This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- p-Aminophenol
- DrugBank Accession Number
- DB14144
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for p-Aminophenol (DB14144)
- Weight
- Average: 109.1259
Monoisotopic: 109.052763851 - Chemical Formula
- C6H7NO
- Synonyms
- 4-Aminobenzenol
- 4-Aminophenol
- 4-Hydroxyaniline
- p-hydroxyaniline
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key p-Aminophenol hydrochloride IWL2N22RFY 51-78-5 RVGOBWDGAVAVPJ-UHFFFAOYSA-N - Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Beautiful Womans Hair Loves Colorful Bubbles Hair Dye 5n Natural Brown Liquid 0.01 mg/1mL Topical Modlina Cosmetics Co., Ltd 2013-08-12 Not applicable US 
SALON CODE Glam Brown Liquid 0.34 g/100mL Topical Daolcosmetic Co.,ltd 2018-09-04 2018-09-10 US SALON CODE Glam Cacao Liquid 0.44 g/100mL Topical Daolcosmetic Co.,ltd 2018-09-04 2018-09-10 US SALON CODE Glam Rose Gold Liquid 0.8 g/100mL Topical Daolcosmetic Co.,ltd 2018-09-04 2018-09-10 US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image SALON CODE Glam Hair Color Glam Brown p-Aminophenol (0.34 g/100mL) + Hydrogen peroxide (5.845 g/100mL) Kit Topical Daolcosmetic Co.,ltd 2018-09-04 Not applicable US SALON CODE Glam Hair Color Glam Cacao p-Aminophenol (0.44 g/100mL) + Hydrogen peroxide (5.845 g/100mL) Kit Topical Daolcosmetic Co.,ltd 2018-09-04 Not applicable US SALON CODE Glam Hair Color Glam Rose Gold p-Aminophenol (0.8 g/100mL) + Hydrogen peroxide (5.845 g/100mL) Kit Topical Daolcosmetic Co.,ltd 2018-09-04 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Beautiful Womans Hair Loves Colorful Bubbles Hair Dye 5n Natural Brown p-Aminophenol (0.01 mg/1mL) Liquid Topical Modlina Cosmetics Co., Ltd 2013-08-12 Not applicable US SALON CODE Glam Brown p-Aminophenol (0.34 g/100mL) Liquid Topical Daolcosmetic Co.,ltd 2018-09-04 2018-09-10 US SALON CODE Glam Cacao p-Aminophenol (0.44 g/100mL) Liquid Topical Daolcosmetic Co.,ltd 2018-09-04 2018-09-10 US SALON CODE Glam Hair Color Glam Brown p-Aminophenol (0.34 g/100mL) + Hydrogen peroxide (5.845 g/100mL) Kit Topical Daolcosmetic Co.,ltd 2018-09-04 Not applicable US SALON CODE Glam Hair Color Glam Cacao p-Aminophenol (0.44 g/100mL) + Hydrogen peroxide (5.845 g/100mL) Kit Topical Daolcosmetic Co.,ltd 2018-09-04 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- R7P8FRP05V
- CAS number
- 123-30-8
- InChI Key
- PLIKAWJENQZMHA-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
- IUPAC Name
- 4-aminophenol
- SMILES
- NC1=CC=C(O)C=C1
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0001169
- KEGG Compound
- C02372
- ChemSpider
- 392
- BindingDB
- 26195
- 1435279
- ChEBI
- 17602
- ChEMBL
- CHEMBL1142
- ZINC
- ZINC000004623758
- PDBe Ligand
- 4NL
- Wikipedia
- 4-Aminophenol
- PDB Entries
- 2orl
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Topical 0.01 mg/1mL Liquid Topical 0.34 g/100mL Liquid Topical 0.44 g/100mL Kit Topical Liquid Topical 0.8 g/100mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 121.0 mg/mL ALOGPS logP 0.47 ALOGPS logP 0.84 Chemaxon logS 0.04 ALOGPS pKa (Strongest Acidic) 10.4 Chemaxon pKa (Strongest Basic) 5.43 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 46.25 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 32.74 m3·mol-1 Chemaxon Polarizability 11.23 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 116.7574819 predictedDarkChem Lite v0.1.0 [M-H]- 116.9490819 predictedDarkChem Lite v0.1.0 [M-H]- 116.7430819 predictedDarkChem Lite v0.1.0 [M-H]- 119.100075 predictedDeepCCS 1.0 (2019) [M-H]- 116.7574819 predictedDarkChem Lite v0.1.0 [M-H]- 116.9490819 predictedDarkChem Lite v0.1.0 [M-H]- 116.7430819 predictedDarkChem Lite v0.1.0 [M-H]- 116.7574819 predictedDarkChem Lite v0.1.0 [M-H]- 116.9490819 predictedDarkChem Lite v0.1.0 [M-H]- 116.7430819 predictedDarkChem Lite v0.1.0 [M-H]- 119.100075 predictedDeepCCS 1.0 (2019) [M-H]- 119.100075 predictedDeepCCS 1.0 (2019) [M+H]+ 117.6470819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6059819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6477819 predictedDarkChem Lite v0.1.0 [M+H]+ 122.36981 predictedDeepCCS 1.0 (2019) [M+H]+ 117.6470819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6059819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6477819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6470819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6059819 predictedDarkChem Lite v0.1.0 [M+H]+ 117.6477819 predictedDarkChem Lite v0.1.0 [M+H]+ 122.36981 predictedDeepCCS 1.0 (2019) [M+H]+ 122.36981 predictedDeepCCS 1.0 (2019) [M+Na]+ 117.0863819 predictedDarkChem Lite v0.1.0 [M+Na]+ 116.8640819 predictedDarkChem Lite v0.1.0 [M+Na]+ 116.8988819 predictedDarkChem Lite v0.1.0 [M+Na]+ 130.97664 predictedDeepCCS 1.0 (2019) [M+Na]+ 117.0863819 predictedDarkChem Lite v0.1.0 [M+Na]+ 116.8640819 predictedDarkChem Lite v0.1.0 [M+Na]+ 116.8988819 predictedDarkChem Lite v0.1.0 [M+Na]+ 117.0863819 predictedDarkChem Lite v0.1.0 [M+Na]+ 116.8640819 predictedDarkChem Lite v0.1.0 [M+Na]+ 116.8988819 predictedDarkChem Lite v0.1.0 [M+Na]+ 130.97664 predictedDeepCCS 1.0 (2019) [M+Na]+ 130.97664 predictedDeepCCS 1.0 (2019)
Drug created at June 27, 2018 20:07 / Updated at June 12, 2020 16:53