NAV

Sulfatolamide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Sulfatolamide
DrugBank Accession Number
DB13547
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Similar Structures
Weight
Average: 417.52
Monoisotopic: 417.059917634
Chemical Formula
C14H19N5O4S3
Synonyms
  • Sulfatolamide
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
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AcarboseThe therapeutic efficacy of Acarbose can be increased when used in combination with Sulfatolamide.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be increased when used in combination with Sulfatolamide.
AlbiglutideThe therapeutic efficacy of Albiglutide can be increased when used in combination with Sulfatolamide.
AlogliptinThe therapeutic efficacy of Alogliptin can be increased when used in combination with Sulfatolamide.
BenzylpenicillinSulfatolamide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.
Food Interactions
Not Available

Categories

ATC Codes
G01AE01 — Sulfatolamide
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzenesulfonamides
Direct Parent
Aminobenzenesulfonamides
Alternative Parents
Benzenesulfonyl compounds / Phenylmethylamines / Benzylamines / Aniline and substituted anilines / Aralkylamines / Organosulfonamides / Aminosulfonyl compounds / Organic oxides / Monoalkylamines / Hydrocarbon derivatives
Substituents
Amine / Aminobenzenesulfonamide / Aminosulfonyl compound / Aniline or substituted anilines / Aralkylamine / Aromatic homomonocyclic compound / Benzenesulfonyl group / Benzylamine / Hydrocarbon derivative / Organic nitrogen compound
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
3OLH2HAK9F
CAS number
1161-88-2
InChI Key
ZLYHTQKHXIVMLY-UHFFFAOYSA-N
InChI
InChI=1S/C7H9N3O2S2.C7H10N2O2S/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13;8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,8H2,(H3,9,10,13);1-4H,5,8H2,(H2,9,10,11)
IUPAC Name
(4-aminobenzenesulfonyl)thiourea; 4-(aminomethyl)benzene-1-sulfonamide
SMILES
NCC1=CC=C(C=C1)S(N)(=O)=O.NC(=S)NS(=O)(=O)C1=CC=C(N)C=C1

References

General References
Not Available
ChemSpider
2298573
ChEBI
32165
ChEMBL
CHEMBL3833354
Wikipedia
Sulfatolamide

Clinical Trials

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PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.344 mg/mLALOGPS
logP0.2ALOGPS
logP0.3Chemaxon
logS-2.8ALOGPS
pKa (Strongest Acidic)6.13Chemaxon
pKa (Strongest Basic)2.25Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area98.21 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity59.15 m3·mol-1Chemaxon
Polarizability21.76 Å3Chemaxon
Number of Rings2Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-191.05057
predicted
DeepCCS 1.0 (2019)
[M+H]+193.40858
predicted
DeepCCS 1.0 (2019)
[M+Na]+200.50298
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:44 / Updated at February 21, 2021 18:54