Metenolone

Identification

Summary

Metenolone is an anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes.

Generic Name

Metenolone

DrugBank Accession Number

DB13710

Background

Not Available

Type

Small Molecule

Groups

Experimental

Structure

3D

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MOLSDF3D-SDFPDBSMILESInChI

Similar Structures

Structure for Metenolone (DB13710)

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Weight

Average: 302.451
Monoisotopic: 302.224580204

Chemical Formula

C₂₀H₃₀O₂

Synonyms

• Metenolona
• Metenolone
• Methenolone

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Pharmacology

Indication

Not Available

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Associated Conditions

Indication Type	Indication	Combined Product Details	Approval Level	Age Group	Patient Characteristics	Dose Form
Management of	Catabolic state		••••••••••••			•••••••••• ••••••••

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Associated Therapies

• Steroid therapy

Contraindications & Blackbox Warnings

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Pharmacodynamics

Not Available

Mechanism of action

Not Available

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism

Not Available

Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects

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Toxicity

Not Available

Pathways

Not Available

Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">

Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">

This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drug	Interaction
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Beclomethasone dipropionate	The risk or severity of edema formation can be increased when Metenolone is combined with Beclomethasone dipropionate.
Betamethasone	The risk or severity of edema formation can be increased when Metenolone is combined with Betamethasone.
Betamethasone phosphate	The risk or severity of edema formation can be increased when Metenolone is combined with Betamethasone phosphate.
Budesonide	The risk or severity of edema formation can be increased when Metenolone is combined with Budesonide.
Ciclesonide	The risk or severity of edema formation can be increased when Metenolone is combined with Ciclesonide.

Food Interactions

Not Available

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Categories

ATC Codes

A14AA04 — Metenolone

• A14AA — Androstan derivatives
• A14A — ANABOLIC STEROIDS
• A14 — ANABOLIC AGENTS FOR SYSTEMIC USE
• A — ALIMENTARY TRACT AND METABOLISM

Drug Categories

• Alimentary Tract and Metabolism
• Anabolic Agents
• Anabolic Agents for Systemic Use
• Anabolic Steroids
• Androstan Derivatives
• Androstanes
• Androstenes
• Androstenols
• Fused-Ring Compounds
• Hormones
• Hormones, Hormone Substitutes, and Hormone Antagonists
• Steroids
• Testosterone Congeners

Chemical TaxonomyProvided by Classyfire

Description

This compound belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Steroids and steroid derivatives

Sub Class

Androstane steroids

Direct Parent

Androgens and derivatives

Alternative Parents

3-oxo-5-alpha-steroids / 3-oxo delta-1-steroids / 17-hydroxysteroids / Delta-1-steroids / Cyclohexenones / Secondary alcohols / Cyclic alcohols and derivatives / Organic oxides / Hydrocarbon derivatives

Substituents

17-hydroxysteroid / 3-oxo-5-alpha-steroid / 3-oxo-delta-1-steroid / 3-oxosteroid / Alcohol / Aliphatic homopolycyclic compound / Androgen-skeleton / Carbonyl group / Cyclic alcohol / Cyclic ketone

Molecular Framework

Aliphatic homopolycyclic compounds

External Descriptors

C19 steroids (androgens) and derivatives (LMST02020028)

Affected organisms

Not Available

Chemical Identifiers

UNII

9062ZT8Q5C

CAS number

153-00-4

InChI Key

ANJQEDFWRSLVBR-VHUDCFPWSA-N

InChI

InChI=1S/C20H30O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h10,13,15-18,22H,4-9,11H2,1-3H3/t13-,15-,16-,17-,18-,19-,20-/m0/s1

IUPAC Name

(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-hydroxy-9,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

SMILES

[H][C@]1(O)CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])CC(=O)C=C(C)[C@]4(C)[C@@]3([H])CC[C@]12C

References

General References

1. TITCK Product Information: Rimobolan (methenolone enanthate) solution for intramuscular injection [Link]

External Links

Human Metabolome Database

HMDB0041928

ChemSpider

2301378

RxNav

6833

ChEBI

135283

ZINC

ZINC000005497532

Wikipedia

Metenolone

Clinical Trials

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Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Solution	Intramuscular	100 mg/1ml

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	0.022 mg/mL	ALOGPS
logP	3.45	ALOGPS
logP	3.65	Chemaxon
logS	-4.1	ALOGPS
pKa (Strongest Acidic)	19.38	Chemaxon
pKa (Strongest Basic)	-0.88	Chemaxon
Physiological Charge	0	Chemaxon
Hydrogen Acceptor Count	2	Chemaxon
Hydrogen Donor Count	1	Chemaxon
Polar Surface Area	37.3 Å2	Chemaxon
Rotatable Bond Count	0	Chemaxon
Refractivity	88.98 m3·mol-1	Chemaxon
Polarizability	35.88 Å3	Chemaxon
Number of Rings	4	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	Yes	Chemaxon
Veber's Rule	Yes	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted GC-MS Spectrum - GC-MS	Predicted GC-MS	splash10-05g0-0290000000-541020c4a6431e6bc339
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	splash10-0udi-0069000000-2cdefc529141726addfe
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0udi-0009000000-6910ef310c48d110a3e1
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	splash10-001r-1691000000-eebd3003cfdacf9a07ee
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0udi-0009000000-079cc44920a32d9fa75f
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0f89-0094000000-fae6e4307f4e353ca337
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	splash10-0a4s-0910000000-b7fd76ae8d7bad0a26d9
Predicted 1H NMR Spectrum	1D NMR	Not Applicable
Predicted 13C NMR Spectrum	1D NMR	Not Applicable

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å2)	Source type	Source
[M-H]-	180.0524164	predicted	DarkChem Lite v0.1.0
[M-H]-	179.8735164	predicted	DarkChem Lite v0.1.0
[M-H]-	180.0345164	predicted	DarkChem Lite v0.1.0
[M-H]-	166.12024	predicted	DeepCCS 1.0 (2019)
[M+H]+	180.6803164	predicted	DarkChem Lite v0.1.0
[M+H]+	180.5445164	predicted	DarkChem Lite v0.1.0
[M+H]+	180.8578164	predicted	DarkChem Lite v0.1.0
[M+H]+	168.01566	predicted	DeepCCS 1.0 (2019)
[M+Na]+	180.3863164	predicted	DarkChem Lite v0.1.0
[M+Na]+	180.1315164	predicted	DarkChem Lite v0.1.0
[M+Na]+	180.0687164	predicted	DarkChem Lite v0.1.0
[M+Na]+	173.86295	predicted	DeepCCS 1.0 (2019)

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Drug created at June 23, 2017 20:47 / Updated at May 29, 2021 18:12