This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- OM85
- DrugBank Accession Number
- DB16533
- Background
OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
- Type
- Biotech
- Groups
- Investigational
- Synonyms
- Broncho-Vaxom
- OM 85 BV
- OM-85
- OM-85 BV
- External IDs
- OM85
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
OM85 acts on Trif and MyDD8, and is a NLRP3 activator.
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs Browse all" title="About SNP Mediated Effects/ADRs" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug Interactions Learn More" title="About Drug Interactions" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Not Available
- CAS number
- Not Available
References
- General References
- Dang AT, Pasquali C, Ludigs K, Guarda G: OM-85 is an immunomodulator of interferon-beta production and inflammasome activity. Sci Rep. 2017 Mar 6;7:43844. doi: 10.1038/srep43844. [Article]
- External Links
- Not Available
Clinical Trials
- Clinical Trials Learn More" title="About Clinical Trials" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
Phase Status Purpose Conditions Count 4 Completed Prevention Asthma 1 4 Completed Prevention Bronchiectasis With Acute Exacerbation 1 4 Recruiting Treatment Respiratory Tract Infections (RTI) / Wheezing Lower Respiratory Illness 1 4 Unknown Status Prevention Adenoid Hyperplasia / Adenoids Hypertrophy / Preschool Children / Respiratory Tract Infections (RTI) 1 3 Completed Prevention Atopic Dermatitis 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at February 01, 2021 19:18 / Updated at February 13, 2021 10:54