Streptococcus pneumoniae type 23f capsular polysaccharide antigen

Identification

Brand Names

Pneumovax 23, Prevnar 13, Vaxneuvance

Generic Name

Streptococcus pneumoniae type 23f capsular polysaccharide antigen

DrugBank Accession Number

DB10340

Background

Streptococcus pneumoniae type 23f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 23f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.

Type

Biotech

Groups

Approved, Investigational

Biologic Classification

Vaccines
Other vaccines

Synonyms

• pneumococcal capsular polysaccharide type 23F vaccine
• Pneumococcal polysaccharide serotype 23F

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Pharmacology

Indication

Not Available

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Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Used in combination to prevent	Pneumococcal infection		••••••••••••			•••••••••• ••••••••• ••••••••
Used in combination to prevent	Active pneumococcal infection	Combination Product in combination with: Streptococcus pneumoniae type 2 capsular polysaccharide antigen (DB10320)	••••••••••••

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Contraindications & Blackbox Warnings

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

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Not Available

Interactions

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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

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Food Interactions

Not Available

Products

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Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Apexxnar	Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 10a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 11a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 12f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 15b capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 µg/0.5ml) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 8 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 µg/0.5ml)	Injection, suspension	Intramuscular	Pfizer Europe Ma Eeig	2022-06-06	Not applicable
Apexxnar	Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 10a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 11a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 12f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 15b capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 µg/0.5ml) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 8 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 µg/0.5ml)	Injection, suspension	Intramuscular	Pfizer Europe Ma Eeig	2022-06-06	Not applicable
Apexxnar	Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 10a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 11a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 12f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 15b capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 µg/0.5ml) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 8 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 µg/0.5ml)	Injection, suspension	Intramuscular	Pfizer Europe Ma Eeig	2022-06-06	Not applicable
Apexxnar	Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 10a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 11a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 12f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 15b capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 µg/0.5ml) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 8 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 µg/0.5ml)	Injection, suspension	Intramuscular	Pfizer Europe Ma Eeig	2022-06-06	Not applicable
Apexxnar	Streptococcus pneumoniae type 23f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 1 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 10a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 11a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 12f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 14 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 15b capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 18c capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 19f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 4 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 5 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6a capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 6b capsular polysaccharide antigen (4.4 µg/0.5ml) + Streptococcus pneumoniae type 7f capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 8 capsular polysaccharide antigen (2.2 µg/0.5ml) + Streptococcus pneumoniae type 9v capsular polysaccharide antigen (2.2 µg/0.5ml)	Injection, suspension	Intramuscular	Pfizer Europe Ma Eeig	2022-06-06	Not applicable

Categories

Drug Categories

• Actively Acquired Immunity
• Inactivated Pneumococcal Vaccine

Classification

Not classified

Affected organisms

Not Available

Chemical Identifiers

UNII

PYD255827T

CAS number

Not Available

References

General References

Not Available

External Links

PubChem Substance

347910519

RxNav

854956

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">

Phase	Status	Purpose	Conditions	Count
4	Active Not Recruiting	Prevention	Invasive Pneumococcal Disease, Protection Against / Pneumococcal Infection / Streptococcus Pneumoniae Infections	1
4	Active Not Recruiting	Prevention	Plasma Cell Neoplasms	1
4	Completed	Basic Science	Aging / Pneumonia	1
4	Completed	Diagnostic	Crohn's Disease (CD)	1
4	Completed	Diagnostic	Immune Responses / Pneumonia / Streptococcus Pneumoniae	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Injection	Intramuscular	25 mcg/0.5ml
Injection, solution	Intramuscular; Subcutaneous
Solution	Intramuscular; Subcutaneous
Injection	Intramuscular; Subcutaneous	25 mcg/0.5ml
Injection, solution	Subcutaneous
Suspension	Intramuscular
Injection	Intramuscular
Injection, suspension	Intramuscular
Injection

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

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Drug created at December 01, 2015 20:03 / Updated at June 12, 2020 16:53