NAV

Heptaminol

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Heptaminol is a cardiac stimulant and vasodilator indicated in the treatment of hemorrhoids and venolymphatic insufficiency.

Generic Name
Heptaminol
DrugBank Accession Number
DB13574
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 145.246
Monoisotopic: 145.146664236
Chemical Formula
C8H19NO
Synonyms
  • Heptaminol
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Heptaminol hydrochlorideXB3RM40HIR543-15-7JZNBMCOSOXIZJB-UHFFFAOYSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
GINKOR FORT CAPSULEHeptaminol hydrochloride (300 mg) + Ginkgo biloba (14 mg) + Troxerutin (300 mg)CapsuleOralEP PLUS GROUP SDN. BHD.2020-09-08Not applicableMalaysia flag
จิงกอร์ ฟอร์ท(แคปซูล)Heptaminol (300 mg) + Ginkgo biloba (14 mg) + Troxerutin (300 mg)CapsuleOralบริษัท แปซิฟิค เฮลธ์แคร์ (ไทยแลนด์) จำกัด1999-04-26Not applicableThailand flag

Categories

ATC Codes
C01DX08 — Heptaminol
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as tertiary alcohols. These are compounds in which a hydroxy group, -OH, is attached to a saturated carbon atom R3COH (R not H ).
Kingdom
Organic compounds
Super Class
Organic oxygen compounds
Class
Organooxygen compounds
Sub Class
Alcohols and polyols
Direct Parent
Tertiary alcohols
Alternative Parents
Organopnictogen compounds / Monoalkylamines / Hydrocarbon derivatives
Substituents
Aliphatic acyclic compound / Amine / Hydrocarbon derivative / Organic nitrogen compound / Organonitrogen compound / Organopnictogen compound / Primary aliphatic amine / Primary amine / Tertiary alcohol
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
3DQS188SY5
CAS number
372-66-7
InChI Key
LREQLEBVOXIEOM-UHFFFAOYSA-N
InChI
InChI=1S/C8H19NO/c1-7(9)5-4-6-8(2,3)10/h7,10H,4-6,9H2,1-3H3
IUPAC Name
6-amino-2-methylheptan-2-ol
SMILES
CC(N)CCCC(C)(C)O

References

General References
  1. NPRA: Ginkor Fort (Ginkgo biloba, Heptaminol, Troxerutin) Oral Capsule [Link]
ChemSpider
3464
BindingDB
50101812
RxNav
5254
ChEBI
94362
ChEMBL
CHEMBL2111076
Wikipedia
Heptaminol

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Solution / dropsOral3.054 G
CapsuleOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility16.2 mg/mLALOGPS
logP1.31ALOGPS
logP0.82Chemaxon
logS-0.95ALOGPS
pKa (Strongest Acidic)18.53Chemaxon
pKa (Strongest Basic)10.43Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area46.25 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity43.8 m3·mol-1Chemaxon
Polarizability18.22 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-052f-9100000000-3fbfd029f8d905ba50ff
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-020r-9800000000-1baaa274488004622d92
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-0900000000-2ac64f531fb95662083f
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-3900000000-7b7d6ef2764936540a80
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-cdef409fa5f6866beb6c
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9100000000-36f4e41ef098c7907c8c
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-052f-9000000000-5f9960ac04d93059b041
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-136.84337
predicted
DeepCCS 1.0 (2019)
[M+H]+139.45082
predicted
DeepCCS 1.0 (2019)
[M+Na]+148.62315
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:44 / Updated at May 29, 2021 18:11