NAV

Aluminum subacetate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Aluminum subacetate is a medication used to prevent infection and treat irritation around the rectum.

Generic Name
Aluminum subacetate
DrugBank Accession Number
DB15679
Background

Not Available

Type
Small Molecule
Groups
Approved, Experimental
Structure
Similar Structures
Weight
Average: 162.0769
Monoisotopic: 162.010886775
Chemical Formula
C4H7AlO5
Synonyms
  • Aluminum diaceate
  • Aluminum diacetate
  • Aluminum hydroxyacetate
  • Aluminum subacetate
Poor quality drug data slowing you down?
Unlock 38% more drug discovery time and eliminate decision-making doubts with this one-stop guide to quality drug data.
Download eBook
Poor quality drug data slowing you down?
Download eBook

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination for symptomatic treatment ofHemorrhoidsCombination Product in combination with: Lidocaine (DB00281), Hydrocortisone acetate (DB14539), Zinc oxide (DB09321)•••••••••••••••••••••••
Used in combination for symptomatic treatment ofPost operative painCombination Product in combination with: Zinc oxide (DB09321), Lidocaine (DB00281), Hydrocortisone acetate (DB14539)•••••••••••••••••••••••
Used in combination for symptomatic treatment ofProctitisCombination Product in combination with: Lidocaine (DB00281), Hydrocortisone acetate (DB14539), Zinc oxide (DB09321)•••••••••••••••••••••••
Used in combination for symptomatic treatment ofPruritus aniCombination Product in combination with: Hydrocortisone acetate (DB14539), Zinc oxide (DB09321), Lidocaine (DB00281)•••••••••••••••••••••••
Used in combination for symptomatic treatment ofMild anal fissuresCombination Product in combination with: Zinc oxide (DB09321), Hydrocortisone acetate (DB14539), Lidocaine (DB00281)•••••••••••••••••••••••
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
Not Available

Interactions

Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Buro Sol Antiseptic PowderAluminum subacetate (0.35 %) + Benzethonium chloride (0.023 %)PowderTopicalGlaxosmithkline Inc1985-12-312016-12-06Canada flag
HEMORALGINE 40 GR POMADAluminum subacetate (0.4 g) + Bismuth subgallate (2 g) + Chlorhexidine hydrochloride (0.4 g) + Ephedrine hydrochloride (0.2 g) + Levomenthol (0.8 g) + Tetracaine hydrochloride (0.4 g) + Zinc oxide (3.2 g)OintmentTopicalATABAY İLAÇ FABRİKASI A.Ş.1991-07-19Not applicableTurkey flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
FGL8577C9S
CAS number
142-03-0
InChI Key
HQQUTGFAWJNQIP-UHFFFAOYSA-K
InChI
InChI=1S/2C2H4O2.Al.H2O/c2*1-2(3)4;;/h2*1H3,(H,3,4);;1H2/q;;+3;/p-3
IUPAC Name
(acetyloxy)(hydroxy)alumanyl acetate
SMILES
CC(=O)O[Al](O)OC(C)=O

References

General References
  1. NPRA Product Information: Xyloproct (Aluminum subacetate / Hydrocortisone acetate / Lidocaine / Zinc oxide) rectal ointment/suppository [Link]
ChemSpider
8373332
RxNav
235461
ChEMBL
CHEMBL1532734

Clinical Trials

Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LotionTopical0.059 g
PowderTopical
OintmentTopical
Ointment
SuppositoryRectal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility10.4 mg/mLALOGPS
logP0.21ALOGPS
logP-0.4Chemaxon
logS-1.2ALOGPS
pKa (Strongest Acidic)13.58Chemaxon
pKa (Strongest Basic)-3.4Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area72.83 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity26 m3·mol-1Chemaxon
Polarizability13.6 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at April 28, 2020 19:51 / Updated at May 14, 2021 01:07