This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
BCG vaccine is a vaccine indicated in the prevention of tuberculosis and the treatment of non-invasive urothelial bladder cancer.
- Generic Name
- BCG vaccine
- DrugBank Accession Number
- DB12768
- Background
BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
- Type
- Biotech
- Groups
- Approved, Investigational
- Biologic Classification
- Vaccines
Attenuated - Synonyms
- Bacillus calmette-guerin live antigen, unspecified substrain
- Bacillus Calmette–Guérin (BCG) vaccine
- BCG
- BCG vaccine
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Non-invasive bladder urothelial carcinoma •••••••••••• •••••• ••••••• ••••••• ••• •••••••••• Prevention of Recurrent superficial bladder cancer •••••••••••• •••••••••• •••••••••• ••••••• •••••••••••• ••• ••••••••• •••••••••• ••••••••• •••••••• Prevention of Tuberculosis (tb) •••••••••••• ••••••••• Management of Urothelial carcinoma recurrent •••••••••••• •••••• ••••••• ••••••• ••• •••••••••• Treatment of Carcinoma in situ of urinary bladder •••••••••••• •••••••••• •••••••••• ••••••• •••••••••••• ••• ••••••••• •••••••••• ••••••••• •••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbacavir The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Abacavir. Abatacept The risk or severity of infection can be increased when BCG vaccine is combined with Abatacept. Acetic acid The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acetic acid. Acetyl sulfisoxazole The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acetyl sulfisoxazole. Acyclovir The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Acyclovir. - Food Interactions
- Not Available
Products
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Categories
- ATC Codes
- L03AX03 — Bcg vaccine
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 8VJE55B0VG
- CAS number
- Not Available
References
- General References
- External Links
- PubChem Substance
- 347911376
- 1344
- Wikipedia
- BCG_vaccine
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count 4 Active Not Recruiting Prevention Coronavirus as the Cause of Diseases Classified Elsewhere / Coronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus 1 4 Completed Basic Science Adverse Reaction to Vaccine / Heterologous Immunity / Morbidity;Infant / Mortality, Infant / Trained Immunity / Vaccine Reaction 1 4 Completed Diagnostic Tuberculosis (TB) 1 4 Completed Prevention Absenteeism / Coronavirus Disease 2019 (COVID‑19) / Morbidity 1 4 Completed Prevention BCG Infection / Immune Responses / Vaccine Reaction 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Solution Intravesical 30 mg Powder, for solution Intravesical 1600000000 U Powder, for suspension Intravesical 1600000000 units Powder, for suspension Intravesical Injection, powder, lyophilized, for solution Intravesical Injection, powder, for suspension Intradermal Powder Intravesical Injection, powder, lyophilized, for solution Intravesical 81 mg Injection, powder, lyophilized, for solution Intradermal 500,000 CFU/0.1ml Injection Intradermal 0.1 ml Injection, powder, lyophilized, for suspension Intravesical 40 mg/ml Injection, powder, for solution Intravesical Injection Intradermal 81 mg/1vial - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at October 21, 2016 00:07 / Updated at June 12, 2021 10:54