Glyceryl monostearate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

DrugBank Accession Number

DB11250

Background

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.

Type

Small Molecule

Groups

Experimental

Structure

Similar Structures

Weight: Average: 358.5558
Monoisotopic: 358.308309832
Chemical Formula: C₂₁H₄₂O₄

Synonyms

Geleol mono and diglycerides
Glycerin monostearate
Glycerol monostearate
Glyceroli monostearas
Glyceryl monooctadecanoate
Glyceryl monopalmitostearate
Glyceryl stearate
Monoglyceryl stearate
Monostearate (glyceride)
Monostearin
Stearic acid, monoester with glycerol
Stearoylglycerol

Poor quality drug data slowing you down?

Unlock 38% more drug discovery time and eliminate decision-making doubts with this one-stop guide to quality drug data.

Download eBook

Poor quality drug data slowing you down?

Download eBook

Pharmacology

Indication: Not Available
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings: Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
Adverse Effects: Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">: Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

Products

Drug product information from 10+ global regions

Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.

Access now

Access drug product information from over 10 global regions.

Access now

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
Banacos Cica Mask	Glyceryl monostearate (0.416 g/100g) + Allantoin (0.01 g/100g) + Ethanol (0.01 mL/100g)	Patch	Topical	Cleoslab Co.,Ltd	2020-07-16	Not applicable
Cho-A Care Lot 1%	Glyceryl monostearate (10 mg/50g) + Hydrocortisone (10 mg/50g)	Lotion	Topical	Cho-A Pharm.Co.,Ltd.	2019-10-25	Not applicable
Fresh Med Solution	Glyceryl monostearate (0.4 g/40mL) + Ethanol (1.6 g/40mL) + Glycerin (1.744 g/40mL)	Liquid	Topical	Atomy Co., Ltd.	2011-07-18	2017-12-01
Fresh Med Solution	Glyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL) + Glycerin (1.744 mL/40mL)	Liquid	Topical	ATOMY CO LTD	2011-07-01	2011-07-01
Fresh Med Solution	Glyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL)	Liquid	Topical	ATOMY CO LTD	2011-06-24	2011-06-24

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
Fresh Med Solution	Glyceryl monostearate (0.4 mL/40mL) + Ethanol (1.6 mL/40mL)	Liquid	Topical	ATOMY CO LTD	2011-06-24	2011-06-24
Mycellcare All in One Serum	Glyceryl monostearate (0.728 g/100mL) + Allantoin (0.145 g/100mL) + Glycerin (4.16 g/100mL) + Nicotinamide (2.8 g/100mL)	Liquid	Topical	PHARMACAL-INTERNATIONAL. CO., LTD	2017-08-16	Not applicable

Chemical Identifiers

UNII: 258491E1RZ
CAS number: 31566-31-1
InChI Key: VBICKXHEKHSIBG-UHFFFAOYSA-N
InChI: InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
IUPAC Name: 2,3-dihydroxypropyl octadecanoate
SMILES: CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

References

General References

Not Available

External Links

Human Metabolome Database: HMDB0031075
ChemSpider: 23095
RxNav: 1311155
ChEBI: 75555
ChEMBL: CHEMBL255696
Wikipedia: Glycerol_monostearate

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Patch	Topical
Lotion	Topical
Liquid	Topical

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.00108 mg/mL	ALOGPS
logP	6.73	ALOGPS
logP	5.97	Chemaxon
logS	-5.5	ALOGPS
pKa (Strongest Acidic)	13.62	Chemaxon
pKa (Strongest Basic)	-3	Chemaxon
Physiological Charge	0	Chemaxon
Hydrogen Acceptor Count	3	Chemaxon
Hydrogen Donor Count	2	Chemaxon
Polar Surface Area	66.76 Å²	Chemaxon
Rotatable Bond Count	20	Chemaxon
Refractivity	103.31 m³·mol^-1	Chemaxon
Polarizability	46.63 Å³	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	0	Chemaxon
Rule of Five	No	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
GC-MS Spectrum - EI-B	GC-MS	splash10-007k-9530000000-e7c8759540fb484bf4af
GC-MS Spectrum - GC-EI-TOF	GC-MS	splash10-0f6t-2910000000-94597a6f353acb356316
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	splash10-0596-3049000000-f2db4bb2b80b913984b8
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	splash10-066u-9074000000-b8fbf10e064e48310116
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	splash10-06e9-9070000000-38335f4f1039c8ea1472
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	splash10-00g3-9385000000-3b3559d0849687184856
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	splash10-053u-9580000000-55fbdec35255781e7d90
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	splash10-052f-9200000000-f30749edd12bf5eb2a23
Predicted 1H NMR Spectrum	1D NMR	Not Applicable
Predicted 13C NMR Spectrum	1D NMR	Not Applicable

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å²)	Source type	Source
[M-H]-	231.3163824	predicted	DarkChem Lite v0.1.0
[M-H]-	188.87633	predicted	DeepCCS 1.0 (2019)
[M+H]+	232.2132824	predicted	DarkChem Lite v0.1.0
[M+H]+	191.42664	predicted	DeepCCS 1.0 (2019)
[M+Na]+	229.4525824	predicted	DarkChem Lite v0.1.0
[M+Na]+	198.49011	predicted	DeepCCS 1.0 (2019)

Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53

Glyceryl monostearate

Identification

Structure for Glyceryl monostearate (DB11250)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra

Collision Cross Sections (CCS)