NAV

Cypermethrin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Cypermethrin is a medication used to treat parasitic skin diseases.

Generic Name
Cypermethrin
DrugBank Accession Number
DB13721
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 416.297
Monoisotopic: 415.074198893
Chemical Formula
C22H19Cl2NO3
Synonyms
Not Available
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Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Treatment ofSkin diseases, parasitic••••••••••••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

ATC Codes
P03BA02 — Cypermethrin
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as pyrethroids. These are organic compounds similar to the pyrethrins. Some pyrethroids containing a chrysanthemic acid esterified with a cyclopentenone (pyrethrins), or with a phenoxybenzyl group.
Kingdom
Organic compounds
Super Class
Lipids and lipid-like molecules
Class
Fatty Acyls
Sub Class
Fatty acid esters
Direct Parent
Pyrethroids
Alternative Parents
Diphenylethers / Diarylethers / Benzyloxycarbonyls / Phenoxy compounds / Phenol ethers / Cyclopropanecarboxylic acids and derivatives / Carboxylic acid esters / Ketene acetals / Chloroalkenes / Vinyl chlorides
show 7 more
Substituents
Aromatic homomonocyclic compound / Benzenoid / Benzyloxycarbonyl / Carbonitrile / Carbonyl group / Carboxylic acid derivative / Carboxylic acid ester / Chloroalkene / Cyclopropanecarboxylic acid or derivatives / Diaryl ether
show 21 more
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
aromatic ether, carboxylic ester, organochlorine compound, nitrile, cyclopropanes (CHEBI:4042) / Pyrethroid insecticides, Pyrethroid pesticides (C10984)
Affected organisms
Not Available

Chemical Identifiers

UNII
1TR49121NP
CAS number
52315-07-8
InChI Key
KAATUXNTWXVJKI-UHFFFAOYSA-N
InChI
InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3
IUPAC Name
cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
SMILES
CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1

References

General References
  1. INVIMA Product Authorization: Pioxan (cypermethrin) topical emulsion [Link]
KEGG Compound
C10984
ChemSpider
2809
RxNav
2590266
ChEBI
4042
ChEMBL
CHEMBL373204
Wikipedia
Cypermethrin

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
EmulsionTopical0.2 g
LotionTopical0.2 g
EmulsionTopical200 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000864 mg/mLALOGPS
logP5.81ALOGPS
logP5.44Chemaxon
logS-5.7ALOGPS
pKa (Strongest Acidic)10.65Chemaxon
pKa (Strongest Basic)-3.7Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area59.32 Å2Chemaxon
Rotatable Bond Count7Chemaxon
Refractivity119.09 m3·mol-1Chemaxon
Polarizability41.08 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Mass Spectrum (Electron Ionization)MSsplash10-02cr-4910000000-8849f1db9e07694cee2f
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-4146900000-fbcd7a99f64cabba672b
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-01p9-0910300000-1573349386861c0be94a
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-01q9-0912000000-f89a01b141b10cb74842
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0aor-6291200000-ba45df37078829e744fb
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-08fs-4988000000-386c680e6e34d44c57f3
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-067i-6893200000-9f01ab8ad46e7d3ffe0a
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-191.00954
predicted
DeepCCS 1.0 (2019)
[M+H]+193.36752
predicted
DeepCCS 1.0 (2019)
[M+Na]+200.0437
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:47 / Updated at May 22, 2021 06:01