Alcloxa
Star1
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Alcloxa
- DrugBank Accession Number
- DB11205
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved
- Structure
- Weight
- Average: 314.55
Monoisotopic: 313.9790533 - Chemical Formula
- C4H9Al2ClN4O7
- Synonyms
- Alcloxa
- Alcloxum
- Aluminium chlorohydroxyallantoinate
- Aluminum chlorhydroxy allantoinate
- Aluminum chlorohydroxy allantoinate
- Chlorhydroxyaluminum allantoinate
- Dialuminum tetrahydroxychloro allantoinate
- External IDs
- RC 173
- RC-173
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to manage Dental cavity Combination Product in combination with: Silicon dioxide (DB11132) ••• ••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Take after a meal. Alcloxa is an ingredient used in toothpaste and brushing teeth after each meal is recommended.
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Active Moieties
Name Kind UNII CAS InChI Key Allantoin unknown 344S277G0Z 97-59-6 POJWUDADGALRAB-UHFFFAOYSA-N - Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Exoden Cure Powder Powder 0.16 g/100g Topical Lifeon Corp. 2021-03-09 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 28tak Gum Care Tooth Alcloxa (0.12 g/120g) + Aminocaproic acid (0.12 g/120g) + Calcium phosphate, dibasic (0.12 g/120g) + Calcium carbonate (36.0 g/120g) Paste, dentifrice Oral Elmeditec Co.,Ltd 2018-07-01 Not applicable US Clean Breath Tooth Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g) Paste, dentifrice Dental K.Boeun Pharmaceutical Co.,Ltd. 2021-05-01 Not applicable US Clean Breath Tooth Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g) Paste, dentifrice Dental K.Boeun Pharmaceutical Co.,Ltd. 2021-01-01 Not applicable US Clean Breath Tooth Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g) Paste, dentifrice Dental K.Boeun Pharmaceutical Co.,Ltd. 2021-11-30 Not applicable US Divinetree Ssak Shark Kids Tooth Alcloxa (0.08 g/50g) + Silicon dioxide (6.50 g/50g) Paste, dentifrice Oral K.biocos 2019-11-01 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 28tak Gum Care Tooth Alcloxa (0.12 g/120g) + Aminocaproic acid (0.12 g/120g) + Calcium phosphate, dibasic (0.12 g/120g) + Calcium carbonate (36.0 g/120g) Paste, dentifrice Oral Elmeditec Co.,Ltd 2018-07-01 Not applicable US Clean Breath Tooth Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g) Paste, dentifrice Dental K.Boeun Pharmaceutical Co.,Ltd. 2021-05-01 Not applicable US Clean Breath Tooth Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g) Paste, dentifrice Dental K.Boeun Pharmaceutical Co.,Ltd. 2021-11-30 Not applicable US Clean Breath Tooth Alcloxa (0.06 g/100g) + Aminocaproic acid (0.06 g/100g) + Calcium phosphate, dibasic (0.07 g/100g) + Calcium carbonate (36 g/100g) Paste, dentifrice Dental K.Boeun Pharmaceutical Co.,Ltd. 2021-01-01 Not applicable US Divinetree Ssak Shark Kids Tooth Alcloxa (0.08 g/50g) + Silicon dioxide (6.50 g/50g) Paste, dentifrice Oral K.biocos 2019-11-01 Not applicable US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 18B8O9DQA2
- CAS number
- 1317-25-5
- InChI Key
- IMZDRXBSGZPLDE-UHFFFAOYSA-H
- InChI
- InChI=1S/C4H6N4O3.2Al.ClH.4H2O/c5-3(10)6-1-2(9)8-4(11)7-1;;;;;;;/h1H,(H5,5,6,7,8,9,10,11);;;1H;4*1H2/q;2*+3;;;;;/p-6
- IUPAC Name
- dialuminium(3+) 4-(carbamoylamino)-2,5-dioxoimidazolidin-1-ide chloride tetrahydroxide
- SMILES
- [OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Cl-].NC(=O)NC1NC(=O)[N-]C1=O
References
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Paste, dentifrice Oral Paste Topical Powder Topical 0.16 g/100g Paste Oral Paste, dentifrice Topical Cream Topical Gel, dentifrice Oral Paste, dentifrice Dental Liquid Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 2.35 mg/mL ALOGPS logP -1.4 ALOGPS logP -2.4 Chemaxon logS -2 ALOGPS pKa (Strongest Acidic) 7.95 Chemaxon pKa (Strongest Basic) -3.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 110.52 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 31.22 m3·mol-1 Chemaxon Polarizability 12.54 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54