Etirinotecan pegol

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Etirinotecan pegol
DrugBank Accession Number
DB14951
Background

Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).

Type
Small Molecule
Groups
Investigational
Synonyms
  • Etirinotecan pegol
External IDs
  • NKTR-102

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AmbroxolThe risk or severity of methemoglobinemia can be increased when Etirinotecan pegol is combined with Ambroxol.
ArticaineThe risk or severity of methemoglobinemia can be increased when Etirinotecan pegol is combined with Articaine.
BenzocaineThe risk or severity of methemoglobinemia can be increased when Etirinotecan pegol is combined with Benzocaine.
Benzyl alcoholThe risk or severity of methemoglobinemia can be increased when Etirinotecan pegol is combined with Benzyl alcohol.
BupivacaineThe risk or severity of methemoglobinemia can be increased when Etirinotecan pegol is combined with Bupivacaine.
Food Interactions
Not Available

Categories

ATC Codes
L01CE03 — Etirinotecan pegol
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
LJ16641SFT
CAS number
848779-32-8
InChI Key
Not Available
InChI
Not Available
IUPAC Name
Not Available
SMILES
Not Available

References

General References
Not Available
Wikipedia
Nektar_Therapeutics

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
Not Available
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at May 20, 2019 14:37 / Updated at February 21, 2021 18:55