Albumin iodinated I-131 serum

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Albumin iodinated I-131 serum is a radiopharmaceutical diagnostic agent indicated for use in the determination of total blood and plasma volume and other diagnostic purposes.

Generic Name
Albumin iodinated I-131 serum
DrugBank Accession Number
DB09430
Background

Iodinated I-131 serum albumin is a radiopharmaceutical agent used for several diagnostic purposes, including the determination of body fluid volumes and the imaging of certain tissues.1

Type
Biotech
Groups
Approved
Biologic Classification
Protein Based Therapies
Blood factors
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • Albumin, blood serum, labeled with Iodine-131
  • Albumin, Iodinated I 131 serum
  • Albumin, Iodinated I-131 serum
  • Albumin,Iodinated I-131 serum
  • Albumin,Iodinated serum,I-131
  • Human albumin I-131
  • Human serum albumin I-131
  • Iodinated (131I) human serum albumin
  • Iodinated I 131 serum albumin
  • Iodinated I-131 serum albumin

Pharmacology

Indication

Iodinated I-131 albumin is indicated for use in determinations of total blood and plasma volumes, cardiac output, cardiac and pulmonary blood volumes and circulation times, and in protein turnover studies, heart and great vessel delineation, localization of the placenta, and localization of cerebral neoplasms.1

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Not Available

Interactions

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Not Available
Food Interactions
Not Available

Products

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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
MegatopeInjection, solution1 mCi/1mLIntravenousIso-Tex Diagnostics, Inc.1996-05-21Not applicableUS flag
VolumexInjection, solution0.025 mCi/1mLIntravenousIso-Tex Diagnostics, Inc.1993-08-01Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
ACH35131L1
CAS number
Not Available

References

General References
  1. DailyMed: Megatope (iodinated I-131 albumin) for injection [Link]
RxNav
314301

Clinical Trials

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PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionIntravenous1 mCi/1mL
Injection, solutionIntravenous0.025 mCi/1mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at November 30, 2015 19:10 / Updated at October 06, 2020 17:43