Enzyme Inhibitors

Name

Enzyme Inhibitors

Accession Number

DBCAT000003

Description

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Drugs

Drug	Drug Description
Lepirudin	A protein-based direct thrombin inhibitor used as an anticoagulant in patients with heparin-induced thrombocytopenia.
Bivalirudin	A direct thrombin inhibitor used to treat heparin-induced thrombocytopenia and to prevent thrombosis during percutaneous coronary intervention.
Alpha-1-proteinase inhibitor	A purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
Cyclosporine	A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Pravastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
Fluvoxamine	A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
Ramipril	An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
Masoprocol	Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
Carbidopa	A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
Fluconazole	A triazole antifungal used to treat various fungal infections including candidiasis.
Erythromycin	A macrolide antibiotic used to treat and prevent a variety of bacterial infections.
Caffeine	A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
Sildenafil	A phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
Pyrimethamine	An antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
Remikiren	For the treatment of hypertension and heart failure
Pantoprazole	A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
Moxifloxacin	A fluoroquinolone antibiotic used to treat various bacterial infections.
Nelfinavir	A viral protease inhibitor used in the treatment of HIV infection.
Indinavir	A protease inhibitor used to treat HIV infection.
Lovastatin	An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
Milrinone	A PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure.
Nevirapine	A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
Clotrimazole	A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
Dicoumarol	For decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
Theophylline	A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
Argatroban	A synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
Acarbose	An alpha-glucosidase inhibitor used in adjunctly with diet and exercise for the management of glycemic control in patients with type 2 diabetes mellitus.
Mitomycin	An antimetabolite used as an adjunct to ab externo (outside approach) eye surgeries for the treatment of glaucoma and used as a chemotherapeutic agent for various malignancies.
Valproic acid	An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
Gefitinib	A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
Tolcapone	A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease.
Indomethacin	A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Omeprazole	A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
Nitisinone	A hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods.
Aminoglutethimide	An adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
Mupirocin	An antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes.
Allopurinol	A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
Trimethoprim	An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
Gemcitabine	A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
Chloramphenicol	A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
Nabumetone	An NSAID used to treat osteoarthritis and rheumatoid arthritis.
Ketorolac	An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
Enoxacin	For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria...
Fluoxetine	A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
Celecoxib	An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
Miglitol	An oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
Fosinopril	An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
Entacapone	A selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease.
Zidovudine	A dideoxynucleoside used in the treatment of HIV infection.
Cimetidine	A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
Ritonavir	An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
Trandolapril	A prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction.
Ciprofloxacin	A second generation fluoroquinolone used to treat various susceptible bacterial infections.
Benazepril	An ACE inhibitor prodrug used to treat hypertension.
Pyridostigmine	A cholinesterase inhibitor used for symptomatic treatment of myasthenia gravis and congenital myasthenic syndromes and to reverse neuromuscular blockade by nondepolarizing muscle relaxants.
Acetohydroxamic acid	A synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract.
Zanamivir	A neuraminidase inhibitor used to treat influenza A and B.
Methotrexate	An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Voriconazole	A triazole compound used to treat fungal infections.
Enalapril	A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
Diclofenac	An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Linezolid	An oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
Candoxatril	Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
Imatinib	A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
Triamcinolone	A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Efavirenz	A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
Simvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
Galantamine	A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
Isoflurophate	For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Moexipril	An angiotensin converting enzyme inhibitor prodrug used to treat hypertension.
Daunorubicin	An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
Amprenavir	A protease inhibitor used to treat HIV infection.
Methazolamide	A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
Delavirdine	A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
Paroxetine	A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
Lisinopril	An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
Irinotecan	An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Metyrosine	A tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma.
Clavulanic acid	A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
Nalidixic acid	A quinolone antibiotic used to treat urinary tract infections.
Mefenamic acid	An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
Marimastat	For the treatment of various cancers
Naproxen	An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
Perindopril	An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction.
Pentoxifylline	A methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
Acetazolamide	A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
Tadalafil	A phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
Donepezil	An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
Terbinafine	An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
Tacrolimus	A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
Dorzolamide	A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
Suprofen	An NSAID used to prevent pupil constriction in ocular surgery.
Emtricitabine	A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
Quinapril	An ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
Omapatrilat	For the treatment of hypertension.
Etacrynic acid	A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
Azacitidine	A pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
Demecarium	For the topical treatment of chronic open-angle glaucoma.
Azelastine	A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
Lomefloxacin	A fluoroquinolone used to prevent and treat a wide variety of infections in the body.
Exemestane	An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
Neomycin	An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
Doxorubicin	A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.
Hydroxyurea	An antimetabolite used to treat sickle cell anemia crisis, resistant chronic myeloid leukemia, and Locally advanced squamous cell carcinomas of the head and neck (excluding the lip).
Letrozole	An aromatase inhibitor used to treat breast cancer in postmenopausal women.
Edrophonium	A cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis.
Metyrapone	A steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.
Ketoconazole	A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Topotecan	An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
Gatifloxacin	A fourth generation fluoroquinolone used to treat a wide variety of infections in the body.
Ibuprofen	An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
Norfloxacin	A broad-spectrum fluoroquinolone antibiotic with variable activity against gram-positive and gram-negative bacteria. Typically reserved for the treatment of UTIs due to accumulation in the urine.
Atazanavir	An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
Atorvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Deslanoside	For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
Orlistat	A reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.
Quinacrine	For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
Trilostane	Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Miconazole	An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
Atovaquone	An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
Amiodarone	A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
Dutasteride	An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
Econazole	A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
Levofloxacin	A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
Gemifloxacin	A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
Bupropion	A norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
Trimetrexate	A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
Ofloxacin	An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
Itraconazole	An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
Kanamycin	An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
Orphenadrine	A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
Clindamycin	A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
Brinzolamide	A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Captopril	An ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
Ridogrel	Used as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction.
Clarithromycin	A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
Finasteride	An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
Anastrozole	A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Saquinavir	An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
Gemfibrozil	A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Dasatinib	A tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia or chronic myeloid leukemia.
Lapatinib	An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-positive breast cancer in patients who received prior chemotherapeutic treatments.
Sitagliptin	An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
Decitabine	A chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
Posaconazole	A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Darunavir	A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
Fosamprenavir	An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
Cilazapril	An ACE inhibitor used for the management of hypertension and heart failure.
Spirapril	Spirapril is an ACE inhibitor class drug used to treat hypertension.
Digitoxin	A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
Cilastatin	A renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections.
Lopinavir	An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
Tazobactam	A beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy.
Hydroxychloroquine	An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
Lincomycin	An antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate.
Chymostatin	Not Available
N,N-dimethylarginine	Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which...
Castanospermine	Not Available
Staurosporine	An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Gabaculine	Not Available
Aminooxyacetic acid	A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
3,5-Dinitrocatechol	Not Available
Olomoucine	Not Available
K-252a	Not Available
7-Nitroindazole	Not Available
Ilomastat	Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.
Tolrestat	For the pharmacological control of certain diabetic complications.
Geldanamycin	Not Available
Trehalose-6-Phosphate	Not Available
Phosphoramidon	Not Available
4-Hydroxyphenylglycine	Not Available
LY-294002	Specific inhibitor of phosphatidylinositol 3-kinase.
Fusidic acid	A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
Resveratrol	Being investigated for the treatment of Herpes labialis infections (cold sores).
Kifunensine	Not Available
Pyrazole	Not Available
N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline	Not Available
Calyculin A	Not Available
Dazoxiben	Not Available
Benzamidine	A drug used to treat painful and inflammatory conditions of the oral cavity, such as infections and gingivitis.
Imidazole	Not Available
Enalkiren	Not Available
Ubenimex	An adjuvant therapy used for acute and chronic myelonous leukemia, lung cancer and nasopharyngeal cancer. It is also used to treat hypercholesterolaemia.
Sparfosic acid	Sparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
Eniluracil	For the treatment of cancer in combination with 5-fluorouracil.
Palmitic Acid	A fatty used as a food additive and emollient or surfactant in cosmetics.
Batimastat	Not Available
S-Hexylglutathione	Not Available
Nitroarginine	An inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in...
Oxfenicine	Oxfenicine in an inhibitor of myocardial metabolism of nonesterified fatty acids (NEFA).
Maleic acid	Not Available
D-4-hydroxyphenylglycine	Not Available
Glyphosate	Not Available
5-iodotubercidin	Not Available
Metoprine	Not Available
Vildagliptin	A once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
Ximelagatran	For the treatment of acute deep vein thrombosis.
Stannsoporfin	Investigated for use/treatment in liver disease, metabolic disease, and pediatric indications.
Belinostat	A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
Prinomastat	Investigated for use/treatment in brain cancer, lung cancer, and prostate cancer.
Elafin	Investigated for use/treatment in inflammatory disorders (unspecified).
Oxypurinol	Intended for the treatment of congestive heart failure and hyperuricemia.
Ecabet	For the treatment of reflux oesophagitis and peptic ulcer disease.
Dexlansoprazole	A proton pump inhibitor used to treat erosive esophagitis, heartburn, and gastroesophageal reflux disease (GERD).
Abiraterone	An antiandrogen used in the treatment of metastatic castration-resistant prostate cancer and metastatic high-risk castration-sensitive prostate cancer.
Alogliptin	A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
Rivaroxaban	A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
Eflornithine	An ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients
Simeprevir	A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
Saxagliptin	An DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
Idraparinux	Investigated for use/treatment in thrombosis, venous thromboembolism, strokes, heart disease, and atrial fibrillation.
Tezacitabine	Investigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer.
Apixaban	An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
Axitinib	An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
N-chlorotaurine	Investigated for use/treatment in eye disorders/infections.
Otamixaban	Investigated for use/treatment in thrombosis.
Aprotinin	A serine protease inhibitor used to reduce the risk for perioperative blood loss and the need for blood transfusion in high-risk patients during cardiopulmonary bypass for coronary artery bypass graft surgery.
Dabigatran etexilate	An anticoagulant used for the prevention of venous thromboembolic events or stroke in patients with recent elective hip or knee replacement surgery and atrial fibrillation.
beta-Naphthoflavone	β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Bafilomycin A1	The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus. These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins...
Besifloxacin	A fluoroquinolone antibiotic agent used for the treatment of bacterial conjunctivitis.
Raltegravir	An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
Z-Val-Ala-Asp fluoromethyl ketone	Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the...
5-(2-methylpiperazine-1-sulfonyl)isoquinoline	Not Available
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline	Potent reversible inhibitor of phenylethanolamine N-methyltransferase.
Thiorphan	A potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
Temocapril	Temocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
Pitavastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Rilpivirine	A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
Crizotinib	A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
Linagliptin	A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
Formestane	For the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Dabrafenib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Dolutegravir	An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
Eliglustat	A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers.
Idelalisib	An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
Avibactam	A non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia.
Ceritinib	An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.
Cobicistat	A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
Palbociclib	An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Edoxaban	A novel oral anticoagulant used for reducing the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF).
Lenvatinib	A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
Nintedanib	A triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
Methylene blue	An oxidation-reduction agent used for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Osimertinib	A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
Mersalyl	Elevated blood pressure, edema [L1577, L1585].
Enalaprilat	An antihypertensive agent used for the management of hypertension when oral therapy is not practical.
Deslorelin	Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones.
Antithrombin III human	An alpha-2-glycoprotein used to prevent thromboembolisms in patients with hereditary antithrombin III deficiency.
Candoxatrilat	A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP,...
Opicapone	A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor.
Curcumin	No approved therapeutic indications.
Racecadotril	An anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea.
Talazoparib	A poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer and HRR gene-mutated metastatic castration-resistant prostate cancer.
Imidapril	An ACE inhibitor used in the treatment of essential hypertension.
Tilarginine	Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.
Ruboxistaurin	Ruboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus.
Lanopepden	Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial.
6-O-benzylguanine	6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
Safingol	Safingol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Delanzomib	Delanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin.
Letaxaban	Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
Ulinastatin	Ulinastatin has been investigated for the prevention of Cardiovascular Disease and Adverse Reaction to Drug.
S-3304	S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non...
Atamestane	Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent.
Darexaban	Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
Cantharidin	A natured product indicated to treat molluscum contagiosum
Relebactam	A beta-lactamase inhibitor used to prevent hydrolysis of beta-lactam antibiotics, leading to increased effectiveness.
Nitroaspirin	Nitroaspirin has been investigated for the treatment of Intermittent Claudication.
Nafamostat	Used as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement...
Salirasib	Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
N-omega-nitro-L-arginine methyl ester	L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
Benserazide	A medication used to treat Parkinson's disease, parkinsonism, and restless leg syndrome.
Gabexate	A protease inhibitor indicated in the treatment of acute pancreatitis.
Sivelestat	Sivelestat has been used in trials studying the treatment of Acute Lung Injury and Respiratory Distress Syndrome, Adult.
Buthionine sulfoximine	Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Nolatrexed	Nolatrexed is under investigation in clinical trial NCT00012324 (Nolatrexed Dihydrochloride Compared With Doxorubicin in Treating Patients With Recurrent or Unresectable Liver Cancer).
Didox	Didox has been used in trials studying the supportive care of Gastric Cancer.
Zofenopril	An ACE inhibitor indicated in the treatment of hypertension.
Rhein	No approved indication.
Proscillaridin	Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,...
Delapril	An ACE inhibitor indicated in the treatment of essential hypertension.
Flurithromycin	Not Annotated
Melagatran	Not Annotated
Camostat	A serine protease indicated in Japan to treat chronic pancreatitis.
Calcium levulinate	This new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and...
ABT-341	ABT-341 is a potent and selective DPP-4 inhibitor with a structure very similar to sitagliptin (in 2D; the 3D structure is significantly different).
Concanamycin A	Concanamycin A is an H+-ATPase (vacuolar) inhibitor.
Benazeprilat	Not Annotated
Tenofovir	A nucleotide analog indicated in the treatment of HIV infections.
Fosinoprilat	Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Ramiprilat	The active metabolite of the prodrug Ramipril.
Perindoprilat	The active metabolite of the prodrug Perindopril.
Quinaprilat	The active metabolite of the prodrug quinapril.
Lithium carbonate	A medication used to treat manic episodes of bipolar disorder.
Magnesium levulinate	A supplement to treat magnesium deficiency.
Acifluorfen	Acifluorfen is a protoporphyrinogen oxidase inhibitor.
acetylleucyl-leucyl-norleucinal	Not Available
Cholesterol sulfate	Component of human seminal plasma & spermatozoa.
Zenarestat	Investigated for use/treatment in neuropathy (diabetic).
Oseltamivir acid	Not Available
Isoliquiritigenin	Isoliquiritigenin is a precursor to several flavonones in many plants.
Brequinar	Not Available
Meglutol	An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as...
Pimagedine	Investigated for use/treatment in diabetic kidney disease.
Dabigatran	Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate.
Methoxy arachidonyl fluorophosphonate	Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid...
Salvianolic acid A	Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
Antipain	Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells...
Epalrestat	Epalrestat is under investigation in clinical trial NCT03244358 (Evaluation of Epalrestat in Metastatic Triple-negative Breast Cancer).
Famciclovir	A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
Caspofungin	An echinocandin used to treat a variety of fungal infections.
Fondaparinux	An anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction.
Fomepizole	An inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
Sunitinib	A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Topiroxostat	Indicated for the treatment of gout and hyperurcemia in Japan.
D-Eritadenine	Not Available
Myxothiazol	Not Available
Rupintrivir	Investigated for use/treatment in viral infection.
Ranirestat	Investigated for use/treatment in neuropathy (diabetic).
Arylacenamide	Investigated for use/treatment in cancer/tumors (unspecified), immunosuppressive, and prostate cancer.
Human C1-esterase inhibitor	A C1 inhibitor used to prevent angioedema attacks associated with hereditary angioedema.
Lonafarnib	A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies.
Desirudin	Indicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery.
Asunaprevir	An NS3 protease inhibitor used to treat hepatitis C genotype 1b.
Adavosertib	MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
Pevonedistat	Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
PF-04991532	PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.
Tosedostat	Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the...
Bempedoic acid	A drug used in conjunction with lifestyle modification and/or other agents for the treatment of refractory hypercholesterolemia.
Entrectinib	Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
Vaborbactam	A beta lactamase inhibitor used to treat complicated urinary tract infections.
Obatoclax	Obatoclax has been used in trials studying the treatment of AML, Leukemia, Myelofibrosis, Hodgkin's Lymphoma, and Mantle-Cell Lymphoma, among others.
Betrixaban	A Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients.
Zamicastat	Zamicastat has been used in trials studying the treatment of Hypertension and Chronic Heart Failure.
Galeterone	Galeterone has been used in trials studying the treatment of Prostate Cancer.
Anagliptin	Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
WNT-974	WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.
Ivosidenib	An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults with a susceptible IDH1 mutation.
CPI-1205	Potent and selective histone methyltransferase EZH2 inhibitor.
Selitrectinib	Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers).
Imetelstat	Imetelstat is under investigation in clinical trial NCT01916187 (Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma).
Serabelisib	Serabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics of TAK-117 (MLN1117)...
Linrodostat	Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants).
Zanubrutinib	A kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
Upadacitinib	An oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, and severe atopic dermatitis, including in patients who did not respond well to other therapies.
Paxalisib	GDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
Avidin	Avidin is under investigation in clinical trial NCT00345618 (Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach).
CB-1158	CB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).
p-Hydroxymercuribenzoic acid	Not Available
2-deoxy-2,3-dehydro-N-acetylneuraminic acid	Not Available
Thiocitrulline	Not Available
N(G)-Iminoethylornithine	Not Available
R-82913	Not Available
H-89	Not Available
Zopolrestat	Not Available
CGS-27023	Not Available
Bisindolylmaleimide VIII	Not Available
CP-320626	Not Available
GW-813893	Not Available
Bisindolylmaleimide I	Not Available
5-Benzylacyclouridine	Not Available
Dorsomorphin	Not Available
Adenosine 5'-methylenediphosphate	Not Available
Methyldopa	A centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises.
Vigabatrin	An irreversible GABA transaminase inhibitor used as an adjunct therapy to treat refractory complex partial seizures in patients ≥2 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years.
Zinc protoporphyrin	Not Available
Baicalein	Baicalein is under investigation in clinical trial NCT03830684 (A Randomized, Double-blind, Placebo-controlled, Multicenter and Phase ⅡA Clinical Trial for the Effectiveness and Safety of Baicalein Tablets in the Treatment of...
Firsocostat	Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)).
Racemetyrosine	Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Tin protoporphyrin IX	Not Available
Telaprevir	An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections.
Boceprevir	A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
Faldaprevir	Faldaprevir has been investigated for the treatment of Chronic Hepatitis C.
Conestat alfa	A recombinant C1INH used for the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults.
Tipranavir	A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
Epicaptopril	Not Available
Carbomer	Not Annotated
Nirmatrelvir	An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.
N-Ethylmaleimide	A sulfhydryl reagent that is widely used in experimental biochemical studies. [PubChem]
Tirbanibulin	A tyrosine kinase and tubulin inhibitor used to treat actinic keratosis on the face or scalp.
AR-9281	Investigated for use/treatment in hypertension.
RG-4733	Ro4929097 has been used in trials studying the treatment of Sarcoma, LYMPHOMA, Neoplasms, Wilm's Tumor, and OSTEOSARCOMA, among others.
Sorivudine	Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
1,10-Phenanthroline	Not Available
Cidofovir	An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
Miglustat	A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
Acetyldigitoxin	Used for fast digitalization in congestive heart failure.
Pemetrexed	A folate analog used to treat mesothelioma and non-small cell lung cancer.
Quinidine	A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Mycophenolic acid	An immunosuppressant used to prevent organ transplant rejections.
Novobiocin	For the treatment of infections due to staphylococci and other susceptible organisms
Ouabain	For the treatment of atrial fibrillation and flutter and heart failure
Leflunomide	A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
Desipramine	A tricyclic antidepressant used in the treatment of depression.
Alrestatin	Not Available
Daidzin	Not Available
S-Ethylisothiourea	S-Ethylisothiourea is a nitric oxide synthase inhibitor.
5'-S-methyl-5'-thioadenosine	Not Available
Phosphonoacetic Acid	A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]
Duvoglustat	An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Phencyclidine	A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like...
Radicicol	Not Available
1-deoxymannojirimycin	An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem]
Dipicolinic acid	Not Available
Monastrol	Not Available
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide	Not Available
Allosamidin	Allosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
2,5-di-tert-butylhydroquinone	Not Available
Lawsone	Not Available
Permethrin	An insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
Amonafide	Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.
Tetrathiomolybdate	Investigated for use/treatment in liver disease and pulmonary fibrosis.
Cetilistat	Investigated for use/treatment in obesity.
Peramivir	An intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.
Iobenguane	A radiopharmaceutical agent used for the diagnosis of primary and metastatic pheochromocytoma or neuroblastoma.
t-Butylhydroquinone	Not Available
Dichlororibofuranosylbenzimidazole	Not Available
Y-27632	Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
Rebamipide	A gastroprotective agent used in combination with other similar therapies (e.g. proton pump inhibitors) to treat gastritis and protect the gastric mucosa.
Peficitinib	Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others.
Saracatinib	Saracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.
Pritelivir	Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
Ozagrel	Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.
Lobucavir	Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Mizoribine	Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
Apocynin	Acetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease.
Phenethyl Isothiocyanate	Phenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
Nikkomycin Z	Nikkomycin Z has been used in trials studying the treatment and basic science of Coccidioidomycosis.
Mitoguazone	Mitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.
Hypericin	Hypericin is under investigation for the treatment of Cutaneous T-cell Lymphoma.
Liarozole	Liarozole has been used in trials studying the treatment of Ichthyosis, Lamellar.
Linsidomine	Not Annotated
Metildigoxin	A digitalis glycoside indicated in the treatment of acute and chronic heart failure.
Acetyldigoxin	Not Annotated
Brodimoprim	Not Annotated
Baloxavir marboxil	A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
Basifungin	Basifungin, also known as aureuobacidin A, is a phosphorylceramide synthase inhibitor , .
Ribavirin monophosphate	Not Annotated
Fulacimstat	Fulacimstat is under investigation in clinical trial NCT02452515 (A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction).
JNJ-42165279	Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).
Perillyl alcohol	Perillyl alcohol is under investigation in clinical trial NCT02704858 (Safety and Efficacy Study in Recurrent Grade IV Glioma).
Petesicatib	Petesicatib is under investigation in clinical trial NCT02295332 (A Study of RG7625 in Healthy Volunteers).
Cilazaprilat	Not Annotated
TMC-310911	TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections....
Islatravir	Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
Baloxavir	Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
Aclimostat	Aclimostat is under investigation in clinical trial NCT03254368 (Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes).
Berotralstat	An inhibitor of plasma kallikrein used for prophylaxis of angioedema attacks in patients with hereditary angioedema.
Ticlopidine	A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
Idoxuridine	A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
Dapsone	A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
Raltitrexed	A folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
Ethoxzolamide	For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
Capreomycin	An aminoglycoside antibiotic used as an adjunct drug in tuberculosis.
Pimecrolimus	A topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
Grepafloxacin	A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
Dexrazoxane	A cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.
Tacrine	An anticholinesterase drug used for the management of Alzheimer's disease symptoms.
Valrubicin	An anthracycline used intravesically in the treatment of BCG-resistant bladder carcinoma.
Sorafenib	A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma.
Cerivastatin	A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events.
Teniposide	A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
Epirubicin	An anthracycline topoisomerase II inhibitor used as an adjuvant to treating axillary node metastases in patients who have undergone surgical resection of primary breast cancer.
Tenoxicam	An anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
Rimantadine	An RNA synthesis inhibitor used to prevent influenza A infection.
Pefloxacin	An antibiotic used to treat a variety of bacterial infections.
Tolmetin	An NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
Foscarnet	An antiviral used to treat CMV, HIV, and HSV infections.
Erlotinib	An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Rofecoxib	A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
Pentostatin	An adenosine deaminase inhibitor used to treat hairy cell leukemia.
Piroxicam	An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
Tigecycline	A glycylcycline antibiotic used to treat a number of susceptible bacterial infections.
Fenoprofen	An anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
Valdecoxib	A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
Sulindac	An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
Furazolidone	A drug for the treatment of infectious diarrhea.
Stavudine	A dideoxynucleoside used in the treatment of HIV infection.
Dyphylline	A theophylline derivative used to treat asthma, bronchospasm, and COPD.
Trovafloxacin	An antibiotic used to treat gonorrhea and chlamydia.
Lamivudine	A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
Diethylcarbamazine	An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.
Flurbiprofen	An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Adefovir dipivoxil	A nucleotide analog used to treat chronic hepatitis B.
Esomeprazole	A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
Zileuton	A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
Etodolac	An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Tranylcypromine	A monoamine oxidase inhibitor used to treat major depressive disorder.
Tetracycline	An antibiotic used to treat a wide variety of susceptible infections.
Malathion	A parasympathomimetic organophosphate used to treat head lice.
Etoposide	A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Phenelzine	A monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
Gentamicin	An aminoglycoside used to treat a wide variety of aerobic infections in the body.
Disulfiram	A carbamate derivative used to treat alcohol addiction.
Cinoxacin	For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and...
Diflunisal	An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
Vardenafil	A phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
Didanosine	A reverse transcriptase inhibitor used to treat HIV.
Levosimendan	A calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure.
Salicylic acid	An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Meclofenamic acid	An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
Zalcitabine	A dideoxynucleoside used to treat HIV.
Netilmicin	An aminoglycoside used to treat a wide variety of infections in the body.
Dactinomycin	An actinomycin used to treat a wide variety of cancers.
Dipyridamole	A phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
Physostigmine	A cholinesterase inhibitor used to treat glaucoma and anticholinergic toxicity.
Rivastigmine	A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's.
Oxaprozin	An NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
Tioconazole	An imidazole antifungal used to treat vulvovaginal candidiasis.
Ketoprofen	An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
Mercaptopurine	An antineoplastic agent used to treat acute lymphocytic leukemia.
Selegiline	A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
Rifampicin	An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
Abacavir	An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV.
Echothiophate	An acetylcholinesterase inhibitor used in ophthalmic preparations to increase the drainage of intraocular fluid; most commonly used for the treatment of glaucoma.
Rosuvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Papaverine	An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
Ambenonium	A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis.
Rabeprazole	A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
Diclofenamide	A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
Cilostazol	An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
Moclobemide	A monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
Idarubicin	An anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
Mitoxantrone	A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
Sparfloxacin	A fluoroquinolone antibiotic used to treat bacterial respiratory infections and sinusitis.
Aminophylline	A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
Isocarboxazid	A monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
Telbivudine	A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
Lumiracoxib	For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
Rasagiline	An irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
Mibefradil	For the treatment of angina and high blood pressure.
Magnesium salicylate	An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
Neostigmine	A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone.
Temafloxacin	For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
Amrinone	A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
Pargyline	For the treatment of moderate to severe hypertension.
Etoricoxib	A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
Genistein	Currently Genistein is being studied in clinical trials as a treatment for prostate cancer.
(Rp)-cAMPS	Not Available
Piclamilast	Piclamilast (RP-73,401), is a selective PDE4 inhibitor comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as...
7-Hydroxystaurosporine	Not Available
Rolipram	A phosphodiesterase inhibitor with antidepressant properties.
Vorinostat	A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	Not Available
Zardaverine	Not Available
Arsanilic acid	An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem]
3-Methoxybenzamide	Not Available
Alvocidib	Investigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	Not Available
Picric acid	Used as antiseptic, astringent, and stimulant for epitheliazation.
Piritrexim	Piritrexim has been used in trials studying the treatment of Bladder Cancer, Urethral Cancer, and Transitional Cell Cancer of the Renal Pelvis and Ureter.
Cilomilast	Investigated for use/treatment in chronic obstructive pulmonary disease (COPD).
Clorgiline	An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Sparsomycin	An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Trichostatin A	Not Available
3,4-Dichloroisocoumarin	Not Available
2,4-Dinitrophenol	A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman,...
Niflumic acid	A cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
Fleroxacin	Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.
Camptothecin	Investigated for the treatment of cancer.
Licofelone	For the management of osteoarthritis.
Nimesulide	A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea.
Benoxaprofen	The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...
Iproniazid	For the treatment of depression (originally intended to treat tuberculosis).
Nialamide	Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Cediranib	For the treatment of liver cancer, advanced non-small cell lung cancer (NSCLC), advanced colorectal cancer (CRC) and other solid tumors.
Huperzine A	Investigated for use/treatment in alzheimer's disease.
Omacetaxine mepesuccinate	A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors.
Halofuginone	For the treatment of scleroderma, cancer, and restenosis.
Voglibose	An alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes.
Vatalanib	Used in combination with first- and second-line chemotherapy for the treatment of metastatic colorectal cancer and non-small cell lung cancer (NSCLC).
Enoximone	A selective phosphodiesterase inhibitor indicated in the short term treatment of congestive heart failure.
Phenserine	For the treatment of Alzheimer's disease (AD).
Ranpirnase	For the treatment of various forms of cancer.
E-2012	Investigated for use/treatment in alzheimer's disease.
Ibudilast	For the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
Tarenflurbil	Investigated for use/treatment in alzheimer's disease and prostate cancer.
SN-38	Investigated for use/treatment in colorectal cancer.
Pelitinib	Investigated for use/treatment in colorectal cancer and lung cancer.
Motesanib	Investigated for use/treatment in solid tumors.
Apremilast	A non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis.
Varespladib methyl	Investigated for use/treatment in atherosclerosis and coronary artery disease.
AV-412	Investigated for use/treatment in cancer/tumors (unspecified).
Rubitecan	Investigated for use/treatment in pancreatic cancer, leukemia (unspecified), melanoma, ovarian cancer, and cancer/tumors (unspecified).
Garenoxacin	Investigated for use/treatment in bacterial infection.
Romidepsin	A histone deacetylase (HDAC) inhibitor used to treat cutaneous T-cell lymphoma.
Pixantrone	An antineoplastic agent use to treat patients with relapsed or refractory aggressive Non-Hodgkin B-cell Lymphomas (NHL).
Seliciclib	Investigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).
Elvucitabine	Investigated for use/treatment in hepatitis (viral, B) and HIV infection.
Exisulind	Investigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications.
Udenafil	A PDE5 inhibitor used to treat erectile dysfunction.
Temsirolimus	A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
Darapladib	Investigated for use/treatment in atherosclerosis.
Iclaprim	Investigated for use/treatment in bacterial infection, skin infections/disorders, obesity, liver disease, kidney disease, and pneumonia.
Indisulam	Investigated for use/treatment in lung cancer.
Etravirine	A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
Semaxanib	Investigated for use/treatment in colorectal cancer and lung cancer.
MLN576	Investigated for use/treatment in solid tumors.
Midostaurin	An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
Panobinostat	A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
Mevastatin	Not used therapeutically due to its many side effects.
Mafenide	An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds.
Plicamycin	For the treatment of testicular cancer, as well as hypercalcemia and hypercalciuria associated with a variety of advanced forms of cancer.
Viomycin	Viomycin is an essential component in the drug cocktail currently used to fight infections of Mycobacterium tuberculosis.
Veliparib	Not Available
4-(2-Aminoethyl)Benzenesulfonyl Fluoride	Not Available
Brefeldin A	A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Anisomycin	Anisomycin (sometimes known as flagecidin), is an antibiotic retrieved from the bacteria Streptomyces griseolus. This drug acts to inhibit bacterial protein and DNA synthesis.
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide	Not Available
Emodin	Emodin has been investigated for the treatment of Polycystic Kidney.
Harmine	Not Available
3-isobutyl-1-methyl-7H-xanthine	Not Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide	Not Available
Wortmannin	Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
Fasudil	Fasudil has been investigated in Carotid Stenosis.
Emivirine	Emivirine has been used in trials studying the treatment of HIV Infections.
Puromycin	Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting...
Parecoxib	A selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
Capravirine	Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
Aminopterin	Prior to its withdrawal, aminopterin was initially used in the treatment of childhood leukemia; specifically to induce remissions. Later, aminopterin was used off-label in the United States to treat psoriasis,...
Vemurafenib	A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
Tofacitinib	A Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis.
Ponatinib	A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
Trametinib	A kinase inhibitor used alone or in combination with dabrafenib to treat patients with cancers with specific BRAF mutations, such as melanoma and non-small cell lung cancer.
Afatinib	An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.
Indoprofen	A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
Flumequine	Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Fenbufen	Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
Finafloxacin	Finafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
Chlortetracycline	The first tetracycline antibiotic most commonly used for veterinary purposes.
Elvitegravir	An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
Pirlindole	For the treatment of major depression. It is being studied in the treatment of fibromyalgia pain syndrome. One study determined that the effect of pirlindole on sensorimotor performance while driving...
Toloxatone	For the treatment of major depressive disorder.
Doxofylline	A methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms.
Trapidil	Used in the treatment of chronic stable angina .
Alirocumab	A PCSK9 inhibitor used as an adjunct to manage heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-cholesterol (LDL-C).
Evolocumab	A PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor antibody used as an adjunct to LDL cholesterol reducing therapies, aiding in the prevention of cardiovascular events and cardiovascular revascularization procedures.
Sulbactam	An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
Alatrofloxacin	A fluoroquinolone antibiotic used to treat a variety of bacterial infections.
Coumaphos	This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
Dichlorvos	Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...
Fenthion	Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...
Monensin	Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
Pimobendan	Not Annotated
Rotenone	Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
Metrifonate	Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Virginiamycin	Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent...
Isatoic anhydride	Not Available
Aclarubicin	Not Annotated
Tucatinib	A kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer.
Ilorasertib	Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Ipatasertib	Ipatasertib has been used in trials studying the treatment of Cancer, Neoplasms, Solid Cancers, Breast Cancer, and Gastric Cancer, among others.
Cabotegravir	An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection.
Momelotinib	A Janus Kinase inhibitor used to treat intermediate or high-risk myelofibrosis.
Spebrutinib	Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
Pazufloxacin	Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
Mirodenafil	Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
Niraparib	A poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
GSK-2636771	GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.
Mocetinostat	Mocetinostat has been used in trials studying the treatment of Lymphoma, Urothelial Carcinoma, Relapsed and Refractory, Myelodysplastic Syndrome, and Metastatic Leiomyosarcoma, among others.
Entinostat	Entinostat is under investigation for the treatment and other of Volunteers, Breast Cancer, Human Volunteers, and Normal Volunteers. Entinostat has been investigated for the treatment of Non-Small Lung Cancer, Epigenetic...
Bafetinib	Bafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Acridine Carboxamide	Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.
Prulifloxacin	A broad-spectrum fluoroquinolone antibiotic used to treat a variety of susceptible bacterial infections.
Avagacestat	Avagacestat has been investigated for the basic science and treatment of Alzheimer Disease.
Gedatolisib	Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer, Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others.
Flumatinib	Flumatinib has been used in trials studying the treatment of Myelogenous Leukemia, Chronic.
Lapachone	Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.
Tesevatinib	Tesevatinib has been used in trials studying the treatment of Cancer, Stomach Cancer, Brain Metastases, Esophageal Cancer, and Leptomeningeal Metastases, among others. Tesevatinib is a potent inhibitor of multiple RTKs...
Nirogacestat	A gamma-secretase inhibitor used to treat desmoid tumors
Prexasertib	Prexasertib has been used in trials studying the treatment and basic science of mCRPC, Leukemia, Neoplasm, breast cancer, and Ovarian Cancer, among others.
Naquotinib	Naquotinib has been used in trials studying the treatment of Solid Tumors, Non-small Cell Lung Cancer, Non-Small-Cell Lung Cancer (NSCLC), Epidermal Growth Factor Receptor Mutations, and Epidermal Growth Factor Receptor...
Letermovir	An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease.
Orantinib	Orantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others.
Vesnarinone	Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
Vinpocetine	A synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
GSK-256066	Gsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others.
Rigosertib	Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.
Exatecan	Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Begacestat	Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.
Atevirdine	Atevirdine has been used in trials studying the treatment of HIV Infections.
Seviteronel	Seviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Simendan	Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
Tacedinaline	Tacedinaline has been used in trials studying the treatment of Lung Cancer, Multiple Myeloma, and Pancreatic Cancer.
Rucaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Ricolinostat	Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
R-306465	R306465 has been used in trials studying the treatment of Neoplasms.
Nadifloxacin	A topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections.
Tempol	Tempol has been used in trials studying the treatment of Anal Cancer.
Belotecan	Belotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
Semagacestat	Semagacestat has been used in trials studying the treatment of Alzheimer Disease.
Dexelvucitabine	Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
Acotiamide	Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
Oltipraz	Oltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
Indobufen	A reversible platelet aggregation inhibitor used to prevent coronary and peripheral artery occlusion.
Abexinostat	Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase...
Rimacalib	Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
Piperine	Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
Sisomicin	Sisomicin has been used in trials studying the treatment of Pyoderma.
Ebselen	Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus.
PF-477736	PF-00477736 has been used in trials studying the treatment of Neoplasms.
NB-001	NB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
Bindarit	Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy.
Atreleuton	Atreleuton has been used in trials studying the treatment of Atherosclerosis and Coronary Artery Disease.
Lometrexol	Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
MK-0752	Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer).
Rebastinib	Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.
MK-0873	MK-0873 has been used in trials studying the treatment of Rheumatoid Arthritis.
Methanesulfonyl Fluoride	Methanesulfonyl Fluoride has been used in trials studying the treatment of Safety.
Delpazolid	Delpazolid (LCB01-0371) is under investigation in clinical trial NCT01554995 (A Clinical Study, Randomized, Double-blind, Placebo-controlled, Single Dose Study).
Talarozole	Talarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
AZD-0424	AZD0424 has been used in trials studying the treatment of Advanced Solid Tumours.
X-396	X-396 has been used in trials studying the treatment of Advanced Solid Tumors and Non-small Cell Lung Cancer.
BMS-986115	BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.
Daidzein	Not Annotated
Sitafloxacin	A fluoroquinolone antibiotic indicated in the treatment of susceptible bacterial infections.
Emetine	Not Annotated
Tenidap	Not Annotated
Paraoxon	Not Annotated
Oxolinic acid	Not Annotated
Proquazone	Not Annotated
Distigmine	A cholinesterase inhibitor indicated in the treatment of neurogenic bladder dysfunction or myasthenia gravis.
Dexrabeprazole	A proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers.
Vorozole	Not Annotated
Rufloxacin	A fluoroquinolone antibiotic indicated in the treatment of susceptible respiratory infections and uncomplicated cystitis.
Reposal	Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.
Adefovir	Not Annotated
Harmaline	Not Annotated
Brofaromine	Not Annotated
Iniparib	Not Annotated
Coumermycin A1	Not Annotated
Clinafloxacin	Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of...
Furafylline	Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
SC-236	SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .
NS-398	NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.
Elapegademase	A recombinant adenosine deaminase used to treat adenosine deaminase severe combined immune deficiency.
Cycloguanil	Cycloguanil is the active metabolite of proguanil.
Rivoceranib	Rivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).
Pamiparib	Pamiparib is under investigation in clinical trial NCT03933761 (Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly...
Ensartinib	Ensartinib is under investigation in clinical trial NCT03420508 (Treating Patients With Melanoma and ALK Alterations With Ensartinib).
Rovafovir etalafenamide	Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen).
Selonsertib	Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
Etirinotecan pegol	Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).
Abrocitinib	A kinase inhibitor used to treat moderate-to-severe atopic dermatitis in adults.
PF-06700841	PF-06700841 is under investigation in clinical trial NCT03236493 (Safety and Pharmacokinetic Study of PF-06700841 in Japanese Healthy Volunteers).
Agerafenib	Agerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
Onvansertib	Onvansertib is under investigation in clinical trial NCT03303339 (Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML).).
Voruciclib	Voruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
KRN-5500	KRN-5500 is under investigation in clinical trial NCT00002923 (KRN5500 in Treating Patients With Metastatic Solid Tumors).
Vorolanib	Vorolanib is under investigation in clinical trial NCT03904719 (CM082 and JS001 in Patients With Advanced Small-cell Lung Cancer (SCLC)).
Ravoxertinib	Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors).
Tenalisib	Tenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).
Vactosertib	Vactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).
Posiphen	Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Abivertinib	Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in...
Branebrutinib	Branebrutinib is under investigation in clinical trial NCT02705989 (Safety, Tolerability and Relative Bioavailability Study of BMS-986195 in Healthy Subjects).
Fialuridine	Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).
Acumapimod	Acumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
Citarinostat	Citarinostat is under investigation in clinical trial NCT02886065 (A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM).
Echinomycin	Echinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from Streptomyces echinatus that binds to DNA and inhibits RNA synthesis.
Ursolic acid	Not Annotated
Carbaryl	A medication used in shampoo to remove lice.
Garlic oil	Not Annotated
FF-10101-01	FF-10101-01 is under investigation in clinical trial NCT03194685 (Study of FF-10101-01 in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Acrizanib	Acrizanib is under investigation in clinical trial NCT02355028 (LHA510 Proof-of-concept Study as a Maintenance Therapy for Patients With Wet Age-related Macular Degeneration).
Alflutinib	Alflutinib is under investigation in clinical trial NCT03452592 (Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients With T790M).
HIV Integrase Inhibitor	HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects).
Chiauranib	Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma).
Acetyldinaline	Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).
Lazertinib	Lazertinib is under investigation in clinical trial NCT04487080 (A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Levonadifloxacin	Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).
CC-11050	CC-11050 is under investigation in clinical trial NCT01300208 (To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus...
Nafithromycin	Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Nedisertib	Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer).
Nemiralisib	Nemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)).
Osoresnontrine	Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12...
Veliflapon	Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina).
Deucravacitinib	A TYK2 inhibitor being investigated as a treatment for psoriasis.
Belumosudil	An oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
MK-886	MK-886 is an experimental inhibitor of leukotriene synthesis.
Lavendustin A	Not Annotated
Methyl 2,5-dihydroxycinnamate	Not Annotated
Itanapraced	Not Annotated
Fadrozole	Not Annotated
AZD-7648	Not Annotated
Olprinone	Not Annotated
Rosmarinic acid	Not Annotated
AMG-319	Not Annotated
Leupeptin	Not Annotated
NP-51	Not Annotated
MRK-003	MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Arachidonyltrifluoromethane	Specific inhibitor of phospholipase A2.
Diphenyleneiodonium	An NADPH oxidase 2 (NOX2) inhibitor.
Ellipticine	Ellipticine is a potent antineoplastic agent.
Go-6976	An inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Homidium	Homidium is a group II compound with trypanocidal effects.
PD-169316	PD-169316 is a p38 MAP kinase inhibitor.
PD-98059	PD-98059 is an inhibitor of MAP-kinase kinase activation.
Scriptaid	Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.
TPCA-1	TPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).
U-0126	U-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.
Farudodstat	Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia).
Bromopyruvate	Not Annotated
KX-2361	Not Annotated
ONO-7579	Not Annotated
Olutasidenib	An isocitrate dehydrogenase-1 (IDH1) inhibitor indicated for the treatment of patients with relapsed or refractory acute myeloid leukemia with a susceptible IDH1 mutation as detected by an FDA-approved test.
Everolimus	A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.
Deracoxib	Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to...
Tivozanib	A kinase inhibitor to treat adult patients with renal cell carcinoma (RCC) who have failed prior systemic therapies or experienced relapsed disease.
Gepotidacin	Gepotidacin has been used in trials studying the treatment of Gonorrhea, Infections, Bacterial, and Infections, Respiratory Tract.
Zoliflodacin	Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Ozenoxacin	A quinolone antibiotic used to treat impetigo caused by susceptible bacteria.
Zatolmilast	BPN-14770 is under investigation in clinical trial NCT02840279 (A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects).
Venglustat	Venglustat is under investigation in clinical trial NCT01674036 (Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men).
Inavolisib	Inavolisib (GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine...
LB-100	LB-100 is under investigation in clinical trial NCT03886662 (A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)).
Fluzoparib	Fluzoparib is under investigation in clinical trial NCT03863860 (A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients).
GC-376 free acid	GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound...
Ibezapolstat	Ibezapolstat is under investigation in clinical trial NCT04247542 (ACX-362E Ibezapolstat for Oral Treatment of Clostridioides Difficile Infection).
Remibrutinib	Not Annotated
Pirtobrutinib	A kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy.
Ammonium tetrathiomolybdate	Not Annotated
Ajoene	Not Annotated
Ammonium trichlorotellurate	Ammonium trichlorotellurate is an investigational compound with anti-tumour and anti-inflammatory properties.
Aphidicolin	Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Recombinant Alpha-1-antitrypsin	Not Annotated
Durlobactam	Durlobactam is co-packaged with sulbactam as a single combination product, and is indicated for the treatment of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia caused by susceptible isolates of Acinetobacter...
5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine	Not Annotated
AUM-302	Not Annotated
Aloxistatin	Not Annotated
CTB001	CTB001 is an anti-claudin 18.2 autologous chimeric antigen receptor (CAR) T-cell therapy under investigation for the treatment of gastric cancers.
Fenvalerate	Not Annotated
DMP-777	DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Sodium arsenite	Not Annotated
Nilotinib	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Bosutinib	An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments.
Aliskiren	A direct renin inhibitor used to manage hypertension.
Ibrutinib	An antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
Alectinib	A kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
Acalabrutinib	A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
Neratinib	A protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor.
Dacomitinib	A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Gilteritinib	An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
Asciminib	An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation.
Quizartinib	A FLT3 inhibitor used in combination with cytarabine and anthracycline to treat acute myeloid leukemia with FLT3 internal tandem duplication
Mobocertinib	An oral kinase inhibitor targeted against EGFR and used in the treatment of NSCLC with EGFR exon 20 insertion mutations.

Drugs & Drug Targets

Drug	Target	Type
Lepirudin	Prothrombin	target
Bivalirudin	Prothrombin	target
Bivalirudin	Myeloperoxidase	enzyme
Alpha-1-proteinase inhibitor	Neutrophil elastase	target
Cyclosporine	Calcium signal-modulating cyclophilin ligand	target
Cyclosporine	Peptidyl-prolyl cis-trans isomerase A	target
Cyclosporine	Calcineurin subunit B type 2	target
Cyclosporine	Cytochrome P450 3A5	enzyme
Cyclosporine	Cytochrome P450 3A4	enzyme
Cyclosporine	P-glycoprotein 1	transporter
Cyclosporine	Bile salt export pump	transporter
Cyclosporine	Ileal sodium/bile acid cotransporter	transporter
Cyclosporine	Sodium/bile acid cotransporter	transporter
Cyclosporine	Solute carrier family 22 member 6	transporter
Cyclosporine	Multidrug resistance-associated protein 7	transporter
Cyclosporine	Canalicular multispecific organic anion transporter 1	transporter
Cyclosporine	ATP-binding cassette sub-family G member 2	transporter
Cyclosporine	Solute carrier organic anion transporter family member 1B1	transporter
Cyclosporine	Cytochrome P450 2C19	enzyme
Cyclosporine	Cytochrome P450 2D6	enzyme
Cyclosporine	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	target
Cyclosporine	Solute carrier organic anion transporter family member 1B3	transporter
Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Pravastatin	Solute carrier organic anion transporter family member 2B1	transporter
Pravastatin	P-glycoprotein 1	transporter
Pravastatin	Solute carrier organic anion transporter family member 1A2	transporter
Pravastatin	Solute carrier family 22 member 6	transporter
Pravastatin	Solute carrier family 22 member 8	transporter
Pravastatin	Canalicular multispecific organic anion transporter 1	transporter
Pravastatin	Solute carrier family 22 member 11	transporter
Pravastatin	ATP-binding cassette sub-family G member 2	transporter
Pravastatin	Solute carrier family 22 member 7	transporter
Pravastatin	Solute carrier organic anion transporter family member 1B1	transporter
Pravastatin	Monocarboxylate transporter 1	transporter
Pravastatin	Bile salt export pump	transporter
Pravastatin	Solute carrier organic anion transporter family member 1B3	transporter
Pravastatin	Histone deacetylase 2	target
Fluvoxamine	Sodium-dependent serotonin transporter	target
Fluvoxamine	Cytochrome P450 1A2	enzyme
Fluvoxamine	Cytochrome P450 2D6	enzyme
Fluvoxamine	Cytochrome P450 2C9	enzyme
Fluvoxamine	Cytochrome P450 2C19	enzyme
Fluvoxamine	Cytochrome P450 1A1	enzyme
Fluvoxamine	Cytochrome P450 3A4	enzyme
Fluvoxamine	Cytochrome P450 3A Subfamily	enzyme
Fluvoxamine	P-glycoprotein 1	transporter
Fluvoxamine	Cytochrome P450 2B6	enzyme
Fluvoxamine	Potassium voltage-gated channel subfamily H member 2	target
Fluvoxamine	Bile salt export pump	transporter
Ramipril	Angiotensin-converting enzyme	target
Ramipril	Solute carrier family 15 member 1	transporter
Ramipril	Solute carrier family 15 member 2	transporter
Ramipril	Cholinesterase	enzyme
Ramipril	B1 bradykinin receptor	target
Masoprocol	Arachidonate 5-lipoxygenase	target
Masoprocol	Sex hormone-binding globulin	target
Masoprocol	Transient receptor potential cation channel subfamily M member 7	target
Carbidopa	Aromatic-L-amino-acid decarboxylase	target
Fluconazole	Cytochrome P450 3A4	enzyme
Fluconazole	Cytochrome P450 2C9	enzyme
Fluconazole	Cytochrome P450 2C19	enzyme
Fluconazole	P-glycoprotein 1	transporter
Fluconazole	Cytochrome P450 51	target
Fluconazole	Cytochrome P450 3A5	enzyme
Erythromycin	23S ribosomal RNA	target
Erythromycin	Cytochrome P450 3A4	enzyme
Erythromycin	Cytochrome P450 3A7	enzyme
Erythromycin	P-glycoprotein 1	transporter
Erythromycin	Solute carrier organic anion transporter family member 1B1	transporter
Erythromycin	Motilin receptor	target
Erythromycin	Potassium voltage-gated channel subfamily H member 2	target
Erythromycin	Cytochrome P450 3A5	enzyme
Erythromycin	Solute carrier organic anion transporter family member 1B3	transporter
Erythromycin	Bile salt export pump	transporter
Erythromycin	Canalicular multispecific organic anion transporter 1	transporter
Erythromycin	Solute carrier organic anion transporter family member 1A2	transporter
Caffeine	Adenosine receptor A1	target
Caffeine	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Caffeine	Adenosine receptor A2a	target
Caffeine	Cytochrome P450 1A2	enzyme
Caffeine	Ryanodine receptor 1	target
Caffeine	Cytochrome P450 3A4	enzyme
Caffeine	Cytochrome P450 2E1	enzyme
Caffeine	Cytochrome P450 2C8	enzyme
Caffeine	Cytochrome P450 2C9	enzyme
Caffeine	Cytochrome P450 1A1	enzyme
Caffeine	Cytochrome P450 1B1	enzyme
Caffeine	Cytochrome P450 2D6	enzyme
Caffeine	Cyclic nucleotide phosphodiesterase	target
Caffeine	DNA-dependent protein kinase catalytic subunit	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	target
Caffeine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	target
Caffeine	Inositol 1,4,5-trisphosphate receptor	target
Caffeine	Serine-protein kinase ATM	target
Caffeine	ATP-binding cassette sub-family G member 2	transporter
Caffeine	Adenosine receptor A2b	target
Caffeine	Adenosine receptor A3	target
Caffeine	Phosphodiesterase enzymes	target
Sildenafil	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Sildenafil	Cytochrome P450 2C9	enzyme
Sildenafil	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	target
Sildenafil	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	target
Sildenafil	Cytochrome P450 3A4	enzyme
Sildenafil	Cytochrome P450 3A5	enzyme
Sildenafil	Cytochrome P450 3A7	enzyme
Sildenafil	Multidrug resistance-associated protein 4	transporter
Sildenafil	Multidrug resistance-associated protein 5	transporter
Sildenafil	Multidrug resistance-associated protein 7	transporter
Sildenafil	Cytochrome P450 2C19	enzyme
Sildenafil	Cytochrome P450 2D6	enzyme
Sildenafil	Cytochrome P450 2E1	enzyme
Sildenafil	Solute carrier organic anion transporter family member 1B1	transporter
Sildenafil	P-glycoprotein 1	transporter
Sildenafil	Ornithine decarboxylase	target
Sildenafil	Programmed cell death 1 ligand 1	target
Pyrimethamine	Bifunctional dihydrofolate reductase-thymidylate synthase	target
Pyrimethamine	Dihydrofolate reductase	target
Pyrimethamine	Cytochrome P450 2C8	enzyme
Pyrimethamine	Beta-hexosaminidase subunit beta	target
Pyrimethamine	Multidrug and toxin extrusion protein 1	transporter
Pyrimethamine	Multidrug and toxin extrusion protein 2	transporter
Remikiren	Renin	target
Pantoprazole	Potassium-transporting ATPase alpha chain 1	target
Pantoprazole	Cytochrome P450 2C19	enzyme
Pantoprazole	Cytochrome P450 3A4	enzyme
Pantoprazole	P-glycoprotein 1	transporter
Pantoprazole	ATP-binding cassette sub-family G member 2	transporter
Pantoprazole	Solute carrier family 22 member 8	transporter
Pantoprazole	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	target
Moxifloxacin	DNA gyrase subunit A	target
Moxifloxacin	DNA topoisomerase 4 subunit A	target
Moxifloxacin	DNA topoisomerase 2-alpha	target
Moxifloxacin	Cytochrome P450 1A2	enzyme
Moxifloxacin	Serum paraoxonase/arylesterase 1	target
Nelfinavir	HIV-1 protease	target
Nelfinavir	Cytochrome P450 2C19	enzyme
Nelfinavir	Cytochrome P450 3A4	enzyme
Nelfinavir	Cytochrome P450 2B6	enzyme
Nelfinavir	Cytochrome P450 3A5	enzyme
Nelfinavir	Cytochrome P450 3A7	enzyme
Nelfinavir	P-glycoprotein 1	transporter
Nelfinavir	Solute carrier family 22 member 1	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1A2	transporter
Nelfinavir	ATP-binding cassette sub-family G member 2	transporter
Nelfinavir	Solute carrier organic anion transporter family member 1B1	transporter
Nelfinavir	Cytochrome P450 2D6	enzyme
Nelfinavir	Serum albumin	carrier
Nelfinavir	UDP-glucuronosyltransferase 1-1	enzyme
Nelfinavir	Solute carrier organic anion transporter family member 1B3	transporter
Nelfinavir	Solute carrier organic anion transporter family member 2B1	transporter
Nelfinavir	Bile salt export pump	transporter
Nelfinavir	Cytochrome P450 2C9	enzyme
Nelfinavir	Alpha-1-acid glycoprotein 1	carrier
Indinavir	Human immunodeficiency virus type 1 protease	target
Indinavir	Cytochrome P450 3A4	enzyme
Indinavir	Cytochrome P450 3A5	enzyme
Indinavir	Cytochrome P450 3A7	enzyme
Indinavir	P-glycoprotein 1	transporter
Indinavir	Solute carrier family 22 member 1	transporter
Indinavir	Multidrug resistance-associated protein 1	transporter
Indinavir	Solute carrier organic anion transporter family member 1A2	transporter
Indinavir	Solute carrier organic anion transporter family member 1B1	transporter
Indinavir	Canalicular multispecific organic anion transporter 1	transporter
Indinavir	Cytochrome P450 2D6	enzyme
Indinavir	UDP-glucuronosyltransferase 1-1	enzyme
Indinavir	Solute carrier organic anion transporter family member 2B1	transporter
Indinavir	Bile salt export pump	transporter
Lovastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Lovastatin	Cytochrome P450 3A4	enzyme
Lovastatin	Cytochrome P450 2C8	enzyme
Lovastatin	Integrin alpha-L	target
Lovastatin	Histone deacetylase 2	target
Lovastatin	Serum paraoxonase/lactonase 3	enzyme
Lovastatin	P-glycoprotein 1	transporter
Lovastatin	Solute carrier organic anion transporter family member 1A2	transporter
Lovastatin	Solute carrier organic anion transporter family member 1B1	transporter
Lovastatin	UDP-glucuronosyltransferase 1-1	enzyme
Lovastatin	UDP-glucuronosyltransferase 1-3	enzyme
Lovastatin	UDP-glucuronosyltransferase 2B7	enzyme
Lovastatin	Canalicular multispecific organic anion transporter 1	transporter
Lovastatin	Bile salt export pump	transporter
Lovastatin	Serum albumin	carrier
Lovastatin	Cytochrome P450 2C19	enzyme
Lovastatin	Solute carrier organic anion transporter family member 2B1	transporter
Lovastatin	Solute carrier organic anion transporter family member 1B3	transporter
Milrinone	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Nevirapine	Cytochrome P450 3A4	enzyme
Nevirapine	Cytochrome P450 2B6	enzyme
Nevirapine	Cytochrome P450 3A5	enzyme
Nevirapine	Cytochrome P450 2C9	enzyme
Nevirapine	Cytochrome P450 2A6	enzyme
Nevirapine	Cytochrome P450 2D6	enzyme
Nevirapine	Reverse transcriptase/RNaseH	target
Nevirapine	Serum albumin	carrier
Nevirapine	Cytochrome P450 1A2	enzyme
Nevirapine	Solute carrier family 22 member 1	transporter
Nevirapine	Cytochrome P450 3A7	enzyme
Clotrimazole	Intermediate conductance calcium-activated potassium channel protein 4	target
Clotrimazole	Cytochrome P450 2D6	enzyme
Clotrimazole	Cytochrome P450 2C8	enzyme
Clotrimazole	Cytochrome P450 3A4	enzyme
Clotrimazole	Cytochrome P450 2B6	enzyme
Clotrimazole	P-glycoprotein 1	transporter
Clotrimazole	Cytochrome P450 2A6	enzyme
Clotrimazole	Cytochrome P450 2C9	enzyme
Clotrimazole	Cytochrome P450 2E1	enzyme
Clotrimazole	Cytochrome P450 3A7	enzyme
Clotrimazole	Cytochrome P450 51	target
Clotrimazole	Nuclear receptor subfamily 1 group I member 2	target
Clotrimazole	Hydroxycarboxylic acid receptor 2	target
Clotrimazole	Bile salt export pump	transporter
Clotrimazole	Solute carrier organic anion transporter family member 1B1	transporter
Clotrimazole	Solute carrier organic anion transporter family member 1B3	transporter
Clotrimazole	Ergosterol	target
Dicoumarol	Vitamin K epoxide reductase complex subunit 1	target
Dicoumarol	NAD(P)H dehydrogenase [quinone] 1	target
Dicoumarol	Quinone oxidoreductase	target
Dicoumarol	Cytochrome P450 2C9	enzyme
Dicoumarol	Serum albumin	carrier
Dicoumarol	Cytochrome P450 2C6	enzyme
Dicoumarol	Cytochrome P450 2C11	enzyme
Theophylline	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Theophylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Theophylline	Adenosine receptor A2b	target
Theophylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Theophylline	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Theophylline	Adenosine receptor A1	target
Theophylline	Adenosine receptor A2a	target
Theophylline	Cytochrome P450 1A2	enzyme
Theophylline	Adenosine deaminase	enzyme
Theophylline	Cytochrome P450 2E1	enzyme
Theophylline	Cytochrome P450 3A4	enzyme
Theophylline	Solute carrier family 22 member 7	transporter
Theophylline	Cytochrome P450 1A1	enzyme
Theophylline	Cytochrome P450 1B1	enzyme
Theophylline	Cytochrome P450 2D6	enzyme
Theophylline	Histone deacetylase 2	target
Theophylline	Copine-1	target
Theophylline	Minor histocompatibility antigen H13	target
Theophylline	Nodal modulator 1	target
Theophylline	Poly [ADP-ribose] polymerase 1	target
Theophylline	Protein RIC-3	target
Theophylline	Tubulin monoglycylase TTLL3	target
Argatroban	Prothrombin	target
Argatroban	Cytochrome P450 3A4	enzyme
Argatroban	Cytochrome P450 3A5	enzyme
Argatroban	Serum albumin	carrier
Argatroban	alpha1-acid glycoprotein	carrier
Acarbose	Maltase-glucoamylase, intestinal	target
Acarbose	Lysosomal alpha-glucosidase	target
Acarbose	Sucrase-isomaltase, intestinal	target
Acarbose	Pancreatic alpha-amylase	target
Mitomycin	DNA	target
Mitomycin	NADPH--cytochrome P450 reductase	enzyme
Valproic acid	Histone deacetylase 9	target
Valproic acid	Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial	target
Valproic acid	Cytochrome P450 2A6	enzyme
Valproic acid	Cytochrome P450 2B6	enzyme
Valproic acid	Cytochrome P450 2C9	enzyme
Valproic acid	Solute carrier family 22 member 5	transporter
Valproic acid	Solute carrier family 22 member 6	transporter
Valproic acid	Solute carrier family 22 member 8	transporter
Valproic acid	Monocarboxylate transporter 1	transporter
Valproic acid	Solute carrier family 22 member 7	transporter
Valproic acid	Cytochrome P450 3A5	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-9	enzyme
Valproic acid	Prostaglandin G/H synthase 1	enzyme
Valproic acid	Cytochrome P450 1A2	enzyme
Valproic acid	Cytochrome P450 2C19	enzyme
Valproic acid	Cytochrome P450 3A4	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-4	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-8	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-10	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-6	enzyme
Valproic acid	UDP-glucuronosyltransferase 1-3	enzyme
Valproic acid	UDP-glucuronosyltransferase 2B7	enzyme
Valproic acid	UDP-glucuronosyltransferase 2B15	enzyme
Valproic acid	2-oxoglutarate dehydrogenase, mitochondrial	target
Valproic acid	Succinate-semialdehyde dehydrogenase, mitochondrial	target
Valproic acid	Sodium channel protein	target
Valproic acid	Histone deacetylase 2	target
Valproic acid	Peroxisome proliferator-activated receptor alpha	target
Valproic acid	Peroxisome proliferator-activated receptor delta	target
Valproic acid	Peroxisome proliferator-activated receptor gamma	target
Valproic acid	Serum albumin	carrier
Valproic acid	UDP-glucuronosyltransferase 1-1	enzyme
Valproic acid	Solute carrier organic anion transporter family member 2B1	transporter
Valproic acid	Histone deacetylase	target
Valproic acid	Cyclin-dependent kinase inhibitor 1	target
Valproic acid	Hepatocyte growth factor	target
Valproic acid	Ornithine decarboxylase	target
Valproic acid	Programmed cell death 1 ligand 1	target
Gefitinib	Epidermal growth factor receptor	target
Gefitinib	Cytochrome P450 3A4	enzyme
Gefitinib	Cytochrome P450 2D6	enzyme
Gefitinib	P-glycoprotein 1	transporter
Gefitinib	ATP-binding cassette sub-family G member 2	transporter
Gefitinib	Cytochrome P450 3A5	enzyme
Gefitinib	Cytochrome P450 1A1	enzyme
Gefitinib	Cytochrome P450 2C9	enzyme
Gefitinib	Cytochrome P450 2C19	enzyme
Gefitinib	Serum albumin	carrier
Gefitinib	Alpha-1-acid glycoprotein 1	carrier
Tolcapone	Catechol O-methyltransferase	target
Tolcapone	Cytochrome P450 2C9	enzyme
Indomethacin	Prostaglandin G/H synthase 1	target
Indomethacin	Prostaglandin G/H synthase 2	target
Indomethacin	Cytochrome P450 2C19	enzyme
Indomethacin	UDP-glucuronosyltransferase 1-9	enzyme
Indomethacin	Phospholipase A2, membrane associated	target
Indomethacin	Prostaglandin reductase 2	target
Indomethacin	Lactoylglutathione lyase	target
Indomethacin	Prostaglandin D2 receptor 2	target
Indomethacin	Peroxisome proliferator-activated receptor gamma	target
Indomethacin	Serum albumin	carrier
Indomethacin	Canalicular multispecific organic anion transporter 2	transporter
Indomethacin	Multidrug resistance-associated protein 4	transporter
Indomethacin	Multidrug resistance-associated protein 6	transporter
Indomethacin	P-glycoprotein 1	transporter
Indomethacin	Multidrug resistance-associated protein 1	transporter
Indomethacin	Solute carrier organic anion transporter family member 1A2	transporter
Indomethacin	Solute carrier family 22 member 6	transporter
Indomethacin	Solute carrier family 22 member 8	transporter
Indomethacin	Canalicular multispecific organic anion transporter 1	transporter
Indomethacin	ATP-binding cassette sub-family C member 11	transporter
Indomethacin	Solute carrier family 22 member 11	transporter
Indomethacin	Sodium/bile acid cotransporter	transporter
Indomethacin	Solute carrier family 22 member 7	transporter
Indomethacin	Cytochrome P450 2C9	enzyme
Indomethacin	UDP-glucuronosyltransferase 1-1	enzyme
Indomethacin	Liver carboxylesterase 1	enzyme
Indomethacin	UDP-glucuronosyltransferase 2B7	enzyme
Indomethacin	Peroxisome proliferator-activated receptor alpha	target
Indomethacin	Aldo-keto reductase family 1 member C3	target
Indomethacin	Solute carrier organic anion transporter family member 1B1	transporter
Indomethacin	Bile salt export pump	transporter
Indomethacin	Interferon-induced, double-stranded RNA-activated protein kinase	target
Indomethacin	Human Cyclooxygenases	target
Omeprazole	Potassium-transporting ATPase alpha chain 1	target
Omeprazole	Cytochrome P450 2C19	enzyme
Omeprazole	Cytochrome P450 3A4	enzyme
Omeprazole	Cytochrome P450 2C9	enzyme
Omeprazole	Cytochrome P450 1A2	enzyme
Omeprazole	Canalicular multispecific organic anion transporter 2	transporter
Omeprazole	P-glycoprotein 1	transporter
Omeprazole	ATP-binding cassette sub-family G member 2	transporter
Omeprazole	Cytochrome P450 1A1	enzyme
Omeprazole	Cytochrome P450 1B1	enzyme
Omeprazole	Cytochrome P450 2C18	enzyme
Omeprazole	Cytochrome P450 2C8	enzyme
Omeprazole	Cytochrome P450 2D6	enzyme
Omeprazole	Aryl hydrocarbon receptor	target
Nitisinone	4-hydroxyphenylpyruvate dioxygenase	target
Aminoglutethimide	Cytochrome P450 19A1	target
Aminoglutethimide	Cytochrome P450 2C19	enzyme
Aminoglutethimide	Cytochrome P450 3A4	enzyme
Aminoglutethimide	Cholesterol side-chain cleavage enzyme, mitochondrial	target
Mupirocin	Isoleucine--tRNA ligase	target
Allopurinol	Xanthine dehydrogenase/oxidase	target
Allopurinol	Solute carrier family 22 member 8	transporter
Allopurinol	Solute carrier family 22 member 7	transporter
Allopurinol	Aldehyde oxidase	enzyme
Allopurinol	Xanthine dehydrogenase/oxidase	enzyme
Allopurinol	ATP-binding cassette sub-family G member 2	transporter
Allopurinol	Solute carrier family 22 member 2	transporter
Trimethoprim	Dihydrofolate reductase	target
Trimethoprim	Cytochrome P450 2C8	enzyme
Trimethoprim	Cytochrome P450 3A4	enzyme
Trimethoprim	P-glycoprotein 1	transporter
Trimethoprim	Cytochrome P450 2C9	enzyme
Trimethoprim	Cytochrome P450 1A2	enzyme
Trimethoprim	Multidrug and toxin extrusion protein 1	transporter
Trimethoprim	Multidrug and toxin extrusion protein 2	transporter
Gemcitabine	Ribonucleoside-diphosphate reductase large subunit	target
Gemcitabine	UMP-CMP kinase	target
Gemcitabine	Thymidylate synthase	target
Gemcitabine	Cytidine deaminase	enzyme
Gemcitabine	Deoxycytidine kinase	enzyme
Gemcitabine	P-glycoprotein 1	transporter
Gemcitabine	Multidrug resistance-associated protein 7	transporter
Gemcitabine	Equilibrative nucleoside transporter 1	transporter
Gemcitabine	DNA	target
Gemcitabine	Sodium/nucleoside cotransporter 1	transporter
Gemcitabine	Equilibrative nucleoside transporter 2	transporter
Gemcitabine	Solute carrier family 28 member 3	transporter
Gemcitabine	Thymidine kinase 2, mitochondrial	enzyme
Gemcitabine	UMP-CMP kinase	enzyme
Gemcitabine	Nucleoside diphosphate kinase A	enzyme
Chloramphenicol	Complement decay-accelerating factor	target
Chloramphenicol	Dr hemagglutinin structural subunit	target
Chloramphenicol	Cytochrome P450 2C19	enzyme
Chloramphenicol	Cytochrome P450 3A4	enzyme
Chloramphenicol	Cytochrome P450 3A5	enzyme
Chloramphenicol	Cytochrome P450 3A7	enzyme
Chloramphenicol	Solute carrier family 22 member 6	transporter
Chloramphenicol	50S ribosomal protein L16	target
Chloramphenicol	Chloramphenicol acetyltransferase 3	enzyme
Chloramphenicol	Chloramphenicol acetyltransferase	enzyme
Chloramphenicol	Chloramphenicol 3-O phosphotransferase	enzyme
Nabumetone	Prostaglandin G/H synthase 1	target
Nabumetone	Prostaglandin G/H synthase 2	target
Nabumetone	Myeloperoxidase	enzyme
Nabumetone	Cytochrome P450 1A2	enzyme
Nabumetone	Cytochrome P450 2C9	enzyme
Nabumetone	Corticosteroid 11-beta-dehydrogenase isozyme 1	enzyme
Nabumetone	Aldo-keto reductase family 1 member C1	enzyme
Nabumetone	Aldo-keto reductase family 1 member C2	enzyme
Nabumetone	Aldo-keto reductase family 1 member C4	enzyme
Nabumetone	Serum albumin	carrier
Ketorolac	Prostaglandin G/H synthase 1	target
Ketorolac	Prostaglandin G/H synthase 2	target
Ketorolac	UDP-glucuronosyltransferase 2B7	enzyme
Ketorolac	Cytochrome P450 2C8	enzyme
Ketorolac	Cytochrome P450 2C9	enzyme
Enoxacin	DNA gyrase subunit A	target
Enoxacin	DNA topoisomerase 4 subunit A	target
Enoxacin	DNA topoisomerase 2-alpha	target
Enoxacin	Cytochrome P450 1A2	enzyme
Fluoxetine	Sodium-dependent serotonin transporter	target
Fluoxetine	Cytochrome P450 2C9	enzyme
Fluoxetine	Cytochrome P450 2D6	enzyme
Fluoxetine	CYP2B protein	enzyme
Fluoxetine	Cytochrome P450 1A2	enzyme
Fluoxetine	Cytochrome P450 3A4	enzyme
Fluoxetine	Cytochrome P450 2C19	enzyme
Fluoxetine	P-glycoprotein 1	transporter
Fluoxetine	Cytochrome P450 2B6	enzyme
Fluoxetine	Cytochrome P450 3A5	enzyme
Fluoxetine	Serum albumin	carrier
Fluoxetine	Alpha-1-acid glycoprotein 1	carrier
Fluoxetine	Potassium voltage-gated channel subfamily H member 2	target
Fluoxetine	5-hydroxytryptamine receptor 2C	target
Fluoxetine	Cyclin-dependent kinases regulatory subunit 1	target
Fluoxetine	Neuronal acetylcholine receptor subunit alpha-2	target
Fluoxetine	Neuronal acetylcholine receptor subunit alpha-3	target
Fluoxetine	Neuronal acetylcholine receptor subunit beta-4	target
Celecoxib	Prostaglandin G/H synthase 2	target
Celecoxib	3-phosphoinositide-dependent protein kinase 1	target
Celecoxib	Cytochrome P450 2C9	enzyme
Celecoxib	Cytochrome P450 2D6	enzyme
Celecoxib	Multidrug resistance-associated protein 4	transporter
Celecoxib	Cytochrome P450 3A4	enzyme
Celecoxib	Cytochrome P450 2C8	enzyme
Celecoxib	Carbonic anhydrase 2	target
Celecoxib	Carbonic anhydrase 3	target
Celecoxib	Bile salt export pump	transporter
Celecoxib	Cadherin-11	target
Celecoxib	P-glycoprotein 1	transporter
Celecoxib	ATP-binding cassette sub-family G member 2	transporter
Celecoxib	Prostaglandin G/H synthase 2	enzyme
Celecoxib	Sialidase-1	target
Miglitol	Maltase-glucoamylase, intestinal	target
Miglitol	Pancreatic alpha-amylase	enzyme
Miglitol	Lysosomal alpha-glucosidase	target
Miglitol	Neutral alpha-glucosidase AB	target
Miglitol	Neutral alpha-glucosidase C	target
Fosinopril	Angiotensin-converting enzyme	target
Fosinopril	Solute carrier family 15 member 1	transporter
Fosinopril	Solute carrier family 15 member 2	transporter
Entacapone	Catechol O-methyltransferase	target
Entacapone	Catechol O-methyltransferase	enzyme
Entacapone	UDP-glucuronosyltransferase 1-9	enzyme
Entacapone	Cytochrome P450 2D6	enzyme
Zidovudine	Serum albumin	carrier
Zidovudine	Cytochrome P450 2A6	enzyme
Zidovudine	Cytochrome P450 2C9	enzyme
Zidovudine	Cytochrome P450 3A4	enzyme
Zidovudine	Reverse transcriptase/RNaseH	target
Zidovudine	Solute carrier family 22 member 2	transporter
Zidovudine	Solute carrier family 22 member 6	transporter
Zidovudine	Solute carrier family 22 member 7	transporter
Zidovudine	Solute carrier family 22 member 8	transporter
Zidovudine	Solute carrier family 22 member 11	transporter
Zidovudine	Sodium/nucleoside cotransporter 1	transporter
Zidovudine	Equilibrative nucleoside transporter 2	transporter
Zidovudine	P-glycoprotein 1	transporter
Zidovudine	Multidrug resistance-associated protein 4	transporter
Zidovudine	Multidrug resistance-associated protein 5	transporter
Zidovudine	ATP-binding cassette sub-family G member 2	transporter
Zidovudine	Telomerase reverse transcriptase	target
Zidovudine	Thymidine kinase, cytosolic	enzyme
Zidovudine	UDP-glucuronosyltransferase 2B7	enzyme
Zidovudine	UDP-glucuronosyltransferase 1-1	enzyme
Cimetidine	Histamine H2 receptor	target
Cimetidine	Cytochrome P450 1A2	enzyme
Cimetidine	Cytochrome P450 2D6	enzyme
Cimetidine	Cytochrome P450 2C19	enzyme
Cimetidine	Cytochrome P450 3A4	enzyme
Cimetidine	Cytochrome P450 3A5	enzyme
Cimetidine	P-glycoprotein 1	transporter
Cimetidine	Solute carrier family 22 member 2	transporter
Cimetidine	Solute carrier family 22 member 1	transporter
Cimetidine	Solute carrier family 22 member 3	transporter
Cimetidine	Solute carrier family 22 member 5	transporter
Cimetidine	Solute carrier family 22 member 6	transporter
Cimetidine	Solute carrier family 22 member 8	transporter
Cimetidine	Multidrug and toxin extrusion protein 1	transporter
Cimetidine	Solute carrier family 22 member 4	transporter
Cimetidine	Solute carrier family 22 member 11	transporter
Cimetidine	Solute carrier family 22 member 7	transporter
Cimetidine	Cytochrome P450 11B1, mitochondrial	enzyme
Cimetidine	Cytochrome P450 2C8	enzyme
Cimetidine	Cytochrome P450 2C9	enzyme
Cimetidine	Cytochrome P450 2E1	enzyme
Cimetidine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Cimetidine	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Cimetidine	Bile salt export pump	transporter
Cimetidine	Multidrug and toxin extrusion protein 2	transporter
Cimetidine	Serum albumin	carrier
Ritonavir	Human immunodeficiency virus type 1 protease	target
Ritonavir	Cytochrome P450 2D6	enzyme
Ritonavir	Cytochrome P450 2C9	enzyme
Ritonavir	Cytochrome P450 2C19	enzyme
Ritonavir	Cytochrome P450 2B6	enzyme
Ritonavir	Cytochrome P450 2C8	enzyme
Ritonavir	P-glycoprotein 1	transporter
Ritonavir	Multidrug resistance-associated protein 1	transporter
Ritonavir	Canalicular multispecific organic anion transporter 1	transporter
Ritonavir	Solute carrier organic anion transporter family member 1A2	transporter
Ritonavir	ATP-binding cassette sub-family G member 2	transporter
Ritonavir	Solute carrier organic anion transporter family member 1B1	transporter
Ritonavir	Cytochrome P450 1A2	enzyme
Ritonavir	Nuclear receptor subfamily 1 group I member 2	target
Ritonavir	Serum albumin	carrier
Ritonavir	Cytochrome P450 3A4	enzyme
Ritonavir	Cytochrome P450 3A5	enzyme
Ritonavir	Cytochrome P450 3A7	enzyme
Ritonavir	UDP-glucuronosyltransferases (UGTs)	enzyme
Ritonavir	Solute carrier organic anion transporter family member 2B1	transporter
Ritonavir	Bile salt export pump	transporter
Ritonavir	Alpha-1-acid glycoprotein 1	carrier
Ritonavir	Solute carrier organic anion transporter family member 1B3	transporter
Trandolapril	Angiotensin-converting enzyme	target
Trandolapril	Solute carrier family 15 member 1	transporter
Trandolapril	Solute carrier family 15 member 2	transporter
Trandolapril	Liver carboxylesterase 1	enzyme
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	DNA topoisomerase 4 subunit A	target
Ciprofloxacin	DNA topoisomerase 2-alpha	target
Ciprofloxacin	Cytochrome P450 1A2	enzyme
Ciprofloxacin	Cytochrome P450 3A4	enzyme
Ciprofloxacin	Cytochrome P450 3A5	enzyme
Ciprofloxacin	Cytochrome P450 3A7	enzyme
Ciprofloxacin	P-glycoprotein 1	transporter
Ciprofloxacin	Potassium voltage-gated channel subfamily H member 2	target
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	DNA topoisomerase 4 subunit A	target
Ciprofloxacin	DNA topoisomerase 4 subunit B	target
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	Multidrug resistance protein MdtK	target
Ciprofloxacin	Gyrase A	target
Ciprofloxacin	DNA gyrase subunit A	target
Ciprofloxacin	Multidrug and toxin extrusion protein 1	transporter
Ciprofloxacin	Multidrug and toxin extrusion protein 2	transporter
Ciprofloxacin	Serum albumin	carrier
Benazepril	Angiotensin-converting enzyme	target
Benazepril	Methylenetetrahydrofolate reductase	enzyme
Benazepril	Solute carrier family 15 member 1	transporter
Benazepril	Solute carrier family 15 member 2	transporter
Pyridostigmine	Acetylcholinesterase	target
Pyridostigmine	Cholinesterase	target
Pyridostigmine	Acetylcholinesterase	enzyme
Pyridostigmine	Cholinesterase	enzyme
Pyridostigmine	Cytochrome P450 3A4	enzyme
Acetohydroxamic acid	Urease subunit alpha	target
Acetohydroxamic acid	Macrophage metalloelastase	target
Zanamivir	Neuraminidase	target
Zanamivir	Neuraminidase	target
Zanamivir	Sialidase-2	target
Methotrexate	Dihydrofolate reductase	target
Methotrexate	Aldehyde oxidase	enzyme
Methotrexate	Methylenetetrahydrofolate reductase	enzyme
Methotrexate	Serum albumin	carrier
Methotrexate	Canalicular multispecific organic anion transporter 2	transporter
Methotrexate	Multidrug resistance-associated protein 4	transporter
Methotrexate	Multidrug resistance-associated protein 1	transporter
Methotrexate	Solute carrier family 22 member 6	transporter
Methotrexate	Multidrug resistance-associated protein 7	transporter
Methotrexate	Solute carrier family 22 member 8	transporter
Methotrexate	Canalicular multispecific organic anion transporter 1	transporter
Methotrexate	P-glycoprotein 1	transporter
Methotrexate	Solute carrier organic anion transporter family member 1A2	transporter
Methotrexate	Monocarboxylate transporter 1	transporter
Methotrexate	ATP-binding cassette sub-family C member 11	transporter
Methotrexate	Solute carrier organic anion transporter family member 1B3	transporter
Methotrexate	Solute carrier family 22 member 11	transporter
Methotrexate	Solute carrier organic anion transporter family member 1C1	transporter
Methotrexate	Solute carrier organic anion transporter family member 3A1	transporter
Methotrexate	ATP-binding cassette sub-family G member 2	transporter
Methotrexate	Solute carrier family 22 member 7	transporter
Methotrexate	Solute carrier organic anion transporter family member 1B1	transporter
Methotrexate	6-phosphogluconate dehydrogenase, decarboxylating	enzyme
Methotrexate	Proton-coupled folate transporter	transporter
Methotrexate	Folylpolyglutamate synthase, mitochondrial	enzyme
Methotrexate	Gamma-glutamyl hydrolase	enzyme
Methotrexate	Dihydrofolate reductase	enzyme
Methotrexate	Thymidylate synthase	enzyme
Methotrexate	Bifunctional purine biosynthesis protein PURH	enzyme
Methotrexate	Solute carrier organic anion transporter family member 4C1	transporter
Methotrexate	Folate transporter 1	transporter
Methotrexate	Folate receptor alpha	transporter
Methotrexate	Cytochrome P450 3A4	enzyme
Methotrexate	Thymidylate synthase	target
Methotrexate	Bifunctional purine biosynthesis protein PURH	target
Methotrexate	Folate receptor beta	transporter
Methotrexate	Solute carrier family 15 member 1	transporter
Methotrexate	Proton-coupled amino acid transporter 1	transporter
Methotrexate	Carboxypeptidase G2	enzyme
Voriconazole	Cytochrome P450 2C19	enzyme
Voriconazole	Cytochrome P450 3A4	enzyme
Voriconazole	Cytochrome P450 2C9	enzyme
Voriconazole	Dimethylaniline monooxygenase [N-oxide-forming] 1	enzyme
Voriconazole	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Voriconazole	Cytochrome P450 3A5	enzyme
Voriconazole	Cytochrome P450 3A7	enzyme
Voriconazole	Prostaglandin G/H synthase 1	enzyme
Voriconazole	Cytochrome P450 51	target
Voriconazole	Cytochrome P450 2B6	enzyme
Enalapril	Angiotensin-converting enzyme	target
Enalapril	P-glycoprotein 1	transporter
Enalapril	Solute carrier family 15 member 1	transporter
Enalapril	Solute carrier family 22 member 6	transporter
Enalapril	Solute carrier family 22 member 8	transporter
Enalapril	Solute carrier family 22 member 7	transporter
Enalapril	Solute carrier organic anion transporter family member 1A2	transporter
Enalapril	Serum albumin	carrier
Diclofenac	Prostaglandin G/H synthase 1	target
Diclofenac	Prostaglandin G/H synthase 2	target
Diclofenac	Transthyretin	carrier
Diclofenac	Cytochrome P450 2C9	enzyme
Diclofenac	Cytochrome P450 2C19	enzyme
Diclofenac	Cytochrome P450 1A2	enzyme
Diclofenac	Cytochrome P450 2C8	enzyme
Diclofenac	Serum albumin	carrier
Diclofenac	Multidrug resistance-associated protein 4	transporter
Diclofenac	Multidrug resistance-associated protein 1	transporter
Diclofenac	Solute carrier family 22 member 6	transporter
Diclofenac	Solute carrier family 22 member 8	transporter
Diclofenac	Solute carrier organic anion transporter family member 1C1	transporter
Diclofenac	Solute carrier family 22 member 11	transporter
Diclofenac	UDP-glucuronosyltransferase 2B7	enzyme
Diclofenac	Cytochrome P450 3A4	enzyme
Diclofenac	Cytochrome P450 2B6	enzyme
Diclofenac	Cytochrome P450 2C18	enzyme
Diclofenac	Cytochrome P450 2E1	enzyme
Diclofenac	Solute carrier organic anion transporter family member 1B1	transporter
Diclofenac	Bile salt export pump	transporter
Diclofenac	UDP-glucuronosyltransferase 1-3	enzyme
Diclofenac	UDP-glucuronosyltransferase 1-9	enzyme
Diclofenac	UDP-glucuronosyltransferase 2B4	enzyme
Diclofenac	Arachidonate 5-lipoxygenase	enzyme
Diclofenac	Sodium channel protein type 4 subunit alpha	transporter
Diclofenac	Acid-sensing ion channel 1	transporter
Diclofenac	Potassium voltage-gated channel subfamily KQT member 2	transporter
Diclofenac	Potassium voltage-gated channel subfamily KQT member 3	transporter
Diclofenac	Phospholipase A2, membrane associated	enzyme
Diclofenac	P-glycoprotein 1	transporter
Linezolid	23S ribosomal RNA	target
Linezolid	Amine oxidase [flavin-containing] A	enzyme
Linezolid	Amine oxidase [flavin-containing] B	enzyme
Linezolid	Serum albumin	carrier
Linezolid	Solute carrier family 22 member 6	transporter
Linezolid	Solute carrier family 22 member 8	transporter
Candoxatril	Neprilysin	target
Candoxatril	Angiotensin-converting enzyme	target
Imatinib	Platelet-derived growth factor receptor beta	target
Imatinib	Tyrosine-protein kinase ABL1	target
Imatinib	Mast/stem cell growth factor receptor Kit	target
Imatinib	RET proto-oncogene	target
Imatinib	High affinity nerve growth factor receptor	target
Imatinib	Macrophage colony-stimulating factor 1 receptor	target
Imatinib	Platelet-derived growth factor receptor alpha	target
Imatinib	Epithelial discoidin domain-containing receptor 1	target
Imatinib	Cytochrome P450 3A4	enzyme
Imatinib	Breakpoint cluster region protein	target
Imatinib	Cytochrome P450 1A2	enzyme
Imatinib	Cytochrome P450 2D6	enzyme
Imatinib	Cytochrome P450 2C9	enzyme
Imatinib	Cytochrome P450 2C19	enzyme
Imatinib	Cytochrome P450 3A5	enzyme
Imatinib	Cytochrome P450 3A7	enzyme
Imatinib	Solute carrier family 22 member 1	transporter
Imatinib	P-glycoprotein 1	transporter
Imatinib	Solute carrier family 22 member 2	transporter
Imatinib	ATP-binding cassette sub-family G member 2	transporter
Imatinib	ATP-binding cassette sub-family A member 3	transporter
Imatinib	Serum albumin	carrier
Imatinib	Alpha-1-acid glycoprotein 1	carrier
Imatinib	Bile salt export pump	transporter
Imatinib	Cytochrome P450 2C8	enzyme
Imatinib	Canalicular multispecific organic anion transporter 1	transporter
Imatinib	Multidrug resistance-associated protein 1	transporter
Imatinib	Solute carrier family 22 member 5	transporter
Imatinib	Solute carrier organic anion transporter family member 1B3	transporter
Imatinib	Multidrug resistance-associated protein 4	transporter
Imatinib	Solute carrier organic anion transporter family member 1A2	transporter
Imatinib	Discoidin domain-containing receptor 2	target
Triamcinolone	Corticosteroid-binding globulin	carrier
Triamcinolone	Glucocorticoid receptor	target
Triamcinolone	Cytochrome P450 3A4	enzyme
Triamcinolone	Prostaglandin G/H synthase 2	enzyme
Triamcinolone	Cholinesterase	enzyme
Triamcinolone	Cytochrome P450 3A5	enzyme
Triamcinolone	Cytochrome P450 3A7	enzyme
Triamcinolone	Serum albumin	carrier
Efavirenz	Cytochrome P450 2B6	enzyme
Efavirenz	Cytochrome P450 3A4	enzyme
Efavirenz	Cytochrome P450 2C19	enzyme
Efavirenz	Cytochrome P450 2C9	enzyme
Efavirenz	Cytochrome P450 1A2	enzyme
Efavirenz	Cytochrome P450 2D6	enzyme
Efavirenz	Reverse transcriptase/RNaseH	target
Efavirenz	Cytochrome P450 2C8	enzyme
Efavirenz	Serum albumin	carrier
Efavirenz	Cytochrome P450 3A5	enzyme
Efavirenz	Cytochrome P450 3A7	enzyme
Efavirenz	UDP-glucuronosyltransferase 1-1	enzyme
Efavirenz	Bile salt export pump	transporter
Efavirenz	Solute carrier family 22 member 1	transporter
Simvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Simvastatin	Cytochrome P450 3A4	enzyme
Simvastatin	Cytochrome P450 2C8	enzyme
Simvastatin	Cytochrome P450 2C9	enzyme
Simvastatin	Cytochrome P450 3A5	enzyme
Simvastatin	P-glycoprotein 1	transporter
Simvastatin	Solute carrier organic anion transporter family member 1A2	transporter
Simvastatin	Solute carrier organic anion transporter family member 1B1	transporter
Simvastatin	Cytochrome P450 2B6	enzyme
Simvastatin	Cytochrome P450 2D6	enzyme
Simvastatin	UDP-glucuronosyltransferase 1-1	enzyme
Simvastatin	UDP-glucuronosyltransferase 1-3	enzyme
Simvastatin	UDP-glucuronosyltransferase 2B7	enzyme
Simvastatin	Canalicular multispecific organic anion transporter 1	transporter
Simvastatin	Integrin alpha-L	target
Simvastatin	Bile salt export pump	transporter
Simvastatin	Cytochrome P450 2C19	enzyme
Simvastatin	Solute carrier organic anion transporter family member 2B1	transporter
Simvastatin	Solute carrier organic anion transporter family member 1B3	transporter
Simvastatin	Histone deacetylase 2	target
Simvastatin	Cocaine esterase	enzyme
Simvastatin	Liver carboxylesterase 1	enzyme
Galantamine	Acetylcholinesterase	target
Galantamine	Cytochrome P450 3A4	enzyme
Galantamine	Cytochrome P450 2D6	enzyme
Galantamine	Cholinesterase	target
Galantamine	P-glycoprotein 1	transporter
Galantamine	Neuronal acetylcholine receptor subunit alpha-7	target
Galantamine	Muscle nicotinic acetylcholine receptor	target
Isoflurophate	Cholinesterase	target
Isoflurophate	Acetylcholinesterase	target
Isoflurophate	Cholinesterase	enzyme
Isoflurophate	Serum albumin	carrier
Isoflurophate	Serotransferrin	target
Moexipril	Angiotensin-converting enzyme	target
Moexipril	Solute carrier family 15 member 1	transporter
Moexipril	Solute carrier family 15 member 2	transporter
Daunorubicin	DNA	target
Daunorubicin	Cytochrome P450 3A5	enzyme
Daunorubicin	NADPH--cytochrome P450 reductase	enzyme
Daunorubicin	P-glycoprotein 1	transporter
Daunorubicin	Multidrug resistance-associated protein 1	transporter
Daunorubicin	Multidrug resistance-associated protein 6	transporter
Daunorubicin	Multidrug resistance-associated protein 7	transporter
Daunorubicin	ATP-binding cassette sub-family G member 2	transporter
Daunorubicin	DNA topoisomerase 2-alpha	target
Daunorubicin	DNA topoisomerase 2-beta	target
Daunorubicin	Cytochrome P450 1B1	enzyme
Daunorubicin	Cytochrome P450 3A4	enzyme
Daunorubicin	Aldose reductase	enzyme
Daunorubicin	Carbonyl reductase [NADPH] 1	enzyme
Daunorubicin	Carbonyl reductase [NADPH] 3	enzyme
Amprenavir	Human immunodeficiency virus type 1 protease	target
Amprenavir	Cytochrome P450 3A4	enzyme
Amprenavir	P-glycoprotein 1	transporter
Amprenavir	Multidrug resistance-associated protein 1	transporter
Amprenavir	Cytochrome P450 2B6	enzyme
Amprenavir	Cytochrome P450 2C19	enzyme
Amprenavir	Cytochrome P450 2C9	enzyme
Amprenavir	Cytochrome P450 2D6	enzyme
Amprenavir	Cytochrome P450 3A5	enzyme
Amprenavir	Solute carrier organic anion transporter family member 1B1	transporter
Methazolamide	Carbonic anhydrase 1	target
Methazolamide	Solute carrier family 22 member 6	transporter
Methazolamide	Carbonic anhydrase 4	target
Methazolamide	Carbonic anhydrase 2	target
Methazolamide	Carbonic anhydrase 7	target
Methazolamide	Carbonic anhydrase 3	target
Delavirdine	Cytochrome P450 3A4	enzyme
Delavirdine	Cytochrome P450 2C9	enzyme
Delavirdine	Cytochrome P450 2D6	enzyme
Delavirdine	Cytochrome P450 3A5	enzyme
Delavirdine	Cytochrome P450 3A7	enzyme
Delavirdine	Cytochrome P450 2C19	enzyme
Delavirdine	Reverse transcriptase/RNaseH	target
Paroxetine	Sodium-dependent serotonin transporter	target
Paroxetine	Sodium-dependent noradrenaline transporter	target
Paroxetine	5-hydroxytryptamine receptor 2A	target
Paroxetine	Cytochrome P450 2D6	enzyme
Paroxetine	Cytochrome P450 2C9	enzyme
Paroxetine	P-glycoprotein 1	transporter
Paroxetine	Cytochrome P450 2B6	enzyme
Paroxetine	Cytochrome P450 1A2	enzyme
Paroxetine	Cytochrome P450 3A4	enzyme
Paroxetine	Alpha-1 adrenergic receptors	target
Paroxetine	Alpha-2 adrenergic receptors	target
Paroxetine	Beta adrenergic receptor	target
Paroxetine	Dopamine D2 receptor	target
Paroxetine	Histamine H1 receptor	target
Paroxetine	Serotonin Receptors	target
Paroxetine	Muscarinic acetylcholine receptor	target
Paroxetine	5-hydroxytryptamine receptor 2B	target
Paroxetine	D(1) dopamine receptor	target
Paroxetine	Cytochrome P450 2C19	enzyme
Lisinopril	Angiotensin-converting enzyme	target
Lisinopril	Solute carrier family 15 member 1	transporter
Lisinopril	Solute carrier family 15 member 2	transporter
Lisinopril	Renin	target
Irinotecan	DNA topoisomerase I, mitochondrial	target
Irinotecan	DNA topoisomerase 1	target
Irinotecan	Cytochrome P450 3A4	enzyme
Irinotecan	Cytochrome P450 3A5	enzyme
Irinotecan	UDP-glucuronosyltransferase 1-1	enzyme
Irinotecan	UDP-glucuronosyltransferase 1-9	enzyme
Irinotecan	Liver carboxylesterase 1	enzyme
Irinotecan	Cytochrome P450 3A7	enzyme
Irinotecan	Cytochrome P450 2B6	enzyme
Irinotecan	Solute carrier family 22 member 3	transporter
Irinotecan	Solute carrier organic anion transporter family member 1B1	transporter
Irinotecan	Multidrug resistance-associated protein 1	transporter
Irinotecan	ATP-binding cassette sub-family G member 2	transporter
Irinotecan	Serum albumin	carrier
Irinotecan	Cocaine esterase	enzyme
Irinotecan	Cholinesterase	enzyme
Irinotecan	P-glycoprotein 1	transporter
Irinotecan	Canalicular multispecific organic anion transporter 1	transporter
Metyrosine	Tyrosine 3-monooxygenase	target
Clavulanic acid	Bacterial beta-lactamase enzymes	target
Clavulanic acid	Sodium/glucose cotransporter 1	transporter
Nalidixic acid	DNA	target
Nalidixic acid	Solute carrier family 22 member 6	transporter
Nalidixic acid	Tryptophan 2,3-dioxygenase	enzyme
Nalidixic acid	Cytochrome P450 1A2	enzyme
Mefenamic acid	Prostaglandin G/H synthase 2	target
Mefenamic acid	Prostaglandin G/H synthase 1	target
Mefenamic acid	Cytochrome P450 2C9	enzyme
Mefenamic acid	Cytochrome P450 2C8	enzyme
Mefenamic acid	Serum albumin	carrier
Mefenamic acid	UDP-glucuronosyltransferase 1-9	enzyme
Mefenamic acid	Cytochrome P450 1A2	enzyme
Mefenamic acid	UDP-glucuronosyltransferase 2B7	enzyme
Marimastat	72 kDa type IV collagenase	target
Marimastat	Matrix metalloproteinase-9	target
Marimastat	Stromelysin-1	target
Marimastat	Interstitial collagenase	target
Marimastat	Stromelysin-2	target
Marimastat	Matrilysin	target
Marimastat	Neutrophil collagenase	target
Marimastat	Stromelysin-3	target
Marimastat	Macrophage metalloelastase	target
Marimastat	Collagenase 3	target
Marimastat	Matrix metalloproteinase-14	target
Marimastat	Matrix metalloproteinase-15	target
Marimastat	Matrix metalloproteinase-16	target
Marimastat	Matrix metalloproteinase-17	target
Marimastat	Matrix metalloproteinase-19	target
Marimastat	Matrix metalloproteinase-20	target
Marimastat	Matrix metalloproteinase-21	target
Marimastat	Matrix metalloproteinase-23	target
Marimastat	Matrix metalloproteinase-24	target
Marimastat	Matrix metalloproteinase-25	target
Marimastat	Matrix metalloproteinase-26	target
Marimastat	Matrix metalloproteinase-27	target
Marimastat	Matrix metalloproteinase-28	target
Naproxen	Prostaglandin G/H synthase 1	target
Naproxen	Prostaglandin G/H synthase 2	target
Naproxen	Serum albumin	carrier
Naproxen	Cytochrome P450 2C9	enzyme
Naproxen	Cytochrome P450 1A2	enzyme
Naproxen	Solute carrier organic anion transporter family member 1A2	transporter
Naproxen	Solute carrier family 22 member 6	transporter
Naproxen	Cytochrome P450 2C8	enzyme
Naproxen	UDP-glucuronosyltransferase 2B7	enzyme
Naproxen	Peptostreptococcal albumin-binding protein	target
Naproxen	Bile salt export pump	transporter
Naproxen	P-glycoprotein 1	transporter
Naproxen	UDP-glucuronosyltransferase 1-3	enzyme
Naproxen	UDP-glucuronosyltransferase 1-6	enzyme
Naproxen	UDP-glucuronosyltransferase 1-7	enzyme
Naproxen	UDP-glucuronosyltransferase 1-8	enzyme
Naproxen	UDP-glucuronosyltransferase 1-9	enzyme
Naproxen	UDP-glucuronosyltransferase 1-10	enzyme
Naproxen	Solute carrier family 22 member 8	transporter
Perindopril	Angiotensin-converting enzyme	target
Perindopril	Solute carrier family 15 member 1	transporter
Perindopril	Solute carrier family 15 member 2	transporter
Perindopril	Cholinesterase	enzyme
Perindopril	Secreted frizzled-related protein 4	target
Pentoxifylline	5'-nucleotidase	target
Pentoxifylline	Adenosine receptor A1	target
Pentoxifylline	Adenosine receptor A2a	target
Pentoxifylline	Cytochrome P450 1A2	enzyme
Pentoxifylline	Phosphodiesterase enzymes	target
Acetazolamide	Carbonic anhydrase 1	target
Acetazolamide	Aquaporin-1	target
Acetazolamide	Carbonic anhydrase 14	target
Acetazolamide	Solute carrier family 22 member 6	transporter
Acetazolamide	Carbonic anhydrase 2	target
Acetazolamide	Carbonic anhydrase 3	target
Acetazolamide	Carbonic anhydrase 4	target
Acetazolamide	Cytochrome P450 3A4	enzyme
Acetazolamide	Carbonic anhydrase 7	target
Acetazolamide	Carbonic anhydrase 12	target
Tadalafil	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Tadalafil	Cytochrome P450 3A4	enzyme
Tadalafil	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	target
Tadalafil	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	target
Donepezil	Acetylcholinesterase	target
Donepezil	5-hydroxytryptamine receptor 2A	target
Donepezil	Cytochrome P450 3A4	enzyme
Donepezil	Cytochrome P450 2D6	enzyme
Donepezil	Cytochrome P450 2C9	enzyme
Donepezil	Cholinesterase	target
Donepezil	Nitric oxide synthase, brain	target
Donepezil	Tumor necrosis factor-inducible gene 6 protein	target
Donepezil	Interleukin-1 beta	target
Donepezil	Nuclear factor NF-kappa-B	target
Donepezil	ATP-binding cassette sub-family G member 2	transporter
Donepezil	NMDA receptor	target
Terbinafine	Squalene monooxygenase	target
Terbinafine	Cytochrome P450 2D6	enzyme
Terbinafine	Cytochrome P450 2C9	enzyme
Terbinafine	Cytochrome P450 1A2	enzyme
Terbinafine	Cytochrome P450 3A4	enzyme
Terbinafine	Cytochrome P450 2C8	enzyme
Terbinafine	Cytochrome P450 2C19	enzyme
Terbinafine	Prostaglandin G/H synthase 1	enzyme
Terbinafine	Serum albumin	carrier
Terbinafine	alpha1-acid glycoprotein	carrier
Terbinafine	ABC multidrug transporter MDR2	transporter
Terbinafine	Squalene monooxygenase	target
Tacrolimus	Peptidyl-prolyl cis-trans isomerase FKBP1A	target
Tacrolimus	Cytochrome P450 3A4	enzyme
Tacrolimus	Cytochrome P450 3A5	enzyme
Tacrolimus	P-glycoprotein 1	transporter
Tacrolimus	ATP-binding cassette sub-family A member 5	transporter
Tacrolimus	Serum albumin	carrier
Tacrolimus	Alpha-1-acid glycoprotein 1	carrier
Tacrolimus	Solute carrier organic anion transporter family member 1B1	transporter
Dorzolamide	Carbonic anhydrase 2	target
Dorzolamide	Carbonic anhydrase 1	target
Dorzolamide	Carbonic anhydrase 4	target
Dorzolamide	Cytochrome P450 2C9	enzyme
Dorzolamide	Carbonic anhydrase 3	target
Dorzolamide	Cytochrome P450 2B1	enzyme
Dorzolamide	Cytochrome P450 2E1	enzyme
Dorzolamide	Cytochrome P450 3A2	enzyme
Suprofen	Prostaglandin G/H synthase 1	target
Suprofen	Prostaglandin G/H synthase 2	target
Suprofen	Cytochrome P450 2C9	enzyme
Suprofen	UDP-glucuronosyltransferase 1-1	enzyme
Suprofen	Solute carrier family 22 member 12	transporter
Suprofen	UDP-glucuronosyltransferase 2B7	enzyme
Suprofen	Serum albumin	carrier
Emtricitabine	Reverse transcriptase/RNaseH	target
Emtricitabine	Deoxycytidine kinase	enzyme
Emtricitabine	Serum albumin	carrier
Emtricitabine	Multidrug and toxin extrusion protein 1	transporter
Quinapril	Angiotensin-converting enzyme	target
Quinapril	Solute carrier family 15 member 1	transporter
Quinapril	Solute carrier family 15 member 2	transporter
Quinapril	Solute carrier family 22 member 8	transporter
Quinapril	Liver carboxylesterase 1	enzyme
Quinapril	Serum albumin	carrier
Omapatrilat	Neprilysin	target
Omapatrilat	Angiotensin-converting enzyme	target
Etacrynic acid	Solute carrier family 12 member 1	target
Etacrynic acid	Sodium/potassium-transporting ATPase subunit alpha-1	target
Etacrynic acid	Glutathione S-transferase A2	enzyme
Etacrynic acid	Serum albumin	carrier
Etacrynic acid	Solute carrier family 22 member 6	transporter
Etacrynic acid	Lymphoid enhancer-binding factor 1	target
Etacrynic acid	Glutathione S-transferase P	target
Azacitidine	DNA (cytosine-5)-methyltransferase 1	target
Azacitidine	Cytidine deaminase	enzyme
Azacitidine	DNA	target
Azacitidine	RNA	target
Demecarium	Acetylcholinesterase	target
Demecarium	Cholinesterase	target
Azelastine	Histamine H1 receptor	target
Azelastine	Cytochrome P450 1A2	enzyme
Azelastine	Cytochrome P450 2D6	enzyme
Azelastine	Cytochrome P450 3A4	enzyme
Azelastine	Cytochrome P450 2C19	enzyme
Azelastine	Cytochrome P450 1A1	enzyme
Azelastine	Cytochrome P450 3A5	enzyme
Azelastine	Cytochrome P450 2C9	enzyme
Azelastine	Cytochrome P450 2C8	enzyme
Azelastine	P-glycoprotein 1	transporter
Azelastine	Cytochrome P450 2A6	enzyme
Azelastine	Cytochrome P450 2E1	enzyme
Azelastine	Histamine H2 receptor	target
Azelastine	Phospholipase A2	target
Azelastine	Leukotriene C4 synthase	target
Azelastine	Cytochrome P450 2B6	enzyme
Lomefloxacin	DNA gyrase subunit A	target
Lomefloxacin	DNA topoisomerase 4 subunit A	target
Lomefloxacin	DNA topoisomerase 2-alpha	target
Lomefloxacin	Cytochrome P450 1A2	enzyme
Lomefloxacin	Solute carrier family 22 member 5	transporter
Lomefloxacin	Canalicular multispecific organic anion transporter 1	transporter
Exemestane	Cytochrome P450 19A1	target
Exemestane	Cytochrome P450 3A4	enzyme
Exemestane	Cytochrome P450 19A1	enzyme
Neomycin	30S ribosomal protein S12	target
Neomycin	16S ribosomal RNA	target
Neomycin	Extracellular calcium-sensing receptor	target
Doxorubicin	DNA topoisomerase 2-alpha	target
Doxorubicin	DNA	target
Doxorubicin	Cytochrome P450 3A4	enzyme
Doxorubicin	Cytochrome P450 2D6	enzyme
Doxorubicin	Cytochrome P450 2B6	enzyme
Doxorubicin	P-glycoprotein 1	transporter
Doxorubicin	Canalicular multispecific organic anion transporter 2	transporter
Doxorubicin	Multidrug resistance-associated protein 6	transporter
Doxorubicin	Multidrug resistance-associated protein 1	transporter
Doxorubicin	Multidrug resistance-associated protein 7	transporter
Doxorubicin	ATP-binding cassette sub-family G member 2	transporter
Doxorubicin	Bile salt export pump	transporter
Doxorubicin	Solute carrier family 22 member 16	transporter
Doxorubicin	ATP-binding cassette sub-family B member 8, mitochondrial	transporter
Doxorubicin	Cytochrome P450 1B1	enzyme
Doxorubicin	Carbonyl reductase [NADPH] 1	enzyme
Doxorubicin	Carbonyl reductase [NADPH] 3	enzyme
Doxorubicin	Alcohol dehydrogenase [NADP(+)]	enzyme
Doxorubicin	Aldo-keto reductase family 1 member C3	enzyme
Doxorubicin	NAD(P)H dehydrogenase [quinone] 1	enzyme
Doxorubicin	Xanthine dehydrogenase/oxidase	enzyme
Doxorubicin	Nitric oxide synthase, endothelial	enzyme
Doxorubicin	Nitric oxide synthase, inducible	enzyme
Doxorubicin	Nitric oxide synthase, brain	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	enzyme
Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	enzyme
Doxorubicin	NADPH--cytochrome P450 reductase	enzyme
Doxorubicin	RalA-binding protein 1	transporter
Doxorubicin	Canalicular multispecific organic anion transporter 1	transporter
Doxorubicin	Serum albumin	carrier
Doxorubicin	Nucleolar and coiled-body phosphoprotein 1	target
Doxorubicin	DNA topoisomerase 1	target
Doxorubicin	DNA topoisomerase 2-beta	target
Doxorubicin	Aldose reductase	enzyme
Doxorubicin	Aldo-keto reductase family 1 member B10	enzyme
Doxorubicin	Aldo-keto reductase family 1 member C4	enzyme
Hydroxyurea	Ribonucleoside-diphosphate reductase large subunit	target
Hydroxyurea	Solute carrier organic anion transporter family member 1A2	transporter
Hydroxyurea	Solute carrier organic anion transporter family member 1B1	transporter
Hydroxyurea	Solute carrier organic anion transporter family member 1B3	transporter
Hydroxyurea	Urea transporter 2	transporter
Hydroxyurea	Urea transporter 1	transporter
Hydroxyurea	Solute carrier family 22 member 4	transporter
Hydroxyurea	Solute carrier family 22 member 5	transporter
Hydroxyurea	Serum albumin	carrier
Hydroxyurea	Urease subunit alpha	enzyme
Letrozole	Cytochrome P450 19A1	target
Letrozole	Cytochrome P450 3A4	enzyme
Letrozole	Cytochrome P450 2A6	enzyme
Letrozole	Cytochrome P450 19A1	enzyme
Letrozole	Cytochrome P450 2C19	enzyme
Letrozole	UDP-glucuronosyltransferase 2B7	enzyme
Letrozole	Serum albumin	carrier
Letrozole	P-glycoprotein 1	transporter
Edrophonium	Acetylcholinesterase	target
Edrophonium	Cholinesterase	target
Metyrapone	Camphor 5-monooxygenase	target
Metyrapone	Cytochrome P450 11B2, mitochondrial	enzyme
Metyrapone	Cytochrome P450 2A6	enzyme
Metyrapone	Cytochrome P450 3A4	enzyme
Metyrapone	Canalicular multispecific organic anion transporter 2	transporter
Metyrapone	Cytochrome P450 11B1, mitochondrial	target
Metyrapone	Cytochrome P450 11B1, mitochondrial	enzyme
Metyrapone	Cytochrome P450 2E1	enzyme
Ketoconazole	Cytochrome P450 3A4	enzyme
Ketoconazole	Cytochrome P450 2C9	enzyme
Ketoconazole	Cytochrome P450 2C19	enzyme
Ketoconazole	Cytochrome P450 3A5	enzyme
Ketoconazole	Cytochrome P450 1A2	enzyme
Ketoconazole	Cytochrome P450 2C8	enzyme
Ketoconazole	Cytochrome P450 1A1	enzyme
Ketoconazole	Cytochrome P450 2D6	enzyme
Ketoconazole	Bile salt export pump	transporter
Ketoconazole	P-glycoprotein 1	transporter
Ketoconazole	Cytochrome P450 11B1, mitochondrial	enzyme
Ketoconazole	Cytochrome P450 1B1	enzyme
Ketoconazole	Cytochrome P450 2A6	enzyme
Ketoconazole	Cytochrome P450 2B6	enzyme
Ketoconazole	Lanosterol 14-alpha demethylase	target
Ketoconazole	Androgen receptor	target
Ketoconazole	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Ketoconazole	Steroid 21-hydroxylase	target
Ketoconazole	Potassium voltage-gated channel subfamily H member 2	target
Ketoconazole	Nuclear receptor subfamily 1 group I member 2	target
Ketoconazole	Nuclear receptor subfamily 1 group I member 3	target
Ketoconazole	UDP-glucuronosyltransferase 1-1	enzyme
Ketoconazole	UDP-glucuronosyltransferase 2B7	enzyme
Ketoconazole	Solute carrier organic anion transporter family member 1B1	transporter
Ketoconazole	Cytochrome P450 4F12	enzyme
Ketoconazole	Leukotriene-B(4) omega-hydroxylase 1	enzyme
Ketoconazole	Serum albumin	carrier
Ketoconazole	Sex hormone-binding globulin	carrier
Ketoconazole	Cytochrome P450 19A1	enzyme
Ketoconazole	UDP-glucuronosyltransferase 1-7	enzyme
Topotecan	DNA topoisomerase I, mitochondrial	target
Topotecan	DNA topoisomerase 1	target
Topotecan	ATP-binding cassette sub-family G member 2	transporter
Topotecan	P-glycoprotein 1	transporter
Topotecan	DNA	target
Topotecan	Multidrug and toxin extrusion protein 1	transporter
Topotecan	Multidrug and toxin extrusion protein 2	transporter
Gatifloxacin	Serum albumin	carrier
Gatifloxacin	DNA gyrase subunit A	target
Gatifloxacin	DNA gyrase subunit B	target
Gatifloxacin	DNA topoisomerase 4 subunit A	target
Gatifloxacin	DNA topoisomerase 4 subunit B	target
Gatifloxacin	Cytochrome P450 1A2	enzyme
Ibuprofen	Prostaglandin G/H synthase 1	target
Ibuprofen	Prostaglandin G/H synthase 2	target
Ibuprofen	Cytochrome P450 2C9	enzyme
Ibuprofen	Serum albumin	carrier
Ibuprofen	Multidrug resistance-associated protein 4	transporter
Ibuprofen	Multidrug resistance-associated protein 1	transporter
Ibuprofen	Solute carrier organic anion transporter family member 1A2	transporter
Ibuprofen	Solute carrier family 22 member 6	transporter
Ibuprofen	Solute carrier family 22 member 8	transporter
Ibuprofen	Solute carrier family 22 member 11	transporter
Ibuprofen	Solute carrier organic anion transporter family member 2B1	transporter
Ibuprofen	P-glycoprotein 1	transporter
Ibuprofen	UDP-glucuronosyltransferase 1-3	enzyme
Ibuprofen	UDP-glucuronosyltransferase 1-9	enzyme
Ibuprofen	UDP-glucuronosyltransferase 2B4	enzyme
Ibuprofen	UDP-glucuronosyltransferase 2B7	enzyme
Ibuprofen	Cytochrome P450 2C8	enzyme
Ibuprofen	Cytochrome P450 2C19	enzyme
Ibuprofen	Apoptosis regulator Bcl-2	target
Ibuprofen	Thrombomodulin	target
Ibuprofen	Fatty acid-binding protein, intestinal	target
Ibuprofen	Peroxisome proliferator-activated receptor gamma	target
Ibuprofen	Cystic fibrosis transmembrane conductance regulator	target
Ibuprofen	Peroxisome proliferator-activated receptor alpha	target
Ibuprofen	Platelet glycoprotein Ib alpha chain	target
Ibuprofen	Protein S100-A7	target
Ibuprofen	Alpha-methylacyl-CoA racemase	enzyme
Ibuprofen	Cytochrome P450 3A4	enzyme
Norfloxacin	DNA gyrase subunit A	target
Norfloxacin	DNA topoisomerase 4 subunit A	target
Norfloxacin	DNA topoisomerase 2-alpha	target
Norfloxacin	Cytochrome P450 1A2	enzyme
Norfloxacin	Cytochrome P450 3A4	enzyme
Norfloxacin	Solute carrier family 22 member 5	transporter
Norfloxacin	Solute carrier family 22 member 6	transporter
Norfloxacin	Cytochrome P450 1A1	enzyme
Norfloxacin	Cytochrome P450 3A7	enzyme
Norfloxacin	DNA gyrase subunit A	target
Norfloxacin	DNA topoisomerase 2	target
Norfloxacin	DNA topoisomerase 4 subunit A	target
Atazanavir	Human immunodeficiency virus type 1 protease	target
Atazanavir	Cytochrome P450 3A4	enzyme
Atazanavir	Cytochrome P450 2C9	enzyme
Atazanavir	P-glycoprotein 1	transporter
Atazanavir	Multidrug resistance-associated protein 1	transporter
Atazanavir	Serum albumin	carrier
Atazanavir	UDP-glucuronosyltransferase 1-1	enzyme
Atazanavir	Solute carrier organic anion transporter family member 1B1	transporter
Atazanavir	Solute carrier organic anion transporter family member 1B3	transporter
Atazanavir	Cytochrome P450 2C8	enzyme
Atazanavir	Bile salt export pump	transporter
Atazanavir	alpha1-acid glycoprotein	carrier
Atazanavir	Cytochrome P450 1A2	enzyme
Atazanavir	Solute carrier organic anion transporter family member 2B1	transporter
Atazanavir	Cytochrome P450 3A5	enzyme
Atazanavir	Cytochrome P450 3A7	enzyme
Atorvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Atorvastatin	Cytochrome P450 3A4	enzyme
Atorvastatin	Dipeptidyl peptidase 4	target
Atorvastatin	Cytochrome P450 2D6	enzyme
Atorvastatin	Cytochrome P450 2C9	enzyme
Atorvastatin	Cytochrome P450 2C19	enzyme
Atorvastatin	Cytochrome P450 3A5	enzyme
Atorvastatin	Cytochrome P450 3A7	enzyme
Atorvastatin	P-glycoprotein 1	transporter
Atorvastatin	Solute carrier organic anion transporter family member 1A2	transporter
Atorvastatin	Solute carrier organic anion transporter family member 1B1	transporter
Atorvastatin	Multidrug resistance-associated protein 4	transporter
Atorvastatin	Multidrug resistance-associated protein 5	transporter
Atorvastatin	Multidrug resistance-associated protein 1	transporter
Atorvastatin	Cytochrome P450 2B6	enzyme
Atorvastatin	Cytochrome P450 2C8	enzyme
Atorvastatin	Aryl hydrocarbon receptor	target
Atorvastatin	Solute carrier organic anion transporter family member 2B1	transporter
Atorvastatin	Solute carrier organic anion transporter family member 1B3	transporter
Atorvastatin	UDP-glucuronosyltransferase 1-1	enzyme
Atorvastatin	UDP-glucuronosyltransferase 1-3	enzyme
Atorvastatin	Canalicular multispecific organic anion transporter 1	transporter
Atorvastatin	Bile salt export pump	transporter
Atorvastatin	Serum albumin	carrier
Atorvastatin	Histone deacetylase 2	target
Atorvastatin	Nuclear receptor subfamily 1 group I member 3	target
Deslanoside	Sodium/potassium-transporting ATPase subunit alpha-1	target
Orlistat	Pancreatic triacylglycerol lipase	target
Orlistat	Fatty acid synthase	target
Orlistat	Gastric triacylglycerol lipase	target
Orlistat	Cytochrome P450 3A4	enzyme
Orlistat	Cytosolic phospholipase A2	enzyme
Orlistat	Serum albumin	carrier
Orlistat	Fatty acid synthase	enzyme
Quinacrine	DNA	target
Quinacrine	85/88 kDa calcium-independent phospholipase A2	target
Quinacrine	Cytosolic phospholipase A2	target
Quinacrine	Inactive phospholipase C-like protein 1	target
Quinacrine	Histamine N-methyltransferase	enzyme
Quinacrine	Solute carrier family 22 member 2	transporter
Quinacrine	P-glycoprotein 1	transporter
Quinacrine	Cytochrome P450 3A4	enzyme
Quinacrine	Cytochrome P450 3A5	enzyme
Trilostane	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	target
Trilostane	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2	target
Trilostane	Estrogen receptor beta	target
Trilostane	Estrogen receptor alpha	target
Miconazole	Cytochrome P450 2C9	enzyme
Miconazole	Cytochrome P450 2D6	enzyme
Miconazole	Cytochrome P450 3A4	enzyme
Miconazole	P-glycoprotein 1	transporter
Miconazole	Cytochrome P450 51	target
Miconazole	Nitric oxide synthase, endothelial	target
Miconazole	Nitric oxide synthase, inducible	target
Miconazole	Cytochrome P450 11B1, mitochondrial	enzyme
Miconazole	Cytochrome P450 2A6	enzyme
Miconazole	Cytochrome P450 2B6	enzyme
Miconazole	Cytochrome P450 2C19	enzyme
Miconazole	Cytochrome P450 2E1	enzyme
Miconazole	Nuclear receptor subfamily 1 group I member 2	target
Miconazole	Lanosterol 14-alpha demethylase	enzyme
Miconazole	Cytochrome P450 19A1	enzyme
Miconazole	Calcium-activated potassium channel	target
Miconazole	Voltage-gated Potassium Channels	target
Miconazole	Inward rectifier potassium channel	target
Miconazole	Voltage gated L-type calcium channel	target
Miconazole	Serum albumin	carrier
Miconazole	Cytochrome P450 2C8	enzyme
Atovaquone	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Atovaquone	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Atovaquone	Cytochrome b	target
Atovaquone	Cytochrome P450 2C9	enzyme
Atovaquone	Cytochrome P450 3A4	enzyme
Atovaquone	P-glycoprotein 1	transporter
Amiodarone	Beta adrenergic receptor	target
Amiodarone	HERG human cardiac K+ channel	target
Amiodarone	Cytochrome P450 2C8	enzyme
Amiodarone	Cytochrome P450 2C9	enzyme
Amiodarone	Cytochrome P450 2D6	enzyme
Amiodarone	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Amiodarone	Voltage gated L-type calcium channel	target
Amiodarone	Cytochrome P450 3A4	enzyme
Amiodarone	Cytochrome P450 1A2	enzyme
Amiodarone	Cytochrome P450 1A1	enzyme
Amiodarone	P-glycoprotein 1	transporter
Amiodarone	Cytochrome P450 2C19	enzyme
Amiodarone	Cytochrome P450 2A6	enzyme
Amiodarone	Thyroid hormone receptor	target
Amiodarone	Peroxisome proliferator-activated receptor gamma	target
Amiodarone	Bile salt export pump	transporter
Amiodarone	Solute carrier family 22 member 2	transporter
Amiodarone	Cytochrome P450 2J2	enzyme
Amiodarone	Peroxisome proliferator-activated receptor alpha	target
Amiodarone	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	target
Amiodarone	Serum albumin	carrier
Dutasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 1	target
Dutasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 2	target
Dutasteride	Sodium-dependent dopamine transporter	transporter
Dutasteride	Synaptic vesicular amine transporter	transporter
Dutasteride	Serum albumin	carrier
Dutasteride	Alpha-1-acid glycoprotein 1	carrier
Dutasteride	Cytochrome P450 3A5	enzyme
Econazole	Cytochrome P450 19A1	enzyme
Econazole	Cytochrome P450 2E1	enzyme
Econazole	Cytochrome P450 3A4	enzyme
Econazole	Cytochrome P450 51	target
Econazole	Nuclear receptor subfamily 1 group I member 2	target
Levofloxacin	DNA gyrase subunit A	target
Levofloxacin	DNA topoisomerase 4 subunit A	target
Levofloxacin	Solute carrier family 22 member 2	transporter
Levofloxacin	P-glycoprotein 1	transporter
Levofloxacin	Solute carrier family 22 member 4	transporter
Levofloxacin	Multidrug and toxin extrusion protein 1	transporter
Levofloxacin	Multidrug and toxin extrusion protein 2	transporter
Levofloxacin	Cytochrome P450 2C9	enzyme
Levofloxacin	Serum albumin	carrier
Levofloxacin	Solute carrier organic anion transporter family member 4C1	transporter
Levofloxacin	Solute carrier family 22 member 1	transporter
Levofloxacin	Solute carrier organic anion transporter family member 1A2	transporter
Gemifloxacin	DNA gyrase subunit A	target
Gemifloxacin	DNA topoisomerase 4 subunit A	target
Gemifloxacin	Cytochrome P450 1A2	enzyme
Bupropion	Sodium-dependent dopamine transporter	target
Bupropion	Sodium-dependent noradrenaline transporter	target
Bupropion	Cytochrome P450 2B6	enzyme
Bupropion	Cytochrome P450 2D6	enzyme
Bupropion	Alpha-1-acid glycoprotein 1	carrier
Bupropion	Neuronal acetylcholine receptor subunit alpha-3	target
Bupropion	Cytochrome P450 2C9	enzyme
Bupropion	Cytochrome P450 2E1	enzyme
Bupropion	Solute carrier family 22 member 2	transporter
Bupropion	5-hydroxytryptamine receptor 3A	target
Trimetrexate	Dihydrofolate reductase	target
Trimetrexate	Folate transporter 1	transporter
Ofloxacin	DNA gyrase subunit A	target
Ofloxacin	DNA topoisomerase 4 subunit A	target
Ofloxacin	DNA topoisomerase 2-alpha	target
Ofloxacin	Cytochrome P450 1A2	enzyme
Ofloxacin	Solute carrier family 22 member 5	transporter
Ofloxacin	Multidrug resistance-associated protein 1	transporter
Ofloxacin	Solute carrier family 22 member 6	transporter
Ofloxacin	Canalicular multispecific organic anion transporter 1	transporter
Ofloxacin	Solute carrier family 22 member 4	transporter
Ofloxacin	Bile salt export pump	transporter
Itraconazole	Lanosterol 14-alpha demethylase	target
Itraconazole	Lanosterol 14-alpha demethylase	target
Itraconazole	Cytochrome P450 3A4	enzyme
Itraconazole	Cytochrome P450 3A5	enzyme
Itraconazole	Cytochrome P450 3A7	enzyme
Itraconazole	Cytochrome P450 2B6	enzyme
Itraconazole	P-glycoprotein 1	transporter
Itraconazole	Cytochrome P450 1A1	enzyme
Itraconazole	Cytochrome P450 2E1	enzyme
Itraconazole	Solute carrier organic anion transporter family member 2B1	transporter
Itraconazole	Cytochrome P450 3A Subfamily	enzyme
Kanamycin	30S ribosomal protein S12	target
Kanamycin	16S ribosomal RNA	target
Kanamycin	Aminoglycoside 2'-N-acetyltransferase	enzyme
Kanamycin	Kanamycin nucleotidyltransferase	enzyme
Kanamycin	Aminoglycoside 3'-phosphotransferase	enzyme
Orphenadrine	Glutamate receptor ionotropic, NMDA 1	target
Orphenadrine	Glutamate receptor ionotropic, NMDA 2D	target
Orphenadrine	Glutamate receptor ionotropic, NMDA 3B	target
Orphenadrine	Glutamate receptor ionotropic, NMDA 3A	target
Orphenadrine	Histamine H1 receptor	target
Orphenadrine	Cytochrome P450 2B6	enzyme
Orphenadrine	Cytochrome P450 2E1	enzyme
Orphenadrine	Cytochrome P450 3A4	enzyme
Orphenadrine	Sodium-dependent noradrenaline transporter	target
Orphenadrine	Sodium channel protein type 10 subunit alpha	target
Orphenadrine	Cytochrome P450 1A2	enzyme
Orphenadrine	Cytochrome P450 2D6	enzyme
Orphenadrine	Serum albumin	carrier
Clindamycin	Cytochrome P450 3A4	enzyme
Clindamycin	Cytochrome P450 3A5	enzyme
Clindamycin	Alpha-1-acid glycoprotein 1	carrier
Clindamycin	P-glycoprotein 1	transporter
Clindamycin	50S ribosomal protein L1	target
Brinzolamide	Carbonic anhydrase 1	target
Brinzolamide	Carbonic anhydrase 2	target
Brinzolamide	Cytochrome P450 3A4	enzyme
Brinzolamide	Carbonic anhydrase 5A, mitochondrial	target
Brinzolamide	Carbonic anhydrase 4	target
Brinzolamide	Carbonic anhydrase 3	target
Brinzolamide	Cytochrome P450 2A6	enzyme
Brinzolamide	Cytochrome P450 2B6	enzyme
Brinzolamide	Cytochrome P450 2C8	enzyme
Brinzolamide	Cytochrome P450 2C9	enzyme
Captopril	Angiotensin-converting enzyme	target
Captopril	Serum albumin	carrier
Captopril	72 kDa type IV collagenase	target
Captopril	Matrix metalloproteinase-9	target
Captopril	P-glycoprotein 1	transporter
Captopril	Solute carrier family 15 member 1	transporter
Captopril	Solute carrier family 22 member 6	transporter
Captopril	Leukotriene A-4 hydrolase	target
Captopril	B1 bradykinin receptor	target
Ridogrel	Thromboxane-A synthase	target
Ridogrel	Thromboxane A2 receptor	target
Clarithromycin	50S ribosomal protein L10	target
Clarithromycin	Cytochrome P450 3A4	enzyme
Clarithromycin	Cytochrome P450 3A5	enzyme
Clarithromycin	P-glycoprotein 1	transporter
Clarithromycin	Solute carrier family 22 member 7	transporter
Clarithromycin	Potassium voltage-gated channel subfamily H member 2	target
Clarithromycin	Solute carrier organic anion transporter family member 1B1	target
Clarithromycin	Solute carrier organic anion transporter family member 1B3	target
Clarithromycin	Bile salt export pump	transporter
Clarithromycin	Solute carrier organic anion transporter family member 1B1	transporter
Clarithromycin	Solute carrier organic anion transporter family member 1B3	transporter
Finasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 1	target
Finasteride	Cytochrome P450 3A4	enzyme
Finasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 2	target
Finasteride	3-oxo-5-beta-steroid 4-dehydrogenase	target
Finasteride	Cytochrome P450 3A5	enzyme
Finasteride	Cytochrome P450 3A7	enzyme
Finasteride	Solute carrier family 12 member 5	transporter
Anastrozole	Cytochrome P450 19A1	target
Anastrozole	P-glycoprotein 1	transporter
Anastrozole	Cytochrome P450 3A4	enzyme
Anastrozole	Cytochrome P450 3A5	enzyme
Anastrozole	Cytochrome P450 2C8	enzyme
Anastrozole	UDP-glucuronosyltransferase 1-4	enzyme
Anastrozole	UDP-glucuronosyltransferase 1-3	enzyme
Anastrozole	UDP-glucuronosyltransferase 2B7	enzyme
Anastrozole	Cytochrome P450 1A2	enzyme
Anastrozole	Cytochrome P450 2C9	enzyme
Saquinavir	Human immunodeficiency virus type 1 protease	target
Saquinavir	Cytochrome P450 3A4	enzyme
Saquinavir	Cytochrome P450 3A5	enzyme
Saquinavir	Alpha-1-acid glycoprotein 1	carrier
Saquinavir	Serum albumin	carrier
Saquinavir	Cytochrome P450 3A7	enzyme
Saquinavir	P-glycoprotein 1	transporter
Saquinavir	Solute carrier family 22 member 1	transporter
Saquinavir	Solute carrier organic anion transporter family member 1A2	transporter
Saquinavir	ATP-binding cassette sub-family G member 2	transporter
Saquinavir	Solute carrier organic anion transporter family member 1B1	transporter
Saquinavir	Multidrug resistance-associated protein 1	transporter
Saquinavir	Canalicular multispecific organic anion transporter 1	transporter
Saquinavir	Cytochrome P450 2C8	enzyme
Saquinavir	Cytochrome P450 2D6	enzyme
Saquinavir	Solute carrier organic anion transporter family member 2B1	transporter
Saquinavir	Bile salt export pump	transporter
Gemfibrozil	Peroxisome proliferator-activated receptor alpha	target
Gemfibrozil	Cytochrome P450 2C9	enzyme
Gemfibrozil	Cytochrome P450 2C8	enzyme
Gemfibrozil	Cytochrome P450 1A2	enzyme
Gemfibrozil	Cytochrome P450 2C19	enzyme
Gemfibrozil	UDP-glucuronosyltransferase 1-1	enzyme
Gemfibrozil	Cytochrome P450 3A4	enzyme
Gemfibrozil	UDP-glucuronosyltransferase 1-3	enzyme
Gemfibrozil	Solute carrier organic anion transporter family member 1B1	target
Gemfibrozil	UDP-glucuronosyltransferase 2B7	enzyme
Gemfibrozil	UDP-glucuronosyltransferase 1-9	enzyme
Gemfibrozil	UDP-glucuronosyltransferase 2B4	enzyme
Gemfibrozil	UDP-glucuronosyltransferase 2B17	enzyme
Gemfibrozil	Serum albumin	carrier
Gemfibrozil	Solute carrier family 22 member 8	target
Gemfibrozil	Solute carrier organic anion transporter family member 2B1	target
Gemfibrozil	Solute carrier organic anion transporter family member 1B3	target
Dasatinib	Tyrosine-protein kinase ABL1	target
Dasatinib	Tyrosine-protein kinase ABL2	target
Dasatinib	Proto-oncogene tyrosine-protein kinase Src	target
Dasatinib	Tyrosine-protein kinase Fyn	target
Dasatinib	Tyrosine-protein kinase Lck	target
Dasatinib	Tyrosine-protein kinase Yes	target
Dasatinib	Mast/stem cell growth factor receptor Kit	target
Dasatinib	Platelet-derived growth factor receptor beta	target
Dasatinib	Ephrin type-A receptor 2	target
Dasatinib	Signal transducer and activator of transcription 5B	target
Dasatinib	Cytochrome P450 3A4	enzyme
Dasatinib	P-glycoprotein 1	transporter
Dasatinib	ATP-binding cassette sub-family G member 2	transporter
Dasatinib	Cytochrome P450 1A1	enzyme
Dasatinib	Cytochrome P450 1A2	enzyme
Dasatinib	Cytochrome P450 1B1	enzyme
Dasatinib	Cytochrome P450 3A5	enzyme
Dasatinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Dasatinib	Tyrosine-protein kinase BTK	target
Dasatinib	Nuclear receptor subfamily 4 group A member 3	target
Dasatinib	Breakpoint cluster region protein	target
Dasatinib	Tyrosine-protein kinase CSK	target
Dasatinib	Ephrin type-A receptor 5	target
Dasatinib	Ephrin type-B receptor 4	target
Dasatinib	Tyrosine-protein kinase Fgr	target
Dasatinib	Tyrosine-protein kinase FRK	target
Dasatinib	Heat shock cognate 71 kDa protein	target
Dasatinib	Tyrosine-protein kinase Lyn	target
Dasatinib	Mitogen-activated protein kinase kinase kinase MLT	target
Dasatinib	Mitogen-activated protein kinase 14	target
Dasatinib	Amidophosphoribosyltransferase	target
Lapatinib	Epidermal growth factor receptor	target
Lapatinib	Receptor tyrosine-protein kinase erbB-2	target
Lapatinib	Cytochrome P450 3A4	enzyme
Lapatinib	Cytochrome P450 2C8	enzyme
Lapatinib	P-glycoprotein 1	transporter
Lapatinib	Antigen peptide transporter 1	transporter
Lapatinib	Cytochrome P450 3A5	enzyme
Lapatinib	Cytochrome P450 2C19	enzyme
Sitagliptin	Dipeptidyl peptidase 4	target
Sitagliptin	Cytochrome P450 3A4	enzyme
Sitagliptin	Cytochrome P450 2C8	enzyme
Sitagliptin	P-glycoprotein 1	transporter
Sitagliptin	Solute carrier family 22 member 8	transporter
Decitabine	DNA	target
Decitabine	DNA (cytosine-5)-methyltransferase 1	target
Decitabine	Deoxycytidine kinase	enzyme
Decitabine	UMP-CMP kinase	enzyme
Decitabine	Nucleoside diphosphokinase	enzyme
Decitabine	Cytidine deaminase	enzyme
Decitabine	DNA (cytosine-5)-methyltransferase 3A	target
Decitabine	DNA (cytosine-5)-methyltransferase 3B	target
Decitabine	Sodium/nucleoside cotransporter 1	transporter
Decitabine	Histone deacetylase	target
Posaconazole	Cytochrome P450 3A4	enzyme
Posaconazole	P-glycoprotein 1	transporter
Posaconazole	Cytochrome P450 51	target
Darunavir	Human immunodeficiency virus type 1 protease	target
Darunavir	Cytochrome P450 3A4	enzyme
Darunavir	Solute carrier organic anion transporter family member 1B1	transporter
Darunavir	P-glycoprotein 1	transporter
Darunavir	Serum albumin	carrier
Darunavir	Alpha-1-acid glycoprotein 1	carrier
Darunavir	Cytochrome P450 2D6	enzyme
Fosamprenavir	Human immunodeficiency virus type 1 protease	target
Fosamprenavir	Cytochrome P450 3A4	enzyme
Cilazapril	Angiotensin-converting enzyme	target
Cilazapril	P-glycoprotein 1	transporter
Cilazapril	Solute carrier family 15 member 1	transporter
Cilazapril	Solute carrier family 15 member 2	transporter
Spirapril	Angiotensin-converting enzyme	target
Spirapril	Solute carrier family 15 member 1	transporter
Spirapril	Solute carrier family 15 member 2	transporter
Digitoxin	Sodium/potassium-transporting ATPase subunit alpha-1	target
Digitoxin	Serum albumin	carrier
Digitoxin	Cholesterol side-chain cleavage enzyme, mitochondrial	enzyme
Digitoxin	Cytochrome P450 3A4	enzyme
Digitoxin	Solute carrier organic anion transporter family member 1A2	transporter
Digitoxin	Solute carrier organic anion transporter family member 4C1	transporter
Digitoxin	P-glycoprotein 1	transporter
Cilastatin	Dipeptidase 1	target
Cilastatin	Solute carrier family 22 member 6	transporter
Cilastatin	Solute carrier family 22 member 8	transporter
Lopinavir	Human immunodeficiency virus type 1 protease	target
Lopinavir	Cytochrome P450 3A4	enzyme
Lopinavir	Cytochrome P450 2D6	enzyme
Lopinavir	Cytochrome P450 2C19	enzyme
Lopinavir	P-glycoprotein 1	transporter
Lopinavir	Cytochrome P450 2B6	enzyme
Lopinavir	Cytochrome P450 2C9	enzyme
Lopinavir	Cytochrome P450 3A Subfamily	enzyme
Lopinavir	Solute carrier organic anion transporter family member 1B1	transporter
Lopinavir	Solute carrier organic anion transporter family member 1B3	transporter
Lopinavir	Bile salt export pump	transporter
Lopinavir	Cytochrome P450 1A2	enzyme
Lopinavir	Alpha-1-acid glycoprotein 1	carrier
Lopinavir	Serum albumin	carrier
Tazobactam	Beta-lactamase TEM	target
Tazobactam	Solute carrier family 22 member 6	transporter
Tazobactam	Solute carrier family 22 member 8	transporter
Tazobactam	Beta-lactamase Ohio-1	target
Tazobactam	Beta-lactamase SHV-1	target
Hydroxychloroquine	DNA	target
Hydroxychloroquine	Toll-like receptor 7	target
Hydroxychloroquine	Toll-like receptor 9	target
Hydroxychloroquine	Cytochrome P450 2D6	enzyme
Hydroxychloroquine	P-glycoprotein 1	transporter
Hydroxychloroquine	Serum albumin	carrier
Hydroxychloroquine	alpha1-acid glycoprotein	carrier
Hydroxychloroquine	Cytochrome P450 3A4	enzyme
Hydroxychloroquine	Solute carrier organic anion transporter family member 1A2	transporter
Hydroxychloroquine	Angiotensin-converting enzyme 2	target
Hydroxychloroquine	Cytochrome P450 2C8	enzyme
Lincomycin	23S ribosomal RNA	target
Lincomycin	Alpha-1-acid glycoprotein 1	carrier
Chymostatin	Peptide amidase	target
N,N-dimethylarginine	Nitric oxide synthase, inducible	target
N,N-dimethylarginine	Nitric oxide synthase, endothelial	target
Castanospermine	Glucan 1,3-beta-glucosidase	target
Staurosporine	Tyrosine-protein kinase Lck	target
Staurosporine	Serine/threonine-protein kinase pim-1	target
Staurosporine	Tyrosine-protein kinase ITK/TSK	target
Staurosporine	Tyrosine-protein kinase SYK	target
Staurosporine	MAP kinase-activated protein kinase 2	target
Staurosporine	Glycogen synthase kinase-3 beta	target
Staurosporine	Tyrosine-protein kinase CSK	target
Staurosporine	Cyclin-dependent kinase 2	target
Staurosporine	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
Staurosporine	3-phosphoinositide-dependent protein kinase 1	target
Staurosporine	Protein kinase C theta type	target
Staurosporine	Tyrosine-protein kinase ZAP-70	target
Staurosporine	P-glycoprotein 1	transporter
Staurosporine	Muscarinic acetylcholine receptor M1	target
Staurosporine	Protein kinase C	target
Gabaculine	Ornithine aminotransferase, mitochondrial	target
Gabaculine	Glutamate-1-semialdehyde 2,1-aminomutase	target
Aminooxyacetic acid	Serine--pyruvate aminotransferase	target
3,5-Dinitrocatechol	Catechol O-methyltransferase	target
Olomoucine	Cyclin-dependent kinase 2	target
Olomoucine	Cyclin-dependent kinase 5	target
Olomoucine	Cyclin-dependent kinase 1	target
Olomoucine	Mitogen-activated protein kinase 1	target
K-252a	Hepatocyte growth factor receptor	target
K-252a	Dual specificity mitogen-activated protein kinase kinase 1	target
7-Nitroindazole	Nitric oxide synthase, endothelial	target
7-Nitroindazole	Nitric oxide synthase, inducible	target
7-Nitroindazole	Nitric oxide synthase, brain	target
Ilomastat	Lethal factor	target
Ilomastat	Disintegrin and metalloproteinase domain-containing protein 28	target
Ilomastat	Aggrecan core protein	target
Tolrestat	Aldose reductase	target
Tolrestat	Alcohol dehydrogenase [NADP(+)]	target
Tolrestat	Aldo-keto reductase family 1 member B10	target
Geldanamycin	Heat shock protein HSP 90-alpha	target
Geldanamycin	Heat shock protein HSP 90-beta	target
Geldanamycin	Endoplasmin	target
Trehalose-6-Phosphate	HTH-type transcriptional regulator TreR	target
Phosphoramidon	Neprilysin	target
Phosphoramidon	Kell blood group glycoprotein	target
LY-294002	Serine/threonine-protein kinase pim-1	target
LY-294002	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
Fusidic acid	Chloramphenicol acetyltransferase 3	target
Fusidic acid	Chloramphenicol acetyltransferase	target
Fusidic acid	Bile salt export pump	transporter
Fusidic acid	Canalicular multispecific organic anion transporter 1	transporter
Fusidic acid	Elongation factor G	target
Fusidic acid	Cytochrome P450 2D6	enzyme
Fusidic acid	Cytochrome P450 3A4	enzyme
Fusidic acid	UDP-glucuronosyltransferase 1-1	enzyme
Fusidic acid	ATP-binding cassette sub-family G member 2	transporter
Fusidic acid	Solute carrier organic anion transporter family member 1B1	transporter
Resveratrol	Transthyretin	carrier
Resveratrol	Ribosyldihydronicotinamide dehydrogenase [quinone]	target
Resveratrol	Prostaglandin G/H synthase 1	target
Resveratrol	Casein kinase II subunit alpha	target
Resveratrol	Prostaglandin G/H synthase 2	target
Resveratrol	NAD-dependent protein deacetylase sirtuin-1	target
Resveratrol	Cytochrome P450 1A1	enzyme
Resveratrol	Cytochrome P450 3A4	enzyme
Resveratrol	Cytochrome P450 1A2	enzyme
Resveratrol	Cytochrome P450 1B1	enzyme
Resveratrol	Arachidonate 15-lipoxygenase	target
Resveratrol	Arachidonate 5-lipoxygenase	target
Resveratrol	Aryl hydrocarbon receptor	target
Resveratrol	Phosphatidylinositol 4-kinase type 2-beta	target
Resveratrol	Integrin alpha-5	target
Resveratrol	Integrin beta-3	target
Resveratrol	Serum albumin	carrier
Resveratrol	Amyloid beta A4 protein	target
Resveratrol	Alpha-synuclein	target
Resveratrol	Estrogen receptor alpha	target
Resveratrol	Melatonin receptor type 1A	target
Resveratrol	Melatonin receptor type 1B	target
Resveratrol	C-type lectin domain family 14 member A	target
Resveratrol	Nuclear receptor subfamily 1 group I member 2	target
Resveratrol	Nuclear receptor subfamily 1 group I member 3	target
Resveratrol	Solute carrier family 2, facilitated glucose transporter member 1	target
Resveratrol	Carbonyl reductase [NADPH] 1	target
Resveratrol	Peroxisome proliferator-activated receptor alpha	target
Resveratrol	Peroxisome proliferator-activated receptor gamma	target
Resveratrol	RAC-alpha serine/threonine-protein kinase	target
Resveratrol	Far upstream element-binding protein 2	target
Resveratrol	Tyrosine--tRNA ligase, cytoplasmic	target
Resveratrol	Cytochrome P450 2D6	enzyme
Resveratrol	Cytochrome P450 2B6	enzyme
Resveratrol	Cytochrome P450 2C19	enzyme
Resveratrol	Cytochrome P450 2C9	enzyme
Kifunensine	Alpha-mannosidase 2	target
Kifunensine	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	target
Kifunensine	Mannosyl-oligosaccharide alpha-1,2-mannosidase	target
Pyrazole	Alcohol dehydrogenase 1C	target
Pyrazole	Estrogen receptor alpha	target
Pyrazole	Estrogen receptor beta	target
N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline	Cathepsin B	target
Calyculin A	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	target
Dazoxiben	Thromboxane-A synthase	target
Benzamidine	Urokinase-type plasminogen activator	target
Benzamidine	Trypsin-1	target
Benzamidine	Casein kinase II subunit alpha	target
Benzamidine	Kallikrein-6	target
Benzamidine	Trypsin-2	target
Benzamidine	Trypsin-3	target
Benzamidine	Copper transport protein ATOX1	target
Benzamidine	Enoyl-CoA delta isomerase 1, mitochondrial	target
Benzamidine	Trypsin	target
Benzamidine	Suppressor of tumorigenicity 14 protein	target
Benzamidine	Kallikrein-1	target
Imidazole	Monomeric sarcosine oxidase	target
Imidazole	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	target
Imidazole	Myoglobin	target
Imidazole	Nitric oxide synthase, inducible	target
Imidazole	Adenylate kinase 2, mitochondrial	target
Imidazole	Serine/threonine-protein kinase pim-1	target
Imidazole	Isopentenyl-diphosphate Delta-isomerase	target
Imidazole	Alpha,alpha-trehalose-phosphate synthase [UDP-forming]	target
Imidazole	Leukotriene A-4 hydrolase	target
Imidazole	Gephyrin	target
Imidazole	Acyl carrier protein	target
Imidazole	Sensor protein FixL	target
Imidazole	Cytochrome c	target
Imidazole	Circadian clock protein KaiB	target
Imidazole	Histidinol dehydrogenase	target
Imidazole	Acyl-CoA thioesterase I	target
Imidazole	A/G-specific adenine glycosylase	target
Imidazole	YopE regulator	target
Imidazole	Unconventional myosin-Ie	target
Imidazole	Meiotic recombination protein DMC1/LIM15 homolog	target
Imidazole	Guanine deaminase	target
Imidazole	Endo-1,4-beta-xylanase A	target
Imidazole	Bacterial hemoglobin	target
Imidazole	Molybdenum cofactor biosynthesis protein B	target
Imidazole	Uracil-DNA glycosylase inhibitor	target
Imidazole	Recombination protein RecR	target
Enalkiren	Renin	target
Ubenimex	Bacterial leucyl aminopeptidase	target
Ubenimex	Leukotriene A-4 hydrolase	target
Ubenimex	Solute carrier family 15 member 1	transporter
Ubenimex	Solute carrier family 15 member 2	transporter
Ubenimex	Dipeptidase 1	enzyme
Sparfosic acid	Aspartate carbamoyltransferase catalytic chain	target
Sparfosic acid	CAD protein	target
Eniluracil	Dihydropyrimidine dehydrogenase [NADP(+)]	target
Eniluracil	Aldehyde oxidase	target
Eniluracil	Xanthine dehydrogenase/oxidase	target
Palmitic Acid	Rhodopsin	target
Palmitic Acid	Serum albumin	carrier
Palmitic Acid	Palmitoyl-protein thioesterase 1	target
Palmitic Acid	Myelin P2 protein	target
Palmitic Acid	Fatty acid-binding protein, adipocyte	carrier
Palmitic Acid	Fatty acid-binding protein, epidermal	carrier
Palmitic Acid	Glycodelin	target
Palmitic Acid	Fatty acid-binding protein, heart	carrier
Palmitic Acid	Hepatocyte nuclear factor 4-gamma	target
Palmitic Acid	Lipid binding protein	target
Palmitic Acid	Cytochrome P450 2C8	target
Palmitic Acid	Trafficking protein particle complex subunit 3	target
Palmitic Acid	Fatty acid-binding protein TM_1468	target
Palmitic Acid	Fatty acid-binding protein, intestinal	carrier
Palmitic Acid	Alpha-lactalbumin	target
Palmitic Acid	Peroxisome proliferator-activated receptor alpha	target
Batimastat	Neutrophil collagenase	target
Batimastat	Macrophage metalloelastase	target
Batimastat	Matrix metalloproteinase-16	target
Batimastat	Disintegrin and metalloproteinase domain-containing protein 28	target
Batimastat	A disintegrin and metalloproteinase with thrombospondin motifs 5	target
S-Hexylglutathione	Lactoylglutathione lyase	target
S-Hexylglutathione	Glutathione S-transferase Mu 4	target
S-Hexylglutathione	Glutathione S-transferase P	target
S-Hexylglutathione	Glutathione S-transferase	target
S-Hexylglutathione	Glutathione S-transferase A1	target
S-Hexylglutathione	Glutathione S-transferase theta-2	target
S-Hexylglutathione	Glutathione S-transferase A1	enzyme
Nitroarginine	Nitric oxide synthase, endothelial	target
Nitroarginine	Nitric oxide synthase, brain	target
Maleic acid	Aspartate aminotransferase	target
Maleic acid	Trypanothione reductase	target
Maleic acid	Aspartate aminotransferase	target
Maleic acid	Aromatic-amino-acid aminotransferase	target
Maleic acid	Aspartate aminotransferase, cytoplasmic	target
Glyphosate	3-phosphoshikimate 1-carboxyvinyltransferase	target
Glyphosate	3-phosphoshikimate 1-carboxyvinyltransferase	target
Glyphosate	Cytochrome P450 19A1	target
Glyphosate	Serum albumin	carrier
5-iodotubercidin	Casein kinase I isoform gamma-2	target
5-iodotubercidin	Serine/threonine-protein kinase haspin	target
5-iodotubercidin	Mitogen-activated protein kinase 3	target
Metoprine	Histamine N-methyltransferase	target
Vildagliptin	Dipeptidyl peptidase 4	target
Vildagliptin	P-glycoprotein 1	transporter
Ximelagatran	Prothrombin	target
Ximelagatran	Cytochrome P450 2C9	enzyme
Stannsoporfin	Heme oxygenase 1	target
Stannsoporfin	Heme oxygenase 2	target
Belinostat	Histone deacetylase	target
Belinostat	Cytochrome P450 1A2	enzyme
Belinostat	UDP-glucuronosyltransferase 1-1	enzyme
Belinostat	Cytochrome P450 2C8	enzyme
Belinostat	Cytochrome P450 2C9	enzyme
Belinostat	P-glycoprotein 1	transporter
Belinostat	Cytochrome P450 3A4	enzyme
Elafin	Neutrophil elastase	target
Elafin	Myeloblastin	target
Elafin	Myeloperoxidase	enzyme
Oxypurinol	Xanthine dehydrogenase/oxidase	target
Ecabet	NADPH oxidase organizer 1	target
Ecabet	Urease subunit alpha	target
Dexlansoprazole	Potassium-transporting ATPase alpha chain 1	target
Dexlansoprazole	Cytochrome P450 2C19	enzyme
Dexlansoprazole	Cytochrome P450 3A4	enzyme
Dexlansoprazole	Potassium-transporting ATPase subunit beta	target
Dexlansoprazole	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	target
Abiraterone	Steroid 17-alpha-hydroxylase/17,20 lyase	target
Abiraterone	Serum albumin	carrier
Abiraterone	Alpha-1-acid glycoprotein 1	carrier
Abiraterone	Cytochrome P450 3A4	enzyme
Abiraterone	Bile salt sulfotransferase	enzyme
Abiraterone	Multidrug resistance-associated protein 1	transporter
Abiraterone	Cytochrome P450 2D6	enzyme
Abiraterone	Cytochrome P450 2C8	enzyme
Abiraterone	Cytochrome P450 1A2	enzyme
Abiraterone	Cytochrome P450 2C19	enzyme
Abiraterone	Cytochrome P450 2C9	enzyme
Abiraterone	Cytochrome P450 3A5	enzyme
Abiraterone	Solute carrier organic anion transporter family member 1B1	transporter
Alogliptin	Dipeptidyl peptidase 4	target
Alogliptin	Cytochrome P450 3A4	enzyme
Alogliptin	Cytochrome P450 2D6	enzyme
Rivaroxaban	Coagulation factor X	target
Rivaroxaban	Cytochrome P450 3A4	enzyme
Rivaroxaban	Cytochrome P450 2J2	enzyme
Rivaroxaban	P-glycoprotein 1	transporter
Rivaroxaban	Cytochrome P450 3A5	enzyme
Rivaroxaban	ATP-binding cassette sub-family G member 2	transporter
Eflornithine	Ornithine decarboxylase	target
Simeprevir	NS3 protease	target
Simeprevir	Serum albumin	carrier
Simeprevir	Cytochrome P450 1A2	enzyme
Simeprevir	P-glycoprotein 1	transporter
Simeprevir	Solute carrier organic anion transporter family member 1B1	transporter
Simeprevir	Solute carrier organic anion transporter family member 1B3	transporter
Simeprevir	Cytochrome P450 3A4	enzyme
Simeprevir	Canalicular multispecific organic anion transporter 1	transporter
Simeprevir	ATP-binding cassette sub-family G member 2	transporter
Simeprevir	Solute carrier organic anion transporter family member 2B1	transporter
Simeprevir	Sodium/bile acid cotransporter	transporter
Simeprevir	Bile salt export pump	transporter
Simeprevir	NS3/4A protein	target
Saxagliptin	Dipeptidyl peptidase 4	target
Saxagliptin	Cytochrome P450 3A4	enzyme
Saxagliptin	Cytochrome P450 3A5	enzyme
Saxagliptin	Multidrug resistance-associated protein 1	transporter
Saxagliptin	Solute carrier organic anion transporter family member 4C1	transporter
Saxagliptin	Solute carrier family 22 member 8	transporter
Idraparinux	Coagulation factor X	target
Tezacitabine	Ribonucleoside-diphosphate reductase large subunit	target
Tezacitabine	Thymidine phosphorylase	enzyme
Apixaban	Coagulation factor X	target
Apixaban	Cytochrome P450 3A4	enzyme
Apixaban	Cytochrome P450 1A2	enzyme
Apixaban	Cytochrome P450 2C8	enzyme
Apixaban	Cytochrome P450 2C9	enzyme
Apixaban	Cytochrome P450 2C19	enzyme
Apixaban	Cytochrome P450 2J2	enzyme
Apixaban	P-glycoprotein 1	transporter
Apixaban	ATP-binding cassette sub-family G member 2	transporter
Apixaban	Cytochrome P450 3A5	enzyme
Axitinib	Vascular endothelial growth factor receptor 1	target
Axitinib	Vascular endothelial growth factor receptor 2	target
Axitinib	Vascular endothelial growth factor receptor 3	target
Axitinib	Cytochrome P450 3A4	enzyme
Axitinib	Cytochrome P450 3A5	enzyme
Axitinib	Cytochrome P450 1A2	enzyme
Axitinib	Cytochrome P450 2C19	enzyme
Axitinib	UDP-glucuronosyltransferase 1-1	enzyme
Axitinib	P-glycoprotein 1	transporter
Axitinib	Solute carrier organic anion transporter family member 1B1	transporter
Otamixaban	Coagulation factor X	target
Aprotinin	Trypsin-1	target
Aprotinin	Chymotrypsinogen B	target
Aprotinin	Plasminogen	target
Aprotinin	Kallikrein-1	target
Aprotinin	Cholinesterase	enzyme
Dabigatran etexilate	Prothrombin	target
Dabigatran etexilate	P-glycoprotein 1	transporter
Dabigatran etexilate	Liver carboxylesterase 1	enzyme
Dabigatran etexilate	Cocaine esterase	enzyme
Dabigatran etexilate	UDP-glucuronosyltransferase 1-9	enzyme
Dabigatran etexilate	UDP-glucuronosyltransferase 2B7	enzyme
Dabigatran etexilate	UDP-glucuronosyltransferase 2B15	enzyme
Dabigatran etexilate	Ribosyldihydronicotinamide dehydrogenase [quinone]	enzyme
Dabigatran etexilate	Serum albumin	carrier
beta-Naphthoflavone	Cytochrome P450 1A2	enzyme
beta-Naphthoflavone	Estrogen receptor alpha	target
beta-Naphthoflavone	Steroid hormone receptor ERR1	target
beta-Naphthoflavone	COUP transcription factor 1	target
beta-Naphthoflavone	Aryl hydrocarbon receptor	target
beta-Naphthoflavone	Cytochrome P450 1B1	target
Bafilomycin A1	V-type proton ATPase catalytic subunit A	target
Besifloxacin	DNA topoisomerase 4 subunit A	target
Besifloxacin	DNA topoisomerase 4 subunit A	target
Besifloxacin	DNA gyrase subunit A	target
Besifloxacin	DNA gyrase subunit A	target
Besifloxacin	Cytochrome P450 1A2	enzyme
Raltegravir	UDP-glucuronosyltransferase 1-1	enzyme
Raltegravir	Integrase	target
Z-Val-Ala-Asp fluoromethyl ketone	Caspase-1	target
5-(2-methylpiperazine-1-sulfonyl)isoquinoline	cAMP-dependent protein kinase catalytic subunit alpha	target
5-(2-methylpiperazine-1-sulfonyl)isoquinoline	cAMP-dependent protein kinase inhibitor alpha	target
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline	Phenylethanolamine N-methyltransferase	target
Thiorphan	Neprilysin	target
Temocapril	Solute carrier family 15 member 1	transporter
Temocapril	Solute carrier organic anion transporter family member 1A2	transporter
Temocapril	Angiotensin-converting enzyme	target
Pitavastatin	Solute carrier organic anion transporter family member 1B1	transporter
Pitavastatin	Solute carrier organic anion transporter family member 1B3	transporter
Pitavastatin	UDP-glucuronosyltransferase 2B7	enzyme
Pitavastatin	UDP-glucuronosyltransferase 1-3	enzyme
Pitavastatin	Cytochrome P450 2C9	enzyme
Pitavastatin	Cytochrome P450 2C8	enzyme
Pitavastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Pitavastatin	Solute carrier organic anion transporter family member 2B1	transporter
Pitavastatin	Sodium/bile acid cotransporter	transporter
Pitavastatin	ATP-binding cassette sub-family G member 2	transporter
Pitavastatin	P-glycoprotein 1	transporter
Pitavastatin	Canalicular multispecific organic anion transporter 1	transporter
Pitavastatin	Serum albumin	carrier
Pitavastatin	Alpha-1-acid glycoprotein 1	carrier
Pitavastatin	Bile salt export pump	transporter
Pitavastatin	Integrin alpha-L	target
Rilpivirine	Cytochrome P450 3A4	enzyme
Rilpivirine	Reverse transcriptase/RNaseH	target
Rilpivirine	Nuclear receptor subfamily 1 group I member 2	target
Rilpivirine	Cytochrome P450 2C19	enzyme
Rilpivirine	Cytochrome P450 2B6	enzyme
Rilpivirine	P-glycoprotein 1	transporter
Rilpivirine	ATP-binding cassette sub-family G member 2	transporter
Rilpivirine	Solute carrier organic anion transporter family member 1B1	transporter
Rilpivirine	Solute carrier organic anion transporter family member 1B3	transporter
Rilpivirine	Serum albumin	carrier
Rilpivirine	Cytochrome P450 2D6	enzyme
Rilpivirine	Cytochrome P450 2C9	enzyme
Rilpivirine	Cytochrome P450 2C8	enzyme
Rilpivirine	Cytochrome P450 2E1	enzyme
Crizotinib	Cytochrome P450 3A4	enzyme
Crizotinib	Cytochrome P450 3A5	enzyme
Crizotinib	P-glycoprotein 1	transporter
Crizotinib	ALK tyrosine kinase receptor	target
Crizotinib	Hepatocyte growth factor receptor	target
Crizotinib	Cytochrome P450 2B6	enzyme
Crizotinib	Cytochrome P450 3A Subfamily	enzyme
Crizotinib	Serum albumin	carrier
Crizotinib	alpha1-acid glycoprotein	carrier
Crizotinib	Proto-oncogene tyrosine-protein kinase ROS	target
Crizotinib	Macrophage-stimulating protein receptor	target
Linagliptin	Dipeptidyl peptidase 4	target
Linagliptin	Cytochrome P450 3A4	enzyme
Linagliptin	P-glycoprotein 1	transporter
Linagliptin	Solute carrier family 22 member 1	transporter
Linagliptin	Solute carrier family 22 member 2	transporter
Linagliptin	Solute carrier family 22 member 3	transporter
Formestane	Cytochrome P450 3A4	enzyme
Dabrafenib	Cytochrome P450 3A4	enzyme
Dabrafenib	Cytochrome P450 2C8	enzyme
Dabrafenib	P-glycoprotein 1	transporter
Dabrafenib	ATP-binding cassette sub-family G member 2	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B1	transporter
Dabrafenib	Solute carrier organic anion transporter family member 1B3	transporter
Dabrafenib	Solute carrier family 22 member 6	transporter
Dabrafenib	Solute carrier family 22 member 8	transporter
Dabrafenib	Serine/threonine-protein kinase B-raf	target
Dabrafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Dabrafenib	Serine/threonine-protein kinase SIK1	target
Dabrafenib	Serine/threonine-protein kinase Nek11	target
Dabrafenib	LIM domain kinase 1	target
Dabrafenib	Cytochrome P450 2B6	enzyme
Dabrafenib	Cytochrome P450 2C9	enzyme
Dabrafenib	Cytochrome P450 2C19	enzyme
Dabrafenib	Cytochrome P450 1A2	enzyme
Dabrafenib	Serum albumin	carrier
Dabrafenib	Solute carrier organic anion transporter family member 1A2	transporter
Dabrafenib	Solute carrier family 22 member 2	transporter
Dabrafenib	UDP-glucuronosyltransferase 1-1	enzyme
Dolutegravir	UDP-glucuronosyltransferase 1-1	enzyme
Dolutegravir	Cytochrome P450 3A Subfamily	enzyme
Dolutegravir	Integrase	target
Dolutegravir	Solute carrier family 22 member 2	transporter
Dolutegravir	UDP-glucuronosyltransferase 1-3	enzyme
Dolutegravir	UDP-glucuronosyltransferase 1-9	enzyme
Dolutegravir	ATP-binding cassette sub-family G member 2	transporter
Dolutegravir	Solute carrier family 22 member 6	transporter
Dolutegravir	Solute carrier family 22 member 8	transporter
Dolutegravir	P-glycoprotein 1	transporter
Dolutegravir	Multidrug and toxin extrusion protein 1	transporter
Dolutegravir	Serum albumin	carrier
Dolutegravir	alpha1-acid glycoprotein	carrier
Eliglustat	Ceramide glucosyltransferase	target
Eliglustat	Cytochrome P450 2D6	enzyme
Eliglustat	Cytochrome P450 3A4	enzyme
Eliglustat	P-glycoprotein 1	transporter
Idelalisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
Idelalisib	ATP-binding cassette sub-family G member 2	transporter
Idelalisib	P-glycoprotein 1	transporter
Idelalisib	Aldehyde oxidase	enzyme
Idelalisib	Cytochrome P450 2C8	enzyme
Idelalisib	Cytochrome P450 2C19	enzyme
Idelalisib	Cytochrome P450 2B6	enzyme
Idelalisib	Cytochrome P450 3A4	enzyme
Idelalisib	Solute carrier organic anion transporter family member 1B1	transporter
Idelalisib	Solute carrier organic anion transporter family member 1B3	transporter
Idelalisib	Cytochrome P450 3A5	enzyme
Idelalisib	Cytochrome P450 3A43	enzyme
Idelalisib	Cytochrome P450 3A7	enzyme
Idelalisib	UDP-glucuronosyltransferase 1-4	enzyme
Avibactam	Canalicular multispecific organic anion transporter 1	transporter
Avibactam	Solute carrier family 22 member 8	transporter
Avibactam	Beta-lactamase TEM	target
Avibactam	Beta-lactamase CTX-M	target
Avibactam	Beta-lactamase	target
Avibactam	Beta-lactamase SHV-1	target
Avibactam	Beta-lactamase SHV-2	target
Avibactam	Beta-lactamase SHV-1	target
Avibactam	Class D OXA-48 carbapenemase	target
Avibactam	Carbapenem-hydrolyzing beta-lactamase KPC	target
Avibactam	Beta-lactamase CTX-M-15	target
Avibactam	Extended-spectrum beta-lactamase PER-1	target
Ceritinib	ALK tyrosine kinase receptor	target
Ceritinib	P-glycoprotein 1	transporter
Ceritinib	Cytochrome P450 2C9	enzyme
Ceritinib	Cytochrome P450 3A4	enzyme
Cobicistat	Cytochrome P450 2D6	enzyme
Cobicistat	P-glycoprotein 1	transporter
Cobicistat	ATP-binding cassette sub-family G member 2	transporter
Cobicistat	Cytochrome P450 3A5	enzyme
Cobicistat	Cytochrome P450 3A7	enzyme
Cobicistat	Solute carrier organic anion transporter family member 1B1	transporter
Cobicistat	Solute carrier organic anion transporter family member 1B3	transporter
Cobicistat	Cytochrome P450 3A4	target
Cobicistat	Cytochrome P450 3A4	enzyme
Cobicistat	Cytochrome P450 3A5	target
Cobicistat	Cytochrome P450 3A7	target
Palbociclib	Cyclin-dependent kinase 4	target
Palbociclib	Cyclin-dependent kinase 6	target
Palbociclib	Cytochrome P450 3A4	enzyme
Palbociclib	Bile salt sulfotransferase	enzyme
Palbociclib	P-glycoprotein 1	transporter
Palbociclib	ATP-binding cassette sub-family G member 2	transporter
Palbociclib	Serum albumin	carrier
Palbociclib	Solute carrier family 22 member 1	transporter
Olaparib	Poly [ADP-ribose] polymerase 1	target
Olaparib	Cytochrome P450 3A4	enzyme
Olaparib	Cytochrome P450 2B6	enzyme
Olaparib	Poly [ADP-ribose] polymerase 2	target
Olaparib	Poly [ADP-ribose] polymerase 3	target
Olaparib	Cytochrome P450 3A5	enzyme
Olaparib	P-glycoprotein 1	transporter
Olaparib	ATP-binding cassette sub-family G member 2	transporter
Olaparib	Aldo-keto reductase family 1 member C3	target
Olaparib	UDP-glucuronosyltransferase 1-1	enzyme
Olaparib	Serum albumin	carrier
Olaparib	Alpha-1-acid glycoprotein 1	carrier
Edoxaban	Coagulation factor X	target
Edoxaban	P-glycoprotein 1	transporter
Lenvatinib	Vascular endothelial growth factor receptor 1	target
Lenvatinib	Vascular endothelial growth factor receptor 2	target
Lenvatinib	Vascular endothelial growth factor receptor 3	target
Lenvatinib	Fibroblast growth factor receptor 1	target
Lenvatinib	Fibroblast growth factor receptor 2	target
Lenvatinib	Fibroblast growth factor receptor 3	target
Lenvatinib	Fibroblast growth factor receptor 4	target
Lenvatinib	Platelet-derived growth factor receptor alpha	target
Lenvatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Lenvatinib	Mast/stem cell growth factor receptor Kit	target
Lenvatinib	P-glycoprotein 1	transporter
Lenvatinib	ATP-binding cassette sub-family G member 2	transporter
Lenvatinib	Cytochrome P450 3A4	enzyme
Lenvatinib	Aldehyde oxidase	enzyme
Lenvatinib	Cytochrome P450 2C8	enzyme
Lenvatinib	Cytochrome P450 2C9	enzyme
Lenvatinib	Cytochrome P450 1A2	enzyme
Lenvatinib	Cytochrome P450 2B6	enzyme
Lenvatinib	Cytochrome P450 2C19	enzyme
Lenvatinib	Solute carrier family 22 member 6	transporter
Lenvatinib	Solute carrier family 22 member 8	transporter
Lenvatinib	Solute carrier family 22 member 2	transporter
Lenvatinib	Solute carrier organic anion transporter family member 1B1	transporter
Lenvatinib	Bile salt export pump	transporter
Lenvatinib	Cytochrome P450 2D6	enzyme
Lenvatinib	Solute carrier organic anion transporter family member 1B3	transporter
Nintedanib	Vascular endothelial growth factor receptor 1	target
Nintedanib	Vascular endothelial growth factor receptor 2	target
Nintedanib	Vascular endothelial growth factor receptor 3	target
Nintedanib	Platelet-derived growth factor receptor alpha	target
Nintedanib	Platelet-derived growth factor receptor beta	target
Nintedanib	Fibroblast growth factor receptor 1	target
Nintedanib	Fibroblast growth factor receptor 2	target
Nintedanib	Fibroblast growth factor receptor 3	target
Nintedanib	Receptor-type tyrosine-protein kinase FLT3	target
Nintedanib	Tyrosine-protein kinase Lck	target
Nintedanib	Tyrosine-protein kinase Lyn	target
Nintedanib	Proto-oncogene tyrosine-protein kinase Src	target
Nintedanib	P-glycoprotein 1	transporter
Nintedanib	Cytochrome P450 3A4	enzyme
Nintedanib	Solute carrier family 22 member 1	transporter
Nintedanib	Serum albumin	carrier
Nintedanib	UDP-glucuronosyltransferase 1-1	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-7	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-8	enzyme
Nintedanib	UDP-glucuronosyltransferase 1-10	enzyme
Nintedanib	ATP-binding cassette sub-family G member 2	transporter
Methylene blue	Guanylate cyclase soluble subunit alpha-2	target
Methylene blue	Nitric oxide synthase, brain	target
Methylene blue	UDP-glucuronosyltransferase 1-4	enzyme
Methylene blue	UDP-glucuronosyltransferase 1-9	enzyme
Methylene blue	Cytochrome P450 1A2	enzyme
Methylene blue	Cytochrome P450 2B6	enzyme
Methylene blue	Cytochrome P450 2C8	enzyme
Methylene blue	Cytochrome P450 2C9	enzyme
Methylene blue	Cytochrome P450 2C19	enzyme
Methylene blue	Cytochrome P450 3A4	enzyme
Methylene blue	Cytochrome P450 3A5	enzyme
Methylene blue	Serum albumin	carrier
Methylene blue	P-glycoprotein 1	transporter
Methylene blue	Solute carrier family 22 member 2	transporter
Methylene blue	Multidrug and toxin extrusion protein 2	transporter
Methylene blue	Multidrug and toxin extrusion protein 1	transporter
Methylene blue	Flavin reductase (NADPH)	enzyme
Methylene blue	Cytochrome P450 2D6	enzyme
Osimertinib	Epidermal growth factor receptor	target
Osimertinib	P-glycoprotein 1	transporter
Osimertinib	ATP-binding cassette sub-family G member 2	transporter
Osimertinib	Cytochrome P450 3A4	enzyme
Osimertinib	Cytochrome P450 1A2	enzyme
Mersalyl	Alkaline phosphatase, tissue-nonspecific isozyme	target
Mersalyl	Aquaporin-1	target
Mersalyl	Monocarboxylate transporter 1	target
Mersalyl	Inter-alpha-trypsin inhibitor heavy chain H1	enzyme
Mersalyl	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	enzyme
Enalaprilat	Angiotensin-converting enzyme	target
Enalaprilat	B1 bradykinin receptor	target
Antithrombin III human	Antithrombin-III	target
Candoxatrilat	Neprilysin	target
Opicapone	Cytochrome P450 2C19	enzyme
Opicapone	Cytochrome P450 2C8	enzyme
Opicapone	Catechol O-methyltransferase	target
Opicapone	Solute carrier organic anion transporter family member 1B1	transporter
Opicapone	P-glycoprotein 1	transporter
Opicapone	ATP-binding cassette sub-family G member 2	transporter
Opicapone	Solute carrier organic anion transporter family member 1B3	transporter
Opicapone	Solute carrier organic anion transporter family member 2B1	transporter
Opicapone	Cytochrome P450 2C9	enzyme
Opicapone	Cytochrome P450 1A2	enzyme
Opicapone	Cytochrome P450 2B6	enzyme
Curcumin	Peroxisome proliferator-activated receptor gamma	target
Curcumin	Vitamin D3 receptor	target
Curcumin	Multidrug resistance-associated protein 5	target
Curcumin	Carbonyl reductase [NADPH] 1	target
Curcumin	Glutathione S-transferase P	target
Curcumin	Cytochrome P450 2C9	enzyme
Curcumin	Cytochrome P450 3A4	enzyme
Curcumin	Cytochrome P450 2B6	enzyme
Curcumin	Cytochrome P450 1A2	enzyme
Curcumin	Cytochrome P450 2D6	enzyme
Curcumin	Glutathione S-transferase A1	enzyme
Curcumin	Glutathione S-transferase Mu 1	enzyme
Curcumin	Glutathione S-transferase P	enzyme
Curcumin	P-glycoprotein 1	transporter
Talazoparib	Poly [ADP-ribose] polymerase 1	target
Talazoparib	Poly [ADP-ribose] polymerase 2	target
Talazoparib	P-glycoprotein 1	transporter
Talazoparib	ATP-binding cassette sub-family G member 2	transporter
6-O-benzylguanine	Cytochrome P450 3A4	enzyme
Cantharidin	Aryl hydrocarbon receptor	target
Relebactam	Solute carrier family 22 member 8	transporter
Relebactam	Solute carrier family 22 member 11	transporter
Relebactam	Multidrug and toxin extrusion protein 1	transporter
Relebactam	Multidrug and toxin extrusion protein 2	transporter
Relebactam	Beta-lactamase TEM	target
Relebactam	Beta-lactamase SHV-1	target
Relebactam	Beta-lactamase CTX-M	target
Relebactam	Beta-lactamase (KPC-2)	target
Relebactam	Beta-lactamase	target
Nitroaspirin	Prostaglandin G/H synthase 1	target
Nafamostat	Intercellular adhesion molecule 1	target
Nafamostat	Trypsin-1	target
Nafamostat	Kallikrein-1	target
Nafamostat	Prothrombin	target
Nafamostat	Coagulation factor X	target
Nafamostat	Coagulation factor XII	target
Nafamostat	Solute carrier family 22 member 1	transporter
Nafamostat	Solute carrier family 22 member 2	transporter
Benserazide	Aromatic-L-amino-acid decarboxylase	target
Gabexate	Trypsin-1	enzyme
Gabexate	Complement C1s subcomponent	enzyme
Gabexate	Complement C1r subcomponent	enzyme
Gabexate	Plasma kallikrein	target
Gabexate	Prothrombin	target
Gabexate	Plasminogen	target
Zofenopril	Angiotensin-converting enzyme	target
Rhein	Oxysterols receptor LXR-alpha	target
Rhein	Oxysterols receptor LXR-beta	target
Rhein	Arylamine N-acetyltransferase	target
Rhein	Arachidonate 5-lipoxygenase	target
Rhein	Cytochrome P450 1A2	enzyme
Rhein	Cytochrome P450 3A Subfamily	enzyme
Rhein	Cytochrome P450 2E1	enzyme
Rhein	Cytochrome P450 2C9	enzyme
Rhein	Cytochrome P450 2D6	enzyme
Flurithromycin	Cytochrome P450 3A4	enzyme
Camostat	Trypsin-1	target
Camostat	Transmembrane protease serine 2	target
Camostat	Suppressor of tumorigenicity 14 protein	target
Camostat	Cholecystokinin	target
Calcium levulinate	Calmodulin	target
Calcium levulinate	Calsequestrin-1	target
Calcium levulinate	Calretinin	target
ABT-341	Dipeptidyl peptidase 4	target
Concanamycin A	P-glycoprotein 1	target
Concanamycin A	P-glycoprotein 1	transporter
Tenofovir	P-glycoprotein 1	transporter
Tenofovir	Solute carrier family 22 member 6	transporter
Tenofovir	Solute carrier family 22 member 8	transporter
Tenofovir	Multidrug resistance-associated protein 4	transporter
Tenofovir	Nucleoside diphosphate kinase A	enzyme
Tenofovir	Nucleoside diphosphate kinase B	enzyme
Tenofovir	Adenylate kinase isoenzyme 1	enzyme
Tenofovir	Adenylate kinase 2, mitochondrial	enzyme
Tenofovir	Reverse transcriptase/RNaseH	target
Tenofovir	Reverse transcriptase	target
Tenofovir	DNA polymerase	target
Tenofovir	Serum albumin	carrier
Lithium carbonate	Inositol monophosphatase 2	target
Lithium carbonate	Inositol monophosphatase 1	target
Lithium carbonate	Glycogen synthase kinase-3 beta	target
Lithium carbonate	Glutamate receptor 3	target
Lithium carbonate	Amiloride-sensitive sodium channel subunit alpha	transporter
Lithium carbonate	Amiloride-sensitive sodium channel subunit beta	transporter
Lithium carbonate	Amiloride-sensitive sodium channel subunit gamma	transporter
Magnesium levulinate	Sodium/potassium-transporting ATPase subunit alpha-1	target
Acifluorfen	Protoporphyrinogen oxidase	target
Acifluorfen	Protoporphyrinogen oxidase	target
acetylleucyl-leucyl-norleucinal	Proteasome subunit alpha type-7	target
Cholesterol sulfate	Nuclear receptor ROR-alpha	target
Zenarestat	Aldose reductase	target
Oseltamivir acid	Neuraminidase	target
Brequinar	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Meglutol	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Pimagedine	Nitric oxide synthase, inducible	target
Pimagedine	Aldose reductase	target
Pimagedine	Metalloproteinase inhibitor 3	target
Pimagedine	Solute carrier family 22 member 2	transporter
Pimagedine	Amiloride-sensitive amine oxidase [copper-containing]	target
Methoxy arachidonyl fluorophosphonate	Fatty-acid amide hydrolase 1	target
Famciclovir	DNA polymerase catalytic subunit	target
Famciclovir	Aldehyde oxidase	enzyme
Caspofungin	Solute carrier family 22 member 1	transporter
Caspofungin	P-glycoprotein 1	transporter
Caspofungin	Solute carrier family 22 member 6	transporter
Caspofungin	Solute carrier organic anion transporter family member 1B1	transporter
Caspofungin	Solute carrier organic anion transporter family member 1B3	transporter
Caspofungin	Cytochrome P450 3A4	enzyme
Caspofungin	1,3-beta-glucan synthase component FKS1	target
Fondaparinux	Antithrombin-III	target
Fondaparinux	Coagulation factor X	target
Fomepizole	Alcohol dehydrogenase 1A	target
Fomepizole	Alcohol dehydrogenase 1B	target
Fomepizole	Alcohol dehydrogenase 1C	target
Fomepizole	Catalase	target
Fomepizole	Cytochrome P450 2E1	enzyme
Fomepizole	Cytochrome P450 2A6	enzyme
Sunitinib	Platelet-derived growth factor receptor beta	target
Sunitinib	Vascular endothelial growth factor receptor 1	target
Sunitinib	Vascular endothelial growth factor receptor 2	target
Sunitinib	Vascular endothelial growth factor receptor 3	target
Sunitinib	Mast/stem cell growth factor receptor Kit	target
Sunitinib	Receptor-type tyrosine-protein kinase FLT3	target
Sunitinib	Macrophage colony-stimulating factor 1 receptor	target
Sunitinib	Platelet-derived growth factor receptor alpha	target
Sunitinib	Cytochrome P450 3A4	enzyme
Sunitinib	Cytochrome P450 3A5	enzyme
Sunitinib	Cytochrome P450 3A7	enzyme
Sunitinib	Multidrug resistance-associated protein 4	transporter
Sunitinib	P-glycoprotein 1	transporter
Sunitinib	Canalicular multispecific organic anion transporter 1	transporter
Sunitinib	ATP-binding cassette sub-family G member 2	transporter
Sunitinib	Hepatocyte growth factor receptor	target
Topiroxostat	Xanthine dehydrogenase/oxidase	target
Topiroxostat	ATP-binding cassette sub-family G member 2	transporter
Topiroxostat	Serum albumin	carrier
Topiroxostat	Alpha-1-acid glycoprotein 1	carrier
Topiroxostat	Cytochrome P450 2C8	enzyme
Topiroxostat	Cytochrome P450 2C9	enzyme
Topiroxostat	Cytochrome P450 1A1	enzyme
Topiroxostat	Cytochrome P450 3A4	enzyme
Topiroxostat	Cytochrome P450 2C19	enzyme
Topiroxostat	Solute carrier family 22 member 8	transporter
Topiroxostat	Solute carrier family 22 member 6	transporter
Topiroxostat	UDP-glucuronosyltransferase 1-9	enzyme
D-Eritadenine	Adenosylhomocysteinase	target
Myxothiazol	Cytochrome b-c1 complex subunit 1, mitochondrial	target
Rupintrivir	Genome polyprotein	target
Ranirestat	Aldose reductase	target
Arylacenamide	HCG20471, isoform CRA_c	target
Human C1-esterase inhibitor	Complement C1r subcomponent	target
Human C1-esterase inhibitor	Complement C1s subcomponent	target
Human C1-esterase inhibitor	Plasma kallikrein	target
Human C1-esterase inhibitor	Coagulation factor XII	target
Human C1-esterase inhibitor	Prothrombin	target
Human C1-esterase inhibitor	Coagulation factor XI	target
Human C1-esterase inhibitor	Tissue-type plasminogen activator	target
Lonafarnib	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	target
Lonafarnib	P-glycoprotein 1	transporter
Lonafarnib	Protein farnesyltransferase subunit beta	target
Lonafarnib	Cytochrome P450 3A Subfamily	enzyme
Lonafarnib	Cytochrome P450 2C8	enzyme
Lonafarnib	Cytochrome P450 2C19	enzyme
Lonafarnib	Cytochrome P450 1A2	enzyme
Lonafarnib	Cytochrome P450 2A6	enzyme
Lonafarnib	Cytochrome P450 2C9	enzyme
Lonafarnib	Cytochrome P450 2E1	enzyme
Lonafarnib	Solute carrier organic anion transporter family member 1B1	transporter
Lonafarnib	Solute carrier organic anion transporter family member 1B3	transporter
Lonafarnib	ATP-binding cassette sub-family G member 2	transporter
Lonafarnib	Cytochrome P450 3A4	enzyme
Lonafarnib	Cytochrome P450 3A5	enzyme
Lonafarnib	Canalicular multispecific organic anion transporter 1	transporter
Desirudin	Carboxypeptidase A1	enzyme
Asunaprevir	Genome polyprotein	target
Asunaprevir	Cytochrome P450 3A4	enzyme
Asunaprevir	Cytochrome P450 3A5	enzyme
Asunaprevir	Cytochrome P450 2A6	enzyme
Asunaprevir	Cytochrome P450 2B6	enzyme
Asunaprevir	Cytochrome P450 2C9	enzyme
Asunaprevir	Cytochrome P450 2C19	enzyme
Asunaprevir	Cytochrome P450 2D6	enzyme
Asunaprevir	Solute carrier organic anion transporter family member 1B1	transporter
Asunaprevir	Solute carrier organic anion transporter family member 1B3	transporter
Asunaprevir	Solute carrier organic anion transporter family member 2B1	transporter
Asunaprevir	P-glycoprotein 1	transporter
Adavosertib	Wee1-like protein kinase	target
Tosedostat	Puromycin-sensitive aminopeptidase	target
Tosedostat	Leukotriene A-4 hydrolase	target
Bempedoic acid	ATP-citrate synthase	target
Bempedoic acid	Very long-chain acyl-CoA synthetase	enzyme
Bempedoic acid	Solute carrier organic anion transporter family member 1B1	transporter
Bempedoic acid	Canalicular multispecific organic anion transporter 2	transporter
Bempedoic acid	Solute carrier organic anion transporter family member 1B3	transporter
Bempedoic acid	UDP-glucuronosyltransferase 2B7	enzyme
Bempedoic acid	NUAK family SNF1-like kinase 2	enzyme
Entrectinib	Cytochrome P450 3A4	enzyme
Entrectinib	P-glycoprotein 1	transporter
Entrectinib	High affinity nerve growth factor receptor	target
Entrectinib	BDNF/NT-3 growth factors receptor	target
Entrectinib	NT-3 growth factor receptor	target
Entrectinib	Proto-oncogene tyrosine-protein kinase ROS	target
Entrectinib	Tyrosine-protein kinase JAK2	target
Entrectinib	Activated CDC42 kinase 1	target
Vaborbactam	Beta-lactamase	target
Vaborbactam	Carbapenem-hydrolyzing beta-lactamase KPC	target
Vaborbactam	Beta-lactamase (KPC-2)	target
Vaborbactam	Beta-lactamase CTX-M	target
Vaborbactam	Beta-lactamase (blaSHV)	target
Vaborbactam	Beta-lactamase SHV-1	target
Vaborbactam	Beta-lactamase TEM	target
Vaborbactam	Beta-lactamase (MIR-1)	target
Vaborbactam	Beta-lactamase	target
Obatoclax	Apoptosis regulator Bcl-2	target
Betrixaban	P-glycoprotein 1	transporter
Betrixaban	Coagulation factor X	target
Betrixaban	Potassium voltage-gated channel subfamily H member 2	transporter
Ivosidenib	Isocitrate dehydrogenase [NADP] cytoplasmic	target
Ivosidenib	Cytochrome P450 3A4	enzyme
Ivosidenib	Cytochrome P450 2B6	enzyme
Ivosidenib	Cytochrome P450 2C9	enzyme
Ivosidenib	Cytochrome P450 2C8	enzyme
Ivosidenib	Solute carrier family 22 member 8	transporter
Ivosidenib	P-glycoprotein 1	transporter
CPI-1205	Histone-lysine N-methyltransferase EZH2	target
Zanubrutinib	Cytochrome P450 3A4	enzyme
Zanubrutinib	P-glycoprotein 1	transporter
Zanubrutinib	Cytochrome P450 2B6	enzyme
Zanubrutinib	Tyrosine-protein kinase BTK	target
Zanubrutinib	Epidermal growth factor receptor	target
Zanubrutinib	Receptor tyrosine-protein kinase erbB-2	target
Zanubrutinib	Receptor tyrosine-protein kinase erbB-4	target
Zanubrutinib	Tyrosine-protein kinase ITK/TSK	target
Zanubrutinib	Cytoplasmic tyrosine-protein kinase BMX	target
Zanubrutinib	Tyrosine-protein kinase JAK2	target
Zanubrutinib	Tyrosine-protein kinase Tec	target
Zanubrutinib	Tyrosine-protein kinase Blk	target
Zanubrutinib	Tyrosine-protein kinase JAK3	target
Zanubrutinib	Protein-tyrosine kinase 6	target
Zanubrutinib	Tyrosine-protein kinase Fgr	target
Zanubrutinib	Tyrosine-protein kinase FRK	target
Zanubrutinib	Tyrosine-protein kinase Lck	target
Zanubrutinib	Tyrosine-protein kinase TXK	target
Zanubrutinib	Cytochrome P450 3A Subfamily	enzyme
Upadacitinib	Tyrosine-protein kinase JAK1	target
Upadacitinib	Cytochrome P450 3A4	enzyme
Upadacitinib	Cytochrome P450 2D6	enzyme
Upadacitinib	P-glycoprotein 1	transporter
Upadacitinib	ATP-binding cassette sub-family G member 2	transporter
Upadacitinib	Solute carrier organic anion transporter family member 1B1	transporter
p-Hydroxymercuribenzoic acid	Carbonic anhydrase 2	target
2-deoxy-2,3-dehydro-N-acetylneuraminic acid	Hemagglutinin-neuraminidase	target
2-deoxy-2,3-dehydro-N-acetylneuraminic acid	Sialidase	target
2-deoxy-2,3-dehydro-N-acetylneuraminic acid	Neuraminidase	target
2-deoxy-2,3-dehydro-N-acetylneuraminic acid	Hemagglutinin-neuraminidase	target
2-deoxy-2,3-dehydro-N-acetylneuraminic acid	Sialidase-2	target
Thiocitrulline	Nitric oxide synthase, inducible	target
N(G)-Iminoethylornithine	Nitric oxide synthase, endothelial	target
R-82913	Gag-Pol polyprotein	target
R-82913	Gag-Pol polyprotein	target
H-89	cAMP-dependent protein kinase catalytic subunit alpha	target
H-89	cAMP-dependent protein kinase inhibitor alpha	target
H-89	Serine/threonine-protein kinase haspin	target
H-89	Interferon-induced, double-stranded RNA-activated protein kinase	target
Zopolrestat	Aldo-keto reductase family 1 member B10	target
Zopolrestat	Aldose reductase	target
CGS-27023	Macrophage metalloelastase	target
CGS-27023	Interstitial collagenase	target
Bisindolylmaleimide VIII	3-phosphoinositide-dependent protein kinase 1	target
Bisindolylmaleimide VIII	Myotonin-protein kinase	target
CP-320626	Glycogen phosphorylase, muscle form	target
GW-813893	Prothrombin	target
GW-813893	Coagulation factor X	target
Bisindolylmaleimide I	Serine/threonine-protein kinase pim-1	target
Bisindolylmaleimide I	3-phosphoinositide-dependent protein kinase 1	target
Bisindolylmaleimide I	Protein kinase C iota type	target
5-Benzylacyclouridine	Uridine phosphorylase	target
5-Benzylacyclouridine	Uridine phosphorylase 1	target
Dorsomorphin	Activin receptor type-1	target
Dorsomorphin	Peptidyl-prolyl cis-trans isomerase FKBP1A	target
Adenosine 5'-methylenediphosphate	DNA	target
Adenosine 5'-methylenediphosphate	Ribose-phosphate pyrophosphokinase	target
Adenosine 5'-methylenediphosphate	MutT/nudix family protein	target
Adenosine 5'-methylenediphosphate	Protein UshA	target
Methyldopa	Alpha-2A adrenergic receptor	target
Methyldopa	Catechol O-methyltransferase	enzyme
Methyldopa	Solute carrier family 15 member 1	transporter
Methyldopa	Aromatic-L-amino-acid decarboxylase	target
Methyldopa	Serum albumin	carrier
Methyldopa	Sulfotransferase	enzyme
Methyldopa	Dopamine beta-hydroxylase	enzyme
Methyldopa	Phenylethanolamine N-methyltransferase	enzyme
Methyldopa	Aromatic-L-amino-acid decarboxylase	enzyme
Vigabatrin	4-aminobutyrate aminotransferase, mitochondrial	target
Vigabatrin	Proton-coupled amino acid transporter 1	transporter
Vigabatrin	Cytochrome P450 2C9	enzyme
Zinc protoporphyrin	Cytochrome c	target
Telaprevir	Cytochrome P450 3A4	enzyme
Telaprevir	NS3/4A protein	target
Telaprevir	P-glycoprotein 1	transporter
Telaprevir	Serum albumin	carrier
Telaprevir	Alpha-1-acid glycoprotein 1	carrier
Telaprevir	Solute carrier organic anion transporter family member 1B1	target
Telaprevir	Solute carrier organic anion transporter family member 2B1	target
Boceprevir	Cytochrome P450 3A4	enzyme
Boceprevir	Cytochrome P450 3A5	enzyme
Boceprevir	P-glycoprotein 1	transporter
Boceprevir	NS3/4A protein	target
Conestat alfa	Complement C1r subcomponent	target
Conestat alfa	Complement C1s subcomponent	target
Conestat alfa	Plasma kallikrein	target
Conestat alfa	Coagulation factor XII	target
Conestat alfa	Prothrombin	target
Conestat alfa	Coagulation factor XI	target
Conestat alfa	Tissue-type plasminogen activator	target
Tipranavir	Human immunodeficiency virus type 1 protease	target
Tipranavir	Cytochrome P450 3A4	enzyme
Tipranavir	Cytochrome P450 2D6	enzyme
Tipranavir	Cytochrome P450 2C19	enzyme
Tipranavir	Bile salt export pump	transporter
Tipranavir	UDP-glucuronosyltransferase 1-1	enzyme
Tipranavir	Solute carrier organic anion transporter family member 2B1	transporter
Tipranavir	Solute carrier organic anion transporter family member 1B1	transporter
Tipranavir	Solute carrier organic anion transporter family member 1B3	transporter
Tipranavir	P-glycoprotein 1	transporter
Epicaptopril	Angiotensin-converting enzyme	target
Epicaptopril	FEZ-1 protein	target
Epicaptopril	Carbapenem-hydrolyzing beta-lactamase BlaB-1	target
Epicaptopril	Metallo-beta-lactamase L1	target
Epicaptopril	Beta-lactamase	target
Epicaptopril	Organic hydroperoxide resistance protein, putative	target
Nirmatrelvir	Replicase polyprotein 1ab	target
Nirmatrelvir	Cytochrome P450 3A4	enzyme
Nirmatrelvir	P-glycoprotein 1	transporter
N-Ethylmaleimide	Galectin-10	target
Tirbanibulin	Proto-oncogene tyrosine-protein kinase Src	target
Tirbanibulin	Tubulin beta chain	target
Tirbanibulin	Cytochrome P450 3A4	enzyme
Tirbanibulin	Cytochrome P450 2C8	enzyme
Tirbanibulin	Cytochrome P450 1A2	enzyme
Tirbanibulin	Cytochrome P450 2B6	enzyme
Tirbanibulin	Cytochrome P450 2C9	enzyme
Tirbanibulin	Cytochrome P450 2C19	enzyme
Tirbanibulin	Cytochrome P450 2D6	enzyme
Tirbanibulin	Multidrug and toxin extrusion protein 1	transporter
Tirbanibulin	Multidrug and toxin extrusion protein 2	transporter
Tirbanibulin	Solute carrier organic anion transporter family member 1B1	transporter
Tirbanibulin	Solute carrier organic anion transporter family member 1B3	transporter
Tirbanibulin	Solute carrier family 22 member 1	transporter
Tirbanibulin	Solute carrier family 22 member 2	transporter
AR-9281	Bifunctional epoxide hydrolase 2	target
1,10-Phenanthroline	Methyl-accepting chemotaxis protein II	target
1,10-Phenanthroline	Metallo-beta-lactamase L1	target
Cidofovir	DNA polymerase catalytic subunit	target
Cidofovir	Solute carrier family 22 member 6	transporter
Cidofovir	Thymidine phosphorylase	enzyme
Miglustat	Ceramide glucosyltransferase	target
Acetyldigitoxin	Sodium/potassium-transporting ATPase subunit alpha-1	target
Pemetrexed	Thymidylate synthase	target
Pemetrexed	Dihydrofolate reductase	target
Pemetrexed	Trifunctional purine biosynthetic protein adenosine-3	target
Pemetrexed	Deoxycytidine kinase	enzyme
Pemetrexed	Bifunctional purine biosynthesis protein PURH	target
Pemetrexed	Equilibrative nucleoside transporter 1	enzyme
Pemetrexed	Solute carrier family 22 member 8	transporter
Pemetrexed	Folate transporter 1	transporter
Pemetrexed	Proton-coupled folate transporter	transporter
Pemetrexed	ATP-binding cassette sub-family G member 2	transporter
Pemetrexed	Multidrug resistance-associated protein 5	transporter
Pemetrexed	Solute carrier family 22 member 6	transporter
Pemetrexed	Serum albumin	carrier
Pemetrexed	Solute carrier family 22 member 11	transporter
Quinidine	Sodium channel protein type 5 subunit alpha	target
Quinidine	Alpha-1-acid glycoprotein 1	carrier
Quinidine	Potassium voltage-gated channel subfamily H member 2	target
Quinidine	Potassium channel subfamily K member 1	target
Quinidine	Potassium channel subfamily K member 6	target
Quinidine	Cytochrome P450 1A2	enzyme
Quinidine	Cytochrome P450 2E1	enzyme
Quinidine	Cytochrome P450 1A1	enzyme
Quinidine	Cytochrome P450 2D6	enzyme
Quinidine	Cytochrome P450 3A4	enzyme
Quinidine	Cytochrome P450 3A7	enzyme
Quinidine	Solute carrier family 22 member 2	transporter
Quinidine	Solute carrier family 22 member 1	transporter
Quinidine	Solute carrier family 22 member 5	transporter
Quinidine	P-glycoprotein 1	transporter
Quinidine	Solute carrier organic anion transporter family member 1A2	transporter
Quinidine	Solute carrier family 22 member 8	transporter
Quinidine	Canalicular multispecific organic anion transporter 1	transporter
Quinidine	Solute carrier family 22 member 4	transporter
Quinidine	Solute carrier organic anion transporter family member 1B1	transporter
Quinidine	Cytochrome P450 2B6	enzyme
Quinidine	Cytochrome P450 2C9	enzyme
Quinidine	Alpha-1A adrenergic receptor	target
Quinidine	Alpha-1B adrenergic receptor	target
Quinidine	Alpha-1D adrenergic receptor	target
Quinidine	Bile salt export pump	transporter
Quinidine	Cytochrome P450 2C8	enzyme
Quinidine	Serum albumin	carrier
Mycophenolic acid	Inosine-5'-monophosphate dehydrogenase 2	target
Mycophenolic acid	Inosine-5'-monophosphate dehydrogenase 1	target
Mycophenolic acid	UDP-glucuronosyltransferase 1-1	enzyme
Mycophenolic acid	UDP-glucuronosyltransferase 1-9	enzyme
Mycophenolic acid	UDP-glucuronosyltransferase 2B7	enzyme
Mycophenolic acid	UDP-glucuronosyltransferase 1-7	enzyme
Mycophenolic acid	UDP-glucuronosyltransferase 1-6	enzyme
Mycophenolic acid	Serum albumin	carrier
Mycophenolic acid	UDP-glucuronosyltransferase 1-8	enzyme
Mycophenolic acid	UDP-glucuronosyltransferase 1-10	enzyme
Mycophenolic acid	Cytochrome P450 3A4	enzyme
Mycophenolic acid	Cytochrome P450 3A5	enzyme
Mycophenolic acid	Cytochrome P450 2C8	enzyme
Novobiocin	DNA gyrase subunit B	target
Novobiocin	Solute carrier family 22 member 6	transporter
Novobiocin	Solute carrier family 22 member 8	transporter
Novobiocin	Solute carrier family 22 member 11	transporter
Novobiocin	ATP-binding cassette sub-family G member 2	transporter
Novobiocin	DNA topoisomerase 1	target
Novobiocin	Solute carrier organic anion transporter family member 1B1	transporter
Novobiocin	Solute carrier organic anion transporter family member 1B3	transporter
Novobiocin	Solute carrier organic anion transporter family member 2B1	transporter
Ouabain	Sodium/potassium-transporting ATPase subunit alpha-1	target
Ouabain	Solute carrier organic anion transporter family member 1A2	transporter
Ouabain	Solute carrier family 22 member 8	transporter
Ouabain	Solute carrier organic anion transporter family member 4C1	transporter
Ouabain	Solute carrier organic anion transporter family member 1B3	transporter
Ouabain	Solute carrier organic anion transporter family member 1C1	transporter
Ouabain	Solute carrier organic anion transporter family member 1B1	transporter
Ouabain	Sodium/potassium-transporting ATPase subunit alpha-2	target
Ouabain	Sodium/potassium-transporting ATPase subunit alpha-3	target
Leflunomide	Dihydroorotate dehydrogenase (quinone), mitochondrial	target
Leflunomide	Cytochrome P450 1A2	enzyme
Leflunomide	Cytochrome P450 2C9	enzyme
Leflunomide	Aryl hydrocarbon receptor	target
Leflunomide	Protein-tyrosine kinase 2-beta	target
Leflunomide	ATP-binding cassette sub-family G member 2	transporter
Desipramine	Muscarinic acetylcholine receptor M1	target
Desipramine	Sodium-dependent noradrenaline transporter	target
Desipramine	Beta-2 adrenergic receptor	target
Desipramine	Muscarinic acetylcholine receptor M2	target
Desipramine	Sodium-dependent serotonin transporter	target
Desipramine	Histamine H1 receptor	target
Desipramine	Beta-1 adrenergic receptor	target
Desipramine	Cytochrome P450 2D6	enzyme
Desipramine	Muscarinic acetylcholine receptor M3	target
Desipramine	Muscarinic acetylcholine receptor M4	target
Desipramine	Muscarinic acetylcholine receptor M5	target
Desipramine	Alpha-1 adrenergic receptors	target
Desipramine	5-hydroxytryptamine receptor 2A	target
Desipramine	Alpha-1-acid glycoprotein 1	carrier
Desipramine	Cytochrome P450 2B6	enzyme
Desipramine	Cytochrome P450 3A4	enzyme
Desipramine	Solute carrier family 22 member 2	transporter
Desipramine	Solute carrier family 22 member 1	transporter
Desipramine	Solute carrier family 22 member 3	transporter
Desipramine	Solute carrier family 22 member 5	transporter
Desipramine	P-glycoprotein 1	transporter
Desipramine	Solute carrier family 22 member 4	transporter
Desipramine	Cytochrome P450 1A2	enzyme
Desipramine	Cytochrome P450 2E1	enzyme
Desipramine	Sphingomyelin phosphodiesterase	target
Desipramine	5-hydroxytryptamine receptor 1A	target
Desipramine	5-hydroxytryptamine receptor 2C	target
Desipramine	Dopamine D2 receptor	target
Desipramine	Alpha-2 adrenergic receptors	target
Alrestatin	Aldose reductase	target
Daidzin	Aldehyde dehydrogenase, mitochondrial	target
Daidzin	ATP-binding cassette sub-family G member 2	transporter
S-Ethylisothiourea	Nitric oxide synthase oxygenase	target
S-Ethylisothiourea	Nitric oxide synthase, inducible	target
S-Ethylisothiourea	Nitric oxide synthase, endothelial	target
5'-S-methyl-5'-thioadenosine	Modification methylase RsrI	target
5'-S-methyl-5'-thioadenosine	S-methyl-5'-thioadenosine phosphorylase	target
Phosphonoacetic Acid	Alkaline phosphatase	target
Duvoglustat	Cyclomaltodextrin glucanotransferase	target
Duvoglustat	Beta-glucosidase A	target
Duvoglustat	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	target
Duvoglustat	Mannosyl-oligosaccharide alpha-1,2-mannosidase	target
Duvoglustat	Xylose isomerase	target
Phencyclidine	Glutamate receptor ionotropic, NMDA 3A	target
Phencyclidine	Sigma non-opioid intracellular receptor 1	target
Phencyclidine	Cytochrome P450 2B6	enzyme
Radicicol	Heat shock protein HSP 90-beta	target
Radicicol	Endoplasmin	target
Radicicol	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	target
Radicicol	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial	target
Radicicol	Virulence sensor histidine kinase PhoQ	target
1-deoxymannojirimycin	Alpha-mannosidase 2	target
Dipicolinic acid	4-hydroxy-tetrahydrodipicolinate reductase	target
Dipicolinic acid	4-hydroxy-tetrahydrodipicolinate reductase	target
Monastrol	Kinesin-like protein KIF11	target
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide	Calmodulin	target
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide	Troponin C, slow skeletal and cardiac muscles	target
N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide	Troponin I, cardiac muscle	target
Allosamidin	Chitinase B	target
Allosamidin	Chitinase A	target
2,5-di-tert-butylhydroquinone	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	target
Permethrin	Cytochrome P450 2B6	enzyme
Permethrin	Sodium channel protein type 1 subunit alpha	target
Permethrin	Estrogen receptor alpha	target
Permethrin	Nuclear receptor subfamily 1 group I member 2	target
Amonafide	DNA topoisomerase 2-alpha	target
Amonafide	DNA topoisomerase 2-beta	target
Tetrathiomolybdate	Amyloid beta A4 protein	target
Cetilistat	Pancreatic triacylglycerol lipase	target
Peramivir	Neuraminidase	target
Peramivir	Neuraminidase	target
Peramivir	Neuraminidase	target
Iobenguane	Sodium-dependent noradrenaline transporter	transporter
t-Butylhydroquinone	Hemagglutinin	target
t-Butylhydroquinone	Hemagglutinin	target
Dichlororibofuranosylbenzimidazole	Casein kinase II subunit alpha	target
Y-27632	cAMP-dependent protein kinase catalytic subunit alpha	target
Y-27632	cAMP-dependent protein kinase inhibitor alpha	target
Y-27632	Rho-associated protein kinase 1	target
Y-27632	Rho-associated protein kinase 2	target
Saracatinib	Cytochrome P450 3A4	enzyme
Phenethyl Isothiocyanate	Actin, aortic smooth muscle	target
Phenethyl Isothiocyanate	Actin, cytoplasmic 1	target
Phenethyl Isothiocyanate	ATP synthase subunit beta, mitochondrial	target
Phenethyl Isothiocyanate	ATP synthase subunit e, mitochondrial	target
Phenethyl Isothiocyanate	ATP synthase subunit g, mitochondrial	target
Phenethyl Isothiocyanate	Cytochrome b5 type B	target
Phenethyl Isothiocyanate	Diablo homolog, mitochondrial	target
Phenethyl Isothiocyanate	F-box only protein 41	target
Phenethyl Isothiocyanate	Heterogeneous nuclear ribonucleoprotein F	target
Phenethyl Isothiocyanate	Heterogeneous nuclear ribonucleoprotein K	target
Phenethyl Isothiocyanate	Heat shock 70 kDa protein 4	target
Phenethyl Isothiocyanate	Heat shock protein beta-1	target
Phenethyl Isothiocyanate	10 kDa heat shock protein, mitochondrial	target
Phenethyl Isothiocyanate	Heat shock protein 105 kDa	target
Phenethyl Isothiocyanate	NADH-ubiquinone oxidoreductase chain 1	target
Phenethyl Isothiocyanate	Nuclear migration protein nudC	target
Phenethyl Isothiocyanate	Pappalysin-1	target
Phenethyl Isothiocyanate	Proteasome subunit alpha type-3	target
Phenethyl Isothiocyanate	26S protease regulatory subunit 6A	target
Phenethyl Isothiocyanate	Ran-specific GTPase-activating protein	target
Phenethyl Isothiocyanate	Protein S100-A10	target
Phenethyl Isothiocyanate	Splicing factor 3A subunit 3	target
Phenethyl Isothiocyanate	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	target
Phenethyl Isothiocyanate	Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial	target
Phenethyl Isothiocyanate	Tumor protein D54	target
Phenethyl Isothiocyanate	Tropomyosin alpha-1 chain	target
Phenethyl Isothiocyanate	Tropomyosin alpha-3 chain	target
Phenethyl Isothiocyanate	Tropomyosin alpha-4 chain	target
Phenethyl Isothiocyanate	Tubulin alpha-1A chain	target
Phenethyl Isothiocyanate	Tubulin alpha 3C/D chain	target
Phenethyl Isothiocyanate	Tubulin alpha-4A chain	target
Phenethyl Isothiocyanate	Tubulin beta-1 chain	target
Phenethyl Isothiocyanate	Tubulin beta-2A chain	target
Phenethyl Isothiocyanate	Tubulin beta-3 chain	target
Phenethyl Isothiocyanate	Tubulin beta-4B chain	target
Phenethyl Isothiocyanate	Thioredoxin	target
Phenethyl Isothiocyanate	Ubiquitin carboxyl-terminal hydrolase isozyme L1	target
Phenethyl Isothiocyanate	Ubiquitin carboxyl-terminal hydrolase 14	target
Phenethyl Isothiocyanate	Transitional endoplasmic reticulum ATPase	target
Phenethyl Isothiocyanate	Vimentin	target
Phenethyl Isothiocyanate	14-3-3 protein beta/alpha	target
Phenethyl Isothiocyanate	14-3-3 protein epsilon	target
Phenethyl Isothiocyanate	14-3-3 protein eta	target
Phenethyl Isothiocyanate	14-3-3 protein theta	target
Phenethyl Isothiocyanate	14-3-3 protein zeta/delta	target
Hypericin	Serum albumin	carrier
Hypericin	Glutathione S-transferase A1	target
Hypericin	Glutathione S-transferase P	target
Baloxavir marboxil	UDP-glucuronosyltransferase 1-3	enzyme
Baloxavir marboxil	Cytochrome P450 3A4	enzyme
Baloxavir marboxil	Polymerase acidic protein	target
Baloxavir marboxil	P-glycoprotein 1	transporter
Baloxavir marboxil	Cytochrome P450 2B6	enzyme
Baloxavir marboxil	Cytochrome P450 2C8	enzyme
Baloxavir marboxil	ATP-binding cassette sub-family G member 2	transporter
Basifungin	Inositol phosphorylceramide synthase	target
Cilazaprilat	Angiotensin-converting enzyme	target
TMC-310911	HIV-1 protease	target
Berotralstat	Cytochrome P450 2D6	enzyme
Berotralstat	Cytochrome P450 3A4	enzyme
Berotralstat	P-glycoprotein 1	transporter
Berotralstat	ATP-binding cassette sub-family G member 2	transporter
Berotralstat	Plasma kallikrein	target
Ticlopidine	P2Y purinoceptor 12	target
Ticlopidine	Cytochrome P450 2C19	enzyme
Ticlopidine	Cytochrome P450 2B6	enzyme
Ticlopidine	Cytochrome P450 2C9	enzyme
Ticlopidine	Cytochrome P450 2D6	enzyme
Ticlopidine	Myeloperoxidase	enzyme
Ticlopidine	Cytochrome P450 1A2	enzyme
Ticlopidine	Cytochrome P450 2C8	enzyme
Ticlopidine	Cytochrome P450 2E1	enzyme
Idoxuridine	Thymidine kinase	target
Idoxuridine	DNA	target
Dapsone	Inactive dihydropteroate synthase 2	target
Dapsone	Dihydropteroate synthase 1	target
Dapsone	Cytochrome P450 2C9	enzyme
Dapsone	Cytochrome P450 2E1	enzyme
Dapsone	Cytochrome P450 3A4	enzyme
Dapsone	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Dapsone	Prostaglandin G/H synthase 1	enzyme
Dapsone	Prostaglandin G/H synthase 2	enzyme
Dapsone	Cytochrome P450 2C8	enzyme
Dapsone	Cytochrome P450 2C19	enzyme
Dapsone	Arylamine N-acetyltransferase 2	enzyme
Dapsone	Cytochrome P450 3A5	enzyme
Dapsone	Cytochrome P450 3A7	enzyme
Dapsone	Myeloperoxidase	enzyme
Dapsone	Cytochrome P450 2C18	enzyme
Raltitrexed	Thymidylate synthase	target
Raltitrexed	Folylpolyglutamate synthase, mitochondrial	target
Ethoxzolamide	Carbonic anhydrase 1	target
Ethoxzolamide	Solute carrier family 22 member 6	transporter
Ethoxzolamide	Carbonic anhydrase 2	target
Ethoxzolamide	Carbonic anhydrase 4	target
Ethoxzolamide	Carbonic anhydrase 7	target
Ethoxzolamide	Carbonic anhydrase 3	target
Capreomycin	16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA	target
Pimecrolimus	Peptidyl-prolyl cis-trans isomerase FKBP1A	target
Pimecrolimus	Serine/threonine-protein kinase mTOR	target
Pimecrolimus	Cytochrome P450 3A4	enzyme
Grepafloxacin	DNA gyrase subunit A	target
Grepafloxacin	DNA topoisomerase 4 subunit A	target
Grepafloxacin	Cytochrome P450 3A4	enzyme
Grepafloxacin	Cytochrome P450 1A2	enzyme
Grepafloxacin	Solute carrier family 22 member 2	transporter
Grepafloxacin	Solute carrier family 22 member 5	transporter
Grepafloxacin	Canalicular multispecific organic anion transporter 1	transporter
Grepafloxacin	P-glycoprotein 1	transporter
Grepafloxacin	Multidrug resistance-associated protein 1	transporter
Grepafloxacin	Solute carrier family 22 member 6	transporter
Dexrazoxane	DNA topoisomerase 2-alpha	target
Dexrazoxane	DNA topoisomerase 2-beta	target
Tacrine	Acetylcholinesterase	target
Tacrine	Cytochrome P450 1A2	enzyme
Tacrine	Cholinesterase	target
Tacrine	P-glycoprotein 1	transporter
Tacrine	Liver carboxylesterase 1	target
Valrubicin	DNA topoisomerase 2-alpha	target
Valrubicin	DNA	target
Sorafenib	Serine/threonine-protein kinase B-raf	target
Sorafenib	Receptor-type tyrosine-protein kinase FLT3	target
Sorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
Sorafenib	Vascular endothelial growth factor receptor 3	target
Sorafenib	Platelet-derived growth factor receptor beta	target
Sorafenib	Mast/stem cell growth factor receptor Kit	target
Sorafenib	Vascular endothelial growth factor receptor 2	target
Sorafenib	Cytochrome P450 3A4	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-9	enzyme
Sorafenib	Cytochrome P450 2B6	enzyme
Sorafenib	Cytochrome P450 2C8	enzyme
Sorafenib	Cytochrome P450 3A5	enzyme
Sorafenib	Cytochrome P450 3A7	enzyme
Sorafenib	Cytochrome P450 2C9	enzyme
Sorafenib	Multidrug resistance-associated protein 4	transporter
Sorafenib	P-glycoprotein 1	transporter
Sorafenib	Canalicular multispecific organic anion transporter 1	transporter
Sorafenib	ATP-binding cassette sub-family G member 2	transporter
Sorafenib	Cytochrome P450 1A2	enzyme
Sorafenib	Cytochrome P450 2C19	enzyme
Sorafenib	Cytochrome P450 2D6	enzyme
Sorafenib	UDP-glucuronosyltransferase 1-1	enzyme
Sorafenib	RalA-binding protein 1	transporter
Sorafenib	Fibroblast growth factor receptor 1	target
Sorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Sorafenib	Vascular endothelial growth factor receptor 1	target
Sorafenib	Solute carrier organic anion transporter family member 1B1	transporter
Cerivastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Cerivastatin	Cytochrome P450 2C8	enzyme
Cerivastatin	Cytochrome P450 3A4	enzyme
Cerivastatin	Cytochrome P450 2D6	enzyme
Cerivastatin	Cytochrome P450 2C9	enzyme
Cerivastatin	Cytochrome P450 3A5	enzyme
Cerivastatin	Cytochrome P450 3A7	enzyme
Cerivastatin	P-glycoprotein 1	transporter
Cerivastatin	Canalicular multispecific organic anion transporter 1	transporter
Cerivastatin	ATP-binding cassette sub-family G member 2	transporter
Cerivastatin	Solute carrier organic anion transporter family member 1B1	transporter
Cerivastatin	Cytochrome P450 2B6	enzyme
Cerivastatin	UDP-glucuronosyltransferase 1-1	enzyme
Cerivastatin	Bile salt export pump	transporter
Teniposide	DNA topoisomerase 2-alpha	target
Teniposide	Cytochrome P450 2C19	enzyme
Teniposide	Cytochrome P450 2C9	enzyme
Teniposide	Cytochrome P450 3A4	enzyme
Teniposide	Multidrug resistance-associated protein 6	transporter
Teniposide	ATP-binding cassette sub-family G member 2	transporter
Teniposide	Cytochrome P450 3A5	enzyme
Epirubicin	DNA topoisomerase 2-alpha	target
Epirubicin	DNA	target
Epirubicin	Multidrug resistance-associated protein 1	transporter
Epirubicin	UDP-glucuronosyltransferase 2B7	enzyme
Epirubicin	Cytosolic phospholipase A2	enzyme
Tenoxicam	Prostaglandin G/H synthase 1	target
Tenoxicam	Prostaglandin G/H synthase 2	target
Tenoxicam	Cytochrome P450 2C9	enzyme
Tenoxicam	Solute carrier family 22 member 8	transporter
Rimantadine	Matrix protein 2	target
Pefloxacin	DNA gyrase subunit A	target
Pefloxacin	DNA topoisomerase 4 subunit A	target
Pefloxacin	DNA topoisomerase 2-alpha	target
Pefloxacin	Cytochrome P450 1A2	enzyme
Pefloxacin	DNA topoisomerase 1	target
Tolmetin	Prostaglandin G/H synthase 1	target
Tolmetin	Prostaglandin G/H synthase 2	target
Tolmetin	Solute carrier family 22 member 6	transporter
Tolmetin	Tryptophan 2,3-dioxygenase	enzyme
Tolmetin	Myeloperoxidase	enzyme
Tolmetin	Serum albumin	carrier
Foscarnet	DNA polymerase catalytic subunit	target
Foscarnet	DNA polymerase catalytic subunit	target
Foscarnet	Solute carrier family 22 member 6	transporter
Foscarnet	Monocarboxylate transporter 1	transporter
Erlotinib	Epidermal growth factor receptor	target
Erlotinib	Cytochrome P450 3A4	enzyme
Erlotinib	ATP-binding cassette sub-family G member 2	transporter
Erlotinib	P-glycoprotein 1	transporter
Erlotinib	Nuclear receptor subfamily 1 group I member 2	target
Erlotinib	Cytochrome P450 3A5	enzyme
Erlotinib	Cytochrome P450 1A1	enzyme
Erlotinib	Cytochrome P450 1A2	enzyme
Erlotinib	Cytochrome P450 1B1	enzyme
Erlotinib	Cytochrome P450 2D6	enzyme
Erlotinib	Cytochrome P450 2C8	enzyme
Erlotinib	UDP-glucuronosyltransferase 1-1	enzyme
Erlotinib	Serum albumin	carrier
Erlotinib	Alpha-1-acid glycoprotein 1	carrier
Erlotinib	Solute carrier organic anion transporter family member 2B1	transporter
Erlotinib	Epidermal growth factor receptor	enzyme
Rofecoxib	Prostaglandin G/H synthase 2	target
Rofecoxib	Elastin	target
Rofecoxib	Cytochrome P450 3A4	enzyme
Rofecoxib	Cytochrome P450 1A2	enzyme
Rofecoxib	Multidrug resistance-associated protein 4	transporter
Rofecoxib	Prostaglandin G/H synthase 1	enzyme
Rofecoxib	Cytochrome P450 2C8	enzyme
Rofecoxib	Cytochrome P450 2C9	enzyme
Pentostatin	Adenosine deaminase	target
Piroxicam	Prostaglandin G/H synthase 1	target
Piroxicam	Prostaglandin G/H synthase 2	target
Piroxicam	Serum albumin	carrier
Piroxicam	Cytochrome P450 2C9	enzyme
Piroxicam	Solute carrier family 22 member 6	transporter
Piroxicam	Solute carrier family 22 member 8	transporter
Piroxicam	Solute carrier family 22 member 11	transporter
Piroxicam	Cytochrome P450 2C8	enzyme
Piroxicam	Solute carrier organic anion transporter family member 2B1	transporter
Tigecycline	30S ribosomal protein S9	target
Tigecycline	16S ribosomal RNA	target
Tigecycline	30S ribosomal protein S14	target
Tigecycline	30S ribosomal protein S13	target
Tigecycline	30S ribosomal protein S19	target
Tigecycline	30S ribosomal protein S12	target
Fenoprofen	Prostaglandin G/H synthase 1	target
Fenoprofen	Prostaglandin G/H synthase 2	target
Fenoprofen	Serum albumin	carrier
Fenoprofen	Peroxisome proliferator-activated receptor alpha	target
Fenoprofen	Peroxisome proliferator-activated receptor gamma	target
Valdecoxib	Prostaglandin G/H synthase 2	target
Valdecoxib	Cytochrome P450 2C9	enzyme
Valdecoxib	Cytochrome P450 3A4	enzyme
Valdecoxib	UDP-glucuronosyltransferase 1-9	enzyme
Valdecoxib	Carbonic anhydrase 2	target
Valdecoxib	Carbonic anhydrase 3	target
Sulindac	Prostaglandin G/H synthase 2	target
Sulindac	Aldose reductase	target
Sulindac	Prostaglandin G/H synthase 1	target
Sulindac	Mitogen-activated protein kinase 3	target
Sulindac	Peroxisome proliferator-activated receptor delta	target
Sulindac	Prostaglandin D2 receptor 2	target
Sulindac	Serum albumin	carrier
Sulindac	Solute carrier family 22 member 6	transporter
Sulindac	Cytochrome P450 1A1	enzyme
Sulindac	Aldo-keto reductase family 1 member B10	target
Furazolidone	DNA	target
Furazolidone	Amine oxidase [flavin-containing] B	enzyme
Furazolidone	Amine oxidase [flavin-containing] A	enzyme
Stavudine	Solute carrier family 22 member 6	transporter
Stavudine	Reverse transcriptase/RNaseH	target
Stavudine	Sodium/nucleoside cotransporter 1	transporter
Stavudine	Serum albumin	carrier
Dyphylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Dyphylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Dyphylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Dyphylline	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Dyphylline	Adenosine receptor A1	target
Dyphylline	Adenosine receptor A2a	target
Trovafloxacin	DNA gyrase subunit A	target
Trovafloxacin	DNA topoisomerase 4 subunit A	target
Trovafloxacin	DNA topoisomerase 2-alpha	target
Trovafloxacin	Cytochrome P450 1A2	enzyme
Lamivudine	DNA	target
Lamivudine	Protein P	target
Lamivudine	Multidrug resistance-associated protein 1	transporter
Lamivudine	Solute carrier family 22 member 6	transporter
Lamivudine	ATP-binding cassette sub-family G member 2	transporter
Lamivudine	Reverse transcriptase/RNaseH	target
Lamivudine	Solute carrier family 22 member 1	transporter
Lamivudine	Solute carrier family 22 member 2	transporter
Lamivudine	Solute carrier family 22 member 3	transporter
Lamivudine	Deoxycytidine kinase	enzyme
Lamivudine	UMP-CMP kinase	enzyme
Lamivudine	Phosphoglycerate kinase 1	enzyme
Lamivudine	Nucleoside diphosphate kinase A	enzyme
Lamivudine	Nucleoside diphosphate kinase B	enzyme
Lamivudine	Choline-phosphate cytidylyltransferase A	enzyme
Lamivudine	Ethanolamine-phosphate cytidylyltransferase	enzyme
Lamivudine	P-glycoprotein 1	transporter
Lamivudine	Multidrug resistance-associated protein 4	transporter
Lamivudine	Canalicular multispecific organic anion transporter 2	transporter
Lamivudine	Canalicular multispecific organic anion transporter 1	transporter
Lamivudine	5'(3')-deoxyribonucleotidase, cytosolic type	enzyme
Lamivudine	Serum albumin	carrier
Diethylcarbamazine	Arachidonate 5-lipoxygenase	target
Diethylcarbamazine	Prostaglandin G/H synthase 1	target
Diethylcarbamazine	Cholinesterase	enzyme
Flurbiprofen	Prostaglandin G/H synthase 2	target
Flurbiprofen	Prostaglandin G/H synthase 1	target
Flurbiprofen	Cytochrome P450 2C9	enzyme
Flurbiprofen	Serum albumin	carrier
Flurbiprofen	Multidrug resistance-associated protein 4	transporter
Flurbiprofen	Solute carrier family 22 member 6	transporter
Flurbiprofen	UDP-glucuronosyltransferase 2B7	enzyme
Flurbiprofen	UDP-glucuronosyltransferase 1-1	enzyme
Flurbiprofen	UDP-glucuronosyltransferase 1-3	enzyme
Flurbiprofen	UDP-glucuronosyltransferase 1-9	enzyme
Flurbiprofen	UDP-glucuronosyltransferase 2B4	enzyme
Adefovir dipivoxil	DNA polymerase/reverse transcriptase	target
Adefovir dipivoxil	Solute carrier family 22 member 6	transporter
Adefovir dipivoxil	Multidrug resistance-associated protein 4	transporter
Adefovir dipivoxil	Multidrug resistance-associated protein 5	transporter
Adefovir dipivoxil	Solute carrier family 22 member 3	transporter
Adefovir dipivoxil	Adenylate kinase 2, mitochondrial	enzyme
Adefovir dipivoxil	Adenylate kinase 4, mitochondrial	enzyme
Adefovir dipivoxil	Nucleoside diphosphate kinase A	enzyme
Adefovir dipivoxil	Nucleoside diphosphate kinase B	enzyme
Esomeprazole	Potassium-transporting ATPase alpha chain 1	target
Esomeprazole	Cytochrome P450 2C19	enzyme
Esomeprazole	Cytochrome P450 3A4	enzyme
Esomeprazole	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	target
Esomeprazole	P-glycoprotein 1	transporter
Esomeprazole	Solute carrier family 22 member 8	transporter
Zileuton	Arachidonate 5-lipoxygenase	target
Zileuton	Cytochrome P450 2C9	enzyme
Zileuton	Cytochrome P450 1A2	enzyme
Zileuton	Cytochrome P450 3A4	enzyme
Zileuton	Prostaglandin G/H synthase 1	enzyme
Zileuton	UDP-glucuronosyltransferase 1-9	enzyme
Zileuton	Serum albumin	carrier
Etodolac	Prostaglandin G/H synthase 1	target
Etodolac	Prostaglandin G/H synthase 2	target
Etodolac	Cytochrome P450 2C9	enzyme
Etodolac	UDP-glucuronosyltransferase 1-9	enzyme
Etodolac	Retinoic acid receptor RXR-alpha	target
Etodolac	Serum albumin	carrier
Etodolac	Solute carrier family 22 member 6	transporter
Etodolac	UDP-glucuronosyltransferase 1-3	enzyme
Etodolac	UDP-glucuronosyltransferase 1-10	enzyme
Etodolac	UDP-glucuronosyltransferase 2B7	enzyme
Tranylcypromine	Amine oxidase [flavin-containing] B	target
Tranylcypromine	Amine oxidase [flavin-containing] A	target
Tranylcypromine	Cytochrome P450 2C19	enzyme
Tranylcypromine	Cytochrome P450 2A6	enzyme
Tranylcypromine	Cytochrome P450 2D6	enzyme
Tranylcypromine	Cytochrome P450 1A2	enzyme
Tranylcypromine	Cytochrome P450 2C9	enzyme
Tranylcypromine	Cytochrome P450 3A4	enzyme
Tetracycline	16S ribosomal RNA	target
Tetracycline	Major prion protein	target
Tetracycline	Serum albumin	carrier
Tetracycline	Cytochrome P450 3A4	enzyme
Tetracycline	Solute carrier family 22 member 6	transporter
Tetracycline	Solute carrier family 22 member 8	transporter
Tetracycline	Solute carrier family 22 member 11	transporter
Tetracycline	Solute carrier family 22 member 7	transporter
Tetracycline	30S ribosomal protein S3	target
Tetracycline	30S ribosomal protein S8	target
Tetracycline	30S ribosomal protein S19	target
Tetracycline	30S ribosomal protein S14	target
Tetracycline	30S ribosomal protein S7	target
Tetracycline	Multidrug translocase MdfA	target
Tetracycline	Protein-arginine deiminase type-4	target
Tetracycline	Solute carrier organic anion transporter family member 2B1	transporter
Malathion	Cholinesterase	target
Malathion	Cytochrome P450 1A2	enzyme
Malathion	Cytochrome P450 2B6	enzyme
Etoposide	DNA topoisomerase 2-alpha	target
Etoposide	Cytochrome P450 3A4	enzyme
Etoposide	Canalicular multispecific organic anion transporter 2	transporter
Etoposide	Multidrug resistance-associated protein 6	transporter
Etoposide	P-glycoprotein 1	transporter
Etoposide	Multidrug resistance-associated protein 1	transporter
Etoposide	Multidrug resistance-associated protein 7	transporter
Etoposide	Canalicular multispecific organic anion transporter 1	transporter
Etoposide	ATP-binding cassette sub-family G member 2	transporter
Etoposide	Cytochrome P450 1A2	enzyme
Etoposide	Cytochrome P450 2E1	enzyme
Etoposide	Cytochrome P450 3A5	enzyme
Etoposide	UDP-glucuronosyltransferase 1-1	enzyme
Etoposide	DNA topoisomerase 2-beta	target
Etoposide	Glutathione S-transferase theta-1	enzyme
Etoposide	Glutathione S-transferase P	enzyme
Etoposide	Prostaglandin G/H synthase 2	enzyme
Etoposide	Prostaglandin G/H synthase 1	enzyme
Phenelzine	Membrane primary amine oxidase	target
Phenelzine	Amine oxidase [flavin-containing] B	target
Phenelzine	Amine oxidase [flavin-containing] A	target
Phenelzine	Amine oxidase [flavin-containing] A	enzyme
Phenelzine	Amine oxidase [flavin-containing] B	enzyme
Phenelzine	Cytochrome P450 2E1	enzyme
Phenelzine	4-aminobutyrate aminotransferase, mitochondrial	target
Phenelzine	Glutamic acid decarboxylase	target
Phenelzine	Alanine aminotransferase 1	target
Phenelzine	Alanine aminotransferase 2	target
Phenelzine	Cytochrome P450 2C19	enzyme
Phenelzine	Cytochrome P450 2C8	enzyme
Phenelzine	Cytochrome P450 3A4	enzyme
Phenelzine	Cytochrome P450 3A5	enzyme
Phenelzine	Cytochrome P450 3A7	enzyme
Phenelzine	Cytochrome P450 2D6	enzyme
Phenelzine	Cytochrome P450 3A Subfamily	enzyme
Gentamicin	30S ribosomal protein S12	target
Gentamicin	16S ribosomal RNA	target
Gentamicin	NH(3)-dependent NAD(+) synthetase	target
Gentamicin	Dihydrofolate reductase	target
Gentamicin	23S ribosomal RNA	target
Gentamicin	Bacterial outer membrane	target
Gentamicin	Cytoplasmic membrane	target
Gentamicin	Low-density lipoprotein receptor-related protein 2	transporter
Gentamicin	Solute carrier family 22 member 2	transporter
Gentamicin	Canalicular multispecific organic anion transporter 1	transporter
Disulfiram	Aldehyde dehydrogenase, mitochondrial	target
Disulfiram	Cytochrome P450 2E1	enzyme
Disulfiram	Dopamine beta-hydroxylase	target
Disulfiram	Cytochrome P450 3A4	enzyme
Disulfiram	Cytochrome P450 3A5	enzyme
Disulfiram	Bile salt export pump	transporter
Cinoxacin	DNA	target
Cinoxacin	DNA gyrase subunit A	target
Cinoxacin	Solute carrier family 22 member 6	transporter
Cinoxacin	Cytochrome P450 1A2	enzyme
Diflunisal	Prostaglandin G/H synthase 1	target
Diflunisal	Prostaglandin G/H synthase 2	target
Diflunisal	Transthyretin	carrier
Diflunisal	Serum albumin	carrier
Diflunisal	Solute carrier family 22 member 6	transporter
Diflunisal	UDP-glucuronosyltransferase 1-8	enzyme
Diflunisal	UDP-glucuronosyltransferase 1-9	enzyme
Vardenafil	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Vardenafil	Cytochrome P450 3A4	enzyme
Vardenafil	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	target
Vardenafil	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	target
Vardenafil	Cytochrome P450 3A5	enzyme
Vardenafil	P-glycoprotein 1	transporter
Vardenafil	Cytochrome P450 2C9	enzyme
Vardenafil	Cytochrome P450 2C8	enzyme
Vardenafil	Cytochrome P450 2C19	enzyme
Vardenafil	Cytochrome P450 2D6	enzyme
Didanosine	Solute carrier family 22 member 6	transporter
Didanosine	Purine nucleoside phosphorylase	target
Didanosine	Reverse transcriptase/RNaseH	target
Didanosine	Equilibrative nucleoside transporter 1	transporter
Didanosine	Equilibrative nucleoside transporter 2	transporter
Didanosine	Serum albumin	carrier
Levosimendan	Troponin C, slow skeletal and cardiac muscles	target
Levosimendan	ATP-sensitive inward rectifier potassium channel 11	target
Levosimendan	ATP-sensitive inward rectifier potassium channel 8	target
Levosimendan	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Salicylic acid	Serum albumin	carrier
Salicylic acid	Prostaglandin G/H synthase 1	target
Salicylic acid	Prostaglandin G/H synthase 2	target
Salicylic acid	Aldo-keto reductase family 1 member C1	target
Salicylic acid	Solute carrier family 22 member 6	transporter
Salicylic acid	Solute carrier family 22 member 10	transporter
Salicylic acid	Solute carrier family 22 member 8	transporter
Salicylic acid	Solute carrier family 22 member 11	transporter
Salicylic acid	Solute carrier organic anion transporter family member 2B1	transporter
Salicylic acid	Monocarboxylate transporter 1	transporter
Salicylic acid	Solute carrier family 22 member 7	transporter
Salicylic acid	Cytochrome P450 2C9	enzyme
Meclofenamic acid	Prostaglandin G/H synthase 1	target
Meclofenamic acid	Prostaglandin G/H synthase 2	target
Meclofenamic acid	Arachidonate 5-lipoxygenase	target
Meclofenamic acid	Solute carrier family 22 member 6	transporter
Meclofenamic acid	Solute carrier organic anion transporter family member 1C1	transporter
Meclofenamic acid	Potassium voltage-gated channel subfamily KQT member 2	target
Meclofenamic acid	Potassium voltage-gated channel subfamily KQT member 3	target
Meclofenamic acid	Thyroxine-binding globulin	carrier
Zalcitabine	Deoxycytidine kinase	enzyme
Zalcitabine	Solute carrier family 22 member 6	transporter
Zalcitabine	Solute carrier family 22 member 7	transporter
Zalcitabine	Reverse transcriptase/RNaseH	target
Zalcitabine	Equilibrative nucleoside transporter 1	transporter
Zalcitabine	Equilibrative nucleoside transporter 2	transporter
Zalcitabine	Serum albumin	carrier
Netilmicin	30S ribosomal protein S12	target
Netilmicin	16S ribosomal RNA	target
Dactinomycin	DNA	target
Dactinomycin	Solute carrier family 22 member 5	transporter
Dactinomycin	P-glycoprotein 1	transporter
Dactinomycin	Multidrug resistance-associated protein 6	transporter
Dactinomycin	Multidrug resistance-associated protein 1	transporter
Dactinomycin	ATP-binding cassette sub-family G member 2	transporter
Dactinomycin	DNA topoisomerase 2	target
Dactinomycin	DNA topoisomerase 1	target
Dipyridamole	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	target
Dipyridamole	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Dipyridamole	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Dipyridamole	Adenosine deaminase	target
Dipyridamole	Multidrug resistance-associated protein 4	transporter
Dipyridamole	Multidrug resistance-associated protein 5	transporter
Dipyridamole	P-glycoprotein 1	transporter
Dipyridamole	Calcipressin-1	target
Dipyridamole	Alpha-1-acid glycoprotein 1	target
Dipyridamole	Solute carrier organic anion transporter family member 1B1	transporter
Dipyridamole	Solute carrier organic anion transporter family member 1B3	transporter
Dipyridamole	Solute carrier organic anion transporter family member 2B1	transporter
Dipyridamole	Bile salt export pump	transporter
Physostigmine	Acetylcholinesterase	target
Physostigmine	Neuronal acetylcholine receptor subunit alpha-4	target
Physostigmine	Neuronal acetylcholine receptor subunit beta-2	target
Rivastigmine	Acetylcholinesterase	target
Rivastigmine	Cholinesterase	target
Oxaprozin	Prostaglandin G/H synthase 2	target
Oxaprozin	Prostaglandin G/H synthase 1	target
Tioconazole	Lanosterol 14-alpha demethylase	target
Tioconazole	Cytochrome P450 19A1	enzyme
Tioconazole	Cytochrome P450 2C19	enzyme
Tioconazole	Cytochrome P450 2E1	enzyme
Tioconazole	Cytochrome P450 3A4	enzyme
Tioconazole	Cytochrome P450 51	target
Ketoprofen	Prostaglandin G/H synthase 1	target
Ketoprofen	Prostaglandin G/H synthase 2	target
Ketoprofen	C-X-C chemokine receptor type 1	target
Ketoprofen	Serum albumin	carrier
Ketoprofen	Multidrug resistance-associated protein 4	transporter
Ketoprofen	Solute carrier organic anion transporter family member 1A2	transporter
Ketoprofen	Solute carrier family 22 member 6	transporter
Ketoprofen	Solute carrier family 22 member 8	transporter
Ketoprofen	Solute carrier family 22 member 11	transporter
Ketoprofen	Solute carrier family 22 member 7	transporter
Ketoprofen	Cytochrome P450 2C9	enzyme
Ketoprofen	Cytochrome P450 2C8	enzyme
Ketoprofen	UDP-glucuronosyltransferase 1-1	enzyme
Mercaptopurine	Thiopurine S-methyltransferase	enzyme
Mercaptopurine	Xanthine dehydrogenase/oxidase	enzyme
Mercaptopurine	Hypoxanthine-guanine phosphoribosyltransferase	target
Mercaptopurine	Solute carrier family 22 member 8	transporter
Mercaptopurine	Multidrug resistance-associated protein 4	transporter
Mercaptopurine	Multidrug resistance-associated protein 5	transporter
Mercaptopurine	Sodium/nucleoside cotransporter 2	transporter
Mercaptopurine	Solute carrier family 28 member 3	transporter
Mercaptopurine	Equilibrative nucleoside transporter 1	transporter
Mercaptopurine	Equilibrative nucleoside transporter 2	transporter
Mercaptopurine	Aldehyde oxidase	enzyme
Mercaptopurine	Amidophosphoribosyltransferase	target
Mercaptopurine	Inosine-5'-monophosphate dehydrogenase	target
Selegiline	Amine oxidase [flavin-containing] B	target
Selegiline	Cytochrome P450 2B6	enzyme
Selegiline	Amine oxidase [flavin-containing] A	target
Selegiline	Cytochrome P450 2A6	enzyme
Selegiline	Cytochrome P450 3A4	enzyme
Selegiline	P-glycoprotein 1	transporter
Selegiline	Cytochrome P450 1A2	enzyme
Selegiline	Cytochrome P450 2C19	enzyme
Selegiline	Cytochrome P450 2C8	enzyme
Selegiline	Cytochrome P450 2C9	enzyme
Selegiline	Cytochrome P450 2D6	enzyme
Rifampicin	DNA-directed RNA polymerase subunit beta	target
Rifampicin	Nuclear receptor subfamily 1 group I member 2	target
Rifampicin	Cytochrome P450 3A4	enzyme
Rifampicin	Cytochrome P450 1A2	enzyme
Rifampicin	Cytochrome P450 2C8	enzyme
Rifampicin	UDP-glucuronosyltransferase 1-1	enzyme
Rifampicin	Cytochrome P450 2C9	enzyme
Rifampicin	Cytochrome P450 2B6	enzyme
Rifampicin	Cytochrome P450 2C19	enzyme
Rifampicin	Canalicular multispecific organic anion transporter 2	transporter
Rifampicin	Multidrug resistance-associated protein 5	transporter
Rifampicin	P-glycoprotein 1	transporter
Rifampicin	Canalicular multispecific organic anion transporter 1	transporter
Rifampicin	Solute carrier organic anion transporter family member 2B1	transporter
Rifampicin	Bile salt export pump	transporter
Rifampicin	Multidrug resistance-associated protein 1	transporter
Rifampicin	Solute carrier organic anion transporter family member 1A2	transporter
Rifampicin	Solute carrier organic anion transporter family member 1B3	transporter
Rifampicin	Solute carrier family 22 member 7	transporter
Rifampicin	Solute carrier organic anion transporter family member 1B1	transporter
Rifampicin	Cytochrome P450 2A6	enzyme
Rifampicin	Cytochrome P450 2E1	enzyme
Rifampicin	Cytochrome P450 3A43	enzyme
Rifampicin	Cytochrome P450 3A7	enzyme
Rifampicin	Solute carrier family 22 member 6	transporter
Rifampicin	Solute carrier family 22 member 8	transporter
Rifampicin	UDP-glucuronosyltransferase 1-9	enzyme
Rifampicin	Cytochrome P450 3A5	enzyme
Rifampicin	Serum albumin	carrier
Rifampicin	alpha1-acid glycoprotein	carrier
Abacavir	Alcohol dehydrogenase 6	enzyme
Abacavir	UDP-glucuronosyltransferase 1-1	enzyme
Abacavir	Reverse transcriptase/RNaseH	target
Abacavir	Adenosine kinase	enzyme
Abacavir	HLA class I histocompatibility antigen, B-57 alpha chain	target
Echothiophate	Cholinesterase	target
Echothiophate	Serum albumin	carrier
Rosuvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Rosuvastatin	Cytochrome P450 2C9	enzyme
Rosuvastatin	Multidrug resistance-associated protein 4	transporter
Rosuvastatin	Solute carrier organic anion transporter family member 1A2	transporter
Rosuvastatin	Solute carrier organic anion transporter family member 1B3	transporter
Rosuvastatin	Solute carrier organic anion transporter family member 2B1	transporter
Rosuvastatin	Cystine/glutamate transporter	transporter
Rosuvastatin	Solute carrier organic anion transporter family member 1B1	transporter
Rosuvastatin	Bile salt export pump	transporter
Rosuvastatin	ATP-binding cassette sub-family G member 2	transporter
Rosuvastatin	Serum albumin	carrier
Rosuvastatin	Canalicular multispecific organic anion transporter 1	transporter
Rosuvastatin	Solute carrier family 22 member 8	transporter
Rosuvastatin	Sodium/bile acid cotransporter	transporter
Rosuvastatin	Integrin alpha-L	target
Papaverine	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Papaverine	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	target
Papaverine	Phosphodiesterase enzymes	target
Ambenonium	Acetylcholinesterase	target
Ambenonium	Cholinesterase	enzyme
Rabeprazole	Potassium-transporting ATPase alpha chain 1	target
Rabeprazole	Cytochrome P450 3A4	enzyme
Rabeprazole	Cytochrome P450 2C19	enzyme
Rabeprazole	ATP-binding cassette sub-family G member 2	transporter
Rabeprazole	Cytochrome P450 1A1	enzyme
Rabeprazole	Cytochrome P450 1A2	enzyme
Rabeprazole	Cytochrome P450 2C9	enzyme
Rabeprazole	Cytochrome P450 2D6	enzyme
Rabeprazole	Cytochrome P450 2C8	enzyme
Diclofenamide	Carbonic anhydrase 1	target
Diclofenamide	Carbonic anhydrase 4	target
Diclofenamide	Carbonic anhydrase 2	target
Diclofenamide	Carbonic anhydrase 7	target
Diclofenamide	Carbonic anhydrase 3	target
Cilostazol	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Cilostazol	Cytochrome P450 2C19	enzyme
Cilostazol	Cytochrome P450 3A4	enzyme
Cilostazol	Cytochrome P450 3A5	enzyme
Cilostazol	Cytochrome P450 3A7	enzyme
Cilostazol	Cytochrome P450 1A2	enzyme
Cilostazol	Cytochrome P450 2D6	enzyme
Moclobemide	Amine oxidase [flavin-containing] A	target
Moclobemide	Cytochrome P450 2C19	enzyme
Moclobemide	Cytochrome P450 2D6	enzyme
Moclobemide	Amine oxidase [flavin-containing] A	enzyme
Moclobemide	Amine oxidase [flavin-containing] B	enzyme
Moclobemide	Cytochrome P450 2C9	enzyme
Moclobemide	Monoamine oxidase	target
Moclobemide	Amine oxidase [flavin-containing] B	target
Idarubicin	DNA topoisomerase 2-alpha	target
Idarubicin	DNA	target
Idarubicin	Multidrug resistance-associated protein 1	transporter
Idarubicin	Cytochrome P450 2C9	enzyme
Idarubicin	Cytochrome P450 2D6	enzyme
Mitoxantrone	DNA topoisomerase 2-alpha	target
Mitoxantrone	Cytochrome P450 2E1	enzyme
Mitoxantrone	P-glycoprotein 1	transporter
Mitoxantrone	Multidrug resistance-associated protein 1	transporter
Mitoxantrone	ATP-binding cassette sub-family G member 2	transporter
Mitoxantrone	DNA	target
Mitoxantrone	Cytochrome P450 1B1	enzyme
Mitoxantrone	Cytochrome P450 3A4	enzyme
Sparfloxacin	DNA gyrase subunit A	target
Sparfloxacin	DNA topoisomerase 4 subunit A	target
Sparfloxacin	DNA topoisomerase 2-alpha	target
Sparfloxacin	Solute carrier family 22 member 5	transporter
Sparfloxacin	Canalicular multispecific organic anion transporter 1	transporter
Sparfloxacin	P-glycoprotein 1	transporter
Sparfloxacin	Cytochrome P450 1A2	enzyme
Aminophylline	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Aminophylline	Adenosine receptor A3	target
Aminophylline	Adenosine receptor A1	target
Aminophylline	Cytochrome P450 1A2	enzyme
Aminophylline	Cytochrome P450 2E1	enzyme
Aminophylline	Cytochrome P450 3A4	enzyme
Aminophylline	Histone deacetylase 2	target
Isocarboxazid	Amine oxidase [flavin-containing] A	target
Isocarboxazid	Amine oxidase [flavin-containing] B	target
Telbivudine	Protein P	target
Telbivudine	DNA	target
Lumiracoxib	Prostaglandin G/H synthase 2	target
Lumiracoxib	Prostaglandin G/H synthase 1	target
Lumiracoxib	Cytochrome P450 2C9	enzyme
Lumiracoxib	Cytochrome P450 2C19	enzyme
Lumiracoxib	UDP-glucuronosyltransferase 1-9	enzyme
Lumiracoxib	Cytochrome P450 1A2	enzyme
Rasagiline	Apoptosis regulator Bcl-2	target
Rasagiline	Amine oxidase [flavin-containing] B	target
Rasagiline	Cytochrome P450 1A2	enzyme
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1G	target
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1H	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1C	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-1	target
Mibefradil	Cytochrome P450 3A4	enzyme
Mibefradil	Cytochrome P450 1A2	enzyme
Mibefradil	Cytochrome P450 2D6	enzyme
Mibefradil	Cytochrome P450 3A5	enzyme
Mibefradil	Cytochrome P450 3A7	enzyme
Mibefradil	P-glycoprotein 1	transporter
Mibefradil	Voltage-dependent T-type calcium channel subunit alpha-1I	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1S	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1F	target
Mibefradil	Voltage-dependent L-type calcium channel subunit alpha-1D	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-2	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-3	target
Mibefradil	Voltage-dependent L-type calcium channel subunit beta-4	target
Mibefradil	Cytochrome P450 11B1, mitochondrial	enzyme
Mibefradil	Cytochrome P450 11B2, mitochondrial	enzyme
Magnesium salicylate	Serum albumin	carrier
Magnesium salicylate	Prostaglandin G/H synthase 1	target
Magnesium salicylate	Prostaglandin G/H synthase 2	target
Neostigmine	Acetylcholinesterase	target
Neostigmine	Cholinesterase	enzyme
Temafloxacin	DNA gyrase subunit A	target
Temafloxacin	DNA topoisomerase 4 subunit A	target
Temafloxacin	Cytochrome P450 1A2	enzyme
Amrinone	Tumor necrosis factor	target
Amrinone	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Amrinone	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	target
Amrinone	cAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4)	target
Amrinone	cAMP-specific 3',5'-cyclic phosphodiesterase 3	target
Pargyline	Amine oxidase [flavin-containing] B	target
Pargyline	Amine oxidase [flavin-containing] A	target
Etoricoxib	Prostaglandin G/H synthase 2	target
Etoricoxib	Cytochrome P450 3A4	enzyme
Etoricoxib	Cytochrome P450 2C9	enzyme
Etoricoxib	Cytochrome P450 2D6	enzyme
Etoricoxib	Cytochrome P450 1A2	enzyme
Etoricoxib	Cytochrome P450 2C19	enzyme
Etoricoxib	Cytochrome P450 2E1	enzyme
Genistein	Estrogen receptor beta	target
Genistein	DNA topoisomerase 2-alpha	target
Genistein	Protein-tyrosine kinase 2-beta	target
Genistein	P-glycoprotein 1	transporter
Genistein	Multidrug resistance-associated protein 1	transporter
Genistein	ATP-binding cassette sub-family G member 2	transporter
Genistein	Cytochrome P450 1A2	enzyme
Genistein	Nuclear receptor coactivator 1	target
Genistein	Estrogen receptor alpha	target
Genistein	Nuclear receptor coactivator 2	target
Genistein	Transthyretin	carrier
Genistein	Steroid hormone receptor ERR2	target
Genistein	Steroid hormone receptor ERR1	target
Genistein	Nuclear receptor subfamily 1 group I member 2	target
Genistein	RAC-alpha serine/threonine-protein kinase	target
Genistein	G-protein coupled estrogen receptor 1	target
Genistein	Cytochrome P450 1B1	target
Genistein	Sex hormone-binding globulin	target
Genistein	Cytochrome P450 1A1	enzyme
Genistein	Solute carrier organic anion transporter family member 1B1	transporter
Genistein	Solute carrier organic anion transporter family member 2B1	transporter
Genistein	Cytochrome P450 2C8	enzyme
Genistein	Cytochrome P450 2C9	enzyme
Genistein	Cytochrome P450 3A1	enzyme
Genistein	Cytochrome P450 3A2	enzyme
Genistein	Cytochrome P450 3A4	enzyme
Genistein	Cystic fibrosis transmembrane conductance regulator	target
(Rp)-cAMPS	cAMP-dependent protein kinase type I-alpha regulatory subunit	target
Piclamilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Piclamilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Piclamilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Piclamilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
7-Hydroxystaurosporine	3-phosphoinositide-dependent protein kinase 1	target
Rolipram	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Rolipram	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Rolipram	cAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4)	target
Vorinostat	Histone deacetylase 1	target
Vorinostat	Histone deacetylase 2	target
Vorinostat	Histone deacetylase 3	target
Vorinostat	Histone deacetylase 6	target
Vorinostat	Histone deacetylase 8	target
Vorinostat	Acetoin utilization protein	target
Vorinostat	Histone deacetylase	target
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide	Histone deacetylase 8	target
Zardaverine	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Arsanilic acid	Lysozyme C	target
3-Methoxybenzamide	Poly [ADP-ribose] polymerase 1	target
Alvocidib	Glycogen phosphorylase, muscle form	target
Alvocidib	Cyclin-dependent kinase 7	target
Alvocidib	Cyclin-dependent kinase 5	target
Alvocidib	Cyclin-dependent kinase 9	target
Alvocidib	Cyclin-dependent kinase 1	target
Alvocidib	Cyclin-dependent kinase 6	target
Alvocidib	Epidermal growth factor receptor	target
Alvocidib	Cyclin-dependent kinase 4	target
Alvocidib	Cyclin-dependent kinase 8	target
Alvocidib	Cyclin-dependent kinase 2	target
Alvocidib	ATP-binding cassette sub-family G member 2	transporter
Alvocidib	Glycogen phosphorylase, brain form	target
Alvocidib	Glycogen phosphorylase, liver form	target
Alvocidib	UDP-glucuronosyltransferase 1-1	enzyme
2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	Poly [ADP-ribose] polymerase 1	target
Picric acid	Pentaerythritol tetranitrate reductase	target
Piritrexim	Dihydrofolate reductase	target
Cilomilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Cilomilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Clorgiline	Amine oxidase [flavin-containing] A	target
Trichostatin A	Histone deacetylase 8	target
Trichostatin A	Acetoin utilization protein	target
Trichostatin A	Histone deacetylase 7	target
Trichostatin A	Caspase-8	target
Trichostatin A	Prostaglandin E2 Receptors	target
Trichostatin A	Tumor necrosis factor	target
3,4-Dichloroisocoumarin	Complement factor D	target
2,4-Dinitrophenol	Pentaerythritol tetranitrate reductase	target
Niflumic acid	Phospholipase A2	target
Niflumic acid	Chloride channel protein ClC-Ka	target
Niflumic acid	Monocarboxylate transporter 2	transporter
Niflumic acid	Monocarboxylate transporter 1	transporter
Niflumic acid	Prostaglandin G/H synthase 2	target
Niflumic acid	Prostaglandin G/H synthase 1	target
Niflumic acid	Cytosolic phospholipase A2	target
Niflumic acid	UDP-glucuronosyltransferase 1-9	target
Niflumic acid	UDP-glucuronosyltransferase 1-9	enzyme
Fleroxacin	DNA topoisomerase 2-alpha	target
Fleroxacin	DNA gyrase subunit A	target
Fleroxacin	DNA topoisomerase 4 subunit A	target
Camptothecin	DNA topoisomerase 1	target
Camptothecin	P-glycoprotein 1	transporter
Camptothecin	ATP-binding cassette sub-family G member 2	transporter
Camptothecin	Serum albumin	carrier
Licofelone	Arachidonate 5-lipoxygenase	target
Licofelone	Prostaglandin G/H synthase 2	target
Licofelone	Group IIE secretory phospholipase A2	target
Licofelone	Cytochrome P450 2C9	enzyme
Licofelone	Cytochrome P450 2C8	enzyme
Licofelone	Cytochrome P450 2J2	enzyme
Licofelone	UDP-glucuronosyltransferase 1-3	enzyme
Nimesulide	Prostaglandin G/H synthase 2	target
Nimesulide	Group IIE secretory phospholipase A2	target
Nimesulide	Lactotransferrin	target
Nimesulide	Cytochrome P450 3A4	enzyme
Iproniazid	Amine oxidase [flavin-containing] B	enzyme
Iproniazid	Cytochrome P450 2D6	enzyme
Iproniazid	Cytochrome P450 2C9	enzyme
Iproniazid	Amine oxidase [flavin-containing] A	enzyme
Nialamide	Amine oxidase [flavin-containing] B	target
Nialamide	Amine oxidase [flavin-containing] A	target
Nialamide	Catechol O-methyltransferase	target
Cediranib	Vascular endothelial growth factor receptor 2	target
Huperzine A	Acetylcholinesterase	target
Omacetaxine mepesuccinate	50S ribosomal protein L2	target
Omacetaxine mepesuccinate	60S ribosomal protein L3	target
Halofuginone	Collagen alpha-1(I) chain	target
Halofuginone	72 kDa type IV collagenase	target
Voglibose	Maltase-glucoamylase, intestinal	target
Vatalanib	Vascular endothelial growth factor receptor 1	target
Vatalanib	Vascular endothelial growth factor receptor 2	target
Vatalanib	Vascular endothelial growth factor receptor 3	target
Enoximone	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Phenserine	Acetylcholinesterase	target
Phenserine	Cholinesterase	target
Phenserine	Amyloid beta A4 protein	target
Ranpirnase	DNA	target
E-2012	Gamma-secretase subunit APH-1A	target
E-2012	Gamma-secretase subunit PEN-2	target
Ibudilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
Ibudilast	cGMP-inhibited 3',5'-cyclic phosphodiesterase A	target
Ibudilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	target
Ibudilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Ibudilast	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Tarenflurbil	NF-kappa-B essential modulator	target
SN-38	DNA topoisomerase 1	target
SN-38	Cytochrome P450 3A4	enzyme
Pelitinib	Epidermal growth factor receptor	target
Apremilast	Phosphodiesterase isozyme 4	target
Apremilast	Cytochrome P450 3A4	enzyme
Apremilast	Cytochrome P450 2A6	enzyme
Apremilast	Cytochrome P450 1A2	enzyme
Apremilast	P-glycoprotein 1	transporter
Varespladib methyl	Phospholipase A2, membrane associated	target
Varespladib methyl	Group 10 secretory phospholipase A2	target
AV-412	Epidermal growth factor receptor	target
AV-412	Receptor tyrosine-protein kinase erbB-2	target
Rubitecan	DNA topoisomerase 1	target
Garenoxacin	Cytochrome P450 1A2	enzyme
Romidepsin	Cytochrome P450 3A4	enzyme
Romidepsin	Cytochrome P450 3A5	enzyme
Romidepsin	P-glycoprotein 1	transporter
Romidepsin	Solute carrier organic anion transporter family member 1B3	transporter
Romidepsin	Cytochrome P450 1A1	enzyme
Romidepsin	Cytochrome P450 2B6	enzyme
Romidepsin	Cytochrome P450 2C19	enzyme
Romidepsin	Histone deacetylase 1	target
Romidepsin	Histone deacetylase 2	target
Romidepsin	Histone deacetylase 4	target
Romidepsin	Histone deacetylase 6	target
Romidepsin	Multidrug resistance-associated protein 1	target
Romidepsin	Bile salt export pump	transporter
Romidepsin	Solute carrier organic anion transporter family member 1B1	transporter
Romidepsin	Solute carrier family 22 member 6	transporter
Romidepsin	Solute carrier family 22 member 2	transporter
Romidepsin	Histone deacetylase	target
Seliciclib	Cyclin-dependent kinase 1	target
Seliciclib	Cyclin-dependent kinase 2	target
Seliciclib	Mitogen-activated protein kinase 3	target
Seliciclib	Mitogen-activated protein kinase 1	target
Seliciclib	Cyclin-dependent kinase 7	target
Seliciclib	Cyclin-dependent kinase 9	target
Seliciclib	Casein kinase I isoform epsilon	target
Seliciclib	Prostaglandin G/H synthase 2	enzyme
Elvucitabine	Reverse transcriptase/RNaseH	target
Exisulind	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
Exisulind	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	target
Exisulind	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Exisulind	cGMP-dependent 3',5'-cyclic phosphodiesterase	target
Exisulind	Glutathione S-transferase P	target
Exisulind	Aldose reductase	target
Exisulind	Aldo-keto reductase family 1 member B10	target
Udenafil	cGMP-specific 3',5'-cyclic phosphodiesterase	target
Udenafil	Cytochrome P450 3A4	enzyme
Udenafil	Cytochrome P450 3A5	enzyme
Temsirolimus	Serine/threonine-protein kinase mTOR	target
Temsirolimus	Cytochrome P450 3A4	enzyme
Temsirolimus	Cytochrome P450 3A5	enzyme
Temsirolimus	Cytochrome P450 3A7	enzyme
Temsirolimus	Cytochrome P450 2D6	enzyme
Temsirolimus	P-glycoprotein 1	transporter
Darapladib	Cytosolic phospholipase A2	target
Iclaprim	Dihydrofolate reductase	target
Indisulam	Cytochrome P450 2C9	enzyme
Indisulam	Cytochrome P450 3A4	enzyme
Indisulam	Cytochrome P450 2E1	enzyme
Indisulam	Cytochrome P450 2D6	enzyme
Etravirine	Cytochrome P450 2C19	enzyme
Etravirine	Cytochrome P450 2C9	enzyme
Etravirine	Cytochrome P450 3A4	enzyme
Etravirine	Gag-Pol polyprotein	target
Etravirine	Gag-Pol polyprotein	target
Etravirine	P-glycoprotein 1	transporter
Etravirine	Multidrug resistance protein 3	transporter
Etravirine	Reverse transcriptase/RNaseH	target
Semaxanib	Vascular endothelial growth factor receptor 2	target
Semaxanib	Prostaglandin G/H synthase 2	enzyme
Midostaurin	Protein kinase C alpha type	target
Midostaurin	Vascular endothelial growth factor receptor 2	target
Midostaurin	Mast/stem cell growth factor receptor Kit	target
Midostaurin	Platelet-derived growth factor receptor alpha	target
Midostaurin	Platelet-derived growth factor receptor beta	target
Midostaurin	Receptor-type tyrosine-protein kinase FLT3	target
Midostaurin	Cytochrome P450 3A Subfamily	enzyme
Midostaurin	Cytochrome P450 1A2	enzyme
Midostaurin	Cytochrome P450 2B6	enzyme
Midostaurin	Cytochrome P450 2C8	enzyme
Midostaurin	Cytochrome P450 2C9	enzyme
Midostaurin	Cytochrome P450 2C19	enzyme
Midostaurin	Cytochrome P450 2D6	enzyme
Midostaurin	Cytochrome P450 2E1	enzyme
Midostaurin	Cytochrome P450 3A4	enzyme
Midostaurin	Cytochrome P450 3A5	enzyme
Midostaurin	Cytochrome P450 3A7	enzyme
Midostaurin	Cytochrome P450 3A43	enzyme
Panobinostat	Cytochrome P450 2D6	enzyme
Panobinostat	Cytochrome P450 3A4	enzyme
Panobinostat	P-glycoprotein 1	transporter
Panobinostat	Histone deacetylase	target
Mevastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	target
Mevastatin	Liver carboxylesterase 1	enzyme
Mafenide	Carbonic anhydrase 6	target
Plicamycin	DNA	target
Viomycin	16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA	target
Veliparib	Poly [ADP-ribose] polymerase 1	target
Veliparib	Poly [ADP-ribose] polymerase 2	target
4-(2-Aminoethyl)Benzenesulfonyl Fluoride	Glyceraldehyde-3-phosphate dehydrogenase	target
4-(2-Aminoethyl)Benzenesulfonyl Fluoride	V-type proton ATPase subunit B, brain isoform	target
Brefeldin A	Cytohesin-2	target
Brefeldin A	ADP-ribosylation factor 1	target
Brefeldin A	Cytochrome P450 3A4	enzyme
Anisomycin	60S ribosomal protein L10-like	target
Anisomycin	60S ribosomal protein L13a	target
Anisomycin	60S ribosomal protein L23	target
Anisomycin	60S ribosomal protein L15	target
Anisomycin	60S ribosomal protein L19	target
Anisomycin	60S ribosomal protein L23a	target
Anisomycin	Probable ribosome biogenesis protein RLP24	target
Anisomycin	60S ribosomal protein L26-like 1	target
Anisomycin	60S ribosomal protein L8	target
Anisomycin	60S ribosomal protein L37	target
Anisomycin	60S ribosomal protein L3	target
Anisomycin	60S ribosomal protein L11	target
Anisomycin	NHP2-like protein 1	target
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide	Stromelysin-1	target
Emodin	Casein kinase II subunit alpha	target
Emodin	Putative ketoacyl reductase	target
Emodin	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ	target
Emodin	Aryl hydrocarbon receptor	target
Harmine	Amine oxidase [flavin-containing] A	target
3-isobutyl-1-methyl-7H-xanthine	cGMP-specific 3',5'-cyclic phosphodiesterase	target
3-isobutyl-1-methyl-7H-xanthine	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	target
3-isobutyl-1-methyl-7H-xanthine	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	target
3-isobutyl-1-methyl-7H-xanthine	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	target
3-isobutyl-1-methyl-7H-xanthine	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	target
3-isobutyl-1-methyl-7H-xanthine	High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	target
3-isobutyl-1-methyl-7H-xanthine	cGMP-dependent 3',5'-cyclic phosphodiesterase	target
3-isobutyl-1-methyl-7H-xanthine	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	target
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide	Stromelysin-1	target
Wortmannin	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	target
Wortmannin	Serine/threonine-protein kinase PLK1	target
Wortmannin	Phosphatidylinositol 3-kinase regulatory subunit alpha	target
Wortmannin	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	target
Fasudil	cAMP-dependent protein kinase inhibitor alpha	target
Fasudil	cAMP-dependent protein kinase catalytic subunit alpha	target
Fasudil	Rho-associated protein kinase 1	target
Fasudil	Rho-associated protein kinase 2	target
Emivirine	Gag-Pol polyprotein	target
Puromycin	60S ribosomal protein L10-like	target
Puromycin	60S ribosomal protein L13a	target
Puromycin	60S ribosomal protein L23	target
Puromycin	60S ribosomal protein L15	target
Puromycin	60S ribosomal protein L19	target
Puromycin	60S ribosomal protein L23a	target
Puromycin	Probable ribosome biogenesis protein RLP24	target
Puromycin	60S ribosomal protein L26-like 1	target
Puromycin	60S ribosomal protein L8	target
Puromycin	60S ribosomal protein L37	target
Puromycin	60S ribosomal protein L3	target
Puromycin	60S ribosomal protein L11	target
Puromycin	Leucyl/phenylalanyl-tRNA--protein transferase	target
Parecoxib	Lactotransferrin	target
Parecoxib	Prostaglandin G/H synthase 2	target
Parecoxib	Cytochrome P450 3A4	enzyme
Parecoxib	Cytochrome P450 2C9	enzyme
Capravirine	Cytochrome P450 3A4	enzyme
Capravirine	Gag-Pol polyprotein	target
Capravirine	Cytochrome P450 2C8	enzyme
Capravirine	Cytochrome P450 2C9	enzyme
Capravirine	Cytochrome P450 2C19	enzyme
Capravirine	Reverse transcriptase/RNaseH	target
Aminopterin	Proton-coupled folate transporter	transporter
Aminopterin	Dihydrofolate reductase	enzyme
Vemurafenib	Serum albumin	carrier
Vemurafenib	Alpha-1-acid glycoprotein 1	carrier
Vemurafenib	Cytochrome P450 1A2	enzyme
Vemurafenib	Cytochrome P450 2D6	enzyme
Vemurafenib	Cytochrome P450 3A4	enzyme
Vemurafenib	Serine/threonine-protein kinase B-raf	target
Vemurafenib	Multidrug resistance-associated protein 1	transporter
Vemurafenib	ATP-binding cassette sub-family G member 2	transporter
Vemurafenib	Cytochrome P450 2C9	enzyme
Vemurafenib	Cytochrome P450 2C8	enzyme
Vemurafenib	Cytochrome P450 2B6	enzyme
Vemurafenib	P-glycoprotein 1	transporter
Tofacitinib	Non-receptor tyrosine-protein kinase TYK2	target
Tofacitinib	Cytochrome P450 3A4	enzyme
Tofacitinib	Cytochrome P450 2C19	enzyme
Tofacitinib	Tyrosine-protein kinase JAK2	target
Tofacitinib	Tyrosine-protein kinase JAK1	target
Tofacitinib	Tyrosine-protein kinase JAK3	target
Tofacitinib	Serum albumin	carrier
Ponatinib	Tyrosine-protein kinase ABL1	target
Ponatinib	Breakpoint cluster region protein	target
Ponatinib	Mast/stem cell growth factor receptor Kit	target
Ponatinib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
Ponatinib	Angiopoietin-1 receptor	target
Ponatinib	Receptor-type tyrosine-protein kinase FLT3	target
Ponatinib	Cytochrome P450 3A4	enzyme
Ponatinib	Cytochrome P450 2C8	enzyme
Ponatinib	Cytochrome P450 2D6	enzyme
Ponatinib	Cytochrome P450 3A5	enzyme
Ponatinib	P-glycoprotein 1	transporter
Ponatinib	ATP-binding cassette sub-family G member 2	transporter
Ponatinib	Fibroblast growth factor receptor 1	target
Ponatinib	Fibroblast growth factor receptor 2	target
Ponatinib	Fibroblast growth factor receptor 3	target
Ponatinib	Fibroblast growth factor receptor 4	target
Ponatinib	Tyrosine-protein kinase Lck	target
Ponatinib	Proto-oncogene tyrosine-protein kinase Src	target
Ponatinib	Tyrosine-protein kinase Lyn	target
Ponatinib	Vascular endothelial growth factor receptor 2	target
Ponatinib	Platelet-derived growth factor receptor alpha	target
Trametinib	Cytochrome P450 2C8	enzyme
Trametinib	Cytochrome P450 3A4	enzyme
Trametinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Trametinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Afatinib	Epidermal growth factor receptor	target
Afatinib	Receptor tyrosine-protein kinase erbB-2	target
Afatinib	Receptor tyrosine-protein kinase erbB-4	target
Afatinib	P-glycoprotein 1	transporter
Afatinib	ATP-binding cassette sub-family G member 2	transporter
Indoprofen	Pyruvate kinase PKM	target
Flumequine	Cytochrome P450 1A2	enzyme
Finafloxacin	DNA gyrase subunit A	target
Finafloxacin	DNA topoisomerase 4 subunit A	target
Finafloxacin	DNA topoisomerase 2-alpha	target
Chlortetracycline	16S ribosomal RNA	target
Chlortetracycline	Serum albumin	carrier
Chlortetracycline	30S ribosomal protein S3	target
Chlortetracycline	30S ribosomal protein S8	target
Chlortetracycline	30S ribosomal protein S19	target
Chlortetracycline	30S ribosomal protein S14	target
Chlortetracycline	30S ribosomal protein S7	target
Chlortetracycline	ADP-ribosylation factor 1	target
Chlortetracycline	Catalase	target
Chlortetracycline	Ephrin type-B receptor 1	target
Chlortetracycline	Pancreatic triacylglycerol lipase	target
Chlortetracycline	Protein-arginine deiminase type-4	target
Elvitegravir	Integrase	target
Elvitegravir	Cytochrome P450 3A4	enzyme
Elvitegravir	UDP-glucuronosyltransferase 1-1	enzyme
Pirlindole	Amine oxidase [flavin-containing] A	target
Pirlindole	5-hydroxytryptamine receptor 1A	target
Pirlindole	Alpha-2A adrenergic receptor	target
Pirlindole	Amine oxidase [flavin-containing] A	enzyme
Toloxatone	Amine oxidase [flavin-containing] A	target
Toloxatone	Amine oxidase [flavin-containing] A	enzyme
Doxofylline	Adenosine receptor A2a	target
Doxofylline	Beta-2 adrenergic receptor	target
Doxofylline	Cytochrome P450 1A2	enzyme
Doxofylline	cGMP-dependent 3',5'-cyclic phosphodiesterase	target
Trapidil	Platelet-derived growth factor receptor beta	target
Trapidil	Cyclic nucleotide phosphodiesterase	target
Alirocumab	Proprotein convertase subtilisin/kexin type 9	target
Evolocumab	Proprotein convertase subtilisin/kexin type 9	target
Sulbactam	Beta-lactamase	target
Dichlorvos	Serum albumin	carrier
Dichlorvos	Serotransferrin	target
Dichlorvos	Cholinesterase	target
Monensin	P-glycoprotein 1	transporter
Pimobendan	Cytochrome P450 1A2	enzyme
Tucatinib	Receptor tyrosine-protein kinase erbB-2	target
Tucatinib	ATP-binding cassette sub-family G member 2	transporter
Tucatinib	P-glycoprotein 1	transporter
Tucatinib	Solute carrier family 22 member 2	transporter
Tucatinib	Multidrug and toxin extrusion protein 1	transporter
Tucatinib	Multidrug and toxin extrusion protein 2	transporter
Tucatinib	Cytochrome P450 2C8	enzyme
Tucatinib	Cytochrome P450 3A Subfamily	enzyme
Tucatinib	Receptor tyrosine-protein kinase erbB-2	enzyme
Tucatinib	Receptor tyrosine-protein kinase erbB-3	target
Cabotegravir	Solute carrier family 22 member 6	transporter
Cabotegravir	Solute carrier family 22 member 8	transporter
Cabotegravir	UDP-glucuronosyltransferase 1-1	enzyme
Cabotegravir	UDP-glucuronosyltransferase 1-9	enzyme
Cabotegravir	P-glycoprotein 1	transporter
Cabotegravir	ATP-binding cassette sub-family G member 2	transporter
Cabotegravir	Serum albumin	carrier
Cabotegravir	Integrase	target
Momelotinib	Cytochrome P450 3A4	enzyme
Momelotinib	Cytochrome P450 2C8	enzyme
Momelotinib	Cytochrome P450 2C9	enzyme
Momelotinib	Cytochrome P450 2C19	enzyme
Momelotinib	Cytochrome P450 1A2	enzyme
Momelotinib	Cytochrome P450 2B6	enzyme
Momelotinib	UDP-glucuronosyltransferase 1-1	enzyme
Momelotinib	UDP-glucuronosyltransferase 1-9	enzyme
Momelotinib	P-glycoprotein 1	transporter
Momelotinib	ATP-binding cassette sub-family G member 2	transporter
Momelotinib	Solute carrier organic anion transporter family member 1B1	transporter
Momelotinib	Solute carrier organic anion transporter family member 1B3	transporter
Momelotinib	Tyrosine-protein kinase JAK1	target
Momelotinib	Tyrosine-protein kinase JAK2	target
Momelotinib	Tyrosine-protein kinase JAK3	target
Momelotinib	Non-receptor tyrosine-protein kinase TYK2	target
Momelotinib	Activin receptor type-1	target
Momelotinib	Receptor-type tyrosine-protein kinase FLT3	target
Spebrutinib	Tyrosine-protein kinase BTK	target
Pazufloxacin	Cytochrome P450 1A2	enzyme
Mirodenafil	Cytochrome P450 3A Subfamily	enzyme
Niraparib	Poly [ADP-ribose] polymerase 1	target
Niraparib	Poly [ADP-ribose] polymerase 2	target
Niraparib	Carboxylesterase	enzyme
Niraparib	Cytochrome P450 1A2	enzyme
Niraparib	ATP-binding cassette sub-family G member 2	transporter
Niraparib	Multidrug and toxin extrusion protein 1	transporter
Niraparib	Multidrug and toxin extrusion protein 2	transporter
Niraparib	P-glycoprotein 1	transporter
Niraparib	Serum albumin	carrier
Mocetinostat	Histone deacetylase 1	target
Mocetinostat	Histone deacetylase 3	target
Mocetinostat	Histone deacetylase 2	target
Entinostat	Histone deacetylase	target
Prulifloxacin	Cytochrome P450 1A2	enzyme
Lapachone	Retinol-binding protein 3	target
Tesevatinib	Pro-epidermal growth factor	target
Tesevatinib	Ephrin type-B receptor 4	target
Tesevatinib	Receptor tyrosine-protein kinase erbB-2	target
Nirogacestat	Presenilin-1	target
Nirogacestat	Cytochrome P450 3A4	enzyme
Nirogacestat	Cytochrome P450 2C9	enzyme
Nirogacestat	Cytochrome P450 2C19	enzyme
Nirogacestat	Cytochrome P450 2D6	enzyme
Nirogacestat	Cytochrome P450 2B6	enzyme
Nirogacestat	Serum albumin	carrier
Nirogacestat	alpha1-acid glycoprotein	carrier
Nirogacestat	P-glycoprotein 1	transporter
Nirogacestat	Cytochrome P450 2C8	enzyme
Prexasertib	Serine/threonine-protein kinase Chk1	target
Letermovir	UDP-glucuronosyltransferase 1-1	enzyme
Letermovir	UDP-glucuronosyltransferase 1-3	enzyme
Letermovir	Solute carrier organic anion transporter family member 1B1	transporter
Letermovir	Solute carrier organic anion transporter family member 1B3	transporter
Letermovir	Cytochrome P450 2D6	enzyme
Letermovir	Cytochrome P450 2C8	enzyme
Letermovir	Cytochrome P450 2C19	enzyme
Letermovir	Cytochrome P450 2C9	enzyme
Letermovir	Cytochrome P450 2B6	enzyme
Letermovir	P-glycoprotein 1	transporter
Letermovir	ATP-binding cassette sub-family G member 2	transporter
Letermovir	Bile salt export pump	transporter
Letermovir	Solute carrier family 22 member 8	transporter
Letermovir	Canalicular multispecific organic anion transporter 1	transporter
Letermovir	CMV DNA Terminase Complex	target
Letermovir	Cytochrome P450 3A Subfamily	enzyme
Vinpocetine	Cytochrome P450 3A4	enzyme
Rucaparib	Poly [ADP-ribose] polymerase 1	target
Rucaparib	Poly [ADP-ribose] polymerase 2	target
Rucaparib	Poly [ADP-ribose] polymerase 3	target
Rucaparib	Cytochrome P450 2D6	enzyme
Rucaparib	Cytochrome P450 1A2	enzyme
Rucaparib	Cytochrome P450 3A4	enzyme
Rucaparib	P-glycoprotein 1	transporter
Rucaparib	ATP-binding cassette sub-family G member 2	transporter
Rucaparib	Multidrug and toxin extrusion protein 1	transporter
Rucaparib	Multidrug and toxin extrusion protein 2	transporter
Rucaparib	Solute carrier family 22 member 1	transporter
Rucaparib	Multidrug resistance-associated protein 4	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B1	transporter
Rucaparib	Solute carrier organic anion transporter family member 1B3	transporter
Rucaparib	Solute carrier family 22 member 6	transporter
Rucaparib	Solute carrier family 22 member 8	transporter
Rucaparib	Cytochrome P450 3A5	enzyme
Rucaparib	Cytochrome P450 3A7	enzyme
Rucaparib	Cytochrome P450 3A43	enzyme
Rucaparib	Cytochrome P450 2C19	enzyme
Rucaparib	Cytochrome P450 2C9	enzyme
Rucaparib	Cytochrome P450 2C8	enzyme
Rucaparib	UDP-glucuronosyltransferase 1-1	enzyme
Dexelvucitabine	Reverse transcriptase/RNaseH	target
Abexinostat	Histone deacetylase 1	target
Abexinostat	Histone deacetylase	target
Piperine	Nuclear receptor subfamily 1 group I member 2	target
Piperine	Cytochrome P450 3A4	enzyme
Piperine	P-glycoprotein 1	transporter
Ebselen	Bifunctional epoxide hydrolase 2	target
PF-477736	Serine/threonine-protein kinase Chk1	target
Lometrexol	Dihydrofolate reductase	target
MK-0752	Gamma-secretase subunit APH-1A	target
Talarozole	Cytochrome P450 26A1	target
Sitafloxacin	Cytochrome P450 1A2	enzyme
Dexrabeprazole	Cytochrome P450 2C19	enzyme
Rufloxacin	Cytochrome P450 1A2	enzyme
Adefovir	DNA polymerase/reverse transcriptase	target
Harmaline	Histamine N-methyltransferase	target
Brofaromine	Amine oxidase [flavin-containing] A	target
Iniparib	Poly [ADP-ribose] polymerase 1	target
Clinafloxacin	Cytochrome P450 1A2	enzyme
Clinafloxacin	Cytochrome P450 2C19	enzyme
Clinafloxacin	Cytochrome P450 2D6	enzyme
Clinafloxacin	Cytochrome P450 2C9	enzyme
Furafylline	Cytochrome P450 1A2	enzyme
SC-236	Cyclooxygenase 2	target
SC-236	Nuclear factor NF-kappa-B complex	target
NS-398	Cyclooxygenase 2	target
NS-398	Prostaglandin G/H synthase 2	enzyme
Elapegademase	Adenosine	target
Abrocitinib	Cytochrome P450 2C19	enzyme
Abrocitinib	Cytochrome P450 2C9	enzyme
Abrocitinib	Cytochrome P450 3A4	enzyme
Abrocitinib	Cytochrome P450 2B6	enzyme
Abrocitinib	Tyrosine-protein kinase JAK1	target
Abrocitinib	P-glycoprotein 1	transporter
Abrocitinib	Solute carrier family 22 member 1	transporter
Abrocitinib	Tyrosine-protein kinase JAK2	target
Abrocitinib	Tyrosine-protein kinase JAK3	target
Abrocitinib	Non-receptor tyrosine-protein kinase TYK2	target
Abrocitinib	Serum albumin	carrier
Abrocitinib	Solute carrier family 22 member 8	transporter
Abivertinib	Epidermal growth factor receptor	target
Abivertinib	Tyrosine-protein kinase BTK	target
Branebrutinib	Tyrosine-protein kinase BTK	target
Ursolic acid	GTPase HRas	target
Ursolic acid	Neutrophil elastase	target
Veliflapon	Arachidonate 5-lipoxygenase-activating protein	target
Deucravacitinib	Non-receptor tyrosine-protein kinase TYK2	target
Deucravacitinib	Cytochrome P450 1A2	enzyme
Deucravacitinib	Cytochrome P450 2B6	enzyme
Deucravacitinib	Cytochrome P450 2D6	enzyme
Deucravacitinib	Cocaine esterase	enzyme
Deucravacitinib	UDP-glucuronosyltransferase 1-9	enzyme
Deucravacitinib	P-glycoprotein 1	transporter
Deucravacitinib	ATP-binding cassette sub-family G member 2	transporter
Deucravacitinib	Solute carrier family 22 member 1	transporter
Deucravacitinib	Solute carrier organic anion transporter family member 1B3	transporter
Belumosudil	Rho-associated protein kinase 2	target
Belumosudil	Serum albumin	carrier
Belumosudil	Alpha-1-acid glycoprotein 1	carrier
Belumosudil	Rho-associated protein kinase 1	target
Belumosudil	Cytochrome P450 3A4	enzyme
Belumosudil	Cytochrome P450 2C8	enzyme
Belumosudil	Cytochrome P450 2D6	enzyme
Belumosudil	UDP-glucuronosyltransferase 1-9	enzyme
Belumosudil	Cytochrome P450 1A2	enzyme
Belumosudil	Cytochrome P450 2C19	enzyme
Belumosudil	UDP-glucuronosyltransferase 1-1	enzyme
Belumosudil	P-glycoprotein 1	transporter
Belumosudil	ATP-binding cassette sub-family G member 2	transporter
Belumosudil	Solute carrier organic anion transporter family member 1B1	transporter
MK-886	Arachidonate 5-lipoxygenase-activating protein	target
Olutasidenib	Isocitrate dehydrogenase [NADP] cytoplasmic	target
Olutasidenib	Cytochrome P450 3A4	enzyme
Olutasidenib	Cytochrome P450 2C8	enzyme
Olutasidenib	Cytochrome P450 2C9	enzyme
Olutasidenib	Cytochrome P450 1A2	enzyme
Olutasidenib	Cytochrome P450 2C19	enzyme
Olutasidenib	P-glycoprotein 1	transporter
Olutasidenib	ATP-binding cassette sub-family G member 2	transporter
Olutasidenib	Solute carrier organic anion transporter family member 1B1	transporter
Olutasidenib	Solute carrier organic anion transporter family member 1B3	transporter
Olutasidenib	Solute carrier family 22 member 8	transporter
Olutasidenib	Solute carrier family 22 member 2	transporter
Olutasidenib	Multidrug and toxin extrusion protein 1	transporter
Olutasidenib	Multidrug and toxin extrusion protein 2	transporter
Olutasidenib	Cytochrome P450 2B6	enzyme
Everolimus	Serine/threonine-protein kinase mTOR	target
Everolimus	Cytochrome P450 3A4	enzyme
Everolimus	Solute carrier organic anion transporter family member 1B1	transporter
Everolimus	Solute carrier organic anion transporter family member 1B3	transporter
Everolimus	Solute carrier organic anion transporter family member 1A2	transporter
Everolimus	Cytochrome P450 2D6	enzyme
Everolimus	P-glycoprotein 1	transporter
Tivozanib	Cytochrome P450 3A4	enzyme
Tivozanib	Serum albumin	carrier
Tivozanib	Vascular endothelial growth factor receptor 1	target
Tivozanib	Vascular endothelial growth factor receptor 2	target
Tivozanib	Vascular endothelial growth factor receptor 3	target
Tivozanib	Mast/stem cell growth factor receptor Kit	target
Tivozanib	Platelet-derived growth factor receptor beta	target
Tivozanib	P-glycoprotein 1	transporter
Tivozanib	ATP-binding cassette sub-family G member 2	transporter
Tivozanib	Receptor-type tyrosine-protein kinase FLT3	target
Tivozanib	Platelet-derived growth factor receptor alpha	target
Tivozanib	Protein-tyrosine kinase 6	target
Tivozanib	Angiopoietin-1 receptor	target
Tivozanib	Fibroblast growth factor receptor 1	target
Tivozanib	Hepatocyte growth factor receptor	target
Ozenoxacin	DNA gyrase subunit A	target
Ozenoxacin	DNA topoisomerase 4 subunit A	target
GC-376 free acid	Replicase polyprotein 1ab	target
GC-376 free acid	Replicase polyprotein 1a	target
GC-376 free acid	Replicase polyprotein 1ab	target
GC-376 free acid	Replicase polyprotein 1a	target
GC-376 free acid	Replicase polyprotein 1ab	target
Pirtobrutinib	Cytochrome P450 3A4	enzyme
Pirtobrutinib	UDP-glucuronosyltransferase 1-8	enzyme
Pirtobrutinib	UDP-glucuronosyltransferase 1-9	enzyme
Pirtobrutinib	Cytochrome P450 2C8	enzyme
Pirtobrutinib	Cytochrome P450 2C9	enzyme
Pirtobrutinib	Cytochrome P450 1A2	enzyme
Pirtobrutinib	Cytochrome P450 2B6	enzyme
Pirtobrutinib	Cytochrome P450 2C19	enzyme
Pirtobrutinib	Cytochrome P450 2D6	enzyme
Pirtobrutinib	Cytochrome P450 3A5	enzyme
Pirtobrutinib	Tyrosine-protein kinase BTK	target
Pirtobrutinib	P-glycoprotein 1	transporter
Pirtobrutinib	ATP-binding cassette sub-family G member 2	transporter
Durlobactam	Solute carrier family 22 member 6	transporter
Nilotinib	Tyrosine-protein kinase ABL1	target
Nilotinib	Mast/stem cell growth factor receptor Kit	target
Nilotinib	Cytochrome P450 2D6	enzyme
Nilotinib	Cytochrome P450 2C8	enzyme
Nilotinib	Cytochrome P450 2C9	enzyme
Nilotinib	Cytochrome P450 3A4	enzyme
Nilotinib	P-glycoprotein 1	transporter
Nilotinib	ATP-binding cassette sub-family G member 2	transporter
Nilotinib	UDP-glucuronosyltransferase 1-1	transporter
Nilotinib	Cytochrome P450 2B6	enzyme
Nilotinib	Solute carrier organic anion transporter family member 1B1	transporter
Bosutinib	Tyrosine-protein kinase ABL1	target
Bosutinib	Tyrosine-protein kinase Lyn	target
Bosutinib	Proto-oncogene tyrosine-protein kinase Src	target
Bosutinib	P-glycoprotein 1	transporter
Bosutinib	Cytochrome P450 3A4	enzyme
Bosutinib	Dual specificity mitogen-activated protein kinase kinase 1	target
Bosutinib	Dual specificity mitogen-activated protein kinase kinase 2	target
Bosutinib	Mitogen-activated protein kinase kinase kinase 2	target
Bosutinib	Calcium/calmodulin-dependent protein kinase type II subunit gamma	target
Bosutinib	Cytochrome P450 2C8	enzyme
Bosutinib	Tyrosine-protein kinase Fgr	target
Bosutinib	Tyrosine-protein kinase HCK	target
Bosutinib	Tyrosine-protein kinase Tec	target
Bosutinib	STE20-like serine/threonine-protein kinase	target
Aliskiren	Renin	target
Aliskiren	Cytochrome P450 3A4	enzyme
Aliskiren	P-glycoprotein 1	transporter
Ibrutinib	Tyrosine-protein kinase BTK	target
Ibrutinib	Cytochrome P450 3A4	enzyme
Ibrutinib	Cytochrome P450 3A5	enzyme
Ibrutinib	Serum albumin	carrier
Ibrutinib	alpha1-acid glycoprotein	carrier
Ibrutinib	Cytochrome P450 2D6	enzyme
Alectinib	ALK tyrosine kinase receptor	target
Alectinib	ATP-binding cassette sub-family G member 2	transporter
Alectinib	P-glycoprotein 1	transporter
Acalabrutinib	Tyrosine-protein kinase BTK	target
Acalabrutinib	Cytochrome P450 3A4	enzyme
Acalabrutinib	Cytochrome P450 3A5	enzyme
Acalabrutinib	Cytochrome P450 3A Subfamily	enzyme
Acalabrutinib	Serum albumin	carrier
Acalabrutinib	alpha1-acid glycoprotein	carrier
Neratinib	Cytochrome P450 3A4	enzyme
Neratinib	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
Neratinib	P-glycoprotein 1	transporter
Neratinib	Epidermal growth factor receptor	target
Neratinib	Serum albumin	carrier
Neratinib	alpha1-acid glycoprotein	carrier
Dacomitinib	Cytochrome P450 2D6	enzyme
Dacomitinib	Serum albumin	carrier
Dacomitinib	Cytochrome P450 3A4	enzyme
Dacomitinib	Cytochrome P450 2C9	enzyme
Dacomitinib	UDP-glucuronosyltransferase 1-1	enzyme
Dacomitinib	P-glycoprotein 1	transporter
Dacomitinib	ATP-binding cassette sub-family G member 2	transporter
Dacomitinib	Solute carrier family 22 member 1	transporter
Dacomitinib	Epidermal growth factor receptor	target
Gilteritinib	Serum albumin	carrier
Gilteritinib	Cytochrome P450 3A4	enzyme
Gilteritinib	Receptor-type tyrosine-protein kinase FLT3	target
Gilteritinib	Serotonin Receptors	target
Gilteritinib	P-glycoprotein 1	transporter
Gilteritinib	Multidrug and toxin extrusion protein 1	transporter
Gilteritinib	ATP-binding cassette sub-family G member 2	transporter
Gilteritinib	Solute carrier family 22 member 1	transporter
Gilteritinib	Tyrosine-protein kinase receptor UFO	target
Gilteritinib	ALK tyrosine kinase receptor	target
Asciminib	Cytochrome P450 3A4	enzyme
Asciminib	UDP-glucuronosyltransferase 2B7	enzyme
Asciminib	UDP-glucuronosyltransferase 2B17	enzyme
Asciminib	Tyrosine-protein kinase ABL1	target
Asciminib	ATP-binding cassette sub-family G member 2	transporter
Asciminib	UDP-glucuronosyltransferase 1-1	enzyme
Asciminib	Cytochrome P450 2C19	enzyme
Asciminib	P-glycoprotein 1	transporter
Asciminib	Solute carrier organic anion transporter family member 1B1	transporter
Asciminib	Solute carrier organic anion transporter family member 1B3	transporter
Asciminib	Solute carrier family 22 member 1	transporter
Asciminib	Cytochrome P450 2C9	enzyme
Quizartinib	Receptor-type tyrosine-protein kinase FLT3	target
Quizartinib	Cytochrome P450 3A4	enzyme
Quizartinib	Cytochrome P450 3A5	enzyme
Quizartinib	UDP-glucuronosyltransferase 1-1	enzyme
Quizartinib	P-glycoprotein 1	transporter
Quizartinib	ATP-binding cassette sub-family G member 2	transporter
Quizartinib	Serum albumin	carrier
Quizartinib	Cytochrome P450 3A7	enzyme
Mobocertinib	Epidermal growth factor receptor	target
Mobocertinib	Cytochrome P450 3A4	enzyme
Mobocertinib	Cytochrome P450 3A5	enzyme
Mobocertinib	Cytochrome P450 3A7	enzyme
Mobocertinib	P-glycoprotein 1	transporter
Mobocertinib	ATP-binding cassette sub-family G member 2	transporter