Tuaminoheptane

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Tuaminoheptane is a vasoconstrictor nasal decongestant.

Generic Name
Tuaminoheptane
DrugBank Accession Number
DB13238
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 115.22
Monoisotopic: 115.136099551
Chemical Formula
C7H17N
Synonyms
  • 1-Methylhexylamine
  • 2-Aminoheptane
  • 2-Heptanamine
  • 2-Heptylamine
  • Tuaminoheptane
  • Tuaminoheptano
  • Tuaminoheptanum
External IDs
  • BRN 0635676

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatPurulent discharge acute rhinitisCombination Product in combination with: Acetylcysteine (DB06151)•••••••••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
OxymetazolineThe absorption of Tuaminoheptane can be decreased when combined with Oxymetazoline.
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Tuaminoheptane sulfateWZK5LN5CNW6411-75-2XKUUMWKWUZRRPD-UHFFFAOYSA-N
International/Other Brands
Heptadrine / Heptin / Tuamine

Categories

ATC Codes
R01AA11 — TuaminoheptaneR01AB08 — Tuaminoheptane
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as monoalkylamines. These are organic compounds containing an primary aliphatic amine group.
Kingdom
Organic compounds
Super Class
Organic nitrogen compounds
Class
Organonitrogen compounds
Sub Class
Amines
Direct Parent
Monoalkylamines
Alternative Parents
Organopnictogen compounds / Hydrocarbon derivatives
Substituents
Aliphatic acyclic compound / Hydrocarbon derivative / Organopnictogen compound / Primary aliphatic amine
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
Z0420GYD84
CAS number
123-82-0
InChI Key
VSRBKQFNFZQRBM-UHFFFAOYSA-N
InChI
InChI=1S/C7H17N/c1-3-4-5-6-7(2)8/h7H,3-6,8H2,1-2H3
IUPAC Name
heptan-2-amine
SMILES
CCCCCC(C)N

References

General References
  1. FDA Thailand Product Information: Rionfluimucil (tuaminoheptane sulfate/acetylcysteine) nasal spray [Link]
  2. AIFA: Rinofluimucil (Acetylcysteine, Tuaminoheptane) Nasal Spray [Link]
KEGG Drug
D07371
ChemSpider
5401
ChEBI
134753
ChEMBL
CHEMBL123693
Wikipedia
Tuaminoheptane

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SprayNasal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility3.29 mg/mLALOGPS
logP2.46ALOGPS
logP2Chemaxon
logS-1.5ALOGPS
pKa (Strongest Basic)10.43Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count1Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area26.02 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity37.41 m3·mol-1Chemaxon
Polarizability15.63 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-0006-9000000000-6a058b792df5f190f11d
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-0a4i-9100000000-d29b530794a6e5a1ce59
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-0a4i-9100000000-e52cdd7dc6b8ae3f42f6
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-0a4i-9000000000-129760657d3eebd06f29
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-0a4i-9000000000-0f570a9ae746619b17e8
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-0a4i-9000000000-f8d765d104e943737582
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-0a4i-9000000000-222514bf10edab79d8ee
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4i-9000000000-e0dc1a654c56a32e1939
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-0900000000-14793ff8b7374e8bb4d8
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0a4l-9000000000-1d13de08cfc3dd6790bf
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-5900000000-e23072a3a42bc15fadd8
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0006-9000000000-2c8a54ea3f626ec79945
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9000000000-82805701c943d0ecb86f
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-132.35893
predicted
DeepCCS 1.0 (2019)
[M+H]+134.45894
predicted
DeepCCS 1.0 (2019)
[M+Na]+143.09901
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:38 / Updated at June 05, 2021 09:13