Edodekin alfa

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Edodekin alfa
DrugBank Accession Number
DB15631
Background

Edodekin alfa is under investigation in clinical trial NCT01468896 (Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That Is Recurrent, Metastatic, or Cannot Be Removed by Surgery).

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Interleukin-based products
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • Edodekin alfa
  • Human il-12 (recombinant)
  • Interleukin 12 (human)
  • Interleukin-12, human
  • Recombinant Human Interleukin-12
  • Recombinant interleukin-12
External IDs
  • Ro 24-7472
  • RO 24-7472/000
  • RO-24-7472
  • RO-24-7472/000
  • RO-247472000

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AmbroxolThe risk or severity of methemoglobinemia can be increased when Edodekin alfa is combined with Ambroxol.
ArticaineThe risk or severity of methemoglobinemia can be increased when Edodekin alfa is combined with Articaine.
BenzocaineThe risk or severity of methemoglobinemia can be increased when Edodekin alfa is combined with Benzocaine.
Benzyl alcoholThe risk or severity of methemoglobinemia can be increased when Edodekin alfa is combined with Benzyl alcohol.
BupivacaineThe risk or severity of methemoglobinemia can be increased when Edodekin alfa is combined with Bupivacaine.
Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
31Z82G8ME1
CAS number
187348-17-0

References

General References
Not Available
RxNav
1318050

Clinical Trials

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Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at March 07, 2020 20:05 / Updated at January 14, 2023 19:02