Menthone
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Menthone is a medication used to treat stone formation in the gallbladder and liver.
- Generic Name
- Menthone
- DrugBank Accession Number
- DB15920
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 154.253
Monoisotopic: 154.1357652 - Chemical Formula
- C10H18O
- Synonyms
- DL-Menthone
- Menthone G
- External IDs
- 201-941-1
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ROWACHOL CAPSULES Menthone (6 mg) + Borneol (5 mg) + Camphene (5 mg) + Eucalyptol (2 mg) + Levomenthol (32 mg) + Olive oil (33 mg) + alpha-Pinene (17 mg) Capsule Oral DCH AURIGA (MALAYSIA) SDN. BHD. 2020-09-08 Not applicable Malaysia โรวาคอล Menthone (6 mg) + Borneol (5 mg) + Camphene (5 mg) + Eucalyptol (2 mg) + Levomenthol (32 mg) + alpha-Pinene (13.6 mg) + beta-Pinene (3.4 mg) Capsule บริษัท ดีซีเอช ออริกา (ประเทศไทย) จำกัด 1986-09-25 Not applicable Thailand
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 9NH5J4V8FN
- CAS number
- 89-80-5
- InChI Key
- NFLGAXVYCFJBMK-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3
- IUPAC Name
- 5-methyl-2-(propan-2-yl)cyclohexan-1-one
- SMILES
- CC(C)C1CCC(C)CC1=O
References
- General References
- FDA Thailand: Rowachol (Borneol, Camphene, Eucalyptol, Levomenthol, Menthone, Alpha-Pinene, and Beta-Pinene) Oral Capsule [Link]
- External Links
- ChemSpider
- 6720
- ChEBI
- 36742
- ChEMBL
- CHEMBL1719455
- Wikipedia
- Menthone
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral Capsule - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.265 mg/mL ALOGPS logP 2.65 ALOGPS logP 3.05 Chemaxon logS -2.8 ALOGPS pKa (Strongest Basic) -7.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 17.07 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 46.52 m3·mol-1 Chemaxon Polarizability 19.02 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-01qj-9700000000-c156de7fc6eaf5b509ec Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-0900000000-40e722548ee3d085ed47 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0udi-0900000000-af2a05129ae121f567d1 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-000b-9200000000-d1639dfcec62e7ab91c9 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0gbi-3900000000-3648b9f5ae05b0b1f18f Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0536-9200000000-c645d88846ee2e239afa Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 137.1037801 predictedDarkChem Lite v0.1.0 [M-H]- 132.42752 predictedDeepCCS 1.0 (2019) [M+H]+ 138.0210801 predictedDarkChem Lite v0.1.0 [M+H]+ 136.23584 predictedDeepCCS 1.0 (2019) [M+Na]+ 137.2268801 predictedDarkChem Lite v0.1.0 [M+Na]+ 144.9026 predictedDeepCCS 1.0 (2019)
Drug created at November 23, 2020 16:18 / Updated at May 07, 2021 21:08