NAV

Fazadinium bromide

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Fazadinium bromide
DrugBank Accession Number
DB13745
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Similar Structures
Weight
Average: 604.35
Monoisotopic: 602.042921
Chemical Formula
C28H24Br2N6
Synonyms
  • Fazadinium bromide
External IDs
  • AH 8165D
Poor quality drug data slowing you down?
Unlock 38% more drug discovery time and eliminate decision-making doubts with this one-stop guide to quality drug data.
Download eBook
Poor quality drug data slowing you down?
Download eBook

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Integrate drug-drug
interactions in your software
1,2-BenzodiazepineThe risk or severity of CNS depression can be increased when 1,2-Benzodiazepine is combined with Fazadinium bromide.
AcetazolamideThe risk or severity of CNS depression can be increased when Acetazolamide is combined with Fazadinium bromide.
AcetophenazineThe risk or severity of CNS depression can be increased when Acetophenazine is combined with Fazadinium bromide.
AgomelatineThe risk or severity of CNS depression can be increased when Agomelatine is combined with Fazadinium bromide.
AlfentanilThe risk or severity of CNS depression can be increased when Alfentanil is combined with Fazadinium bromide.
Food Interactions
Not Available

Categories

ATC Codes
M03AC08 — Fazadinium bromide
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as phenylimidazoles. These are polycyclic aromatic compounds containing a benzene ring linked to an imidazole ring through a CC or CN bond.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Azoles
Sub Class
Imidazoles
Direct Parent
Phenylimidazoles
Alternative Parents
Imidazopyridines / Imidazo[1,2-a]pyridines / Pyridinium derivatives / N-substituted imidazoles / Benzene and substituted derivatives / Heteroaromatic compounds / Azacyclic compounds / Organonitrogen compounds / Organic bromide salts / Hydrocarbon derivatives
show 1 more
Substituents
4-phenylimidazole / 5-phenylimidazole / Aromatic heteropolycyclic compound / Azacycle / Benzenoid / Heteroaromatic compound / Hydrocarbon derivative / Imidazo[1,2-a]pyridine / Imidazopyridine / Monocyclic benzene moiety
show 8 more
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
8WV5538LFK
CAS number
49564-56-9
InChI Key
LBOZSXSPRGACHC-NFOZGECASA-L
InChI
InChI=1S/C28H24N6.2BrH/c1-21-27(23-13-5-3-6-14-23)33(25-17-9-11-19-31(21)25)29-30-34-26-18-10-12-20-32(26)22(2)28(34)24-15-7-4-8-16-24;;/h3-20H,1-2H3;2*1H/q+2;;/p-2/b30-29+;;
IUPAC Name
3-methyl-1-[(E)-2-{3-methyl-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium-1-yl}diazen-1-yl]-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium dibromide
SMILES
[Br-].[Br-].CC1=C(N(\N=N\N2C3=CC=CC=[N+]3C(C)=C2C2=CC=CC=C2)C2=CC=CC=[N+]12)C1=CC=CC=C1

References

General References
Not Available
ChemSpider
4882031
ChEMBL
CHEMBL1697835
Wikipedia
Fazadinium_bromide

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00575 mg/mLALOGPS
logP0.96ALOGPS
logP-0.3Chemaxon
logS-5ALOGPS
pKa (Strongest Basic)-0.091Chemaxon
Physiological Charge2Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area42.78 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity142.88 m3·mol-1Chemaxon
Polarizability49.76 Å3Chemaxon
Number of Rings6Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-001i-0920000000-2c4f69445b1005b9b023
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-223.9009198
predicted
DarkChem Lite v0.1.0
[M-H]-193.95705
predicted
DeepCCS 1.0 (2019)
[M+H]+223.3743198
predicted
DarkChem Lite v0.1.0
[M+H]+196.28072
predicted
DeepCCS 1.0 (2019)
[M+Na]+223.9376198
predicted
DarkChem Lite v0.1.0
[M+Na]+202.0717
predicted
DeepCCS 1.0 (2019)

Drug created at June 23, 2017 20:47 / Updated at February 21, 2021 18:54