Magnesium chloride

Identification

Summary

Magnesium chloride is an ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies.

Brand Names

Bss, Bss Ophthalmic Solution, Cardioplegic, Chloromag, Citrasate, Clinimix E 2.75/5, Dianeal, Dianeal Low Calcium 1.5, Dianeal Pd-2/1.5, Extraneal, Eye Stream, H.E.L.P.bicel, Hemosate Ultra, Hyperlyte, Ionosol-MB, Isolyte P, Isolyte S, Isolyte S pH 7.4, Isoplate, Naturalyte, Normosol-R, Nxstage Pureflow, Olimel, Periolimel, Phoxillum, Physiolyte, Physioneal 40, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Plegisol, Prismasol, Selectbag One

Generic Name

Magnesium chloride

DrugBank Accession Number

DB09407

Background

Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

Type

Small Molecule

Groups

Approved

Structure

Download

MOLSDFPDBSMILESInChI

Similar Structures

Structure for Magnesium chloride (DB09407)

×

Close

Weight

Average: 95.211
Monoisotopic: 93.922747312

Chemical Formula

Cl₂Mg

Synonyms

• Anhydrous magnesium chloride
• Magnesium chloride anhydrous

Poor quality drug data slowing you down?

Unlock 38% more drug discovery time and eliminate decision-making doubts with this one-stop guide to quality drug data.

Download eBook

Poor quality drug data slowing you down?

Download eBook

Pharmacology

Indication

Magnesium chloride is used in several medical and topical (skin related) applications. Magnesium chloride usp, anhydrous uses as electrolyte replenisher, pharmaceutic necessity for hemodialysis and peritoneal dialysis fluids.

Reduce drug development failure rates

Build, train, & validate machine-learning models
with evidence-based and structured datasets.

See how

Build, train, & validate predictive machine-learning models with structured datasets.

See how

Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Used in combination to treat	Electrolyte imbalance	Combination Product in combination with: Sodium chloride (DB09153), Sodium acetate (DB09395), Dextrose, unspecified form (DB09341), Gluconic Acid (DB13180), Potassium chloride (DB00761)	••••••••••••		•••••••• ••••••• ••••••	•••••••••• ••••••••
Treatment of	Magnesium deficiency		••• •••••
Used in combination to treat	Mild metabolic acidosis	Combination Product in combination with: Sodium chloride (DB09153), Potassium chloride (DB00761), Gluconic Acid (DB13180), Dextrose, unspecified form (DB09341), Sodium acetate (DB09395)	••••••••••••			•••••••••• ••••••••

Create Account

Associated Therapies

• Automated peritoneal dialysis
• Continuous Renal Replacement Therapy
• Continuous ambulatory peritoneal dialysis therapy
• Fluid replacement therapy
• Hemodialysis Treatment
• Irrigation therapy
• Organ Preservation
• Parenteral rehydration therapy
• Peritoneal dialysis therapy
• Total parenteral nutrition therapy
• Urine alkalinization therapy
• Fluid and electrolyte maintenance therapy

Contraindications & Blackbox Warnings

Prevent Adverse Drug Events Today

Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.

Learn more

Avoid life-threatening adverse drug events with our Clinical API

Learn more

Pharmacodynamics

Magnesium is important as a cofactor in many enzymatic reactions in the body involving protein synthesis and carbohydrate metabolism (at least 300 enzymatic reactions require magnesium). Actions on lipoprotein lipase have been found to be important in reducing serum cholesterol and on sodium/potassium ATPase in promoting polarization (eg, neuromuscular functioning).

Mechanism of action

Mechanism of action of magnesium chloride studied in 10 adult volunteers. Results suggested magnesium ion in duodenum is relatively weak stimulus to pancreas and gall bladder. It is weak stimulant to cholecystokinin release and inhibits net jejunal water absorption. The oral administration of a single 800 mg dose of magnesium chloride in healthy volunteers resulted in a diminished rate of intraluminal lipid and protein digestion. The most pronounced effect of magnesium chloride, however, was a decreased gastric emptying rate of both test meals. After correction for gastric emptying, no differences were noted in intraluminal lipid or protein digestion. Therefore, the lower lipid levels noted after magnesium supplementation are unlikely to be the result of altered lipid assimilation. Magnesium chloride slows gastric emptying but does not influence lipid digestion.

Absorption

Oral: Inversely proportional to amount ingested; 40% to 60% under controlled dietary conditions; 15% to 36% at higher doses

Volume of distribution

Bone (50% to 60%); extracellular fluid (1% to 2%)

Protein binding

30%, to albumin

Metabolism

Magnesium levels are efficiently regulated by the kidneys. Magnesium also undergoes efficient enterohepatic circulation

Route of elimination

Magnesium is excreted in urine. Unabsorbed magnesium is excreted in feces

Half-life

Elimination half-life has been reported to be 27.7 hours following an overdose of 400 mEq magnesium in an adult.

Clearance

Maximum magnesium clearance is directly proportional to creatinine clearance.

Adverse Effects

Improve decision support & research outcomes

With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!

See the data

Improve decision support & research outcomes with our structured adverse effects data.

See a data sample

Toxicity

Mouse LD50 775mg/kg (intraperitoneal) Mouse LD50 : 7600mg/kg (oral) Rat LD 50 : 8100mg/kg (oral) Rat LD50 176mg/kg (intravenous) Severe toxicity occurs most often after intravenous infusions. It can also occur after chronic excessive oral doses, often in patients with renal insufficiency. Early manifestations are lethargy, hyporeflexia, followed by weakness, paralysis, hypotension, ECG changes (prolonged PR and QRS intervals), CNS depression, seizures, and respiratory depression. In overdose, magnesium impairs neuromuscular transmission, manifested as weakness and hyporeflexia.

Pathways

Not Available

Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">

Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drug	Interaction
Integrate drug-drug interactions in your software
Abacavir	Abacavir may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
Aceclofenac	Aceclofenac may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
Acemetacin	Acemetacin may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
Acetaminophen	Acetaminophen may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
Acetazolamide	Acetazolamide may increase the excretion rate of Magnesium chloride which could result in a lower serum level and potentially a reduction in efficacy.

Food Interactions

• Take with or without food. Taking magnesium supplements with food may reduce the risk of diarrhea.

Products

Drug product information from 10+ global regions

Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.

Access now

Access drug product information from over 10 global regions.

Access now

Product Ingredients

Ingredient	UNII	CAS	InChI Key
Magnesium chloride hexahydrate	02F3473H9O	7791-18-6	DHRRIBDTHFBPNG-UHFFFAOYSA-L
Magnesium chloride hydrate	Not Available	22756-14-5	MJMDTFNVECGTEM-UHFFFAOYSA-L

Active Moieties

Name	Kind	UNII	CAS	InChI Key
Magnesium cation	ionic	T6V3LHY838	22537-22-0	JLVVSXFLKOJNIY-UHFFFAOYSA-N
Chloride ion	ionic	Q32ZN48698	16887-00-6	VEXZGXHMUGYJMC-UHFFFAOYSA-M

Brand Name Prescription Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Cepasium Sup 100mg	Suppository	100 mg / sup	Rectal	Laboratoires Cortunon Inc.	1980-12-31	1998-09-29
Chloromag	Injection, solution	200 mg/1mL	Intravenous	Merit Pharmaceutical	2011-06-11	Not applicable
Magnesium Chloride	Injection, solution	200 mg/1mL	Intravenous	American Therapeutic Medicines Inc.	2009-05-01	2010-12-30
Magnesium Chloride	Injection	200 mg/1mL	Intravenous	Mylan Institutional LLC	2013-03-14	Not applicable
Magnesium Chloride	Injection, solution	200 mg/1mL	Intravenous	Claris Lifesciences Limited	2009-10-07	2010-11-04

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Formule 454	Liquid	200 mg / mL	Oral	Le Naturiste J.M.B. Inc.	1980-12-31	2002-01-10
Magnesium Chloride 606.5mg	Tablet	606.5 mg	Oral	Bio Vita	1987-12-31	2006-07-27
Magnesium Liq 2.87mg/ml	Liquid	24 mg / mL	Oral	Vitalab	1990-12-31	2005-07-12
Magnesium Supplement	Solution	118.6 mg / 5 mL	Oral	Land Art Inc.	2003-07-21	2008-06-26
Magnesium-CL	Powder	119.6 mg / g	Oral	Vitavie Au Naturel 9023 3503 Quebec Inc.	1997-10-14	2009-07-29

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose	Magnesium chloride (25.5 mg / 100 mL) + Alanine (520 mg / 100 mL) + Arginine (290 mg / 100 mL) + Dextrose, unspecified form (10 g / 100 mL) + Dipotassium phosphate (130.5 mg / 100 mL) + Glycine (260 mg / 100 mL) + Histidine (120 mg / 100 mL) + Isoleucine (150 mg / 100 mL) + Leucine (182.5 mg / 100 mL) + Lysine hydrochloride (145 mg / 100 mL) + Methionine (100 mg / 100 mL) + Phenylalanine (140 mg / 100 mL) + Proline (170 mg / 100 mL) + Serine (125 mg / 100 mL) + Sodium acetate (170 mg / 100 mL) + Sodium chloride (29.3 mg / 100 mL) + Threonine (105 mg / 100 mL) + Tryptophan (45 mg / 100 mL) + Tyrosine (10 mg / 100 mL) + Valine (145 mg / 100 mL)	Solution	Intravenous	Baxter Corporation Clintec Nutrition Division	1996-12-31	2015-08-05
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix	Magnesium chloride (25.5 mg / 100 mL) + Alanine (520 mg / 100 mL) + Arginine (260 mg / 100 mL) + Dextrose, unspecified form (10 g / 100 mL) + Dipotassium phosphate (130.5 mg / 100 mL) + Glycine (520 mg / 100 mL) + Histidine (110 mg / 100 mL) + Isoleucine (120 mg / 100 mL) + L-Leucine hydrochloride (155 mg / 100 mL) + Lysine hydrochloride (145 mg / 100 mL) + Methionine (145 mg / 100 mL) + Phenylalanine hydrochloride (155 mg / 100 mL) + Proline (105 mg / 100 mL) + Sodium acetate (170 mg / 100 mL) + Sodium chloride (29.3 mg / 100 mL) + Threonine (105 mg / 100 mL) + Tryptophan (45 mg / 100 mL) + Tyrosine (10 mg / 100 mL) + Valine (115 mg / 100 mL)	Solution	Intravenous	Baxter Corporation Clintec Nutrition Division	1993-12-31	2015-08-05
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex	Magnesium chloride (25.5 mg / 100 mL) + Alanine (520 mg / 100 mL) + Arginine (290 mg / 100 mL) + Dextrose, unspecified form (25 g / 100 mL) + Dipotassium phosphate (130.5 mg / 100 mL) + Glycine (260 mg / 100 mL) + Histidine (120 mg / 100 mL) + Isoleucine (150 mg / 100 mL) + Leucine (182.5 mg / 100 mL) + Lysine hydrochloride (145 mg / 100 mL) + Methionine (100 mg / 100 mL) + Phenylalanine (140 mg / 100 mL) + Proline (170 mg / 100 mL) + Serine (125 mg / 100 mL) + Sodium acetate (170 mg / 100 mL) + Sodium chloride (29.3 mg / 100 mL) + Threonine (105 mg / 100 mL) + Tryptophan (45 mg / 100 mL) + Tyrosine (10 mg / 100 mL) + Valine (145 mg / 100 mL)	Liquid	Intravenous	Clintec Nutrition Company	1996-07-30	1998-08-13
2.75% Travas. Amino Acid InJ.W.elecw.25%dex	Magnesium chloride (51 mg / 100 mL) + Alanine (570 mg / 100 mL) + Arginine (316 mg / 100 mL) + Dextrose, unspecified form (25 g / 100 mL) + Dipotassium phosphate (261 mg / 100 mL) + Glycine (283 mg / 100 mL) + Histidine (132 mg / 100 mL) + Isoleucine (165 mg / 100 mL) + Leucine (201 mg / 100 mL) + Lysine hydrochloride (159.5 mg / 100 mL) + Methionine (110 mg / 100 mL) + Phenylalanine (154 mg / 100 mL) + Proline (187 mg / 100 mL) + Serine (137.5 mg / 100 mL) + Sodium acetate (215.5 mg / 100 mL) + Sodium chloride (112 mg / 100 mL) + Threonine (115.5 mg / 100 mL) + Tryptophan (49.5 mg / 100 mL) + Tyrosine (11 mg / 100 mL) + Valine (159.5 mg / 100 mL)	Liquid	Intravenous	Clintec Nutrition Company	1996-07-30	1998-08-13
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix	Magnesium chloride (51 mg / 100 mL) + Alanine (570 mg / 100 mL) + Arginine (285 mg / 100 mL) + Dextrose, unspecified form (25 g / 100 mL) + Dipotassium phosphate (261 mg / 100 mL) + Glycine (570 mg / 100 mL) + Histidine (120.5 mg / 100 mL) + Isoleucine (131.5 mg / 100 mL) + L-Leucine hydrochloride (170 mg / 100 mL) + Lysine hydrochloride (159 mg / 100 mL) + Methionine (159 mg / 100 mL) + Phenylalanine hydrochloride (170 mg / 100 mL) + Proline (115 mg / 100 mL) + Sodium acetate (215.5 mg / 100 mL) + Sodium chloride (112 mg / 100 mL) + Threonine (115 mg / 100 mL) + Tryptophan (49.5 mg / 100 mL) + Tyrosine (11 mg / 100 mL) + Valine (126 mg / 100 mL)	Solution	Intravenous	Baxter Corporation Clintec Nutrition Division	1996-02-02	2007-08-02

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
BALANCE %1,5 GLIKOZ 1,25 MMOL / 1 KALSIYUM 2000 ML BIOFIN TORBA	Magnesium chloride hexahydrate (0.1017 g/L) + Calcium chloride dihydrate (0.1838 g/L) + D-glucose monohydrate (16.5 g/L) + Sodium lactate (3.925 g/L) + Sodium chloride (5.64 g/L)	Solution	Intraperitoneal	FRESENIUS MEDİKAL HİZMETLER A.Ş.	2013-01-29	Not applicable
BALANCE %1,5 GLIKOZ 1,25 MMOL / 1 KALSIYUM 2500 ML BIOFIN TORBA	Magnesium chloride hexahydrate (0.1017 g/L) + Calcium chloride dihydrate (0.1838 g/L) + D-glucose monohydrate (16.5 g/L) + Sodium lactate (3.925 g/L) + Sodium chloride (5.64 g/L)	Solution	Intraperitoneal	FRESENIUS MEDİKAL HİZMETLER A.Ş.	2013-01-29	Not applicable
BALANCE %1,5 GLIKOZ 1,75 MMOL / 1 KALSIYUM 2000 ML BIOFIN TORBA	Magnesium chloride hexahydrate (0.1017 g/L) + Calcium chloride dihydrate (0.2573 g/L) + D-glucose monohydrate (16.5 g/L) + Sodium lactate (3.925 g/L) + Sodium chloride (5.64 g/L)	Solution	Intraperitoneal	FRESENIUS MEDİKAL HİZMETLER A.Ş.	2013-01-29	Not applicable
BALANCE %1,5 GLIKOZ 1,75 MMOL / 1 KALSIYUM 2500 ML BIOFIN TORBA	Magnesium chloride hexahydrate (0.1017 g/L) + Calcium chloride dihydrate (0.2573 g/L) + D-glucose monohydrate (16.5 g/L) + Sodium lactate (3.925 g/L) + Sodium chloride (5.64 g/L)	Solution	Intraperitoneal	FRESENIUS MEDİKAL HİZMETLER A.Ş.	2013-01-29	Not applicable
BALANCE %2,3 GLIKOZ 1,25 MMOL / 1 KALSIYUM 2000 ML BIOFIN TORBA	Magnesium chloride hexahydrate (0.1017 g/L) + Calcium chloride dihydrate (0.1838 g/L) + D-glucose monohydrate (25 g/L) + Sodium lactate (3.925 g/L) + Sodium chloride (5.64 g/L)	Solution	Intraperitoneal	FRESENIUS MEDİKAL HİZMETLER A.Ş.	2013-01-29	Not applicable

Categories

ATC Codes

A12CC01 — Magnesium chloride

• A12CC — Magnesium
• A12C — OTHER MINERAL SUPPLEMENTS
• A12 — MINERAL SUPPLEMENTS
• A — ALIMENTARY TRACT AND METABOLISM

B05XA11 — Magnesium chloride

• B05XA — Electrolyte solutions
• B05X — I.V. SOLUTION ADDITIVES
• B05 — BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
• B — BLOOD AND BLOOD FORMING ORGANS

Drug Categories

• Agents that produce neuromuscular block (indirect)
• Alimentary Tract and Metabolism
• Blood and Blood Forming Organs
• Blood Substitutes and Perfusion Solutions
• Chlorides
• Chlorine Compounds
• Drugs that are Mainly Renally Excreted
• Electrolyte Solutions
• Hemodialysis Solution
• I.V. Solution Additives
• Magnesium Compounds
• Metal cations
• Metal divalent cations
• Mineral Supplements
• Minerals

Chemical TaxonomyProvided by Classyfire

Description

This compound belongs to the class of inorganic compounds known as alkaline earth metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a lanthanide.

Kingdom

Inorganic compounds

Super Class

Mixed metal/non-metal compounds

Class

Alkaline earth metal salts

Sub Class

Alkaline earth metal chlorides

Direct Parent

Alkaline earth metal chlorides

Alternative Parents

Inorganic chloride salts

Substituents

Alkaline earth metal chloride / Inorganic chloride salt / Inorganic salt

Molecular Framework

Not Available

External Descriptors

inorganic chloride, magnesium salt, magnesium halide (CHEBI:6636)

Affected organisms

Not Available

Chemical Identifiers

UNII

59XN63C8VM

CAS number

7786-30-3

InChI Key

TWRXJAOTZQYOKJ-UHFFFAOYSA-L

InChI

InChI=1S/2ClH.Mg/h2*1H;/q;;+2/p-2

IUPAC Name

magnesium(2+) dichloride

SMILES

[Mg++].[Cl-].[Cl-]

References

General References

1. DRUGS.COM [Link]
2. Pubchem [Link]
3. Toxnet [Link]
4. ChemIDplus [Link]

External Links

KEGG Compound

C07755

PubChem Compound

5360315

PubChem Substance

347827844

ChemSpider

22987

RxNav

1311539

ChEBI

6636

ChEMBL

CHEMBL2219642

Wikipedia

Magnesium_chloride

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">

Phase	Status	Purpose	Conditions	Count
4	Completed	Treatment	APD / Continuous ambulatory peritoneal dialysis therapy / Diabetes / End Stage Renal Disease (ESRD)	1
4	Completed	Treatment	Chronic Kidney Disease (CKD) / Peritoneal dialysis therapy	1
4	Completed	Treatment	Hypovolaemia	1
4	Completed	Treatment	Impaired Renal Function	1
4	Completed	Treatment	Peritoneal Membrane Disorder / Renal Failure, Chronic Renal Failure	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Solution	Hemodialysis	0.257 g/1000ml
Solution	Intravenous	10.50 g/1000ml
Solution	Irrigation; Parenteral
Powder, for solution	Intraocular
Solution	Intraocular
Solution	Ophthalmic
Solution	Hemodialysis; Intravenous
Solution	Hemodialysis; Intravenous	0.187 g/L
Concentrate; kit; solution	Ophthalmic
Kit; solution	Intraocular
Solution	Intraperitoneal	0.2573 g/l
Solution	Intraperitoneal	0.1838 g/L
Solution
Solution	Intra-arterial
Suppository	Rectal	100 mg / sup
Injection, solution	Parenteral
Solution	Irrigation
Injection	Other
Injection	Other	16 mmol/20ml
Solution	Intraperitoneal
Solution	Intraperitoneal; Irrigation
Solution	Intraperitoneal	1.500 g
Injection, solution	Intraperitoneal
Solution	Intravenous	4.21 g/1000ml
Solution	Oral
Solution	Intrathecal
Solution	Intravenous; Subcutaneous
Solution	Intraperitoneal	25.7 mg/100ml
Powder	Oral
Liquid	Oral	200 mg / mL
Solution, concentrate	Hemodialysis
Spray	Oral
Aerosol, spray	Oral
Solution	Hemodialysis
Solution	Hemodialysis	7.77 g/l
Solution	Hemodialysis	8.46 g/l
Solution	Hemodialysis	8.8 g/l
Solution	Hemodialysis	8.85 g/l
Liquid	Hemodialysis
Solution	Hemodialysis	6.77 g/l
Liquid	Intraperitoneal
Solution	Hemodialysis; Intraperitoneal
Liquid	Intraocular
Solution	Intravenous
Patch	Topical
Injection, solution	Parenteral
Injection	Intravenous	200 mg/1mL
Injection, solution	Intravenous	200 mg/1mL
Tablet, coated	Oral
Tablet	Oral	606.5 mg
Tablet, delayed release	Oral	598 mg/1
Powder, for solution	Hemodialysis	5.15 g / vial
Liquid	Oral	24 mg / mL
Solution	Oral	118.6 mg / 5 mL
Powder, for solution	Hemodialysis	8 g / pck
Powder, for solution	Hemodialysis	16 g / pck
Powder	Hemodialysis	8.4 g / pck
Powder	Hemodialysis	16.8 g / pck
Powder, for solution	Hemodialysis	20.5 g / 4.5 L
Liquid	Oral	23.92 mg / mL
Powder	Oral	119.6 mg / g
Liquid	Oral	1 g / 5 mL
Tablet	Oral
Solution	Intravenous	15.220 g
Liquid	Buccal
Spray	Buccal
Solution	Intravenous	4.410 g
Injection, solution	Hemodialysis; Intravenous
Liquid	Intravenous
Tablet	Oral	36 mg / tab
Kit; solution	Intraocular; Irrigation
Solution	Intraperitoneal	2.500 g
Injection, emulsion; injection, solution	Intravenous
Injection, solution, concentrate	Intravenous
Solution	Intraperitoneal	0.184 g/l
Emulsion	Intravenous
Emulsion	Intravenous	4 g
Solution	Intraocular; Ophthalmic
Solution	Extracorporeal; Intrabiliary; Intracardiac
Emulsion	Parenteral
Emulsion	Intravenous	3 g
Injection, emulsion	Intravenous
Irrigant	Irrigation
Injection, solution	Intravenous
Injection	Intravenous	30 mg/100ml
Injection, solution	Intra-arterial
Solution	Hemodialysis; Intravenous	0.27 g/l
Kit	Hemodialysis
Solution	Hemodialysis	0.257 g/l
Solution	Buccal; Oral; Topical
Aerosol	Oral
Tablet, delayed release	Oral	64 mg / ect
Solution	Oral	11.700 mg
Solution	Parenteral	1.500 g
Solution	Parenteral	2.500 g
Solution	Parenteral	25.700 mg
Solution	Intraocular; Irrigation
Solution	Oral	0.012 g
Solution	Extracorporeal
Concentrate	Intravenous drip
Solution	Parenteral
Solution	Intravenous	0.3675 g/1000ml
Injection	Intravenous
Liquid	Ophthalmic

Prices

Not Available

Patents

Patent Number	Pediatric Extension	Approved	Expires (estimated)	Region
US5945449	No	1999-08-31	2017-10-31
US7300674	No	2007-11-27	2023-03-04
US6077836	No	2000-06-20	2017-06-20
US6248726	No	2001-06-19	2018-06-19
US7084130	No	2006-08-01	2021-11-29

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	19.3 mg/mL	ALOGPS
logP	1.16	ALOGPS
logP	-0.57	Chemaxon
logS	-0.69	ALOGPS
pKa (Strongest Acidic)	3.09	Chemaxon
Physiological Charge	2	Chemaxon
Hydrogen Acceptor Count	0	Chemaxon
Hydrogen Donor Count	0	Chemaxon
Polar Surface Area	0 Å2	Chemaxon
Rotatable Bond Count	0	Chemaxon
Refractivity	0 m3·mol-1	Chemaxon
Polarizability	1.78 Å3	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	Yes	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Not Available

Chromatographic Properties

Collision Cross Sections (CCS)

Not Available

×

Identify potential medication risks

Easily compare up to 40 drugs with our drug interaction checker.

Get severity rating, description, and management advice.

Learn more

Drug created at November 30, 2015 19:10 / Updated at February 20, 2024 23:55