Identification
- Brand Names
- Normosol-M, Procalamine 3
- Generic Name
- Magnesium acetate
- DrugBank Accession Number
- DB13996
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Magnesium acetate (DB13996)
- Weight
- Average: 142.393
Monoisotopic: 142.01165037 - Chemical Formula
- C4H6MgO4
- Synonyms
- acetato de magnesio
- acetic acid magnesium salt
- Acetic acid, magnesium salt (2:1)
- Magnesium di(acetate)
- magnesium diacetate
- Mg(II) acetate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Therapies
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
Target Actions Organism USodium/potassium-transporting ATPase subunit alpha-1 Not Available Humans - Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcetazolamide The risk or severity of dehydration can be increased when Acetazolamide is combined with Magnesium acetate. Alfentanil The therapeutic efficacy of Magnesium acetate can be decreased when used in combination with Alfentanil. Amiloride The risk or severity of dehydration can be increased when Amiloride is combined with Magnesium acetate. Amiodarone The therapeutic efficacy of Magnesium acetate can be decreased when used in combination with Amiodarone. Amlodipine The therapeutic efficacy of Magnesium acetate can be decreased when used in combination with Amlodipine. - Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Magnesium cation ionic T6V3LHY838 22537-22-0 JLVVSXFLKOJNIY-UHFFFAOYSA-N - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image AMINOPLASMAL-10% E INFUSION Magnesium acetate (0.56 g/l) + Acetylcysteine (0.5 g/l) + Alanine (13.7 g/l) + Arginine (9.2 g/l) + Asparagine (3.27 g/l) + Aspartic acid (1.3 g/l) + Glutamic acid (4.6 g/l) + Glycine (7.9 g/l) + Histidine (5.2 g/l) + Isoleucine (5.1 g/l) + Leucine (8.9 g/l) + Lysine hydrochloride (5.6 g/l) + Malic acid (1.01 g/l) + Methionine (3.8 g/l) + N-acetyltyrosine (1 g/l) + Ornithine hydrochloride (2.51 g/l) + Phenylalanine (5.1 g/l) + Potassium acetate (2.45 g/l) + Proline (8.9 g/l) + Serine (2.4 g/l) + Sodium acetate (3.95 g/l) + Sodium hydroxide (0.2 g/l) + Sodium phosphate, monobasic (1.4 g/l) + Threonine (4.1 g/l) + Tryptophan (1.8 g/l) + Tyrosine (0.3 g/l) + Valine (4.8 g/l) Injection Intravenous B. BRAUN SINGAPORE PTE LTD 1991-05-13 Not applicable Singapore 
AMINOPLASMAL-5% E INFUSION Magnesium acetate (0.56 g/1000ml) + Acetylcysteine (0.25 g/1000ml) + Alanine (6.85 g/1000ml) + Arginine (4.6 g/1000ml) + Asparagine (1.64 g/1000ml) + Aspartic acid (0.65 g/1000ml) + Glutamic acid (2.3 g/1000ml) + Glycine (3.95 g/1000ml) + Histidine (2.6 g/1000ml) + Isoleucine (2.55 g/1000ml) + Leucine (4.45 g/1000ml) + Lysine hydrochloride (2.8 g/1000ml) + Malic acid (1.01 g/1000ml) + Methionine (1.9 g/1000ml) + N-acetyltyrosine (0.35 g/1000ml) + Ornithine hydrochloride (1.25 g/1000ml) + Phenylalanine (2.55 g/1000ml) + Potassium acetate (2.45 g/1000ml) + Proline (4.45 g/1000ml) + Serine (1.2 g/1000ml) + Sodium acetate (3.95 g/1000ml) + Sodium hydroxide (0.2 g/1000ml) + Sodium phosphate, monobasic (1.4 g/1000ml) + Threonine (2.05 g/1000ml) + Tryptophan (0.9 g/1000ml) + Tyrosine (0.3 g/1000ml) + Valine (2.4 g/1000ml) Injection Intravenous B. BRAUN SINGAPORE PTE LTD 1991-05-13 Not applicable Singapore Aminosyn Magnesium acetate (21 mg/100mL) + Alanine (448 mg/100mL) + Arginine (343 mg/100mL) + Glycine (448 mg/100mL) + Histidine (105 mg/100mL) + Isoleucine (252 mg/100mL) + Leucine (329 mg/100mL) + Lysine acetate (252 mg/100mL) + Methionine (140 mg/100mL) + Phenylalanine (154 mg/100mL) + Phosphoric acid (40 mg/100mL) + Potassium acetate (128 mg/100mL) + Proline (300 mg/100mL) + Serine (147 mg/100mL) + Sodium chloride (234 mg/100mL) + Threonine (182 mg/100mL) + Tryptophan (56 mg/100mL) + Tyrosine (31 mg/100mL) + Valine (280 mg/100mL) Injection, solution Intravenous Hospira, Inc. 2011-03-23 2017-11-01 US 
Aminosyn 3.5% M Magnesium acetate (21 mg / 100 mL) + Alanine (448 mg / 100 mL) + Arginine (343 mg / 100 mL) + Glycine (448 mg / 100 mL) + Histidine (105 mg / 100 mL) + Isoleucine (252 mg / 100 mL) + Leucine (329 mg / 100 mL) + Lysine acetate (252 mg / 100 mL) + Methionine (140 mg / 100 mL) + Phenylalanine (154 mg / 100 mL) + Potassium acetate (128 mg / 100 mL) + Proline (300 mg / 100 mL) + Serine (147 mg / 100 mL) + Sodium chloride (234 mg / 100 mL) + Threonine (182 mg / 100 mL) + Tryptophan (56 mg / 100 mL) + Tyrosine (31 mg / 100 mL) + Valine (280 mg / 100 mL) Liquid Intravenous Abbott 1980-12-31 1999-08-09 Canada 
FreAmine III Magnesium acetate (0.054 g/100mL) + Alanine (0.21 g/100mL) + Arginine (0.29 g/100mL) + Cysteine hydrochloride (0.014 g/100mL) + Glycine (0.42 g/100mL) + Histidine (0.085 g/100mL) + Isoleucine (0.21 g/100mL) + Leucine (0.27 g/100mL) + Lysine acetate (0.22 g/100mL) + Methionine (0.16 g/100mL) + Phenylalanine (0.17 g/100mL) + Phosphoric acid (0.040 g/100mL) + Potassium chloride (0.15 g/100mL) + Proline (0.34 g/100mL) + Serine (0.18 g/100mL) + Sodium acetate trihydrate (0.2 g/100mL) + Sodium chloride (0.12 g/100mL) + Threonine (0.12 g/100mL) + Tryptophan (0.046 g/100mL) + Valine (0.2 g/100mL) Injection, solution Intravenous B. Braun Medical Inc. 1971-09-24 2013-08-01 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Nutrilyte Magnesium acetate (43 mg/1mL) + Calcium acetate (22 mg/1mL) + Sodium gluconate (55 mg/1mL) + Potassium acetate (34.5 mg/1mL) + Potassium chloride (125 mg/1mL) + Sodium acetate trihydrate (135 mg/1mL) Injection, solution, concentrate Intravenous American Regent 1990-09-30 2013-05-08 US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as acetate salts. These are organic compounds containing acetic acid as its acid component.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Carboxylic acids and derivatives
- Sub Class
- Carboxylic acid derivatives
- Direct Parent
- Acetate salts
- Alternative Parents
- Monocarboxylic acids and derivatives / Carboxylic acids / Organic salts / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
- Substituents
- Acetate salt / Aliphatic acyclic compound / Carbonyl group / Carboxylic acid / Hydrocarbon derivative / Monocarboxylic acid or derivatives / Organic oxide / Organic oxygen compound / Organic salt / Organooxygen compound
- Molecular Framework
- Not Available
- External Descriptors
- magnesium salt (CHEBI:62964)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0E95JZY48K
- CAS number
- 142-72-3
- InChI Key
- UEGPKNKPLBYCNK-UHFFFAOYSA-L
- InChI
- InChI=1S/2C2H4O2.Mg/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
- IUPAC Name
- magnesium(2+) diacetate
- SMILES
- [Mg++].CC([O-])=O.CC([O-])=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 8556
- ChEBI
- 62964
- ChEMBL
- CHEMBL1200691
- Wikipedia
- Magnesium_acetate
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection Intravenous 0.5 g/l Injection Intravenous 0.25 g/1000ml Injection, solution Intravenous Solution Intravenous Emulsion Parenteral Emulsion Intravenous Solution Parenteral Injection, solution, concentrate Intravenous Liquid Intravenous Injection Intravenous Injection Intravenous 0.21 g/100ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 98.2 mg/mL ALOGPS logP 0.29 ALOGPS logP -0.22 Chemaxon logS -0.16 ALOGPS pKa (Strongest Acidic) 4.54 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 40.13 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 23.48 m3·mol-1 Chemaxon Polarizability 4.96 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Targets
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- Kind
- Protein
- Organism
- Humans
- Pharmacological action
- Unknown
- General Function
- Steroid hormone binding
- Specific Function
- This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates th...
- Gene Name
- ATP1A1
- Uniprot ID
- P05023
- Uniprot Name
- Sodium/potassium-transporting ATPase subunit alpha-1
- Molecular Weight
- 112895.01 Da
References
- Buchachenko AL, Kuznetsov DA, Berdinskii VL: [New mechanisms of biological effects of electromagnetic fields]. Biofizika. 2006 May-Jun;51(3):545-52. [Article]
- Sirijovski N, Olsson U, Lundqvist J, Al-Karadaghi S, Willows RD, Hansson M: ATPase activity associated with the magnesium chelatase H-subunit of the chlorophyll biosynthetic pathway is an artefact. Biochem J. 2006 Dec 15;400(3):477-84. [Article]
- Balasubramaniyan V, Nalini N: Leptin alters brain adenosine triphosphatase activity in ethanol-mediated neurotoxicity in mice. Singapore Med J. 2006 Oct;47(10):864-8. [Article]
- Nogovitsina OR, Levitina EV: Neurological aspects of the clinical features, pathophysiology, and corrections of impairments in attention deficit hyperactivity disorder. Neurosci Behav Physiol. 2007 Mar;37(3):199-202. [Article]
Drug created at February 23, 2018 21:26 / Updated at June 12, 2020 16:53