider
- 5674
- BindingDB
- 11939
- ChEBI
- 44409
- ChEMBL
- CHEMBL295069
- PDBe Ligand
- NAP
- Wikipedia
- Nicotinamide_adenine_dinucleotide_phosphate
- PDB Entries
- 1a27 / 1ads / 1ae1 / 1ae4 / 1afs / 1ah0 / 1ah3 / 1ah4 / 1ai2 / 1amo … show 1734 more
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 4.84 mg/mL ALOGPS logP -0.81 ALOGPS logP -11 Chemaxon logS -2.2 ALOGPS pKa (Strongest Acidic) 0.66 Chemaxon pKa (Strongest Basic) 4.87 Chemaxon Physiological Charge -3 Chemaxon Hydrogen Acceptor Count 17 Chemaxon Hydrogen Donor Count 8 Chemaxon Polar Surface Area 367.62 Å2 Chemaxon Rotatable Bond Count 13 Chemaxon Refractivity 151.75 m3·mol-1 Chemaxon Polarizability 62.91 Å3 Chemaxon Number of Rings 5 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
Property Value Probability Human Intestinal Absorption - 0.9635 Blood Brain Barrier + 0.8652 Caco-2 permeable - 0.7266 P-glycoprotein substrate Non-substrate 0.5521 P-glycoprotein inhibitor I Non-inhibitor 0.9002 P-glycoprotein inhibitor II Non-inhibitor 0.9526 Renal organic cation transporter Non-inhibitor 0.9324 CYP450 2C9 substrate Non-substrate 0.8216 CYP450 2D6 substrate Non-substrate 0.8331 CYP450 3A4 substrate Non-substrate 0.5256 CYP450 1A2 substrate Non-inhibitor 0.882 CYP450 2C9 inhibitor Non-inhibitor 0.9148 CYP450 2D6 inhibitor Non-inhibitor 0.9136 CYP450 2C19 inhibitor Non-inhibitor 0.9027 CYP450 3A4 inhibitor Non-inhibitor 0.8838 CYP450 inhibitory promiscuity Low CYP Inhibitory Promiscuity 0.9353 Ames test Non AMES toxic 0.8477 Carcinogenicity Non-carcinogens 0.9055 Biodegradation Not ready biodegradable 0.9649 Rat acute toxicity 2.8018 LD50, mol/kg Not applicable hERG inhibition (predictor I) Weak inhibitor 0.9756 hERG inhibition (predictor II) Non-inhibitor 0.6527
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (â„«2) Source type Source [M-H]- 286.2451343 predictedDarkChem Lite v0.1.0 [M-H]- 210.65393 predictedDeepCCS 1.0 (2019) [M+H]+ 288.1371343 predictedDarkChem Lite v0.1.0 [M+H]+ 212.50032 predictedDeepCCS 1.0 (2019) [M+Na]+ 287.6191343 predictedDarkChem Lite v0.1.0 [M+Na]+ 218.648 predictedDeepCCS 1.0 (2019)
Targets
Build, predict & validate machine-learning models
Use our structured and evidence-based datasets to unlock newinsights and accelerate drug research.
Use our structured and evidence-based datasets to unlock new insights and accelerate drug research.
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Nad binding
- Specific Function
- Not Available
- Gene Name
- icd
- Uniprot ID
- P08200
- Uniprot Name
- Isocitrate dehydrogenase [NADP]
- Molecular Weight
- 45756.335 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Glyceraldehyde oxidoreductase activity
- Specific Function
- Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
- Gene Name
- AKR1B1
- Uniprot ID
- P15121
- Uniprot Name
- Aldose reductase
- Molecular Weight
- 35853.125 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Leuconostoc mesenteroides
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone. Can utilize either NADP(+) or NAD(+).
- Gene Name
- zwf
- Uniprot ID
- P11411
- Uniprot Name
- Glucose-6-phosphate 1-dehydrogenase
- Molecular Weight
- 54440.585 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
- Specific Function
- Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent...
- Gene Name
- AKR1C2
- Uniprot ID
- P52895
- Uniprot Name
- Aldo-keto reductase family 1 member C2
- Molecular Weight
- 36734.97 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Testosterone dehydrogenase (nad+) activity
- Specific Function
- Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
- Gene Name
- HSD17B1
- Uniprot ID
- P14061
- Uniprot Name
- Estradiol 17-beta-dehydrogenase 1
- Molecular Weight
- 34949.715 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxi...
- Gene Name
- NNT
- Uniprot ID
- Q13423
- Uniprot Name
- NAD(P) transhydrogenase, mitochondrial
- Molecular Weight
- 113894.595 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- 11-beta-hydroxysteroid dehydrogenase [nad(p)] activity
- Specific Function
- Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the rea...
- Gene Name
- HSD11B1
- Uniprot ID
- P28845
- Uniprot Name
- Corticosteroid 11-beta-dehydrogenase isozyme 1
- Molecular Weight
- 32400.665 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Sepiapterin reductase activity
- Specific Function
- Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
- Gene Name
- SPR
- Uniprot ID
- P35270
- Uniprot Name
- Sepiapterin reductase
- Molecular Weight
- 28048.13 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Leishmania major
- Pharmacological action
- Unknown
- General Function
- Thymidylate synthase activity
- Specific Function
- Exhibits a NADPH-dependent biopterin reductase activity. Has good activity with folate and significant activity with dihydrofolate and dihydrobiopterin, but not with quinonoid dihydrobiopterin. Con...
- Gene Name
- PTR1
- Uniprot ID
- Q01782
- Uniprot Name
- Pteridine reductase 1
- Molecular Weight
- 30456.315 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity, acting on nad(p)h, quinone or similar compound as acceptor
- Specific Function
- Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role i...
- Gene Name
- DCXR
- Uniprot ID
- Q7Z4W1
- Uniprot Name
- L-xylulose reductase
- Molecular Weight
- 25912.875 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Receptor binding
- Specific Function
- Not Available
- Gene Name
- IDH1
- Uniprot ID
- O75874
- Uniprot Name
- Isocitrate dehydrogenase [NADP] cytoplasmic
- Molecular Weight
- 46659.005 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
- Specific Function
- Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the in...
- Gene Name
- AKR1C1
- Uniprot ID
- Q04828
- Uniprot Name
- Aldo-keto reductase family 1 member C1
- Molecular Weight
- 36788.02 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Tetrahydrobiopterin binding
- Specific Function
- Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. P...
- Gene Name
- NOS1
- Uniprot ID
- P29475
- Uniprot Name
- Nitric oxide synthase, brain
- Molecular Weight
- 160969.095 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Protein homodimerization activity
- Specific Function
- Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is ...
- Gene Name
- G6PD
- Uniprot ID
- P11413
- Uniprot Name
- Glucose-6-phosphate 1-dehydrogenase
- Molecular Weight
- 59256.31 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Nadph binding
- Specific Function
- Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA pre...
- Gene Name
- DHFR
- Uniprot ID
- P00374
- Uniprot Name
- Dihydrofolate reductase
- Molecular Weight
- 21452.61 Da
References
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Nadp+ binding
- Specific Function
- Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
- Gene Name
- hldD
- Uniprot ID
- P67910
- Uniprot Name
- ADP-L-glycero-D-manno-heptose-6-epimerase
- Molecular Weight
- 34892.905 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Methylenetetrahydrofolate dehydrogenase [nad(p)+] activity
- Specific Function
- Not Available
- Gene Name
- MTHFD1
- Uniprot ID
- P11586
- Uniprot Name
- C-1-tetrahydrofolate synthase, cytoplasmic
- Molecular Weight
- 101558.37 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
- Specific Function
- Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2....
- Gene Name
- AKR1C3
- Uniprot ID
- P42330
- Uniprot Name
- Aldo-keto reductase family 1 member C3
- Molecular Weight
- 36852.89 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Riboflavin reductase (nadph) activity
- Specific Function
- Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone)....
- Gene Name
- BLVRB
- Uniprot ID
- P30043
- Uniprot Name
- Flavin reductase (NADPH)
- Molecular Weight
- 22119.215 Da
References
- Kind
- Protein
- Organism
- Azotobacter vinelandii
- Pharmacological action
- Unknown
- General Function
- Metal ion binding
- Specific Function
- Not Available
- Gene Name
- icd
- Uniprot ID
- P16100
- Uniprot Name
- Isocitrate dehydrogenase [NADP]
- Molecular Weight
- 80388.94 Da
References
- Kind
- Protein
- Organism
- Pneumocystis carinii
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
- Gene Name
- Not Available
- Uniprot ID
- P16184
- Uniprot Name
- Dihydrofolate reductase
- Molecular Weight
- 23883.325 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Zinc ion binding
- Specific Function
- Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substr...
- Gene Name
- CRYZ
- Uniprot ID
- Q08257
- Uniprot Name
- Quinone oxidoreductase
- Molecular Weight
- 35206.36 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Nadph binding
- Specific Function
- Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including...
- Gene Name
- HMGCR
- Uniprot ID
- P04035
- Uniprot Name
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase
- Molecular Weight
- 97475.155 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Zinc ion binding
- Specific Function
- Not Available
- Gene Name
- ADH1B
- Uniprot ID
- P00325
- Uniprot Name
- Alcohol dehydrogenase 1B
- Molecular Weight
- 39854.21 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, nad(p)h as one donor, and incorporation of one atom of oxygen
- Specific Function
- This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
- Gene Name
- POR
- Uniprot ID
- P16435
- Uniprot Name
- NADPH--cytochrome P450 reductase
- Molecular Weight
- 76689.12 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Shikimate 3-dehydrogenase (nadp+) activity
- Specific Function
- Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikim...
- Gene Name
- aroE
- Uniprot ID
- P15770
- Uniprot Name
- Shikimate dehydrogenase (NADP(+))
- Molecular Weight
- 29413.305 Da
References
- Kind
- Protein
- Organism
- Thermoanaerobacter brockii
- Pharmacological action
- Unknown
- General Function
- Zinc ion binding
- Specific Function
- Alcohol dehydrogenase with a preference for medium chain secondary alcohols, such as 2-butanol and isopropanol. Has very low activity with primary alcohols, such as ethanol. Under physiological con...
- Gene Name
- adh
- Uniprot ID
- P14941
- Uniprot Name
- NADP-dependent isopropanol dehydrogenase
- Molecular Weight
- 37646.685 Da
References
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Nadp+ binding
- Specific Function
- Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
- Gene Name
- fcl
- Uniprot ID
- P32055
- Uniprot Name
- GDP-L-fucose synthase
- Molecular Weight
- 36140.87 Da
References
- Kind
- Protein
- Organism
- Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
- Gene Name
- asd
- Uniprot ID
- P44801
- Uniprot Name
- Aspartate-semialdehyde dehydrogenase
- Molecular Weight
- 40538.52 Da
References
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Nadph dehydrogenase activity
- Specific Function
- Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-2- enoyl-CoA.
- Gene Name
- fadH
- Uniprot ID
- P42593
- Uniprot Name
- 2,4-dienoyl-CoA reductase [NADPH]
- Molecular Weight
- 72677.545 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Oxaloacetate decarboxylase activity
- Specific Function
- Not Available
- Gene Name
- ME1
- Uniprot ID
- P48163
- Uniprot Name
- NADP-dependent malic enzyme
- Molecular Weight
- 64149.075 Da
References
- Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [Article]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [Article]
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
- Gene Name
- folA
- Uniprot ID
- P0ABQ4
- Uniprot Name
- Dihydrofolate reductase
- Molecular Weight
- 17999.21 Da
References
- Kind
- Protein
- Organism
- Rhodospirillum rubrum
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
- Gene Name
- pntB
- Uniprot ID
- P0C188
- Uniprot Name
- NAD(P) transhydrogenase subunit beta
- Molecular Weight
- 47807.835 Da
References
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
- Gene Name
- fabG
- Uniprot ID
- P0AEK2
- Uniprot Name
- 3-oxoacyl-[acyl-carrier-protein] reductase FabG
- Molecular Weight
- 25560.065 Da
References
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- DHRS11
- Uniprot ID
- Q6UWP2
- Uniprot Name
- Dehydrogenase/reductase SDR family member 11
- Molecular Weight
- 28308.065 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Nad binding
- Specific Function
- Not Available
- Gene Name
- MDH1
- Uniprot ID
- P40925
- Uniprot Name
- Malate dehydrogenase, cytoplasmic
- Molecular Weight
- 36425.795 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- May function as oxidoreductase.
- Gene Name
- ydhF
- Uniprot ID
- P76187
- Uniprot Name
- Oxidoreductase YdhF
- Molecular Weight
- 33675.345 Da
- Kind
- Protein
- Organism
- Trypanosoma cruzi
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- ptr2
- Uniprot ID
- Q8I814
- Uniprot Name
- Putative pteridine reductase 2
- Molecular Weight
- 29204.015 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Testosterone dehydrogenase (nad+) activity
- Specific Function
- NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acy...
- Gene Name
- HSD17B8
- Uniprot ID
- Q92506
- Uniprot Name
- Estradiol 17-beta-dehydrogenase 8
- Molecular Weight
- 26973.56 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- L-glucuronate reductase activity
- Specific Function
- Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyd...
- Gene Name
- AKR1A1
- Uniprot ID
- P14550
- Uniprot Name
- Alcohol dehydrogenase [NADP(+)]
- Molecular Weight
- 36572.71 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- actIII
- Uniprot ID
- P16544
- Uniprot Name
- Putative ketoacyl reductase
- Molecular Weight
- 27264.88 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity, acting on nad(p)h
- Specific Function
- Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependen...
- Gene Name
- DECR1
- Uniprot ID
- Q16698
- Uniprot Name
- 2,4-dienoyl-CoA reductase, mitochondrial
- Molecular Weight
- 36067.4 Da
- Kind
- Protein
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- Not Available
- Uniprot ID
- Q9WYS2
- Uniprot Name
- Oxidoreductase, short chain dehydrogenase/reductase family
- Molecular Weight
- 27916.72 Da
- Kind
- Protein
- Organism
- Trypanosoma brucei brucei
- Pharmacological action
- Unknown
- General Function
- Prostaglandin-f synthase activity
- Specific Function
- Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitroben...
- Gene Name
- Not Available
- Uniprot ID
- Q9GV41
- Uniprot Name
- Prostaglandin F synthase
- Molecular Weight
- 30992.385 Da
- Kind
- Protein
- Organism
- Bacillus subtilis (strain 168)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- yhdN
- Uniprot ID
- P80874
- Uniprot Name
- General stress protein 69
- Molecular Weight
- 37311.93 Da
- Kind
- Protein
- Organism
- Anabaena sp. (strain PCC 7119)
- Pharmacological action
- Unknown
- General Function
- Nadp binding
- Specific Function
- Not Available
- Gene Name
- petH
- Uniprot ID
- P21890
- Uniprot Name
- Ferredoxin--NADP reductase
- Molecular Weight
- 48865.145 Da
- Kind
- Protein
- Organism
- Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1)
- Pharmacological action
- Unknown
- General Function
- Methylenetetrahydrofolate dehydrogenase (nadp+) activity
- Specific Function
- Catalyzes the dehydrogenation of methylene-H(4)MPT. Can also catalyze the reversible dehydrogenation of methylene-H(4)F with 20-fold lower catalytic efficiency.
- Gene Name
- mtdA
- Uniprot ID
- P55818
- Uniprot Name
- Bifunctional protein MdtA
- Molecular Weight
- 29735.595 Da
- Kind
- Protein
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- Not Available
- Uniprot ID
- Q9X022
- Uniprot Name
- Alcohol dehydrogenase, iron-containing
- Molecular Weight
- 39942.68 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Nadph-adrenodoxin reductase activity
- Specific Function
- Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adr...
- Gene Name
- FDXR
- Uniprot ID
- P22570
- Uniprot Name
- NADPH:adrenodoxin oxidoreductase, mitochondrial
- Molecular Weight
- 53836.36 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Nostoc sp. (strain PCC 7120 / UTEX 2576)
- Pharmacological action
- Unknown
- General Function
- Ferredoxin-nadp+ reductase activity
- Specific Function
- Not Available
- Gene Name
- petH
- Uniprot ID
- P58558
- Uniprot Name
- Ferredoxin--NADP reductase
- Molecular Weight
- 48838.075 Da
- Kind
- Protein
- Organism
- Corynebacterium sp. (strain ATCC 31090)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and dihydroxyacetone can also serve as substrates. 25DKGR-A exhibits a greater selec...
- Gene Name
- dkgA
- Uniprot ID
- P06632
- Uniprot Name
- 2,5-diketo-D-gluconic acid reductase A
- Molecular Weight
- 30118.485 Da
- Kind
- Protein
- Organism
- Bacillus subtilis (strain 168)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- iolS
- Uniprot ID
- P46336
- Uniprot Name
- Protein IolS
- Molecular Weight
- 35167.595 Da
- Kind
- Protein
- Organism
- Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
- Pharmacological action
- Unknown
- General Function
- Glyceraldehyde-3-phosphate dehydrogenase (nadp+) (phosphorylating) activity
- Specific Function
- Not Available
- Gene Name
- gapN
- Uniprot ID
- Q59931
- Uniprot Name
- NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
- Molecular Weight
- 51193.14 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Zinc ion binding
- Specific Function
- Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversio...
- Gene Name
- PTGR1
- Uniprot ID
- Q14914
- Uniprot Name
- Prostaglandin reductase 1
- Molecular Weight
- 35869.64 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Escherichia coli (strain K12)
- Pharmacological action
- Unknown
- General Function
- Sulfite reductase (nadph) activity
- Specific Function
- Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate....
- Gene Name
- cysJ
- Uniprot ID
- P38038
- Uniprot Name
- Sulfite reductase [NADPH] flavoprotein alpha-component
- Molecular Weight
- 66269.23 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Retinal dehydrogenase activity
- Specific Function
- Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldeh...
- Gene Name
- AKR1B10
- Uniprot ID
- O60218
- Uniprot Name
- Aldo-keto reductase family 1 member B10
- Molecular Weight
- 36019.295 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- Not Available
- Uniprot ID
- Q9WZS7
- Uniprot Name
- NADH-dependent butanol dehydrogenase A
- Molecular Weight
- 43354.78 Da
- Kind
- Protein
- Organism
- Vibrio harveyi
- Pharmacological action
- Unknown
- General Function
- Aldehyde dehydrogenase (nadp+) activity
- Specific Function
- Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emittin...
- Gene Name
- aldH
- Uniprot ID
- Q56694
- Uniprot Name
- NADP-dependent fatty aldehyde dehydrogenase
- Molecular Weight
- 54459.035 Da
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Putative oxidoreductase.
- Gene Name
- DHRS4L1
- Uniprot ID
- P0CG22
- Uniprot Name
- Putative dehydrogenase/reductase SDR family member 4-like 1
- Molecular Weight
- 30607.35 Da
References
- Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [Article]
- Kind
- Protein
- Organism
- Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
- Pharmacological action
- Unknown
- General Function
- Oxidoreductase activity
- Specific Function
- Not Available
- Gene Name
- Not Available
- Uniprot ID
- Q9X0A2
- Uniprot Name
- Oxidoreductase, aldo/keto reductase family
- Molecular Weight
- 33244.185 Da
Drug created at June 13, 2005 13:24 / Updated at June 12, 2020 16:52