Identification
- Summary
Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns.
- Brand Names
- Allegra Cooling Relief Anti-itch, Anbesol Cold Sore Therapy, Mederma Advanced Scar
- Generic Name
- Allantoin
- DrugBank Accession Number
- DB11100
- Background
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets Label. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated Label. In human muscle, urate is oxidized to allantoin during such exercise Label. The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise Label.
More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. It is a major metabolic intermediate in most organisms. Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions 4. Allantoin has also demonstrated to ameliorate the wound healing process in some studies 1.
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Allantoin (DB11100)
- Weight
- Average: 158.1154
Monoisotopic: 158.043990078 - Chemical Formula
- C4H6N4O3
- Synonyms
- (2,5-Dioxo-4-imidazolidinyl)urea
- 2,5-Dioxo-4-imidazolidinyl-urea
- 4-ureido-2,5-imidazolidinedione
- 5-Ureido-2,4-imidazolidindione
- 5-Ureidohydantoin
- Alantoína
- Allantoin
- Glyoxyldiureide
- N-(2,5-Dioxo-4-imidazolidinyl)urea
Pharmacology
- Indication
Allantoin is commonly applied in a variety of topical vehicles or applications such as cosmetic creams, toothpastes, mouthwashes, shampoos, lipsticks, anti-acne products, and lotions 4 for the purpose of moisturizing skin, enhancing the smoothness of skin, stimulating the healing of wounds, and soothing irritated skin 4,Label.
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Scarring Combination Product in combination with: Onion (DB10548), Heparin (DB01109) •••••••••••• ••• - Associated Therapies
- Contraindications & Blackbox Warnings
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There is no well controlled and appropriate data that can formally substantiate the pharmacodynamic properties of allantoin Label. Nevertheless, ongoing studies suggest that allantoin possesses moisturizing and keratolytic effects, as well as abilities to increase the water content of the extracellular matrix and enhance the desquamation of upper layers of dead skin cells, all of which are activities that can promote cell proliferation and facilitate wound healing 1.
- Mechanism of action
There is no well controlled data that can formally substantiate the method of action Label. However, ongoing studies suggest that there may exist a histological wound healing profile induced by allantoin in rats that leads to the amelioration and fastening of the reestablishment of normal skin 1. This facilitation of wound healing is supported by observations that wounds inflicted to rat subjects to which topical allantoin preparations were applied histologically demonstrated increased vasodilation, presence of inflammatory exudates, number of inflammatory cells, angiogenesis, fibroblast proliferation, and increased collagen deposition when compared to rat subjects with wounds that did not receive any allantoin administration 1.
- Absorption
In studies on human subjects, a recovery of 19% and 34% of allantoin in the urine was observed but only in two individuals and only after the administration of massive doses of allantoin 5. After intravenous administration, recovery in the urine was practically quantitative with doses of 75 to 600 mgm in the human model 5. After 240 mgm, excretion continued for 72 hours in human subjects and the results were similar in regards to subcutaneous injection 5.
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
Uricase is the enzyme that possesses the functionality to convert uric acid to allantoin. Considering humans do not possess any endogenous uricase, uric acid is the only final breakdown product in the purine degradation of unwanted waste product purine nucleotides 5. The presence of allantoin in human urine is subsequently the result of non-enzymatic processes on uric acid with reactive oxygen species 3. Such non-enzymatic processes are consequently potentially suitable biomarkers for measuring oxidative stress in chronic illnesses and aging 3. Furthermore, as allantoin is found endogenously and is part of basic, natural metabolic pathways, no accumulation is expected of it Label. Additionally, allantoin is not believed to be metabolized to a measurable extent in humans and animals Label.
- Route of elimination
Urinary clearance is the predominant excretion route Label.
- Half-life
When studied in cattle, sheep, and horses, the half-life of allantoin is in the range of 1 to 2.5 hours Label.
- Clearance
Some studies suggest that the average renal clearance of allantoin in normal, healthy human subjects is approximately 123 cc per minute 2. It is generally agreed upon that exogenously administered allantoin is rapidly excreted Label.
- Adverse Effects
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No studies on repeated dose toxicity and reproductive toxicity have been submitted. Moreover, studies show that the tumor incidence in allantoin treated animals did not differ largely from that found in untreated controls. As a result, further or additional toxicity, mutagenicity, or carcinogenicity tests are not required in view of the endogenous nature of allantoin and the general lack of overall toxicity Label.
Finally, as allantoin is a normal component of the diet in humans and is a substance of endogenous origin present in the body of humans, it is generally recognized as being a safe substance for humans Label.
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAsparaginase Erwinia chrysanthemi The therapeutic efficacy of Allantoin can be increased when used in combination with Asparaginase Erwinia chrysanthemi. Asparaginase Escherichia coli The therapeutic efficacy of Allantoin can be increased when used in combination with Asparaginase Escherichia coli. Beclomethasone dipropionate The therapeutic efficacy of Allantoin can be increased when used in combination with Beclomethasone dipropionate. Carbamazepine The therapeutic efficacy of Allantoin can be increased when used in combination with Carbamazepine. Ciclesonide The therapeutic efficacy of Allantoin can be increased when used in combination with Ciclesonide. - Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 12 Hour Healing Ointment 0.5 g/100g Topical Skinfix, Inc. 2017-05-02 2020-01-03 US 
12 Hour Healing Ointment 0.5 g/100g Topical Canadian Custom Packaging Company 2017-05-02 2017-11-17 US 12 Hour Miracle Ointment 0.5 g/100g Topical Skinfix, Inc. 2015-05-23 2020-01-03 US 28 Remedy Aqua Brightening Peeling Gel 0.05 g/100mL Topical NoTS Co.,Ltd 2016-01-02 2018-12-01 US 3ce Fixer and Mascara Black Liquid 0.006 g/6.6g Topical Nanda Co., Ltd. 2016-08-20 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 3M Nexcare Cold Sore Treatment Allantoin (10 mg/1g) + Benzocaine (50 mg/1g) Ointment Topical 3M Company 2008-02-20 2015-09-30 US 4Jointz Allantoin (0.025 g/100g) + Eucalyptus oil (4 g/100g) + Tannic acid (5 g/100g) Cream Topical Arp(usa) Pty Ltd 2017-01-31 2018-04-05 US A.H.c Cotton 100 Mask Multi Peptide Allantoin (0.025 g/25mL) + Adenosine (0.01 g/25mL) + Nicotinamide (0.05 g/25mL) Patch Topical Carver Korea Co.,Ltd. 2017-09-20 2018-12-01 US A.H.c Cotton 100 Mask Skin Ceramide Allantoin (0.025 g/25mL) + Adenosine (0.01 g/25mL) + Nicotinamide (0.05 g/25mL) Patch Topical Carver Korea Co.,Ltd. 2017-09-05 2018-12-01 US A.H.c Cotton 100 Mask Soy Isoflavone Allantoin (0.025 g/25mL) + Adenosine (0.01 g/25mL) + Nicotinamide (0.05 g/25mL) Patch Topical Carver Korea Co.,Ltd. 2017-09-14 2018-12-01 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 28 Remedy Aqua Brightening Peeling Allantoin (0.05 g/100mL) Gel Topical NoTS Co.,Ltd 2016-01-02 2018-12-01 US 3ce Fixer and Mascara Black Allantoin (0.006 g/6.6g) Liquid Topical Nanda Co., Ltd. 2016-08-20 Not applicable US 3ce Fixer and Mascara Brown Allantoin (0.006 g/6.6g) Liquid Topical Nanda Co., Ltd. 2016-08-20 Not applicable US A.H.c Cotton 100 Mask Multi Peptide Allantoin (0.025 g/25mL) + Adenosine (0.01 g/25mL) + Nicotinamide (0.05 g/25mL) Patch Topical Carver Korea Co.,Ltd. 2017-09-20 2018-12-01 US A.H.c Cotton 100 Mask Skin Ceramide Allantoin (0.025 g/25mL) + Adenosine (0.01 g/25mL) + Nicotinamide (0.05 g/25mL) Patch Topical Carver Korea Co.,Ltd. 2017-09-05 2018-12-01 US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as imidazoles. These are compounds containing an imidazole ring, which is an aromatic five-member ring with two nitrogen atoms at positions 1 and 3, and three carbon atoms.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Azoles
- Sub Class
- Imidazoles
- Direct Parent
- Imidazoles
- Alternative Parents
- Isoureas / Propargyl-type 1,3-dipolar organic compounds / Carboximidamides / Azacyclic compounds / Organopnictogen compounds / Organooxygen compounds / Imines / Hydrocarbon derivatives
- Substituents
- Aliphatic heteromonocyclic compound / Azacycle / Carboximidamide / Carboximidic acid derivative / Hydrocarbon derivative / Imidazole / Imine / Isourea / Organic 1,3-dipolar compound / Organic nitrogen compound
- Molecular Framework
- Aliphatic heteromonocyclic compounds
- External Descriptors
- ureas, imidazolidine-2,4-dione (CHEBI:15676) / a small molecule (S-ALLANTOIN)
- Affected organisms
- Humans and other mammals
Chemical Identifiers
- UNII
- 344S277G0Z
- CAS number
- 97-59-6
- InChI Key
- POJWUDADGALRAB-UHFFFAOYSA-N
- InChI
- InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)
- IUPAC Name
- (2,5-dioxoimidazolidin-4-yl)urea
- SMILES
- NC(=O)NC1NC(=O)NC1=O
References
- General References
- Araujo LU, Grabe-Guimaraes A, Mosqueira VC, Carneiro CM, Silva-Barcellos NM: Profile of wound healing process induced by allantoin. Acta Cir Bras. 2010 Oct;25(5):460-6. [Article]
- FRIEDMAN M, MYERS SO, ABRAHM PM: Allantoin clearance as a measure of glomerular filtration rate in man. Proc Soc Exp Biol Med. 1947 Dec;66(3):522. [Article]
- Kand'ar R, Zakova P: Allantoin as a marker of oxidative stress in human erythrocytes. Clin Chem Lab Med. 2008;46(9):1270-4. doi: 10.1515/CCLM.2008.244. [Article]
- Thornfeldt C: Cosmeceuticals containing herbs: fact, fiction, and future. Dermatol Surg. 2005 Jul;31(7 Pt 2):873-80; discussion 880. [Article]
- Toxnet Toxicology Data Network: Allantoin [Link]
- TITCK Product Information: Noskar (allium cepa extract/allantoin/heparin sodium) topical gel [Link]
- External Links
- Human Metabolome Database
- HMDB0000462
- KEGG Drug
- D00121
- KEGG Compound
- C01551
- PubChem Substance
- 347911116
- ChemSpider
- 199
- 508
- ChEBI
- 15676
- ChEMBL
- CHEMBL593429
- Wikipedia
- Allantoin
- FDA label
- Download (115 KB)
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count 3 Unknown Status Treatment Postoperative paralytic ileus 1 2 Completed Treatment Epidermolysis Bullosa (EB) 1 2 Completed Treatment Leg Injuries and Disorders / Venous Leg Ulcer (VLU) 1 2 Recruiting Treatment Children, Adult / Impaired Glucose Tolerance 1 2, 3 Recruiting Treatment Diabetic Foot Ulcers (DFUs) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Ointment Topical 0.5 g/100g Liquid Topical 0.006 g/6.6g Ointment Topical 1 g/100g Solution Topical 0.02 mg/71 Solution Topical 0.03 mg/61 Cream Topical 0.1 g/50mL Cream Cutaneous 0.2 mg/20mL Powder, for solution Topical Paste, dentifrice Topical Aerosol, spray Topical 0.425 g/85g Oil Topical 1 g/108.48g Spray Topical 0.425 g/85g Gel Topical 0.5 g/100mL Gel Topical 0.15 g/30mL Cream Topical 0.0005 g/1mL Liquid Topical 0.001 g/1mL Cream Topical 0.8 mg/160mL Lotion Topical 0.8 mg/160mL Gel Topical 0.8 mg/160mL Shampoo Topical 1.5 mg/300mL Lotion Topical 1.5 g/300mL Shampoo Topical 1.5 g/300mL Liquid Topical 0.25 g/100mL Liquid Topical 0.50 g/100mL Liquid Topical 0.15 g/30mL Liquid Topical 0.25 g/50mL Liquid Topical 0.1 g/20mL Soap Topical 0.5 g/100g Liquid Topical 1.0 g/200mL Solution Topical 0.005 mg/181 Lotion Topical 0.4 mL/200mL Liquid Topical 0.004 mL/2mL Liquid Topical 0.5 g/100g Patch Topical 0.12 g/60g Elixir Topical Emulsion Topical 0.6 % Lotion Topical 0.25 g/250g Cream Cutaneous 0.2 g/40g Patch Topical 0.15 g/31 Gel Topical 0.15 g/31 Patch Topical 0.004 g/2.4g Emulsion Topical 0.1 g/100mL Patch Topical 0.2 g/40g Stick Topical 0.5 g/100g Salve Topical 5 mg/1g Liquid Topical 0.15 g/100mL Gel Topical 0.55 g/100g Paste, dentifrice Oral Gel Topical 0.75 g/75g Cream Topical 0.225 mg/45mL Cream Topical 0.65 mg/130mL Spray Topical 0.6 mg/120mL Cream Topical 0.22 mg/45mL Cream Topical 2 g/100g Patch Topical 0.5 1/25g Patch Topical 0.06 g/51 Liquid Topical 0.05 g/100mL Cream Topical 0.5 mg/100g Cream Topical 5 mg/1g Jelly Topical 0.5 g/100mL Cream Topical 50 mg/5g Lipstick Topical Gel Cutaneous Cream Topical 0.5 mL/100mL Cream Topical 0.5 g/100mL Gel Topical 0.2 g/5mL Powder Topical 0.02 g/50g Disc Topical Paste, dentifrice Dental Emulsion Topical 0.24 g/120mL Emulsion Topical Patch Topical 0.05 g/25mL Cream Topical 3.6 mL/60mL Lotion Topical 0.5 1/50mL Cream Topical 0.5 mg/100mL Gel Topical 0.05 g/100g Cream Topical 0.1 g/100g Cream Cutaneous Patch Topical 0.1 g/49g Shampoo Topical 6.0 g/300mL Lotion Topical 0.75 mg/150mL Gel Topical 2 % Lotion Topical 2 % Gel Topical 0.1 g/100mL Liquid Topical Liquid Topical 0.1 g/100mL Powder, dentifrice Oral Cream Topical 1 g/50g Spray Topical 0.3 g/60g Spray Topical 1.2 g/100g Tablet, soluble Topical 0.5 mg/100mg Liquid Topical 0.02 g/4mL Liquid Topical 0.19 g/100g Lotion Topical 0.5 g/100mL Cream Topical 0.1 g/100mL Powder Topical 0.44 mg/80mL Powder Topical 0.055 g/10g Gel Topical 0.8 g/100g Soap Topical 2.0 g/100g Liquid Topical 0.54 mg/90mL Solution Topical 0.96 g/120mL Spray Topical 0.8 g/100mL Solution Topical 0.96 mg/120mL Solution Topical Liquid Topical 0.1 g/10g Gel Topical 0.5 g/100g Ointment Topical .02 g/1g Cream Topical 10 mg/1g Solution Topical 0.04 g/5g Cream Topical 20 mg/1g Lotion Topical 3 g/600g Lotion Cutaneous 0.1 mL/20mL Soap Cutaneous; Topical 5 mg/1g Powder Topical 0.002 g/1g Solution Topical 0.25 g/205g Tablet Vaginal 0.2 1/1 Tablet Vaginal 0.11 1/600mg Tablet Vaginal 66 mg/600mg Liquid Topical 0.05 g/100g Cream Vaginal Gel Extracorporeal Stick Topical Gel Topical 51.0 mg/10mL Gel Topical 50 mg/10mL Gel Topical 0.00003 g/10mL Cream Topical 0.67 mg/135mL Cream Topical 0.25 mg/50mL Patch Topical 0.2 g/100g Cream Topical 1 g/100mL Gel Topical 10 mg/1mL Gel Topical 0.1 mg/1mL Gel Topical 1 g/100g Liquid Topical 1 g/100g Cream Topical Lotion Topical 0.55 % Spray Topical Patch Topical 0.17 mg/35mL Soap Topical 0.6 g/100g Liquid Topical 0.01 g/100mL Ointment Topical 1 % Gel Topical Cream Topical 0.075 g/15mL Liquid Topical 1 mg/30mL Liquid Topical 0.08 g/100mL Liquid Topical 0.75 mg/150mL Patch Topical 0.028 g/28g Spray Topical 0.3 mg/60mL Cream Topical 0.5 g/100g Liquid Ophthalmic Solution / drops Ophthalmic Liquid Topical 0.6 mg/30mL Liquid Topical 0.54 mg/30mL Soap Topical 0.55 g/110g Gel Topical 3 mg/1mL Liquid Topical 0.05 g/10mL Shampoo Topical 0.75 g/150mL Solution Topical 0.30 g/60mL Liquid Topical 0.025 g/5mL Liquid Topical 0.0005 g/1mL Soap Topical 1.30 g/100g Aerosol, foam Topical 1.25 mg/250mL Oil Topical 0.75 mg/150mL Gel Topical 5 mg/1g Solution Topical 0.1 g/100mL Emulsion Topical 0.002 g/1mL Cream Topical 1 mg/100mL Liquid Topical 2 g/100mL Aerosol, foam Topical 0.5 g/100mL Lotion Topical 0.1 mL/50mL Liquid Topical 0.2 g/100mL Lotion Topical 0.4 g/20mL Liquid Topical 0.02 mg/1mL Cloth Topical 0.2 g/23mL Liquid Topical 0.1 g/100g Powder Topical 0.007 g/0.7g Cloth Topical 0.75 mL/1mL Liquid Topical 1 g/100mL Gel Topical 0.05 g/100mL Cream Topical 0.25 g/50g Injection Topical Shampoo Topical 0.75 mg/150mL Solution Topical 0.3 mg/60mL Liquid Topical 0.025 mg/5mL Liquid Topical 0.3 g/100mL Solution Topical 0.175 mg/51 Patch Topical 0.16 g/32g Lotion Topical 0.1 g/100mL Gel Topical 0.00009 g/30mL Patch Topical 0.015 mg/101 Spray Topical 0.36 mg/60mL Spray Topical 0.1 g/100mL Cream Topical 0.0125 mg/25g Cream Topical 0.004 mg/20mL Cream Topical 0.0042 mg/21mL Soap Topical 0.05 g/100g Stick Topical 5 mg/1g Lotion Topical 0.5 mL/100 mL Cream Topical 5 mg/100mL Cream Topical 5 mg/1mL Lotion Topical 0.5 mL/100mL Cream Topical 1 g/100g Gel Topical 0.3 g/100g Cream Topical 0.005 mg/1g Gel Topical 10 mg/1g Cream Topical 1.5 g/300g Liquid Topical 0.48 mg/80mL Solution Topical 0.48 mg/80mL Cream Topical 0.2 g/100mL Emulsion Topical 0.02 g/100mL Cream Topical 0.02 g/100mL Liquid Topical 0.02 g/100mL Soap Cutaneous 5 mg/1g Lotion Topical 0.1 g/100g Cream Topical 7.5 mg/1mL Lotion / shampoo Topical 5.5 mg/1mL Emulsion Topical 0.55 % Shampoo Topical Gel Topical 5 mg/1mL Cream Topical 1.2 g/120mL Paste, dentifrice Dental 0.1 mg/100g Liquid Dental 0.2 g/100mL Cream Topical 0.28 mg/40mL Cream Topical 1 % Concentrate Topical 0.22 g/45mL Liquid Topical 0.075 g/15mL Liquid Topical 0.002 mg/1mL Cream Topical 0.000003 g/30mL Liquid Topical 0.002 g/1mL Kit Topical Ointment Topical Cream Topical 0.002 g/1g Liquid Topical 5 mg/1mL Solution Topical 1.9 mg/380mL Emulsion Topical 0.65 mg/130mL Cream Topical 0.15 mg/30mL Cream Topical 0.75 mg/150mL Cream Topical 0.1 mL/100mL Cream Topical 0.0075 g/25g Liquid Topical 0.5 g/100mL Liquid Topical 0.625 mg/125mL Liquid Topical 0.57 g/113g Liquid Topical 0.75 g/150g Patch Topical Cream Topical 0.51 % Powder Topical 0.3 mg/3g Powder Topical 0.003 g/3g Powder Topical 0.2 mg/2g Powder Topical Liquid Topical 0.1 mg/1mL Mouthwash Dental Gel, dentifrice Dental Cream Topical 0.0005 g/1g Powder Topical 0.0001 g/1g Lotion Topical Cream Topical 0.425 g/85mL Cream Topical 0.02 mg/1mL Gel Topical 5.5 g/1L - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 4.73 mg/mL ALOGPS logP -2 ALOGPS logP -2.4 Chemaxon logS -1.5 ALOGPS pKa (Strongest Acidic) 7.95 Chemaxon pKa (Strongest Basic) -3.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 113.32 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 32.02 m3·mol-1 Chemaxon Polarizability 12.89 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 133.521128 predictedDarkChem Lite v0.1.0 [M-H]- 119.82797 predictedDeepCCS 1.0 (2019) [M+H]+ 134.940328 predictedDarkChem Lite v0.1.0 [M+H]+ 123.662994 predictedDeepCCS 1.0 (2019) [M+Na]+ 134.665028 predictedDarkChem Lite v0.1.0 [M+Na]+ 132.27083 predictedDeepCCS 1.0 (2019)
Carriers
- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- No
- Actions
- Substrate
- General Function
- Serine-type endopeptidase inhibitor activity
- Specific Function
- Major thyroid hormone transport protein in serum.
- Gene Name
- SERPINA7
- Uniprot ID
- P05543
- Uniprot Name
- Thyroxine-binding globulin
- Molecular Weight
- 46324.12 Da
References
- CYTOMEL (liothyronine) FDA label [File]
Drug created at December 03, 2015 16:51 / Updated at February 20, 2024 23:55