Ferrous cysteine glycinate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Ferrous cysteine glycinate is an ingredient found in a variety of supplements and vitamins.

Brand Names
EnBrace HR, EnLyte
Generic Name
Ferrous cysteine glycinate
DrugBank Accession Number
DB11197
Background

Not Available

Type
Small Molecule
Groups
Approved
Structure
Weight
Average: 371.2
Monoisotopic: 370.990814
Chemical Formula
C8H17FeN3O6S2
Synonyms
  • Ferrous cysteine glycinate chelate (1:2:1)

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatPernicious anemiaCombination Product in combination with: Pyridoxal phosphate (DB00114), Flavin adenine dinucleotide (DB03147), NADH (DB00157), Cobamamide (DB11191), Folic acid (DB00158), Levomefolic acid (DB11256), 1,2-Docosahexanoyl-sn-glycero-3-phosphoserine (DB11318), Phosphatidyl serine (DB00144), Leucovorin (DB00650), Zinc ascorbate (DB14485), Magnesium ascorbate (DB14484), Betaine (DB06756), L-threonic acid (DB11192)••••••••••••••••••• •••••••• ••••
Used in combination to treatPernicious anemiaCombination Product in combination with: Folic acid (DB00158), L-threonic acid (DB11192), Zinc ascorbate (DB14485), Leucovorin (DB00650), Betaine (DB06756), 1,2-Docosahexanoyl-sn-glycero-3-phosphoserine (DB11318), Levomefolic acid (DB11256), Pyridoxal phosphate (DB00114), Phosphatidyl serine (DB00144), NADH (DB00157), Flavin adenine dinucleotide (DB03147), Magnesium ascorbate (DB14484), Cobamamide (DB11191)••••••••••••••••••• •••••••• ••••
Used in combination to preventVitamin b9 deficiencyCombination Product in combination with: Folic acid (DB00158), Phosphatidyl serine (DB00144), Pyridoxal phosphate (DB00114), Levomefolic acid (DB11256), 1,2-Docosahexanoyl-sn-glycero-3-phosphoserine (DB11318), Magnesium ascorbate (DB14484), Cobamamide (DB11191), NADH (DB00157), Flavin adenine dinucleotide (DB03147), Leucovorin (DB00650), Betaine (DB06756), L-threonic acid (DB11192), Zinc ascorbate (DB14485)••••••••••••••••••• •••••••• ••••
Associated Therapies
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Not Available

Interactions

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Not Available
Food Interactions
No interactions found.

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Active Moieties
NameKindUNIICASInChI Key
Ferrous cationionicGW89581OWR15438-31-0CWYNVVGOOAEACU-UHFFFAOYSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
PramLyteFerrous cysteine glycinate (13.6 mg/1) + 1,2-docosahexanoyl-sn-glycero-3-phosphoserine calcium (6.4 mg/1) + 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium (800 ug/1) + Betaine (500 ug/1) + Citric acid monohydrate (1.83 mg/1) + Cobamamide (50 ug/1) + Cocarboxylase (25 ug/1) + Escitalopram oxalate (10 mg/1) + Flavin adenine dinucleotide (25 ug/1) + Folic acid (1 mg/1) + Leucovorin (2.5 mg/1) + Levomefolate magnesium (7 mg/1) + Magnesium ascorbate (24 mg/1) + NADH (25 ug/1) + Phosphatidyl serine (12 mg/1) + Pyridoxal phosphate (25 ug/1) + Sodium citrate (3.67 mg/1) + Zinc ascorbate (1 mg/1)KitOralAllegis Pharmaceuticals, LLC2015-09-112016-01-04US flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
DermaNICFerrous cysteine glycinate (1.5 mg/1) + Acetylcysteine zinc (69.5 mg/1) + Chromium nicotinate (0.57 mg/1) + Folic acid (500 ug/1) + Hydroxocobalamin (15 ug/1) + Inositol nicotinate (328 mg/1) + Niacin (1.5 mg/1) + Nicotinamide (498 mg/1)TabletOralAllegis Pharmaceuticals, LLC2014-02-032016-12-01US flag
EnBrace HRFerrous cysteine glycinate (13.6 mg/1) + 1,2-docosahexanoyl-sn-glycero-3-phosphoserine calcium (6.4 mg/1) + 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium (800 ug/1) + Betaine (500 ug/1) + Cobamamide (50 ug/1) + Cocarboxylase (25 ug/1) + Flavin adenine dinucleotide (25 ug/1) + Folic acid (1 mg/1) + Magnesium L-threonate (1 mg/1) + Leucovorin (2.5 mg/1) + Levomefolate magnesium (5.23 mg/1) + Magnesium ascorbate (24 mg/1) + NADH (25 ug/1) + Phosphatidyl serine (12 mg/1) + Pyridoxal phosphate (25 ug/1) + Zinc ascorbate (1 mg/1)Capsule, delayed release pelletsOralJaymac Pharma2011-08-12Not applicableUS flag
Escavite DFerrous cysteine glycinate (6 mg/1) + Ascorbic acid (100 mg/1) + Beta carotene (2500 [iU]/1) + Biotin (45 ug/1) + Cholecalciferol (600 [iU]/1) + Cupric oxide (2 mg/1) + DL-alpha-Tocopherol (30 [iU]/1) + Folic acid (400 ug/1) + Hydroxocobalamin (6 ug/1) + Magnesium oxide (60 mg/1) + Niacin (20 mg/1) + Calcium pantothenate (10 mg/1) + Pyridoxine hydrochloride (2 mg/1) + Riboflavin (1.7 mg/1) + Sodium fluoride (0.25 mg/1) + Thiamine hydrochloride (1.5 mg/1) + Zinc oxide (15 mg/1)Tablet, chewableOralGM Pharmaceuticals, INC2014-03-032018-11-01US flag
Escavite LqFerrous cysteine glycinate (1 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Cyanocobalamin (0.9 ug/1mL) + D-alpha-Tocopherol acetate (7.5 [iU]/1mL) + Ferric pyrophosphate (5 mg/1mL) + Niacin (8 mg/1mL) + Pyridoxine hydrochloride (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Sodium fluoride (0.25 mg/1mL) + Thiamine hydrochloride (0.5 mg/1mL) + Vitamin A palmitate (1500 [iU]/1mL)LiquidOralGM Pharmaceuticals, INC2013-08-202018-10-03US flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
8B4OP7RK5N
CAS number
Not Available
InChI Key
NIBOCUPOPAKNJE-NVKWYWNSSA-L
InChI
InChI=1S/2C3H7NO2S.C2H5NO2.Fe/c2*4-2(1-7)3(5)6;3-1-2(4)5;/h2*2,7H,1,4H2,(H,5,6);1,3H2,(H,4,5);/q;;;+2/p-2/t2*2-;;/m00../s1
IUPAC Name
lambda2-iron(2+) (2R)-2-amino-3-sulfanylpropanoic acid 2-aminoacetic acid (2R)-2-amino-3-sulfanidylpropanoate
SMILES
[Fe++].NCC(O)=O.[H][C@](N)(CS)C(O)=O.[H][C@](N)(C[S-])C([O-])=O

References

General References
Not Available
ChemSpider
34987810
RxNav
1490797

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TabletOral
Capsule, liquid filledOral
Capsule, delayed release pelletsOral
Tablet, chewableOral
LiquidOral
KitOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility23.1 mg/mLALOGPS
logP-2.6ALOGPS
logP-2.8Chemaxon
logS-0.72ALOGPS
pKa (Strongest Acidic)2.35Chemaxon
pKa (Strongest Basic)9.05Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area66.15 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity39.8 m3·mol-1Chemaxon
Polarizability10.67 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54