Ferric ammonium citrate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

DrugBank Accession Number

DB09501

Background

Not Available

Type

Small Molecule

Groups

Approved, Experimental

Structure

Similar Structures

Weight: Average: 264.997
Monoisotopic: 264.986842
Chemical Formula: C₆H₁₁FeNO₇

Synonyms

Ferric ammonium citrate
Ferric ammonium citrate, green

External IDs

E 381
E-381
INS NO.381
INS-381

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Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">: Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Drug	Interaction
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Alendronic acid	Ferric ammonium citrate can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Almasilate	Almasilate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminium phosphate	Aluminium phosphate can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Aluminum hydroxide	Aluminum hydroxide can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Asenapine	Asenapine can cause a decrease in the absorption of Ferric ammonium citrate resulting in a reduced serum concentration and potentially a decrease in efficacy.

Food Interactions

No interactions found.

Products

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Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
Deriton	Ferric ammonium citrate (50 mg / 15 mL) + Choline bitartrate (50 mg / 15 mL) + Cyanocobalamin (14 mcg / 15 mL) + Dexpanthenol (5 mg / 15 mL) + Ergocalciferol (400 unit / 15 mL) + Inositol (50 mg / 15 mL) + Nicotinamide (45 mg / 15 mL) + Pyridoxine hydrochloride (2.5 mg / 15 mL) + Racemethionine (50 mg / 15 mL) + Riboflavin (5 mg / 15 mL) + Thiamine mononitrate (4.5 mg / 15 mL) + Vitamin A palmitate (5000 unit / 15 mL)	Liquid	Oral	Nutrimetics International (Canada) Inc.	1985-12-31	1996-09-09
Geritol Liquid	Ferric ammonium citrate (1 mg / mL) + Dexpanthenol (.34 mg / mL) + Nicotinamide (1 mg / mL) + Pyridoxine hydrochloride (.07 mg / mL) + Riboflavin (.17 mg / mL) + Thiamine hydrochloride (.1 mg / mL)	Liquid	Oral	Glaxosmithkline Inc	1992-12-31	2002-07-31
Heparos Ampoules Buvables	Ferric ammonium citrate (4.2 mg / 10 mL) + Cyanocobalamin (50 mcg / 10 mL)	Liquid	Oral	Desbergers LtÉe, Division Of Technilab Inc.	1987-12-31	1999-09-17
Iron, Vit & Min Supp	Ferric ammonium citrate (30 mg / tab) + Choline bitartrate (82 mg / tab) + Copper gluconate (1 mg / tab) + Cyanocobalamin (14 mcg / tab) + D-alpha-Tocopherol acetate (10 unit / tab) + Folic acid (.1 mg / tab) + Niacin (2.5 mg / tab) + Nicotinamide (7.5 mg / tab) + Pantothenic acid (5 mg / tab) + Pyridoxine (1.5 mg / tab) + Riboflavin (1.2 mg / tab) + Thiamine (1 mg / tab)	Tablet	Oral	Avacare, Division Of Jeunique International Inc.	1985-12-31	1996-09-09
Maltlevol 12 Liq	Ferric ammonium citrate (2.4 mg / mL) + Cyanocobalamin (.311 mcg / mL) + Nicotinamide (.667 mg / mL) + Pyridoxine (.067 mg / mL) + Riboflavin (.067 mg / mL) + Thiamine (.1 mg / mL) + Vitamin A (133 unit / mL) + Vitamin D (8.9 unit / mL) + Vitamin E (.56 unit / mL)	Liquid	Oral	Carter Horner Corp.	1978-12-31	2002-02-07

Chemical Identifiers

UNII: UVP74NG1C5
CAS number: 1185-57-5
InChI Key: FRHBOQMZUOWXQL-UHFFFAOYSA-N
InChI: InChI=1S/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;
IUPAC Name: iron(3+) 2-hydroxypropane-1,2,3-tricarboxylic acid amine
SMILES: N.[Fe+3].OC(=O)CC(O)(CC(O)=O)C(O)=O

References

General References

Not Available

External Links

ChemSpider: 2006378
RxNav: 24897
Wikipedia: Ammonium_ferric_citrate

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Granule, effervescent
Syrup	Oral	250 mg/5ml
Tablet	Oral
Syrup	Oral
Liquid	Oral
Syrup	Oral	250 mg/15mL

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	106.0 mg/mL	ALOGPS
logP	-1.3	ALOGPS
logP	-1.3	Chemaxon
logS	-0.26	ALOGPS
pKa (Strongest Acidic)	3.05	Chemaxon
pKa (Strongest Basic)	-4.2	Chemaxon
Physiological Charge	-3	Chemaxon
Hydrogen Acceptor Count	7	Chemaxon
Hydrogen Donor Count	4	Chemaxon
Polar Surface Area	132.13 Å²	Chemaxon
Rotatable Bond Count	5	Chemaxon
Refractivity	35.62 m³·mol^-1	Chemaxon
Polarizability	15.51 Å³	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST): Not Available
Spectra: Not Available
Chromatographic Properties: Collision Cross Sections (CCS)
Not Available

Drug created at November 30, 2015 19:10 / Updated at May 21, 2021 10:21

Ferric ammonium citrate

Identification

Structure for Ferric ammonium citrate (DB09501)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra

Collision Cross Sections (CCS)