NAV

Platinum

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Platinum
DrugBank Accession Number
DB12257
Background

Platinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine Carcinoma, among others. Platinum has been investigated for the treatment and supportive care of Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Primary Cancer, Non Small Cell Lung Cancer, and Primary Peritoneal Carcinoma, among others.

Type
Small Molecule
Groups
Investigational
Structure
Similar Structures
Weight
Average: 195.084
Monoisotopic: 194.964774449
Chemical Formula
Pt
Synonyms
  • platino
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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interactions in your software
AmbroxolThe risk or severity of methemoglobinemia can be increased when Platinum is combined with Ambroxol.
ArticaineThe risk or severity of methemoglobinemia can be increased when Platinum is combined with Articaine.
BenzocaineThe risk or severity of methemoglobinemia can be increased when Platinum is combined with Benzocaine.
Benzyl alcoholThe risk or severity of methemoglobinemia can be increased when Platinum is combined with Benzyl alcohol.
BupivacaineThe risk or severity of methemoglobinemia can be increased when Platinum is combined with Bupivacaine.
Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous transition metal compounds
Sub Class
Not Available
Direct Parent
Homogeneous transition metal compounds
Alternative Parents
Not Available
Substituents
Homogeneous transition metal
Molecular Framework
Not Available
External Descriptors
elemental platinum (CHEBI:33400)
Affected organisms
Not Available

Chemical Identifiers

UNII
49DFR088MY
CAS number
7440-06-4
InChI Key
BASFCYQUMIYNBI-UHFFFAOYSA-N
InChI
InChI=1S/Pt
IUPAC Name
platinum
SMILES
[Pt]

References

General References
Not Available
Human Metabolome Database
HMDB0013671
PubChem Compound
23939
PubChem Substance
347828531
ChemSpider
22381
RxNav
1311280
ChEBI
33364
PharmGKB
PA150595617
Wikipedia
Platinum

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
PhaseStatusPurposeConditionsCount
4CompletedTreatmentNon-squamous Non-small-cell Lung Cancer (NSQ NSCLC)1
4Not Yet RecruitingTreatmentNon-Small Cell Lung Cancer (NSCLC)1
4RecruitingTreatmentHemophagocytic Syndrome (HPS) / NK/T-cell Lymphoma1
4RecruitingTreatmentNon-Small Cell Lung Cancer (NSCLC)1
4Unknown StatusTreatmentNon-Small Cell Lung Cancer (NSCLC)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.03Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity0 m3·mol-1Chemaxon
Polarizability1.78 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at October 20, 2016 21:44 / Updated at June 12, 2020 16:53