This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Brand Names
- Irospan 24/6 Kit
- Generic Name
- Ferrous bisglycinate
- DrugBank Accession Number
- DB11210
- Background
Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional 2. It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Ferrous bisglycinate (DB11210)
- Weight
- Average: 203.963
Monoisotopic: 203.983343 - Chemical Formula
- C4H8FeN2O4
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAlendronic acid Ferrous bisglycinate can cause a decrease in the absorption of Alendronic acid resulting in a reduced serum concentration and potentially a decrease in efficacy. Almasilate Almasilate can cause a decrease in the absorption of Ferrous bisglycinate resulting in a reduced serum concentration and potentially a decrease in efficacy. Aluminium phosphate Aluminium phosphate can cause a decrease in the absorption of Ferrous bisglycinate resulting in a reduced serum concentration and potentially a decrease in efficacy. Aluminum hydroxide Aluminum hydroxide can cause a decrease in the absorption of Ferrous bisglycinate resulting in a reduced serum concentration and potentially a decrease in efficacy. Asenapine Asenapine can cause a decrease in the absorption of Ferrous bisglycinate resulting in a reduced serum concentration and potentially a decrease in efficacy. - Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Ferrous bisglycinate hydrochloride IW3QLZ8MRC 67972-33-2 JTLXXRNVKWTJHD-UHFFFAOYSA-L - Active Moieties
Name Kind UNII CAS InChI Key Iron unknown E1UOL152H7 7439-89-6 XEEYBQQBJWHFJM-UHFFFAOYSA-N Ferrous cation ionic GW89581OWR 15438-31-0 CWYNVVGOOAEACU-UHFFFAOYSA-N - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image TUGAL Ferrous bisglycinate (19 mg) + Ascorbic acid (42 mg) + Calcium carbonate (120 mg) + Cholecalciferol (440 IU) + Cobaltous sulfate heptahydrate (50 mcg) + Cupric sulfate (1 mg) + Cyanocobalamin (1.15 IU) + Doconexent (300 mg) + Folic acid (1 mg) + Icosapent (25 mg) + Magnesium sulfate (14 mg) + Manganese (1 mg) + Nicotinamide (8.189 mg) + Pantothenic acid (17.5 mg) + Potassium sulfate (8 mg) + Pyridoxine hydrochloride (1.05 mg) + Riboflavin (2.2 mg) + Sodium fluoride (90 mcg) + Sodium molybdate (51 mcg) + Thiamine mononitrate (2.5 mg) + Vitamin A palmitate (5610 IU) + Vitamin E (10.5 IU) + Zinc oxide (0.2 mg) Capsule, liquid filled Oral PROCAPS S.A. 2017-09-28 Not applicable Colombia 
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image FeRiva Ferrous bisglycinate (75 mg/1) + Ascorbic acid (175 mg/1) + Biotin (300 ug/1) + Cyanocobalamin (120 ug/1) + Folic acid (1 mg/1) Capsule Oral Avion Pharmaceuticals, Llc 2012-11-26 2014-11-30 US 
FeRiva FA Ferrous bisglycinate (36.7 mg/1) + Ascorbic acid (175 mg/1) + Biotin (300 ug/1) + Cupric oxide (1.5 mg/1) + Cyanocobalamin (12 ug/1) + Docusate sodium (50 mg/1) + Ferrous asparto glycinate (36.7 mg/1) + Ferrous fumarate (36.7 mg/1) + Folic acid (1 mg/1) Capsule, gelatin coated Oral Avion Pharmaceuticals, Llc 2015-01-01 Not applicable US FeRivaFA Ferrous bisglycinate (110 mg/1) + Ascorbic acid (175 mg/1) + Biotin (300 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (12 ug/1) + Docusate sodium (50 mg/1) + Folic acid (1 mg/1) Capsule, gelatin coated Oral Avion Pharmaceuticals, Llc 2014-01-02 2015-12-31 US Folet DHA Ferrous bisglycinate (38 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2700 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + D-alpha-Tocopherol acetate (18 [iU]/1) + Doconexent (350 mg/1) + Docusate sodium (50 mg/1) + Folic acid (1 mg/1) + Magnesium oxide (30 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (40 mg/1) + Riboflavin (3.4 mg/1) + Selenium (65 ug/1) + Thiamine hydrochloride (3 mg/1) + Zinc glycinate (10 mg/1) Capsule, liquid filled; Kit; Tablet Oral Pronova Corporation 2014-08-28 2017-03-15 US healthy mamaBE WELL ROUNDED BE WELL ROUNDED Ferrous bisglycinate (28 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (4000 [iU]/1) + Biotin (30 ug/1) + Calcium carbonate (200 mg/1) + Cholecalciferol (400 [iU]/1) + Copper (2 mg/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Folic acid (800 ug/1) + Magnesium oxide (30 mg/1) + Mecobalamin (8 ug/1) + Niacin (20 mg/1) + Calcium pantothenate (10 mg/1) + Pyridoxine hydrochloride (2.6 mg/1) + Riboflavin (1.7 mg/1) + Thiamine chloride (1.8 mg/1) + Zinc oxide (25 mg/1) Tablet, film coated Oral MATERNAL SCIENCE, LLC 2013-07-09 Not applicable US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Carboxylic acids and derivatives
- Sub Class
- Amino acids, peptides, and analogues
- Direct Parent
- Alpha amino acids
- Alternative Parents
- Carboxylic acid salts / Amino acids / Organic transition metal salts / Monocarboxylic acids and derivatives / Carboxylic acids / Organic zwitterions / Organic oxides / Monoalkylamines / Hydrocarbon derivatives / Carbonyl compounds
- Substituents
- Aliphatic acyclic compound / Alpha-amino acid / Amine / Amino acid / Carbonyl group / Carboxylic acid / Carboxylic acid salt / Hydrocarbon derivative / Monocarboxylic acid or derivatives / Organic nitrogen compound
- Molecular Framework
- Not Available
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- SFW1D987QV
- CAS number
- 20150-34-9
- InChI Key
- GIPOFCXYHMWROH-UHFFFAOYSA-L
- InChI
- InChI=1S/2C2H5NO2.Fe/c2*3-1-2(4)5;/h2*1,3H2,(H,4,5);/q;;+2/p-2
- IUPAC Name
- lambda2-iron(2+) ion bis(2-aminoacetate)
- SMILES
- [Fe++].NCC([O-])=O.NCC([O-])=O
References
- General References
- Milman N, Jonsson L, Dyre P, Pedersen PL, Larsen LG: Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial. J Perinat Med. 2014 Mar;42(2):197-206. doi: 10.1515/jpm-2013-0153. [Article]
- Ashmead SD: The chemistry of ferrous bis-glycinate chelate. Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):7-12. [Article]
- External Links
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral Capsule, gelatin coated Oral Capsule, liquid filled; kit; tablet Oral Tablet, film coated Oral Kit; tablet; tablet, film coated Oral Capsule, gelatin coated; kit; tablet Oral Kit Oral Tablet Oral Capsule; kit; tablet, film coated Oral Capsule, liquid filled Oral Tablet, coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 211.0 mg/mL ALOGPS logP -1.5 ALOGPS logP -3.4 Chemaxon logS 0.02 ALOGPS pKa (Strongest Acidic) 2.31 Chemaxon pKa (Strongest Basic) 9.24 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 66.15 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 26.84 m3·mol-1 Chemaxon Polarizability 6.25 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 03, 2015 16:51 / Updated at September 28, 2021 21:54