NAV

Hemoximer

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Hemoximer
DrugBank Accession Number
DB17600
Background

Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.1

Type
Biotech
Groups
Investigational
Synonyms
  • Pyridoxalated hemoglobin polyoxyethylene
  • Pyridoxalated-hemoglobin-polyoxyethylene conjugate
External IDs
  • PHP
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
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Not Available

Interactions

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This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
AE1041687F
CAS number
Not Available

References

General References
  1. Malchesky PS, Takahashi T, Iwasaki K, Harasaki H, Nose Y: Conjugated human hemoglobin as a physiological oxygen carrier--pyridoxalated hemoglobin polyoxyethylene conjugate (PHP). Int J Artif Organs. 1990 Jul;13(7):442-50. [Article]
Not Available

Clinical Trials

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PhaseStatusPurposeConditionsCount
3CompletedTreatmentShock / Systemic Inflammatory Response Syndrome (SIRS)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at April 04, 2023 18:10 / Updated at April 07, 2023 13:12