Hydrochloric acid

Identification

Summary

Hydrochloric acid is a strong acid used to adjust the pH of injections and ophthalmic solutions.

Generic Name

Hydrochloric acid

DrugBank Accession Number

DB13366

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

3D

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MOLSDF3D-SDFPDBSMILESInChI

Similar Structures

Structure for Hydrochloric acid (DB13366)

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Weight

Average: 36.461
Monoisotopic: 35.976677739

Chemical Formula

ClH

Synonyms

• Chlorowodor
• Chlorure d'hydrogène
• Chlorwasserstoff
• Cloruro de hidrógeno
• Hydrochloric acid
• Hydrogenchlorid
• Wasserstoffchlorid

External IDs

• E-507
• INS NO.507
• INS-507
• NSC-77365

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Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

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Interactions

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Food Interactions

Not Available

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Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End	Region	Image
AMINOMIX	Hydrochloric acid (1.47 ml) + Acetic acid (4.5 g/1000ml) + Alanine (7 g/1000ml) + Arginine (6 g/1000ml) + Calcium chloride dihydrate (0.294 g/100ml) + Dextrose, unspecified form (120 g/100ml) + Glycine (5.5 g/1000ml) + Histidine (1.5 g/1000ml) + Isoleucine (2.5 g/1000ml) + Leucine (3.7 g/1000ml) + Lysine (3.3 g/1000ml) + Magnesium chloride hexahydrate (0.61 g/100ml) + Methionine (2.15 g/1000ml) + Phenylalanine (2.55 g/1000ml) + Potassium cation (30 mmol/l) + Potassium hydroxide (1.981 g/100ml) + Proline (5.6 g/1000ml) + Serine (3.25 g/1000ml) + Sodium cation (50 mmol/l) + Sodium chloride (1.169 g/100ml) + Sodium glycerophosphate hydrate (4.59 g/1000ml) + Taurine (0.5 g/1000ml) + Threonine (2.2 g/1000ml) + Tryptophan (1 g/1000ml) + Tyrosine (0.2 g/1000ml) + Valine (3.1 g/1000ml) + Zinc chloride (0.00545 g/100ml)	Injection, solution	Intravenous	Fresenius Kabi Italia S.R.L.	2014-07-08	Not applicable
AMINOMIX	Hydrochloric acid (1.47 ml) + Acetic acid (4.5 g/1000ml) + Alanine (7 g/1000ml) + Arginine (6 g/1000ml) + Calcium chloride dihydrate (0.294 g/100ml) + Dextrose, unspecified form (120 g/100ml) + Glycine (5.5 g/1000ml) + Histidine (1.5 g/1000ml) + Isoleucine (2.5 g/1000ml) + Leucine (3.7 g/1000ml) + Lysine (3.3 g/1000ml) + Magnesium chloride hexahydrate (0.61 g/100ml) + Methionine (2.15 g/1000ml) + Phenylalanine (2.55 g/1000ml) + Potassium cation (30 mmol/l) + Potassium hydroxide (1.981 g/100ml) + Proline (5.6 g/1000ml) + Serine (3.25 g/1000ml) + Sodium cation (50 mmol/l) + Sodium chloride (1.169 g/100ml) + Sodium glycerophosphate hydrate (4.59 g/1000ml) + Taurine (0.5 g/1000ml) + Threonine (2.2 g/1000ml) + Tryptophan (1 g/1000ml) + Tyrosine (0.2 g/1000ml) + Valine (3.1 g/1000ml) + Zinc chloride (0.00545 g/100ml)	Injection, solution	Intravenous	Fresenius Kabi Italia S.R.L.	2014-07-08	Not applicable
AMINOMIX	Hydrochloric acid (1.47 ml) + Acetic acid (4.5 g/1000ml) + Alanine (7 g/1000ml) + Arginine (6 g/1000ml) + Calcium chloride dihydrate (0.294 g/100ml) + Dextrose, unspecified form (200 g/100ml) + Glycine (5.5 g/1000ml) + Histidine (1.5 g/1000ml) + Isoleucine (2.5 g/1000ml) + Leucine (3.7 g/1000ml) + Lysine (3.3 g/1000ml) + Magnesium chloride hexahydrate (0.61 g/100ml) + Methionine (2.15 g/1000ml) + Phenylalanine (2.55 g/1000ml) + Potassium cation (30 mmol/l) + Potassium hydroxide (1.981 g/100ml) + Proline (5.6 g/1000ml) + Serine (3.25 g/1000ml) + Sodium cation (50 mmol/l) + Sodium chloride (1.169 g/100ml) + Sodium glycerophosphate hydrate (4.59 g/1000ml) + Taurine (0.5 g/1000ml) + Threonine (2.2 g/1000ml) + Tryptophan (1 g/1000ml) + Tyrosine (0.2 g/1000ml) + Valine (3.1 g/1000ml) + Zinc chloride (0.00545 g/100ml)	Injection, solution	Intravenous	Fresenius Kabi Italia S.R.L.	2014-07-08	Not applicable
AMINOMIX	Hydrochloric acid (1.47 ml) + Acetic acid (4.5 g/1000ml) + Alanine (7 g/1000ml) + Arginine (6 g/1000ml) + Calcium chloride dihydrate (0.294 g/100ml) + Dextrose, unspecified form (120 g/100ml) + Glycine (5.5 g/1000ml) + Histidine (1.5 g/1000ml) + Isoleucine (2.5 g/1000ml) + Leucine (3.7 g/1000ml) + Lysine (3.3 g/1000ml) + Magnesium chloride hexahydrate (0.61 g/100ml) + Methionine (2.15 g/1000ml) + Phenylalanine (2.55 g/1000ml) + Potassium cation (30 mmol/l) + Potassium hydroxide (1.981 g/100ml) + Proline (5.6 g/1000ml) + Serine (3.25 g/1000ml) + Sodium cation (50 mmol/l) + Sodium chloride (1.169 g/100ml) + Sodium glycerophosphate hydrate (4.59 g/1000ml) + Taurine (0.5 g/1000ml) + Threonine (2.2 g/1000ml) + Tryptophan (1 g/1000ml) + Tyrosine (0.2 g/1000ml) + Valine (3.1 g/1000ml) + Zinc chloride (0.00545 g/100ml)	Injection, solution	Intravenous	Fresenius Kabi Italia S.R.L.	2014-07-08	Not applicable
AMINOMIX	Hydrochloric acid (1.47 ml) + Acetic acid (4.5 g/1000ml) + Alanine (7 g/1000ml) + Arginine (6 g/1000ml) + Calcium chloride dihydrate (0.294 g/100ml) + Dextrose, unspecified form (120 g/100ml) + Glycine (5.5 g/1000ml) + Histidine (1.5 g/1000ml) + Isoleucine (2.5 g/1000ml) + Leucine (3.7 g/1000ml) + Lysine (3.3 g/1000ml) + Magnesium chloride hexahydrate (0.61 g/100ml) + Methionine (2.15 g/1000ml) + Phenylalanine (2.55 g/1000ml) + Potassium cation (30 mmol/l) + Potassium hydroxide (1.981 g/100ml) + Proline (5.6 g/1000ml) + Serine (3.25 g/1000ml) + Sodium cation (50 mmol/l) + Sodium chloride (1.169 g/100ml) + Sodium glycerophosphate hydrate (4.59 g/1000ml) + Taurine (0.5 g/1000ml) + Threonine (2.2 g/1000ml) + Tryptophan (1 g/1000ml) + Tyrosine (0.2 g/1000ml) + Valine (3.1 g/1000ml) + Zinc chloride (0.00545 g/100ml)	Injection, solution	Intravenous	Fresenius Kabi Italia S.R.L.	2014-07-08	Not applicable

Categories

ATC Codes

B05XA13 — Hydrochloric acid

• B05XA — Electrolyte solutions
• B05X — I.V. SOLUTION ADDITIVES
• B05 — BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
• B — BLOOD AND BLOOD FORMING ORGANS

A09AB03 — Hydrochloric acid

• A09AB — Acid preparations
• A09A — DIGESTIVES, INCL. ENZYMES
• A09 — DIGESTIVES, INCL. ENZYMES
• A — ALIMENTARY TRACT AND METABOLISM

Drug Categories

• Acid Preparations
• Acids
• Acids, Noncarboxylic
• Alimentary Tract and Metabolism
• Blood and Blood Forming Organs
• Blood Substitutes and Perfusion Solutions
• Chlorine Compounds
• Digestives, Incl. Enzymes
• Electrolyte Solutions
• I.V. Solution Additives

Chemical TaxonomyProvided by Classyfire

Description

This compound belongs to the class of inorganic compounds known as halogen hydrides. These are inorganic compounds in which the heaviest atom bonded to a hydrogen atom is a halogen.

Kingdom

Inorganic compounds

Super Class

Homogeneous non-metal compounds

Class

Halogen organides

Sub Class

Halogen hydrides

Direct Parent

Halogen hydrides

Alternative Parents

Inorganic hydrides

Substituents

Halogen hydride / Inorganic hydride

Molecular Framework

Not Available

External Descriptors

hydrogen halide, mononuclear parent hydride, chlorine molecular entity (CHEBI:17883) / a small molecule (HCL)

Affected organisms

Not Available

Chemical Identifiers

UNII

QTT17582CB

CAS number

7647-01-0

InChI Key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

InChI

InChI=1S/ClH/h1H

IUPAC Name

hydrogen chloride

SMILES

Cl

References

General References

Not Available

External Links

Human Metabolome Database

HMDB0002306

KEGG Drug

D02057

KEGG Compound

C01327

ChemSpider

307

RxNav

5486

ChEBI

17883

ChEMBL

CHEMBL1231821

Wikipedia

Hydrochloric_acid

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">

Phase	Status	Purpose	Conditions	Count
4	Completed	Treatment	Thyroid Eye Disease	1
2	Recruiting	Treatment	Efficacy of Ensatinib in This Subset of Patients / Second Generation ALK-TKI is Resistant / The Diagnosis Was ALK Positive NSCLC	1
Not Available	Recruiting	Treatment	Central Line Associated Blood Stream Infections (CLABSI)	1

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Injection, solution	Intravenous
Solution	Intravenous

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.0 mg/mL	ALOGPS
logP	-1.3	ALOGPS
logP	0.61	Chemaxon
logS	1.08	ALOGPS
pKa (Strongest Acidic)	-7	Chemaxon
Physiological Charge	-1	Chemaxon
Hydrogen Acceptor Count	0	Chemaxon
Hydrogen Donor Count	0	Chemaxon
Polar Surface Area	0 Å2	Chemaxon
Rotatable Bond Count	0	Chemaxon
Refractivity	6.42 m3·mol-1	Chemaxon
Polarizability	2.65 Å3	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	Yes	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted GC-MS Spectrum - GC-MS	Predicted GC-MS	splash10-000i-9000000000-9c67ad6c6de9138449dd
MS/MS Spectrum - Linear Ion Trap , negative	LC-MS/MS	splash10-0a4i-0000009000-8651ed5a563be0ad942f
MS/MS Spectrum - Linear Ion Trap , negative	LC-MS/MS	splash10-0a4i-0000009000-6193af2f15253417208c
MS/MS Spectrum - Linear Ion Trap , positive	LC-MS/MS	splash10-014i-0000900000-5818c00db6f91eb3e74d
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	splash10-000i-9000000000-a69f8335a8796781b4b0
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	splash10-001i-9000000000-c2fa753da65a4bac80a1
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	splash10-000i-9000000000-a69f8335a8796781b4b0
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	splash10-001i-9000000000-c2fa753da65a4bac80a1
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	splash10-000i-9000000000-a69f8335a8796781b4b0
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	splash10-001i-9000000000-c2fa753da65a4bac80a1

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å2)	Source type	Source
[M-H]-	112.116325	predicted	DeepCCS 1.0 (2019)
[M+H]+	113.84004	predicted	DeepCCS 1.0 (2019)
[M+Na]+	120.81027	predicted	DeepCCS 1.0 (2019)

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Drug created at June 23, 2017 20:40 / Updated at June 02, 2021 20:04