Cardiovascular Agents

Name
Cardiovascular Agents
Accession Number
DBCAT000010
Description

Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.

Drugs
DrugDrug Description
LepirudinA protein-based direct thrombin inhibitor used as an anticoagulant in patients with heparin-induced thrombocytopenia.
AlteplaseA recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
ReteplaseA purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
AnistreplaseA form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
TenecteplaseA modified form of recombinant human tissue plasminogen activator used in the emergency treatment of myocardial infarction and pulmonary emboli.
DesmopressinA synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
VasopressinA peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy.
ValsartanAn angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
RamiprilAn ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
BetaxololA cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
MidodrineAn alpha-adrenergic agonist used to treat orthostatic hypotension.
TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
BethanidineFor the treatment of hypertension.
GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
GuanadrelUsed to treat and control hypertension.
MilrinoneA PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure.
RanolazineAn anti-anginal drug used for the treatment of chronic angina.
MethysergideAn ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
AnagrelideA platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
MetoprololA beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
OlmesartanAn angiotensin receptor blocker (ARB) used in the treatment of hypertension.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
DisopyramideA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
IbutilideA class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
AtenololA synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
TimololA non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
AmlodipineA calcium channel blocker used to treat hypertension and angina.
TriamtereneA potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
PhenylephrineAn alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DigoxinA cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
NimodipineA calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
NisoldipineA calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
CarbamoylcholineA direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery.
SpironolactoneAn aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism.
HyoscyamineAn anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
BendroflumethiazideA diuretic used to suppress lactation and to treat hypertension and edema.
PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
BrimonidineAn alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea.
SotalolA methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.
FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
AcetyldigitoxinUsed for fast digitalization in congestive heart failure.
TrandolaprilA prodrug of an ACE inhibitor used to treat hypertension, congestive heart failure, and to improve survival following a myocardial infarction.
CarteololA beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
MetolazoneA thiazide-like diuretic used to treat hypertension.
LercanidipineA calcium channel blocker for the management of hypertension.
BenazeprilAn ACE inhibitor prodrug used to treat hypertension.
PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
EnalaprilA prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
DoxazosinAn alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
AmilorideA pyrizine compound used to treat hypertension and congestive heart failure.
UlobetasolA lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either...
BisoprololA beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
NiacinA B vitamin used to treat hypertriglyceridemia and pellagra.
AdenosineA medication used in myocardial perfusion scintigraphy and to treat supraventricular tachycardia.
DyphyllineA theophylline derivative used to treat asthma, bronchospasm, and COPD.
VerapamilA non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
MoexiprilAn angiotensin converting enzyme inhibitor prodrug used to treat hypertension.
PhentolamineAn alpha-adrenergic blocker used to treat hypertensive episodes, diagnose pheochromocytoma, treat norepinephrine administration site reactions, and reverse soft tissue anesthesia and mydriasis.
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
ErgotamineAn alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
EplerenoneAn aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
MethazolamideA carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
LisinoprilAn ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
NitroglycerinA nitrate vasodilator used to treat or prevent angina, heart failure, hypertension, and anal fissures.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
TirofibanA platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome.
CryptenamineFor the treatment of hypertension.
PerindoprilAn ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction.
Candesartan cilexetilAn angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy.
TolazolineA vasodilator used to treat pulmonary artery anomalies.
FenoldopamA dopamine D1 receptor agonist used for the short term management of hypertension.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
AlprenololFor the treatment of hypertension, angina, and arrhythmia
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
EprosartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
QuinaprilAn ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
CocaineAn ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
PhenoxybenzamineAn alpha adrenergic antagonist used to treat pheochromocytoma and episodes of hypertension and sweating.
OxymetazolineAn alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
PindololA beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation.
TelmisartanAn ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
MethyldopaA centrally-acting alpha-2 adrenergic agonist used to manage hypertension alone or in combination with hydrochlorothiazide, and to treat hypertensive crises.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
GuanfacineAn alpha-2A adrenergic receptor agonist used to treat ADHD.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
IrbesartanAn angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
ProcainamideA medication used to treat life threatening ventricular arrhythmias.
Ergoloid mesylateA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
TocainideAn orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
IsoprenalineA catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block.
DeslanosideFor the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
PentoliniumUsed to produce controlled hypotension during surgical procedures and in hypertensive crises.
OuabainFor the treatment of atrial fibrillation and flutter and heart failure
ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
BretyliumA norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias.
GuanethidineAn antihypertensive agent used in the management of moderate and severe hypertension, either alone or as an adjunct, and for the management of renal hypertension.
PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
FlecainideA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
NadololA non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension.
MetipranololA beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
EnoxaparinA low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction.
EpoprostenolA vasodilator and platelet aggregation inhibitor used for the management of primary pulmonary hypertension and pulmonary hypertension in patients with heart failure.
HydralazineAn antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia .
PirbuterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
PractololUsed in the emergency treatment of cardiac arrhythmias.
PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
QuinethazoneUsed to treat hypertension.
CilazaprilAn ACE inhibitor used for the management of hypertension and heart failure.
SpiraprilSpirapril is an ACE inhibitor class drug used to treat hypertension.
EphedrineAn alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion.
MephentermineA sympathomimetic agent used in the treatment of hypotension.
AmrinoneA positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
OxprenololA non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety.
Amyl NitriteA fast acting vasodilator used for rapid relief of angina pectoris.
PargylineFor the treatment of moderate to severe hypertension.
PiretanideA loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin.
AcetylcholineA parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.
CyclandelateA vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
FlunarizineA selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
TolvaptanA selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia.
XylometazolineA direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds.
LevonordefrinA topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures.
NaphazolineA sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.
DrotaverineA phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
PinacidilPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
TetryzolineAn alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion.
PolidocanolA sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity.
TinzaparinA low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin.
UnoprostoneA prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents.
TrimetazidineA piperazine derivative indicated as an adjunct therapy in symptomatic treatment of stable angina pectoris.
IvabradineA HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients.
ManidipineA dihydropyridine calcium channel blocker used to treat hypertension.
IsosorbideA vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. It was previously used to reduce intraocular pressure.
EnalaprilatAn antihypertensive agent used for the management of hypertension when oral therapy is not practical.
DesirudinIndicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery.
RacepinephrineA bronchodilator used to treat intermittent asthma.
Protein CA medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.
SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
PimobendanNot Annotated
ZofenoprilAn ACE inhibitor indicated in the treatment of hypertension.
FlosequinanFlosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in...
HexobendineHexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has...
CyclopenthiazideCyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients...
MeldoniumNot Annotated
LidoflazineNot Annotated
LypressinNot Annotated
Eslicarbazepine acetateAn anticonvulsant agent used as an adjunct to treat partial-onset seizures in patients with inadequate clinical response to conventional antiepileptic therapy.
EslicarbazepineAn antiepileptic indicated as a monotherapy or adjunct therapy in the treatment of epilepsy.
Ginkgo bilobaA herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders.
DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
RufinamideAn antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS).
LacosamideAn antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures.
TraferminInvestigated for use/treatment in coronary artery disease, peripheral vascular disease, periodontal disease, bone fractures, entero-related fistulae, and diabetic foot ulcers.
EscinAn anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.
BMS-813160BMS-813160 is under investigation in clinical trial NCT03496662 (BMS-813160 With Nivolumab and Gemcitabine and Nab-paclitaxel in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC)).
PlasminogenPlasma-derived human plasminogen administered intravenously to treat type 1 plasminogen deficiency (hypoplasminogenemia).
beta-EscinAn anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.
PerhexilineFor the management of severe angina pectoris.
FosfructoseA phosphorylated form of fructose indicated in the treatment of hypophosphatemia.
StreptokinaseA purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism.
FelypressinFor use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential.
DofetilideA class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.
ReserpineFor the treatment of hypertension
RemikirenFor the treatment of hypertension and heart failure
IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
DexrazoxaneA cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer.
PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
ArdeparinFor prevention of deep vein thrombosis, which may result in pulmonary embolism, following knee surgery.
Sodium tetradecyl sulfateAn anionic surfactant used to treat varicose veins of the lower extremities.
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
CinnarizineA drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting.
FondaparinuxAn anticoagulant used to prevent venous thromboembolism, to treat deep vein thrombosis, and to improve survival following myocardial infarction.
MetaraminolFor the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage
CandoxatrilCandoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.
NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
GuanabenzAn alpha-2 adrenergic agonist used to treat hypertension.
Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
MecamylamineA nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension.
MoricizineAn antiarrhythmic used to treat arrhythmias.
NicergolineAn ergot derivative use for the treatment of symptoms associated with cerebrovascular abnormalities.
MethoxamineAn alpha adrenergic agonist used to treat hypotension.
EthotoinA hydantoin antiepileptic used to control tonic-clonic and complex partial seizures.
AlprostadilA prostaglandin E1 agonist used for the treatment of erectile dysfunction and as an adjunct for its diagnosis.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
OmapatrilatFor the treatment of hypertension.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
LevosimendanA calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure.
NaratriptanA 5-HT1B/1D receptor agonist used to treat migraines.
FelodipineA calcium channel blocker used to treat hypertension.
NitrendipineA dihydropyridine calcium channel blocker indicated in the treatment of arterial hypertension.
IloprostA synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH).
HeparinAn anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
EncainideA voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
FosphenytoinAn antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
SaprisartanSaprisartan is used in the treatment of hypertension and heart failure.
PenbutololA beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents.
MibefradilFor the treatment of angina and high blood pressure.
DigitoxinA cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
AjmalineAn antiarrhythmic used to manage a variety of forms of tachycardias.
AprindineAprindine is a cardiac depressant used in arrhythmias.
Erythrityl tetranitrateFor the prevention of angina.
EpicaptoprilNot Available
S-EthylisothioureaS-Ethylisothiourea is a nitric oxide synthase inhibitor.
Platelet Activating FactorNot Available
ColforsinPotent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;...
TerlipressinA drug used to treat bleeding caused by esophageal varices.
Calyculin ANot Available
PhenolAn antiseptic and disinfectant used in a variety of settings.
DexpropranololNot Available
Nicotinyl alcoholA direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem]
ErythritolErythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideNot Available
PrenylaminePrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Tienilic acidFor the treatment of hypertension.
DebrisoquineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
CeliprololA beta-blocker for the management of hypertension and angina pectoris.
EnoximoneA selective phosphodiesterase inhibitor indicated in the short term treatment of congestive heart failure.
NesiritideA recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.
ClevidipineA dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
DesmoteplaseInvestigated for use/treatment in cerebral ischemia and strokes.
DefibrotideA mixture of single-stranded oligonucleotides used in the treatment of severe hepatic veno-occlusive disease with renal or pulmonary dysfunction following hematopoietic stem-cell transplantation.
LofexidineA centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
AzimilideInvestigated for use/treatment in arrhythmia and atrial fibrillation.
AncrodAn anticoagulant purified from the venom of the Malayan pit viper that functions by inactivating circulating plasma fibrinogen. Not currently approved for use or marketed in any country.
BeraprostFor the treatment of pulmonary hypertension.
TetrodotoxinFor the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
FibrinolysinFibrinolysin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas.
IbudilastFor the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
CanertinibInvestigated for use/treatment in breast cancer and lung cancer.
OglufanideInvestigated for use/treatment in hepatitis (viral, C).
TedisamilInvestigated for use/treatment in arrhythmia, atrial fibrillation, and angina.
SulodexideA drug used to treat chronic venous ulcers in the legs.
SemuloparinInvestigated for use/treatment in thrombosis.
AR-9281Investigated for use/treatment in hypertension.
Calcitonin gene-related peptideInvestigated for use/treatment in myocardial infarction, heart disease, and asthma.
AmbrisentanA selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
DexanabinolInvestigated for use/treatment in traumatic brain injuries and neurologic disorders.
DiethylnorspermineInvestigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer.
DotarizineA calcium antagonist used to treat and prevent migraines.
CariporideInvestigated for use/treatment in cardiac surgery.
TezosentanInvestigated for use/treatment in congestive heart failure, liver disease, and heart disease.
DalfampridineA potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS).
NaproxcinodInvestigated for use/treatment in pain (acute or chronic), inflammatory disorders (unspecified), osteoarthritis, and arthritis and arthritic pain.
Ethanolamine oleateA mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes.
NilvadipineA calcium channel blocker used to manage arterial hypertension.
SparteineSparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category...
DanaparoidA heparinoid with anticoagulant and antithrombotic activities used for the treatment of acute episode of Heparin-Induced Thrombocytopenia (HIT), and for prophylaxis in patients with a history of HIT.
DalteparinA low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
Ferulic acidNot Available
FasudilFasudil has been investigated in Carotid Stenosis.
Y-27632Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
BupranololUsed to manage hypertension and tachycardia. Also used to treat glaucoma.
NadroparinA low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
TemocaprilTemocapril is an ACE inhibitor primarily indicated in the treatment of hypertension and congestive heart failure, diabetic nephropathy, and improvement of prognosis for coronary artery diseases (including acute myocardial infarction).
TetraethylammoniumTetraethylammonium is an experimental drug with no approved indication.
IsoxsuprineA beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
Inositol nicotinateA vasodilator and source of niacin found in dietary supplements.
IndoraminIndoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
IndenololIndenolol is a drug of the beta-adrenergic blocker class.
IfenprodilN-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer...
HexamethoniumA nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been...
FendilineFendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
EtilefrineAn adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive.
EperisoneAn antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles.
BatroxobinNo approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously.
TiboloneFor the relief of post-menopausal symptoms and for the prevention of osteoporosis .
PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
XanthinolA vasodilatory niacin found in diet supplements.
CirazolineCirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed...
SynephrineSynephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer...
MoxisylyteBy the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either by...
TrimazosinTrimazosin is a sympatholytic alpha blocker.
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
NicorandilA vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina.
BarnidipineA calcium channel blocker used to treat various forms of hypertension.
BenidipineA synthetic dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris.
CilnidipineA dihydropyridine calcium channel blocker with action on both N- and L-type calcium channels used to treat hypertension.
DarodipineDarodipine is a calcium channel blocker.
EfonidipineFor the treatment of hypertension.
LacidipineA lipophilic dihydropyridine calcium channel blocker with a slow onset of action used to treat hypertension.
NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
NiludipineNiludipine is a calcium channel blocker.
MoxonidineAn imidazoline/α-2 receptor agonist used to treat hypertension, especially in cases where ACE inhibitors, β-blockers, calcium channel blockers, and thiazides are not appropriate or provide inadequate blood pressure control.
ReviparinBy the FDA, reviparin is indicated for the treatment of deep vein which may lead to pulmonary embolism in pediatric patients. It is also indicated for the long-term treatment of...
ParnaparinA low molecular weight heparin (LMWH) used to prevent blood clots, specifically deep vein thrombosis.
MolsidomineA long-acting vasodilator used to treat angina pectoris, including in association with left heart failure and acute myocardial infarction.
TrapidilUsed in the treatment of chronic stable angina .
ImolamineImolamine is indicated for the treatment of angina pectoris. The hydrochloride form is used as a local anesthetic.
Angiotensin 1-7TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities.
RilmenidineAn I1-imidazoline receptor agonist used to treat hypertension.
TalinololTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
ImidaprilAn ACE inhibitor used in the treatment of essential hypertension.
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
Angiotensin IIA peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock.
CarboxyamidotriazoleCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
OzagrelOzagrel has been used in trials studying the treatment of Dry Eye Syndromes.
BQ-123BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
VesnarinoneVesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi.
NaftopidilNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
CinepazideCinepazide has been used in trials studying the treatment of Ischemic Stroke.
BradykininBradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
VinpocetineA synthetic derivative of a vinca alkaloid used to treat neurological symptoms of cerebrovascular disease.
SarpogrelateSarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic.
EplivanserinEplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia, and Primary Insomnia, among others.
LandiololAn ultra short-acting selective beta-blocker used for rapid ventricular rate control in cases of supraventricular tachycardia.
SimendanSimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
PuerarinPuerarin has been investigated for the treatment of Alcohol Abuse.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
KetanserinKetanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.
EtripamilEtripamil has been used in trials studying the treatment of Paroxysmal Supraventricular Tachycardia (PSVT).
UrapidilA combination adrenergic antagonist and serotonin agonist given orally for the treatment of essential hypertension and intravenously in hypertensive emergencies.
SpiradolineSpiradoline has been investigated for the basic science of Bipolar Depression.
PilsicainidePilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
MonteplaseMonteplase has been used in trials studying the treatment of Pulmonary Embolism.
BucindololBucindolol has been investigated in Heart Failure.
CicletanineCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
HigenamineHigenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).
GallopamilGallopamil has been used in trials studying the treatment of Asthma.
CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DihydralazineDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
QGC-001QGC001 has been used in trials studying the treatment of Essential Hypertension.
PhosphocreatineA cardioprotective agent indicated for use in cardiac surgery.
BrinaseNot Annotated
BamifyllineA methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm.
BamethanNot Annotated
CymarinNot Annotated
OctopamineOctopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as...
CarbocromenCarbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development .
ProscillaridinProscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,...
DelaprilAn ACE inhibitor indicated in the treatment of essential hypertension.
IbopamineA sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia.
SuloctidilNot Annotated
DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
CibenzolineNot Annotated
VincamineVincamine is a monoterpenoid indole alkaloid obtained from the leaves of Vinca minor with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
DihydroergocryptineA dopamine agonist indicated in the treatment of cerebrovascular diseases and atherosclerosis.
AdrenaloneNot Annotated
OxyfedrineNot Annotated
LinsidomineNot Annotated
MetildigoxinA digitalis glycoside indicated in the treatment of acute and chronic heart failure.
NicofuranoseNot Annotated
EndralazineNot Annotated
CadralazineNot Annotated
OrnipressinNot Annotated
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
OtiloniumA spasmolytic medication used to treat irritable bowel syndrome (IBS).
CloranololNot Annotated
BuflomedilNot Annotated
AngiotensinamideNot Annotated
NizofenoneNot Annotated
PrajmalineNot Annotated
BietaserpineNot Annotated
NaftidrofurylA peripheral vasodilator indicated in the treatment of chronic venous ulcers.
TiracizineNot Annotated
EthacizineNot Annotated
SaruplaseNot Annotated
LorajmineNot Annotated
BunaftineNot Annotated
LorcainideNot Annotated
ButalamineNot Annotated
AcetyldigoxinNot Annotated
DilazepNot Annotated
HydroquinineNot Annotated
TerodilineNot Annotated
CetiedilNot Annotated
PeruvosideNot Annotated
EpanololEpanolol is an beta blocker.
TertatololTertatolol is a beta blocker.
PrenalterolNot Annotated
VinburnineNot Annotated
MuzolimineNot Annotated
XipamideA diuretic indicated in the treatment of edema.
LinopirdineNot Annotated
BufyllineNot Annotated
CaroverineA calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus.
EtafenoneEtafenone is a vasodilator.
CandesartanAn angiotensin-receptor blocker indicated in the treatment of hypertension.
WIN 55212-2WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It...
DexverapamilNot Annotated
EmopamilPrevents renal injury after warm & cold ischemia.
LomerizineLomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated...
TetrandrineNot Annotated
Morrhuic acidMorrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.
TocopherylquinoneNot Annotated
BenazeprilatNot Annotated
FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
RamiprilatThe active metabolite of the prodrug Ramipril.
PerindoprilatThe active metabolite of the prodrug Perindopril.
QuinaprilatThe active metabolite of the prodrug quinapril.
beta-IsosparteineNot Annotated
HydroquinidineA medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm.
SOR-C13SOR-C13 is under investigation in clinical trial NCT01578564 (Safety and Tolerability Study of SOR-C13 in Subjects With Advanced Cancers Commonly Known to Express the TRPV6 Channel).
CilazaprilatNot Annotated
Atrial natriuretic peptideNot Annotated
ButhiazideA diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases.
RaubasineNot Annotated
NifekalantNifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection).
ApinocaltamideApinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
OxymatrineOxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects).
VasomeraNot Available
OlprinoneNot Annotated
TyrosolNot Annotated
EnadolineNot Annotated
Z-160Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.
PlumbaginPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
SKF-96365 free baseSKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.
PACAP38Not Available
DisufentonNot Annotated
AcecainideAcecainide is an investigational anti-arrhythmia drug.
DideoxyadenosineNot Annotated
S-NitrosoglutathioneNot Annotated
BQ-788Not Annotated
BerbamineNot Annotated
Cinnamic acidNot Annotated
Vasoactive intestinal peptideNot Annotated
Drugs & Drug Targets
DrugTargetType
LepirudinProthrombintarget
AlteplaseFibrinogen alpha chaintarget
AlteplasePlasminogentarget
AlteplasePlasminogen activator inhibitor 1target
AlteplaseFibrinogen gamma chaintarget
ReteplaseFibrinogen alpha chaintarget
ReteplasePlasminogentarget
ReteplasePlasminogen activator inhibitor 1target
AnistreplaseFibrinogen alpha chaintarget
AnistreplasePlasminogentarget
AnistreplasePlasminogen activator inhibitor 1target
TenecteplaseUrokinase plasminogen activator surface receptortarget
TenecteplasePlasminogen activator inhibitor 1target
TenecteplaseFibrinogen alpha chaintarget
TenecteplasePlasminogen activator inhibitor 2target
TenecteplaseTetranectintarget
TenecteplaseKeratin, type II cytoskeletal 8target
TenecteplaseAnnexin A2target
TenecteplaseCalreticulintarget
TenecteplaseCalnexintarget
TenecteplaseProlow-density lipoprotein receptor-related protein 1target
TenecteplasePlasminogentarget
DesmopressinVasopressin V1a receptortarget
DesmopressinVasopressin V1b receptortarget
DesmopressinVasopressin V2 receptortarget
DesmopressinProstaglandin G/H synthase 1enzyme
DesmopressinProstaglandin G/H synthase 2enzyme
VasopressinVasopressin V1a receptortarget
VasopressinVasopressin V2 receptortarget
VasopressinVasopressin V1b receptortarget
VasopressinCanalicular multispecific organic anion transporter 1transporter
VasopressinOxytocin receptortarget
ValsartanType-1 angiotensin II receptortarget
ValsartanCytochrome P450 2C9enzyme
ValsartanSolute carrier organic anion transporter family member 1B3transporter
ValsartanSolute carrier organic anion transporter family member 1B1transporter
ValsartanCanalicular multispecific organic anion transporter 1transporter
RamiprilAngiotensin-converting enzymetarget
RamiprilSolute carrier family 15 member 1transporter
RamiprilSolute carrier family 15 member 2transporter
RamiprilCholinesteraseenzyme
RamiprilB1 bradykinin receptortarget
BetaxololBeta-1 adrenergic receptortarget
BetaxololBeta-2 adrenergic receptortarget
BetaxololCytochrome P450 1A2enzyme
BetaxololCytochrome P450 2D6enzyme
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
SildenafilOrnithine decarboxylasetarget
SildenafilProgrammed cell death 1 ligand 1target
TiclopidineP2Y purinoceptor 12target
TiclopidineCytochrome P450 2C19enzyme
TiclopidineCytochrome P450 2B6enzyme
TiclopidineCytochrome P450 2C9enzyme
TiclopidineCytochrome P450 2D6enzyme
TiclopidineMyeloperoxidaseenzyme
TiclopidineCytochrome P450 1A2enzyme
TiclopidineCytochrome P450 2C8enzyme
TiclopidineCytochrome P450 2E1enzyme
MidodrineAlpha-1A adrenergic receptortarget
MidodrineAlpha-1B adrenergic receptortarget
MidodrineCytochrome P450 2D6enzyme
MidodrineSolute carrier family 15 member 1transporter
MidodrineAlpha-1D adrenergic receptortarget
TorasemideSolute carrier family 12 member 1target
TorasemideCytochrome P450 2C8enzyme
TorasemideCytochrome P450 2C9enzyme
TorasemideSolute carrier organic anion transporter family member 1B1transporter
TorasemideSolute carrier family 12 member 2target
TorasemideSerum albumincarrier
BethanidineAlpha-2 adrenergic receptorstarget
BethanidineATP-sensitive inward rectifier potassium channel 1target
BethanidineBeta adrenergic receptortarget
GlimepirideATP-sensitive inward rectifier potassium channel 1target
GlimepirideATP-sensitive inward rectifier potassium channel 11target
GlimepirideCytochrome P450 2C9enzyme
GlimepirideATP-binding cassette sub-family C member 8target
GlimepirideBile salt export pumptransporter
GuanadrelSodium-dependent noradrenaline transportertarget
MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
RanolazineCytochrome P450 3A4enzyme
RanolazineCytochrome P450 2D6enzyme
RanolazineBile salt export pumptransporter
RanolazineP-glycoprotein 1transporter
RanolazineSodium channel proteintarget
RanolazineInward rectifier potassium channeltarget
RanolazineVoltage gated L-type calcium channeltarget
RanolazineAlpha-1 adrenergic receptorstarget
RanolazineBeta-1 adrenergic receptortarget
RanolazineFatty acidtarget
RanolazineAlpha-1-acid glycoprotein 1carrier
RanolazineMultidrug and toxin extrusion protein 1transporter
RanolazineMultidrug and toxin extrusion protein 2transporter
Methysergide5-hydroxytryptamine receptor 2Atarget
Methysergide5-hydroxytryptamine receptor 1Atarget
Methysergide5-hydroxytryptamine receptor 7target
Methysergide5-hydroxytryptamine receptor 2Ctarget
Methysergide5-hydroxytryptamine receptor 2Btarget
Methysergide5-hydroxytryptamine receptor 1Btarget
Methysergide5-hydroxytryptamine receptor 1Ftarget
Methysergide5-hydroxytryptamine receptor 1Etarget
MethysergideCytochrome P450 3A4enzyme
AnagrelidecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AnagrelideCytochrome P450 1A2enzyme
MetoprololBeta-1 adrenergic receptortarget
MetoprololCytochrome P450 2D6enzyme
MetoprololBeta-2 adrenergic receptortarget
MetoprololSolute carrier family 22 member 2transporter
MetoprololSerum albumincarrier
MetoprololCytochrome P450 3A4enzyme
MetoprololBeta adrenergic receptortarget
OlmesartanType-1 angiotensin II receptortarget
OlmesartanCanalicular multispecific organic anion transporter 1transporter
OlmesartanSolute carrier organic anion transporter family member 1B3transporter
OlmesartanSolute carrier organic anion transporter family member 1B1transporter
OlmesartanBile salt export pumptransporter
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
DisopyramideSodium channel protein type 5 subunit alphatarget
DisopyramideAlpha-1-acid glycoprotein 1carrier
DisopyramideCytochrome P450 3A4enzyme
DisopyramideMuscarinic acetylcholine receptor M1target
DisopyramideMuscarinic acetylcholine receptor M2target
DisopyramideMuscarinic acetylcholine receptor M3target
DisopyramidePotassium voltage-gated channel subfamily D member 2target
DisopyramidePotassium voltage-gated channel subfamily D member 3target
DisopyramideSolute carrier family 22 member 2transporter
DisopyramideSolute carrier family 22 member 1transporter
DisopyramidePotassium voltage-gated channel subfamily H member 2target
DisopyramideAlpha-1-acid glycoprotein 2target
DisopyramideCytochrome P450 1A2enzyme
LidocaineSodium channel protein type 5 subunit alphatarget
LidocaineSodium channel protein type 10 subunit alphatarget
LidocaineEpidermal growth factor receptortarget
LidocaineSodium channel protein type 9 subunit alphatarget
LidocaineCytochrome P450 1A2enzyme
LidocaineCytochrome P450 2D6enzyme
LidocaineCytochrome P450 3A4enzyme
LidocaineCytochrome P450 3A5enzyme
LidocaineCytochrome P450 3A7enzyme
LidocaineSolute carrier family 22 member 5transporter
LidocaineP-glycoprotein 1transporter
LidocaineCytochrome P450 2A6enzyme
LidocaineCytochrome P450 2B6enzyme
LidocaineCytochrome P450 2C8enzyme
LidocaineCytochrome P450 2C9enzyme
LidocaineSodium channel protein type 4 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 1target
LidocaineAlpha-1-acid glycoprotein 2target
IbutilidePotassium voltage-gated channel subfamily H member 6target
IbutilideVoltage-dependent L-type calcium channel subunit beta-1target
IbutilideVoltage-dependent calcium channel gamma-1 subunittarget
IbutilideVoltage-dependent calcium channel subunit alpha-2/delta-1target
IbutilidePotassium voltage-gated channel subfamily H member 2target
IbutilideVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IbutilidePotassium channel subfamily K member 1target
IbutilidePotassium channel subfamily K member 6target
IbutilideATP-sensitive inward rectifier potassium channel 11target
IbutilidePotassium voltage-gated channel subfamily H member 7target
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DihydroergotamineCytochrome P450 3A4enzyme
DihydroergotamineAlpha-2A adrenergic receptortarget
Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DihydroergotamineP-glycoprotein 1transporter
Dihydroergotamine5-hydroxytryptamine receptor 1Atarget
Dihydroergotamine5-hydroxytryptamine receptor 1Etarget
Dihydroergotamine5-hydroxytryptamine receptor 2Atarget
Dihydroergotamine5-hydroxytryptamine receptor 2Ctarget
DihydroergotamineAlpha-1 adrenergic receptorstarget
DihydroergotamineAlpha-2 adrenergic receptorstarget
DihydroergotamineDopamine D2 receptortarget
DihydroergotamineDopamine D3 receptortarget
DihydroergotamineDopamine D4 receptortarget
Dihydroergotamine5-hydroxytryptamine receptor 1Ftarget
Dihydroergotamine5-hydroxytryptamine receptor 4target
DihydroergotamineBeta-3 adrenergic receptortarget
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
IndomethacinInterferon-induced, double-stranded RNA-activated protein kinasetarget
IndomethacinHuman Cyclooxygenasestarget
AtenololBeta-1 adrenergic receptortarget
AtenololBeta-2 adrenergic receptortarget
AtenololCytochrome P450 2D6enzyme
AtenololBile salt export pumptransporter
AtenololSerum albumincarrier
DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DiltiazemCytochrome P450 3A4enzyme
DiltiazemCytochrome P450 2C19enzyme
DiltiazemCytochrome P450 2D6enzyme
DiltiazemCytochrome P450 3A5enzyme
DiltiazemCytochrome P450 3A7enzyme
DiltiazemP-glycoprotein 1transporter
DiltiazemCytochrome P450 2C8enzyme
DiltiazemSerum albumincarrier
DiltiazemAlpha-1-acid glycoprotein 1carrier
DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineSolute carrier family 22 member 5transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
TimololBeta-1 adrenergic receptortarget
TimololBeta-2 adrenergic receptortarget
TimololCytochrome P450 2D6enzyme
TimololP-glycoprotein 1transporter
TimololCytochrome P450 2C19enzyme
TimololLysozymetarget
AmlodipineCarbonic anhydrase 1target
AmlodipineCytochrome P450 3A4enzyme
AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AmlodipineCytochrome P450 1A1enzyme
AmlodipineCytochrome P450 2B6enzyme
AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
AmlodipineCytochrome P450 3A5enzyme
AmlodipineP-glycoprotein 1transporter
AmlodipineCytochrome P450 2C8enzyme
AmlodipineCytochrome P450 2D6enzyme
AmlodipineSphingomyelin phosphodiesterasetarget
AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmlodipineVoltage-dependent N-type calcium channeltarget
AmlodipineCytochrome P450 2C19enzyme
AmlodipineCytochrome P450 2C9enzyme
TriamtereneAmiloride-sensitive sodium channel subunit gammatarget
TriamtereneAmiloride-sensitive sodium channel subunit alphatarget
TriamtereneAmiloride-sensitive sodium channel subunit betatarget
TriamtereneAmiloride-sensitive sodium channel subunit deltatarget
TriamtereneCytochrome P450 1A2enzyme
PhenylephrineAlpha-1A adrenergic receptortarget
PhenylephrineAlpha-1B adrenergic receptortarget
PhenylephrineAmine oxidase [flavin-containing] Aenzyme
PhenylephrineAlpha-1D adrenergic receptortarget
PhenylephrineCytochrome P450 1A2enzyme
PhenylephrineSulfotransferase 1A3/1A4enzyme
PhenylephrineAmine oxidase [flavin-containing] Benzyme
DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigoxinP-glycoprotein 1transporter
DigoxinSolute carrier organic anion transporter family member 4C1transporter
DigoxinBile salt export pumptransporter
DigoxinSolute carrier organic anion transporter family member 1A2transporter
DigoxinOrganic solute transporter subunit alphatransporter
DigoxinOrganic solute transporter subunit betatransporter
DigoxinSolute carrier organic anion transporter family member 1B1transporter
NimodipineCytochrome P450 3A4enzyme
NimodipineMineralocorticoid receptortarget
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NimodipineVoltage-dependent L-type calcium channel subunit beta-2target
NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
NimodipineVoltage-dependent L-type calcium channel subunit beta-1target
NimodipineVoltage-dependent L-type calcium channel subunit beta-3target
NimodipineVoltage-dependent L-type calcium channel subunit beta-4target
NimodipineAryl hydrocarbon receptortarget
NisoldipineCytochrome P450 3A4enzyme
NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NisoldipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NisoldipineVoltage-dependent L-type calcium channel subunit beta-2target
NisoldipineCytochrome P450 3A5enzyme
NisoldipineCytochrome P450 3A7enzyme
NisoldipineP-glycoprotein 1transporter
CarbamoylcholineMuscarinic acetylcholine receptor M1target
CarbamoylcholineMuscarinic acetylcholine receptor M2target
CarbamoylcholineNeuronal acetylcholine receptor subunit alpha-2target
CarbamoylcholineCytosolic phospholipase A2enzyme
CarbamoylcholineMuscarinic acetylcholine receptor M3target
CarbamoylcholineMuscarinic acetylcholine receptor M4target
CarbamoylcholineAcetylcholinesteraseenzyme
SpironolactoneMineralocorticoid receptortarget
SpironolactoneCytochrome P450 2C8enzyme
SpironolactoneCanalicular multispecific organic anion transporter 1transporter
SpironolactoneP-glycoprotein 1transporter
SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
SpironolactoneAndrogen receptortarget
SpironolactoneProgesterone receptortarget
SpironolactoneGlucocorticoid receptortarget
SpironolactoneNuclear receptor subfamily 1 group I member 2target
SpironolactoneBile salt export pumptransporter
SpironolactoneSerum albumincarrier
Spironolactonealpha1-acid glycoproteincarrier
SpironolactoneEstrogen receptortarget
SpironolactoneCytochrome P450 11B2, mitochondrialenzyme
SpironolactoneVoltage-dependent L-type calcium channeltarget
HyoscyamineMuscarinic acetylcholine receptor M1target
HyoscyamineMuscarinic acetylcholine receptor M2target
HyoscyamineMuscarinic acetylcholine receptor M3target
HyoscyamineMuscarinic acetylcholine receptor M4target
HyoscyamineAdenylate cyclase type 1target
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
Nitric OxideNitric oxide synthase, endothelialtarget
BendroflumethiazideSolute carrier family 12 member 3target
BendroflumethiazideCarbonic anhydrase 1target
BendroflumethiazideCarbonic anhydrase 2target
BendroflumethiazideCarbonic anhydrase 4target
BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
BendroflumethiazideThiopurine S-methyltransferaseenzyme
PrazosinAlpha-1A adrenergic receptortarget
PrazosinAlpha-1B adrenergic receptortarget
PrazosinAlpha-1D adrenergic receptortarget
PrazosinPotassium voltage-gated channel subfamily H member 2target
PrazosinAlpha-1-acid glycoprotein 1carrier
PrazosinSolute carrier family 22 member 1transporter
PrazosinSolute carrier family 22 member 3transporter
PrazosinP-glycoprotein 1transporter
PrazosinATP-binding cassette sub-family G member 2transporter
PrazosinAlpha-2A adrenergic receptortarget
PrazosinAlpha-2B adrenergic receptortarget
PrazosinAlpha-1 adrenergic receptorstarget
BrimonidineAlpha-2A adrenergic receptortarget
BrimonidineAlpha-2B adrenergic receptortarget
BrimonidineAlpha-2C adrenergic receptortarget
BrimonidineAldehyde oxidaseenzyme
SotalolPotassium voltage-gated channel subfamily H member 2target
SotalolBeta-1 adrenergic receptortarget
SotalolBeta-2 adrenergic receptortarget
SotalolCytochrome P450 2D6enzyme
FosinoprilAngiotensin-converting enzymetarget
FosinoprilSolute carrier family 15 member 1transporter
FosinoprilSolute carrier family 15 member 2transporter
AcetyldigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
TrandolaprilAngiotensin-converting enzymetarget
TrandolaprilSolute carrier family 15 member 1transporter
TrandolaprilSolute carrier family 15 member 2transporter
TrandolaprilLiver carboxylesterase 1enzyme
CarteololBeta-2 adrenergic receptortarget
CarteololBeta-1 adrenergic receptortarget
CarteololCytochrome P450 2D6enzyme
MetolazoneSolute carrier family 12 member 3target
LercanidipineVoltage-dependent calcium channel gamma-1 subunittarget
LercanidipineCytochrome P450 3A4enzyme
LercanidipineCytochrome P450 3A5enzyme
LercanidipineCytochrome P450 3A7enzyme
LercanidipineCytochrome P450 2D6enzyme
BenazeprilAngiotensin-converting enzymetarget
BenazeprilMethylenetetrahydrofolate reductaseenzyme
BenazeprilSolute carrier family 15 member 1transporter
BenazeprilSolute carrier family 15 member 2transporter
PropranololBeta-1 adrenergic receptortarget
PropranololBeta-2 adrenergic receptortarget
PropranololBeta-3 adrenergic receptortarget
Propranolol5-hydroxytryptamine receptor 1Atarget
Propranolol5-hydroxytryptamine receptor 1Btarget
PropranololCytochrome P450 1A2enzyme
PropranololCytochrome P450 2D6enzyme
PropranololAlpha-1-acid glycoprotein 1carrier
PropranololCytochrome P450 2C19enzyme
PropranololCytochrome P450 3A4enzyme
PropranololCytochrome P450 3A5enzyme
PropranololCytochrome P450 3A7enzyme
PropranololSolute carrier family 22 member 2transporter
PropranololP-glycoprotein 1transporter
PropranololCytochrome P450 1A1enzyme
PropranololAmine oxidase [flavin-containing] Aenzyme
PropranololSerum albumincarrier
AtropineMuscarinic acetylcholine receptor M2target
AtropineMuscarinic acetylcholine receptor M1target
AtropineMuscarinic acetylcholine receptor M4target
AtropineMuscarinic acetylcholine receptor M5target
AtropineMuscarinic acetylcholine receptor M3target
AtropineGlycine receptor subunit alpha-1target
AtropineNeuronal acetylcholine receptor subunit alpha-4target
AtropineNeuronal acetylcholine receptor subunit beta-2target
AtropineBile salt export pumptransporter
AtropineAlpha-1-acid glycoprotein 1carrier
ClonidineAlpha-2A adrenergic receptortarget
ClonidineCytochrome P450 2D6enzyme
ClonidineAlpha-2B adrenergic receptortarget
ClonidineAlpha-2C adrenergic receptortarget
ClonidineSolute carrier family 22 member 3transporter
ClonidineSolute carrier family 22 member 5transporter
ClonidineSolute carrier family 22 member 4transporter
ClonidineCytochrome P450 1A2enzyme
ClonidineCytochrome P450 3A4enzyme
ClonidineCytochrome P450 1A1enzyme
ClonidineCytochrome P450 3A5enzyme
ClonidineAlpha-1A adrenergic receptortarget
ClonidineAlpha-1B adrenergic receptortarget
ClonidineAlpha-1D adrenergic receptortarget
ClonidineSerum albumincarrier
EnalaprilAngiotensin-converting enzymetarget
EnalaprilP-glycoprotein 1transporter
EnalaprilSolute carrier family 15 member 1transporter
EnalaprilSolute carrier family 22 member 6transporter
EnalaprilSolute carrier family 22 member 8transporter
EnalaprilSolute carrier family 22 member 7transporter
EnalaprilSolute carrier organic anion transporter family member 1A2transporter
EnalaprilSerum albumincarrier
DoxazosinAlpha-1A adrenergic receptortarget
DoxazosinAlpha-1D adrenergic receptortarget
DoxazosinHERG human cardiac K+ channeltarget
DoxazosinP-glycoprotein 1transporter
DoxazosinCytochrome P450 2C19enzyme
DoxazosinCytochrome P450 2D6enzyme
DoxazosinSolute carrier family 22 member 1transporter
DoxazosinCytochrome P450 3A4enzyme
DoxazosinAlpha-1B adrenergic receptortarget
DoxazosinCytochrome P450 2C9enzyme
AmilorideAmiloride-sensitive sodium channel subunit betatarget
AmilorideAcid-sensing ion channel 1target
AmilorideAmiloride-sensitive amine oxidase [copper-containing]target
AmilorideAmiloride-sensitive sodium channel subunit alphatarget
AmilorideAmiloride-sensitive sodium channel subunit gammatarget
AmilorideSodium/hydrogen exchanger 1target
AmilorideAcid-sensing ion channel 2target
AmilorideAmiloride-sensitive sodium channel subunit deltatarget
AmilorideUrokinase-type plasminogen activatortarget
AmilorideSolute carrier family 22 member 2transporter
AmilorideSolute carrier family 22 member 4transporter
AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
UlobetasolCorticosteroid-binding globulincarrier
UlobetasolGlucocorticoid receptortarget
LabetalolAlpha-1 adrenergic receptorstarget
LabetalolBeta-1 adrenergic receptortarget
LabetalolBeta-2 adrenergic receptortarget
LabetalolCytochrome P450 2D6enzyme
LabetalolCytochrome P450 2C19enzyme
LabetalolSerum albumincarrier
Labetalolalpha1-acid glycoproteincarrier
LabetalolATP-binding cassette sub-family B member 5transporter
LabetalolUDP-glucuronosyltransferase 1-1enzyme
LabetalolUDP-glucuronosyltransferase 2B7enzyme
LabetalolUDP-glucuronosyltransferase 1-9enzyme
CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
CyclothiazideCarbonic anhydrase 1target
CyclothiazideCarbonic anhydrase 2target
CyclothiazideSolute carrier family 22 member 6transporter
CyclothiazideSecreted frizzled-related protein 4target
CyclothiazideCarbonic anhydrasetarget
BisoprololBeta-1 adrenergic receptortarget
BisoprololBeta-2 adrenergic receptortarget
BisoprololCytochrome P450 3A4enzyme
BisoprololP-glycoprotein 1transporter
NiacinHydroxycarboxylic acid receptor 2target
NiacinNicotinamide N-methyltransferasetarget
NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
NiacinHydroxycarboxylic acid receptor 3target
NiacinSolute carrier family 22 member 5transporter
NiacinSolute carrier organic anion transporter family member 2B1transporter
NiacinMonocarboxylate transporter 1transporter
NiacinCytochrome P450 2D6enzyme
NiacinSodium-coupled monocarboxylate transporter 1transporter
NiacinMonocarboxylate transporter 4transporter
NiacinThyroxine-binding globulincarrier
NiacinCytochrome P450 3A4enzyme
NiacinCytochrome P450 2E1enzyme
AdenosineAdenosine receptor A3target
AdenosineAdenosine deaminaseenzyme
AdenosineAdenosine kinaseenzyme
AdenosineAdenosine receptor A1target
AdenosineAdenosine receptor A2atarget
AdenosineAdenosine receptor A2btarget
AdenosineSolute carrier family 28 member 3transporter
AdenosineEquilibrative nucleoside transporter 1transporter
AdenosineEquilibrative nucleoside transporter 2transporter
AdenosineEquilibrative nucleoside transporter 3transporter
AdenosineEquilibrative nucleoside transporter 4transporter
AdenosineSodium/nucleoside cotransporter 1transporter
AdenosineSodium/nucleoside cotransporter 2transporter
AdenosineGap junction alpha-1 proteintransporter
AdenosineAdenylate kinase isoenzyme 1enzyme
AdenosineNucleoside diphosphate kinase Aenzyme
AdenosineNucleoside diphosphate kinase Benzyme
AdenosinePurine nucleoside phosphorylaseenzyme
AdenosineXanthine dehydrogenase/oxidaseenzyme
AdenosineSerum albumincarrier
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DyphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DyphyllineAdenosine receptor A1target
DyphyllineAdenosine receptor A2atarget
VerapamilATP-sensitive inward rectifier potassium channel 11target
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
VerapamilPotassium voltage-gated channel subfamily H member 2target
VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
VerapamilCytochrome P450 1A2enzyme
VerapamilCytochrome P450 3A5enzyme
VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
VerapamilSodium-dependent serotonin transportertarget
VerapamilCytochrome P450 3A4enzyme
VerapamilP-glycoprotein 1transporter
VerapamilSolute carrier family 22 member 1transporter
VerapamilCanalicular multispecific organic anion transporter 2transporter
VerapamilMultidrug resistance-associated protein 4transporter
VerapamilSolute carrier family 22 member 5transporter
VerapamilSolute carrier organic anion transporter family member 1A2transporter
VerapamilMultidrug resistance-associated protein 7transporter
VerapamilSolute carrier family 22 member 4transporter
VerapamilSolute carrier organic anion transporter family member 1B1transporter
VerapamilCytochrome P450 2C8enzyme
VerapamilCytochrome P450 2C9enzyme
VerapamilCytochrome P450 2B6enzyme
VerapamilCytochrome P450 2C19enzyme
VerapamilCytochrome P450 2D6enzyme
VerapamilAlpha-1A adrenergic receptortarget
VerapamilAlpha-1B adrenergic receptortarget
VerapamilAlpha-1D adrenergic receptortarget
VerapamilSerum albumincarrier
VerapamilAlpha-1-acid glycoprotein 1carrier
VerapamilCytochrome P450 2C18enzyme
VerapamilCytochrome P450 2E1enzyme
VerapamilMultidrug resistance-associated protein 1transporter
VerapamilMultidrug and toxin extrusion protein 1transporter
VerapamilMultidrug and toxin extrusion protein 2transporter
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
VerapamilVoltage-dependent calcium channeltarget
VerapamilP-glycoprotein 1target
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
Sumatriptan5-hydroxytryptamine receptor 1Dtarget
Sumatriptan5-hydroxytryptamine receptor 1Btarget
Sumatriptan5-hydroxytryptamine receptor 1Ftarget
SumatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Atarget
SumatriptanSolute carrier organic anion transporter family member 1A2transporter
SumatriptanP-glycoprotein 1transporter
SumatriptanATP-binding cassette sub-family G member 2transporter
SumatriptanSolute carrier organic anion transporter family member 1B1transporter
LosartanType-1 angiotensin II receptortarget
LosartanCytochrome P450 3A4enzyme
LosartanCytochrome P450 2C9enzyme
LosartanP-glycoprotein 1transporter
LosartanSolute carrier family 22 member 6transporter
LosartanUDP-glucuronosyltransferase 1-1enzyme
LosartanUDP-glucuronosyltransferase 1-3enzyme
LosartanUDP-glucuronosyltransferase 1-10enzyme
LosartanUDP-glucuronosyltransferase 2B7enzyme
LosartanUDP-glucuronosyltransferase 2B17enzyme
LosartanCytochrome P450 2C19enzyme
LosartanSerum albumincarrier
LosartanSolute carrier family 22 member 12transporter
LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
LosartanBile salt export pumptransporter
LosartanCytochrome P450 2C8enzyme
MoexiprilAngiotensin-converting enzymetarget
MoexiprilSolute carrier family 15 member 1transporter
MoexiprilSolute carrier family 15 member 2transporter
PhentolamineAlpha-1 adrenergic receptorstarget
PhentolamineAlpha-2 adrenergic receptorstarget
PhentolamineATP-sensitive inward rectifier potassium channel 11target
FurosemideSolute carrier family 12 member 1target
FurosemideSerum albumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideSolute carrier family 22 member 5transporter
FurosemideSolute carrier family 22 member 8transporter
FurosemideCanalicular multispecific organic anion transporter 1transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1-1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
ErgotamineAlpha-1A adrenergic receptortarget
Ergotamine5-hydroxytryptamine receptor 1Dtarget
Ergotamine5-hydroxytryptamine receptor 1Btarget
Ergotamine5-hydroxytryptamine receptor 2Atarget
ErgotamineAlpha-2A adrenergic receptortarget
ErgotamineDopamine D2 receptortarget
ErgotamineCytochrome P450 3A4enzyme
ErgotamineAlpha-1B adrenergic receptortarget
ErgotamineAlpha-1D adrenergic receptortarget
ErgotamineP-glycoprotein 1transporter
ErgotamineD(1) dopamine receptortarget
Ergotamine5-hydroxytryptamine receptor 1Atarget
Ergotamine5-hydroxytryptamine receptor 1Ftarget
Ergotamine5-hydroxytryptamine receptor 2Ctarget
Ergotamine5-hydroxytryptamine receptor 2Btarget
ErgotamineAlpha-2C adrenergic receptortarget
EplerenoneMineralocorticoid receptortarget
EplerenoneCytochrome P450 3A4enzyme
EplerenoneCytochrome P450 3A5enzyme
EplerenoneCytochrome P450 11B2, mitochondrialenzyme
MethazolamideCarbonic anhydrase 1target
MethazolamideSolute carrier family 22 member 6transporter
MethazolamideCarbonic anhydrase 4target
MethazolamideCarbonic anhydrase 2target
MethazolamideCarbonic anhydrase 7target
MethazolamideCarbonic anhydrase 3target
LisinoprilAngiotensin-converting enzymetarget
LisinoprilSolute carrier family 15 member 1transporter
LisinoprilSolute carrier family 15 member 2transporter
LisinoprilRenintarget
NitroglycerinAtrial natriuretic peptide receptor 1target
NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
TirofibanIntegrin alpha-IIbtarget
TirofibanIntegrin beta-3target
CryptenamineMuscarinic acetylcholine receptor M2target
CryptenamineBeta adrenergic receptortarget
PerindoprilAngiotensin-converting enzymetarget
PerindoprilSolute carrier family 15 member 1transporter
PerindoprilSolute carrier family 15 member 2transporter
PerindoprilCholinesteraseenzyme
PerindoprilSecreted frizzled-related protein 4target
Candesartan cilexetilType-1 angiotensin II receptortarget
Candesartan cilexetilCytochrome P450 2C8enzyme
Candesartan cilexetilCytochrome P450 2C9enzyme
Candesartan cilexetilP-glycoprotein 1transporter
Candesartan cilexetilUDP-glucuronosyltransferase 1-3enzyme
Candesartan cilexetilProstaglandin G/H synthase 1enzyme
TolazolineAlpha-1A adrenergic receptortarget
TolazolineAlpha-2A adrenergic receptortarget
TolazolineHistamine H1 receptortarget
TolazolineHistamine H2 receptortarget
TolazolineAlpha-2C adrenergic receptortarget
TolazolineAlpha-2B adrenergic receptortarget
FenoldopamDopamine D5 receptortarget
FenoldopamDopamine D1 receptortarget
FenoldopamAlpha-2B adrenergic receptortarget
FenoldopamAlpha-2C adrenergic receptortarget
FenoldopamAlpha-2A adrenergic receptortarget
FenoldopamAlpha-1B adrenergic receptortarget
FenoldopamAlpha-1D adrenergic receptortarget
FenoldopamAlpha-1A adrenergic receptortarget
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
IndapamideEpoxide hydrolase 1enzyme
Indapamidealpha1-acid glycoproteincarrier
IndapamideSerum albumincarrier
IndapamideErythrocytecarrier
AcetazolamideCarbonic anhydrase 1target
AcetazolamideAquaporin-1target
AcetazolamideCarbonic anhydrase 14target
AcetazolamideSolute carrier family 22 member 6transporter
AcetazolamideCarbonic anhydrase 2target
AcetazolamideCarbonic anhydrase 3target
AcetazolamideCarbonic anhydrase 4target
AcetazolamideCytochrome P450 3A4enzyme
AcetazolamideCarbonic anhydrase 7target
AcetazolamideCarbonic anhydrase 12target
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
DobutamineBeta-1 adrenergic receptortarget
DobutamineCatechol O-methyltransferaseenzyme
DobutamineBeta-2 adrenergic receptortarget
DobutamineAlpha-1 adrenergic receptorstarget
DobutamineEstrogen receptor alphatarget
PseudoephedrineAlpha-1A adrenergic receptortarget
PseudoephedrineAlpha-2A adrenergic receptortarget
PseudoephedrineBeta-2 adrenergic receptortarget
PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
PseudoephedrineBeta-1 adrenergic receptortarget
PseudoephedrineSodium-dependent dopamine transportertarget
PseudoephedrineSodium-dependent noradrenaline transportertarget
PseudoephedrineSodium-dependent serotonin transportertarget
PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
PseudoephedrineTumor necrosis factortarget
PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
Pseudoephedrineactivator protein 1target
PseudoephedrineInterleukin-2target
PseudoephedrineSerum albumincarrier
PseudoephedrineSodium-dependent noradrenaline transportertransporter
PseudoephedrineSodium-dependent dopamine transportertransporter
PseudoephedrineSodium-dependent serotonin transportertransporter
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
VardenafilCytochrome P450 2C9enzyme
VardenafilCytochrome P450 2C8enzyme
VardenafilCytochrome P450 2C19enzyme
VardenafilCytochrome P450 2D6enzyme
AlprenololBeta-1 adrenergic receptortarget
AlprenololBeta-2 adrenergic receptortarget
Alprenolol5-hydroxytryptamine receptor 1Atarget
AlprenololCytochrome P450 2D6enzyme
AlprenololBeta-3 adrenergic receptortarget
DorzolamideCarbonic anhydrase 2target
DorzolamideCarbonic anhydrase 1target
DorzolamideCarbonic anhydrase 4target
DorzolamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 3target
DorzolamideCytochrome P450 2B1enzyme
DorzolamideCytochrome P450 2E1enzyme
DorzolamideCytochrome P450 3A2enzyme
EprosartanType-1 angiotensin II receptortarget
EprosartanCanalicular multispecific organic anion transporter 1transporter
ChlorothiazideSolute carrier family 12 member 3target
ChlorothiazideCarbonic anhydrase 1target
ChlorothiazideCarbonic anhydrase 2target
ChlorothiazideSolute carrier family 22 member 6transporter
QuinaprilAngiotensin-converting enzymetarget
QuinaprilSolute carrier family 15 member 1transporter
QuinaprilSolute carrier family 15 member 2transporter
QuinaprilSolute carrier family 22 member 8transporter
QuinaprilLiver carboxylesterase 1enzyme
QuinaprilSerum albumincarrier
Risedronic acidFarnesyl pyrophosphate synthasetarget
Risedronic acidHydroxylapatitetarget
Risedronic acidProstaglandin G/H synthase 2enzyme
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
BimatoprostProstaglandin F2-alpha receptortarget
BimatoprostProstaglandin E2 receptor EP1 subtypetarget
BimatoprostProstaglandin E2 receptor EP3 subtypetarget
BimatoprostCytochrome P450 3A4enzyme
BimatoprostCytochrome P450 3A5enzyme
CocaineSodium-dependent noradrenaline transportertarget
CocaineSodium channel proteintarget
CocaineSodium-dependent serotonin transportertarget
CocaineSodium-dependent dopamine transportertarget
CocaineCytochrome P450 3A4enzyme
CocaineMuscarinic acetylcholine receptor M1target
CocaineMuscarinic acetylcholine receptor M2target
CocaineCytochrome P450 2D6enzyme
CocaineSolute carrier family 22 member 2transporter
CocaineCytochrome P450 2C8enzyme
CocaineSigma non-opioid intracellular receptor 1target
CocaineLiver carboxylesterase 1target
CocaineCholinesteraseenzyme
CocaineSodium-dependent dopamine transportertransporter
Cocainealpha1-acid glycoproteincarrier
CocaineLiver carboxylesterase 1enzyme
PhenoxybenzamineAlpha-1A adrenergic receptortarget
PhenoxybenzamineCalmodulintarget
PhenoxybenzamineSolute carrier family 22 member 2transporter
PhenoxybenzamineSolute carrier family 22 member 1transporter
PhenoxybenzamineSolute carrier family 22 member 3transporter
PhenoxybenzamineAlpha-2A adrenergic receptortarget
PhenoxybenzamineAlpha-2C adrenergic receptortarget
PhenoxybenzamineAlpha-2B adrenergic receptortarget
PhenoxybenzamineBeta-2 adrenergic receptortarget
PhenoxybenzamineAlpha-1B adrenergic receptortarget
PhenoxybenzamineAlpha-1D adrenergic receptortarget
OxymetazolineAlpha-1A adrenergic receptortarget
OxymetazolineAlpha-2A adrenergic receptortarget
OxymetazolineAlpha-2C adrenergic receptortarget
OxymetazolineAlpha-2B adrenergic receptortarget
OxymetazolineAlpha-1B adrenergic receptortarget
OxymetazolineAlpha-1D adrenergic receptortarget
Oxymetazoline5-hydroxytryptamine receptor 1Atarget
Oxymetazoline5-hydroxytryptamine receptor 1Btarget
Oxymetazoline5-hydroxytryptamine receptor 1Dtarget
Oxymetazoline5-hydroxytryptamine receptor 1Ctarget
OxymetazolineUDP-glucuronosyltransferase 1-9enzyme
OxymetazolineCytochrome P450 2C19enzyme
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
Acetylsalicylic acidSialidase-1target
PindololBeta-1 adrenergic receptortarget
PindololBeta-2 adrenergic receptortarget
Pindolol5-hydroxytryptamine receptor 1Atarget
Pindolol5-hydroxytryptamine receptor 1Btarget
PindololCytochrome P450 2D6enzyme
PindololBeta-3 adrenergic receptortarget
PindololUDP-glucuronosyltransferases (UGTs)enzyme
PindololSulfotransferaseenzyme
PindololSolute carrier family 22 member 2transporter
Pindololalpha1-acid glycoproteincarrier
TelmisartanType-1 angiotensin II receptortarget
TelmisartanPeroxisome proliferator-activated receptor gammatarget
TelmisartanP-glycoprotein 1transporter
TelmisartanCanalicular multispecific organic anion transporter 1transporter
TelmisartanATP-binding cassette sub-family G member 2transporter
TelmisartanCytochrome P450 2C19enzyme
TelmisartanBile salt export pumptransporter
TelmisartanUDP-glucuronosyltransferase 1-3enzyme
MethyldopaAlpha-2A adrenergic receptortarget
MethyldopaCatechol O-methyltransferaseenzyme
MethyldopaSolute carrier family 15 member 1transporter
MethyldopaAromatic-L-amino-acid decarboxylasetarget
MethyldopaSerum albumincarrier
MethyldopaSulfotransferaseenzyme
MethyldopaDopamine beta-hydroxylaseenzyme
MethyldopaPhenylethanolamine N-methyltransferaseenzyme
MethyldopaAromatic-L-amino-acid decarboxylaseenzyme
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
DopamineDopamine D1 receptortarget
DopamineDopamine beta-hydroxylasetarget
DopamineAmine oxidase [flavin-containing] Aenzyme
DopamineAmine oxidase [flavin-containing] Benzyme
DopamineCatechol O-methyltransferaseenzyme
DopamineSolute carrier family 22 member 2transporter
DopamineSolute carrier family 22 member 1transporter
DopamineSolute carrier family 22 member 3transporter
DopamineSolute carrier family 22 member 5transporter
DopaminePOU domain, class 5, transcription factor 1transporter
DopamineDopamine D5 receptortarget
DopamineDopamine D2 receptortarget
DopamineDopamine D3 receptortarget
DopamineDopamine D4 receptortarget
DopamineSodium-dependent dopamine transportertarget
DopamineDopamine beta-hydroxylaseenzyme
Dopamine5-hydroxytryptamine receptor 1Atarget
Dopamine5-hydroxytryptamine receptor 7target
DopamineD(1) dopamine receptortarget
DopamineSodium-dependent noradrenaline transportertarget
DopamineSodium-dependent serotonin transportertarget
Dopamine5-hydroxytryptamine receptor 3Atarget
Dopamine5-hydroxytryptamine receptor 3Btarget
DopamineSuperoxide dismutase [Cu-Zn]target
DopamineSynaptic vesicular amine transportertarget
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
GuanfacineAlpha-2A adrenergic receptortarget
GuanfacineCytochrome P450 2C19enzyme
GuanfacineCytochrome P450 3A4enzyme
GuanfacineAlpha-2B adrenergic receptortarget
GuanfacineMultidrug and toxin extrusion protein 1transporter
GuanfacineSolute carrier family 22 member 1transporter
GuanfacineSolute carrier family 22 member 2transporter
Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
TrichlormethiazideSolute carrier family 12 member 3target
TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
TrichlormethiazideCarbonic anhydrase 4target
TrichlormethiazideCarbonic anhydrase 2target
TrichlormethiazideCarbonic anhydrase 1target
TrichlormethiazideThiopurine S-methyltransferaseenzyme
IrbesartanType-1 angiotensin II receptortarget
IrbesartanTranscription factor AP-1target
IrbesartanCytochrome P450 2C9enzyme
IrbesartanCytochrome P450 2C8enzyme
IrbesartanUDP-glucuronosyltransferase 1-3enzyme
IrbesartanProstaglandin G/H synthase 1enzyme
IrbesartanCytochrome P450 3A4enzyme
IrbesartanSerum albumincarrier
Irbesartanalpha1-acid glycoproteincarrier
ProcainamideSodium channel protein type 5 subunit alphatarget
ProcainamideDNA (cytosine-5)-methyltransferase 1target
ProcainamideCytochrome P450 2D6enzyme
ProcainamideCholinesteraseenzyme
ProcainamideSolute carrier family 22 member 2transporter
ProcainamideSolute carrier family 22 member 1transporter
ProcainamideSolute carrier family 22 member 3transporter
ProcainamideSolute carrier family 22 member 5transporter
ProcainamideSolute carrier family 22 member 4transporter
ProcainamidePotassium voltage-gated channel subfamily H member 2target
ProcainamideMultidrug and toxin extrusion protein 1transporter
ProcainamideMultidrug and toxin extrusion protein 2transporter
Ergoloid mesylateDopamine receptortarget
Ergoloid mesylateAlpha adrenergic receptortarget
Ergoloid mesylateBeta adrenergic receptortarget
Ergoloid mesylateSerotonin Receptorstarget
Ergoloid mesylateCytochrome P450 3A4enzyme
TocainideSodium channel protein type 5 subunit alphatarget
TocainideSerum albumincarrier
TocainideCytochrome P450 1A2enzyme
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineSuperoxide dismutase [Cu-Zn]target
IsoprenalineCytochrome P450 1B1enzyme
IsoprenalineSerum albumincarrier
IsoprenalineCatechol O-methyltransferaseenzyme
IsoprenalineCholinesteraseenzyme
DeslanosideSodium/potassium-transporting ATPase subunit alpha-1target
PentoliniumNeuronal acetylcholine receptor subunit alpha-10target
PentoliniumNeuronal acetylcholine receptor subunit alpha-3target
PentoliniumNeuronal acetylcholine receptor subunit beta-4target
OuabainSodium/potassium-transporting ATPase subunit alpha-1target
OuabainSolute carrier organic anion transporter family member 1A2transporter
OuabainSolute carrier family 22 member 8transporter
OuabainSolute carrier organic anion transporter family member 4C1transporter
OuabainSolute carrier organic anion transporter family member 1B3transporter
OuabainSolute carrier organic anion transporter family member 1C1transporter
OuabainSolute carrier organic anion transporter family member 1B1transporter
OuabainSodium/potassium-transporting ATPase subunit alpha-2target
OuabainSodium/potassium-transporting ATPase subunit alpha-3target
ArbutamineBeta-1 adrenergic receptortarget
ArbutamineBeta-2 adrenergic receptortarget
ArbutamineBeta-3 adrenergic receptortarget
NifedipineCytochrome P450 3A4enzyme
NifedipineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 2D6enzyme
NifedipineCalmodulintarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
NifedipinePotassium voltage-gated channel subfamily D member 3target
NifedipineVoltage-dependent T-type calcium channeltarget
NifedipineCytochrome P450 1A2enzyme
NifedipineCytochrome P450 2A6enzyme
NifedipineCytochrome P450 2C8enzyme
NifedipineCanalicular multispecific organic anion transporter 2transporter
NifedipineP-glycoprotein 1transporter
NifedipineCanalicular multispecific organic anion transporter 1transporter
NifedipineCytochrome P450 1A1enzyme
NifedipineCytochrome P450 2B6enzyme
NifedipineNuclear receptor subfamily 1 group I member 2target
NifedipineSolute carrier organic anion transporter family member 1B1transporter
NifedipineBile salt export pumptransporter
NifedipineCytochrome P450 2C9enzyme
NifedipineSerum albumincarrier
Nifedipinealpha1-acid glycoproteincarrier
NifedipineCytochrome P450 3A5enzyme
AmiodaroneBeta adrenergic receptortarget
AmiodaroneHERG human cardiac K+ channeltarget
AmiodaroneCytochrome P450 2C8enzyme
AmiodaroneCytochrome P450 2C9enzyme
AmiodaroneCytochrome P450 2D6enzyme
AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmiodaroneVoltage gated L-type calcium channeltarget
AmiodaroneCytochrome P450 3A4enzyme
AmiodaroneCytochrome P450 1A2enzyme
AmiodaroneCytochrome P450 1A1enzyme
AmiodaroneP-glycoprotein 1transporter
AmiodaroneCytochrome P450 2C19enzyme
AmiodaroneCytochrome P450 2A6enzyme
AmiodaroneThyroid hormone receptortarget
AmiodaronePeroxisome proliferator-activated receptor gammatarget
AmiodaroneBile salt export pumptransporter
AmiodaroneSolute carrier family 22 member 2transporter
AmiodaroneCytochrome P450 2J2enzyme
AmiodaronePeroxisome proliferator-activated receptor alphatarget
AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
AmiodaroneSerum albumincarrier
DiazoxideATP-sensitive inward rectifier potassium channel 11target
DiazoxideSerum albumincarrier
DiazoxideMitochondrial ATP synthase F1 domaintarget
CarvedilolAlpha-1A adrenergic receptortarget
CarvedilolBeta-1 adrenergic receptortarget
CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
CarvedilolBeta-2 adrenergic receptortarget
CarvedilolVascular endothelial growth factor Atarget
CarvedilolNatriuretic peptides Btarget
CarvedilolGap junction alpha-1 proteintarget
CarvedilolPotassium voltage-gated channel subfamily H member 2target
CarvedilolVascular cell adhesion protein 1target
CarvedilolCytochrome P450 2C9enzyme
CarvedilolCytochrome P450 2D6enzyme
CarvedilolXanthine dehydrogenase/oxidaseenzyme
CarvedilolP-glycoprotein 1transporter
CarvedilolCytochrome P450 1A2enzyme
CarvedilolCytochrome P450 3A4enzyme
CarvedilolCytochrome P450 1A1enzyme
CarvedilolCytochrome P450 2E1enzyme
CarvedilolAlpha-1D adrenergic receptortarget
CarvedilolAlpha-1B adrenergic receptortarget
CarvedilolAlpha-2C adrenergic receptortarget
CarvedilolAlpha-2B adrenergic receptortarget
CarvedilolAlpha-2A adrenergic receptortarget
CarvedilolE-selectintarget
CarvedilolHypoxia-inducible factor 1-alphatarget
CarvedilolInward rectifier potassium channel 4target
CarvedilolUDP-glucuronosyltransferase 1-1enzyme
CarvedilolSerum albumincarrier
CarvedilolUDP-glucuronosyltransferase 2B4enzyme
CarvedilolUDP-glucuronosyltransferase 2B7enzyme
CarvedilolInward rectifier potassium channel 2target
CarvedilolAlpha-1 adrenergic receptorstarget
BretyliumSodium/potassium-transporting ATPase subunit alpha-1target
GuanethidineSodium-dependent noradrenaline transportertarget
PropafenoneSodium channel protein type 5 subunit alphatarget
PropafenonePotassium voltage-gated channel subfamily H member 2target
PropafenoneCytochrome P450 1A2enzyme
PropafenoneCytochrome P450 2D6enzyme
PropafenoneCytochrome P450 3A4enzyme
PropafenoneP-glycoprotein 1transporter
PropafenoneBeta-1 adrenergic receptortarget
PropafenoneBeta-2 adrenergic receptortarget
FlecainideSodium channel protein type 5 subunit alphatarget
FlecainideCytochrome P450 2D6enzyme
FlecainideSodium channel protein type 4 subunit alphatarget
FlecainideCytochrome P450 2C9enzyme
FlecainidePotassium voltage-gated channel subfamily H member 2target
Flecainidealpha1-acid glycoproteincarrier
FlecainideSerum albumincarrier
FlecainideCytochrome P450 1A2enzyme
FlecainideP-glycoprotein 1transporter
FlecainideMultidrug and toxin extrusion protein 1transporter
FlecainideRyanodine receptor 2target
CaptoprilAngiotensin-converting enzymetarget
CaptoprilSerum albumincarrier
Captopril72 kDa type IV collagenasetarget
CaptoprilMatrix metalloproteinase-9target
CaptoprilP-glycoprotein 1transporter
CaptoprilSolute carrier family 15 member 1transporter
CaptoprilSolute carrier family 22 member 6transporter
CaptoprilLeukotriene A-4 hydrolasetarget
CaptoprilB1 bradykinin receptortarget
NadololBeta-1 adrenergic receptortarget
NadololBeta-2 adrenergic receptortarget
NadololP-glycoprotein 1transporter
NadololPOU domain, class 2, transcription factor 1transporter
NadololPOU domain, class 2, transcription factor 2transporter
NadololMultidrug and toxin extrusion protein 1transporter
NadololMultidrug and toxin extrusion protein 2transporter
Nadololalpha1-acid glycoproteincarrier
MetipranololBeta-1 adrenergic receptortarget
MetipranololBeta-2 adrenergic receptortarget
MetipranololCytochrome P450 2D6enzyme
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
EnoxaparinAntithrombin-IIItarget
EnoxaparinCoagulation factor Xtarget
EnoxaparinMyeloperoxidaseenzyme
EnoxaparinProthrombintarget
EpoprostenolP2Y purinoceptor 12target
EpoprostenolProstacyclin receptortarget
EpoprostenolProstacyclin synthasetarget
HydralazineMembrane primary amine oxidasetarget
HydralazineProlyl 4-hydroxylase subunit alpha-1target
HydralazineCytochrome P450 3A4enzyme
HydralazineSerum albumincarrier
HydralazineHypoxia-inducible factor 1-alphatarget
PirbuterolBeta-2 adrenergic receptortarget
PirbuterolBeta-1 adrenergic receptortarget
PractololBeta-1 adrenergic receptortarget
PractololCytochrome P450 2D6enzyme
PolythiazideSolute carrier family 12 member 3target
PolythiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 22 member 8transporter
PolythiazideSerum albumincarrier
QuinethazoneCarbonic anhydrase 1target
QuinethazoneCarbonic anhydrase 2target
QuinethazoneSolute carrier family 12 member 1target
QuinethazoneSolute carrier family 12 member 2target
QuinethazoneSolute carrier family 12 member 3target
CilazaprilAngiotensin-converting enzymetarget
CilazaprilP-glycoprotein 1transporter
CilazaprilSolute carrier family 15 member 1transporter
CilazaprilSolute carrier family 15 member 2transporter
SpiraprilAngiotensin-converting enzymetarget
SpiraprilSolute carrier family 15 member 1transporter
SpiraprilSolute carrier family 15 member 2transporter
EphedrineAlpha-1A adrenergic receptortarget
EphedrineSodium-dependent noradrenaline transportertarget
EphedrineCholinesteraseenzyme
EphedrineSerum albumincarrier
EphedrineBeta-1 adrenergic receptortarget
EphedrineBeta-2 adrenergic receptortarget
EphedrineSynaptic vesicular amine transportertransporter
EphedrineAcetylcholinesteraseenzyme
MephentermineAlpha adrenergic receptortarget
MephentermineBeta adrenergic receptortarget
AmrinoneTumor necrosis factortarget
AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4)target
AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 3target
OxprenololBeta-1 adrenergic receptortarget
OxprenololBeta-2 adrenergic receptortarget
OxprenololSolute carrier family 22 member 2transporter
OxprenololCytochrome P450 2D6enzyme
OxprenololBeta-3 adrenergic receptortarget
Amyl NitriteAtrial natriuretic peptide receptor 1target
Amyl NitriteAldehyde dehydrogenase, mitochondrialenzyme
PargylineAmine oxidase [flavin-containing] Btarget
PargylineAmine oxidase [flavin-containing] Atarget
PiretanideSolute carrier family 12 member 1target
AcetylcholineSolute carrier family 22 member 5transporter
AcetylcholineSolute carrier family 22 member 1transporter
AcetylcholineMuscarinic acetylcholine receptor M1target
AcetylcholineMuscarinic acetylcholine receptor M2target
AcetylcholineMuscarinic acetylcholine receptor M3target
AcetylcholineMuscarinic acetylcholine receptor M4target
AcetylcholineNeuronal acetylcholine receptor subunit alpha-7target
AcetylcholineAcetylcholinesteraseenzyme
AcetylcholineCholinesteraseenzyme
CyclandelateVoltage-dependent calcium channel subunit alpha-2/delta-1target
CyclandelateLiver carboxylesterase 1target
CyclandelateCytochrome P450 3A4enzyme
FlunarizineHistamine H1 receptortarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
FlunarizineCalmodulintarget
FlunarizineCytochrome P450 2D6enzyme
FlunarizineCytochrome P450 2C9enzyme
FlunarizineCytochrome P450 1A1enzyme
FlunarizineCytochrome P450 1A2enzyme
FlunarizineCytochrome P450 2A6enzyme
FlunarizineCytochrome P450 3A4enzyme
NebivololBeta-1 adrenergic receptortarget
NebivololCytochrome P450 2D6enzyme
NebivololBeta-2 adrenergic receptortarget
NebivololCytochrome P450 3A4enzyme
NebivololSerum albumincarrier
NebivololBeta-3 adrenergic receptortarget
NebivololCytochrome P450 2C19enzyme
NylidrinCatechol O-methyltransferaseenzyme
NylidrinVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NylidrinInterferon alpha/beta receptor 2target
NylidrinCytochrome P450 3A4enzyme
Pentaerythritol tetranitrateHemoglobin subunit alphatarget
Pentaerythritol tetranitrateHemoglobin subunit betatarget
Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
Pentaerythritol tetranitrateFree radicalstarget
Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
TolvaptanVasopressin V2 receptortarget
TolvaptanCytochrome P450 3A4enzyme
TolvaptanP-glycoprotein 1transporter
TolvaptanVasopressin V1a receptortarget
XylometazolineAlpha-2A adrenergic receptortarget
XylometazolineAlpha-1A adrenergic receptortarget
XylometazolineAlpha-1B adrenergic receptortarget
XylometazolineAlpha-1D adrenergic receptortarget
XylometazolineAlpha-2B adrenergic receptortarget
XylometazolineAlpha-2C adrenergic receptortarget
LevonordefrinAlpha-2 adrenergic receptorstarget
NaphazolineAlpha-1A adrenergic receptortarget
NaphazolineAlpha-2A adrenergic receptortarget
DrotaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DrotaverineVoltage-dependent L-type calcium channeltarget
PinacidilCytochrome P450 3A4enzyme
TetryzolineAlpha-1 adrenergic receptorstarget
TetryzolineAlpha-2 adrenergic receptorstarget
TinzaparinAntithrombin-IIItarget
TinzaparinA disintegrin and metalloproteinase with thrombospondin motifs 4enzyme
TinzaparinIntegrin alpha-4target
TinzaparinStromal cell-derived factor 1target
TrimetazidineSerum albumincarrier
Trimetazidine3-ketoacyl-CoA thiolase, mitochondrialtarget
IvabradineCytochrome P450 3A4enzyme
IvabradinePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2target
ManidipineVoltage-dependent L-type calcium channeltarget
ManidipineVoltage-dependent T-type calcium channeltarget
ManidipineCytochrome P450 2C9enzyme
ManidipineCytochrome P450 2D6enzyme
ManidipineCytochrome P450 1A1enzyme
ManidipineCytochrome P450 2B6enzyme
ManidipineCytochrome P450 2C19enzyme
ManidipineCytochrome P450 3A4enzyme
ManidipineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
ManidipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
ManidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
IsosorbideGuanylate cyclasetarget
EnalaprilatAngiotensin-converting enzymetarget
EnalaprilatB1 bradykinin receptortarget
DesirudinCarboxypeptidase A1enzyme
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
Protein CCoagulation factor Vtarget
Protein CCoagulation factor VIIItarget
SelexipagProstacyclin receptortarget
SelexipagLiver carboxylesterase 1enzyme
SelexipagCytochrome P450 2C8enzyme
SelexipagCytochrome P450 3A4enzyme
SelexipagSolute carrier organic anion transporter family member 1B1transporter
SelexipagSolute carrier organic anion transporter family member 1B3transporter
SelexipagP-glycoprotein 1transporter
PimobendanCytochrome P450 1A2enzyme
ZofenoprilAngiotensin-converting enzymetarget
LidoflazineCytochrome P450 3A4enzyme
LypressinVasopressin V1a receptortarget
LypressinVasopressin V2 receptortarget
LypressinVasopressin V1b receptortarget
LypressinCanalicular multispecific organic anion transporter 1transporter
Eslicarbazepine acetateCytochrome P450 2C19enzyme
Eslicarbazepine acetateCytochrome P450 3A4enzyme
Eslicarbazepine acetateP2X purinoceptor 4target
Eslicarbazepine acetateUDP-glucuronosyltransferase 1-1enzyme
EslicarbazepineUDP-glucuronosyltransferase 1-1enzyme
EslicarbazepineCytochrome P450 2C19enzyme
EslicarbazepineP2X purinoceptor 4target
EslicarbazepineCytochrome P450 3A4enzyme
Ginkgo bilobaCytochrome P450 2C9enzyme
Ginkgo bilobaPhospholipase A2, membrane associatedtarget
Ginkgo bilobaSodium-dependent noradrenaline transportertarget
Ginkgo bilobaGlycine receptor subunit alpha-1target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit alpha-1target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit beta-2target
Ginkgo bilobaGamma-aminobutyric acid receptor subunit gamma-2target
Ginkgo bilobaCytochrome P450 3A4enzyme
Ginkgo bilobaAmine oxidase [flavin-containing] Atarget
Ginkgo bilobaNitric oxide synthase, inducibletarget
Ginkgo bilobaCytochrome P450 1B1enzyme
Ginkgo bilobaCytochrome P450 1A1enzyme
Ginkgo bilobaCytochrome P450 1A2enzyme
DronedaroneAlpha-1A adrenergic receptortarget
DronedaroneBeta-1 adrenergic receptortarget
DronedaroneAlpha-1B adrenergic receptortarget
DronedaroneAlpha-1D adrenergic receptortarget
DronedaroneAlpha-2A adrenergic receptortarget
DronedaroneAlpha-2B adrenergic receptortarget
DronedaroneAlpha-2C adrenergic receptortarget
DronedaronePotassium voltage-gated channel subfamily H member 2target
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DronedaroneCytochrome P450 2D6enzyme
DronedaroneCytochrome P450 3A4enzyme
DronedaroneP-glycoprotein 1transporter
DronedaronePotassium channel subfamily K member 2target
DronedaroneSerum albumincarrier
DronedaroneSolute carrier family 22 member 2transporter
DronedaroneSolute carrier family 22 member 1transporter
DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DronedaroneSolute carrier family 22 member 8transporter
DronedaroneCytochrome P450 3A5enzyme
DronedaroneCytochrome P450 2J2enzyme
DronedaroneThyroid hormone receptor alphatarget
DronedaroneSodium channel protein type 5 subunit alphatarget
DronedaroneG protein-activated inward rectifier potassium channel 1target
DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DronedaroneInward rectifier potassium channeltarget
DronedaroneSodium/calcium exchanger 1target
DronedaronePotassium voltage-gated channel subfamily D member 3target
RufinamideMetabotropic glutamate receptor 5target
RufinamideLiver carboxylesterase 1enzyme
RufinamideSodium channel protein type 9 subunit alphatarget
RufinamideSerum albumincarrier
RufinamideCytochrome P450 2E1enzyme
RufinamideCytochrome P450 3A4enzyme
LacosamideSodium channel protein type 9 subunit alphatarget
LacosamideSodium channel protein type 3 subunit alphatarget
LacosamideSodium channel protein type 10 subunit alphatarget
LacosamideCytochrome P450 2C19enzyme
LacosamideCytochrome P450 2C9enzyme
LacosamideCytochrome P450 3A4enzyme
PlasminogenTissue-type plasminogen activatorenzyme
PlasminogenUrokinase-type plasminogen activatorenzyme
PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
PerhexilineCytochrome P450 2D6enzyme
PerhexilineCytochrome P450 2B6enzyme
PerhexilineCytochrome P450 3A4enzyme
PerhexilinePotassium voltage-gated channel subfamily H member 2target
StreptokinasePlasminogentarget
StreptokinaseProteinase-activated receptor 1target
StreptokinaseCytosolic phospholipase A2enzyme
FelypressinVasopressin V1a receptortarget
DofetilidePotassium channel subfamily K member 2target
DofetilidePotassium voltage-gated channel subfamily H member 2target
DofetilideATP-sensitive inward rectifier potassium channel 12target
DofetilideCytochrome P450 3A4enzyme
DofetilideSolute carrier family 22 member 2transporter
ReserpineSynaptic vesicular amine transportertarget
ReserpineP-glycoprotein 1transporter
ReserpineSolute carrier family 22 member 1transporter
ReserpineBile salt export pumptransporter
ReserpineCanalicular multispecific organic anion transporter 1transporter
ReserpineSolute carrier family 22 member 2transporter
ReserpineCytochrome P450 3A5enzyme
ReserpineChromaffin granule amine transportertarget
ReserpineBaculoviral IAP repeat-containing protein 5target
ReserpineSolute carrier organic anion transporter family member 1B1transporter
ReserpineSolute carrier organic anion transporter family member 2B1transporter
RemikirenRenintarget
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
IsradipineCytochrome P450 3A4enzyme
IsradipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
IsradipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
IsradipineVoltage-dependent L-type calcium channel subunit beta-2target
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
IsradipineBile salt export pumptransporter
NitroprussideAtrial natriuretic peptide receptor 1target
NitroprussideCytochrome P450 1A1enzyme
MinoxidilATP-sensitive inward rectifier potassium channel 1target
MinoxidilProstaglandin G/H synthase 1target
MinoxidilRenintarget
MinoxidilUDP-glucuronosyltransferase 1-1enzyme
TreprostinilP2Y purinoceptor 12target
TreprostinilPeroxisome proliferator-activated receptor deltatarget
TreprostinilProstacyclin receptortarget
TreprostinilCytochrome P450 2C9enzyme
TreprostinilProstaglandin E2 receptor EP2 subtypetarget
TreprostinilProstaglandin D2 receptortarget
TreprostinilCytochrome P450 2C8enzyme
MexiletineSodium channel protein type 5 subunit alphatarget
MexiletineCytochrome P450 1A2enzyme
MexiletineCytochrome P450 2D6enzyme
MexiletineCytochrome P450 2B6enzyme
MexiletineCytochrome P450 2E1enzyme
MexiletineCytochrome P450 3A4enzyme
MexiletineAryl hydrocarbon receptortarget
DexrazoxaneDNA topoisomerase 2-alphatarget
DexrazoxaneDNA topoisomerase 2-betatarget
PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
PhenylpropanolamineDopamine D1 receptortarget
PhenylpropanolamineBeta-1 adrenergic receptortarget
PhenylpropanolamineBeta-2 adrenergic receptortarget
PhenylpropanolamineAlpha-2 adrenergic receptorstarget
ArdeparinHeparin cofactor 2target
ArdeparinAntithrombin-IIItarget
Sodium tetradecyl sulfateVitamin K-dependent protein Ctarget
Sodium tetradecyl sulfateVitamin K-dependent protein Starget
BosentanEndothelin B receptortarget
BosentanEndothelin-1 receptortarget
BosentanCytochrome P450 3A4enzyme
BosentanCytochrome P450 2C9enzyme
BosentanBile salt export pumptransporter
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
CinnarizineHistamine H1 receptortarget
CinnarizineDopamine D2 receptortarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
CinnarizineCytochrome P450 2D6enzyme
CinnarizineCytochrome P450 2B6enzyme
CinnarizineCytochrome P450 2C9enzyme
CinnarizineCytochrome P450 1A1enzyme
CinnarizineCytochrome P450 1A2enzyme
CinnarizineCytochrome P450 2A6enzyme
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
CinnarizineD(1) dopamine receptortarget
CinnarizineMuscarinic acetylcholine receptortarget
CinnarizineCytochrome P450 3A4enzyme
CinnarizineSerum albumincarrier
FondaparinuxAntithrombin-IIItarget
FondaparinuxCoagulation factor Xtarget
MetaraminolAlpha-1A adrenergic receptortarget
CandoxatrilNeprilysintarget
CandoxatrilAngiotensin-converting enzymetarget
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NicardipineCytochrome P450 3A4enzyme
NicardipineCytochrome P450 2C19enzyme
NicardipineCytochrome P450 2C8enzyme
NicardipineCytochrome P450 2D6enzyme
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
NicardipineAlpha-1A adrenergic receptortarget
NicardipineAlpha-1D adrenergic receptortarget
NicardipineAlpha-1B adrenergic receptortarget
NicardipineMuscarinic acetylcholine receptor M1target
NicardipineMuscarinic acetylcholine receptor M2target
NicardipineMuscarinic acetylcholine receptor M3target
NicardipineMuscarinic acetylcholine receptor M4target
NicardipineMuscarinic acetylcholine receptor M5target
NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NicardipineCalmodulintarget
NicardipineP-glycoprotein 1transporter
NicardipineCytochrome P450 2B6enzyme
NicardipineCytochrome P450 2E1enzyme
NicardipineCytochrome P450 3A5enzyme
NicardipineSolute carrier organic anion transporter family member 1B1transporter
NicardipineBile salt export pumptransporter
NicardipineCytochrome P450 2C9enzyme
NicardipineVoltage-dependent calcium channeltarget
NicardipineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
NicardipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NicardipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
GuanabenzAlpha-2A adrenergic receptortarget
GuanabenzCytochrome P450 1A2enzyme
GuanabenzAlpha-2B adrenergic receptortarget
Magnesium sulfateVoltage-dependent L-type calcium channeltarget
MecamylamineNeuronal acetylcholine receptor subunit alpha-2target
MecamylamineNeuronal acetylcholine receptor subunit alpha-7target
MecamylamineNeuronal acetylcholine receptor subunit alpha-4target
MecamylamineNeuronal acetylcholine receptor subunit beta-2target
MoricizineSodium channel protein type 5 subunit alphatarget
NicergolineAlpha-1A adrenergic receptortarget
NicergolineCytochrome P450 2D6enzyme
MethoxamineAlpha-1A adrenergic receptortarget
MethoxamineAlpha-1B adrenergic receptortarget
MethoxamineAlpha-1D adrenergic receptortarget
EthotoinSodium channel protein type 5 subunit alphatarget
EthotoinNuclear receptor subfamily 1 group I member 2target
EthotoinThyroxine-binding globulincarrier
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilMultidrug resistance-associated protein 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilMultidrug resistance-associated protein 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
Alprostadil15-hydroxyprostaglandin dehydrogenase [NAD(+)]enzyme
AlprostadilSerum albumincarrier
AlprostadilProstaglandin E2 receptor EP3 subtypetarget
AlprostadilProstaglandin E2 receptor EP4 subtypetarget
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
OmapatrilatNeprilysintarget
OmapatrilatAngiotensin-converting enzymetarget
QuinidineSodium channel protein type 5 subunit alphatarget
QuinidineAlpha-1-acid glycoprotein 1carrier
QuinidinePotassium voltage-gated channel subfamily H member 2target
QuinidinePotassium channel subfamily K member 1target
QuinidinePotassium channel subfamily K member 6target
QuinidineCytochrome P450 1A2enzyme
QuinidineCytochrome P450 2E1enzyme
QuinidineCytochrome P450 1A1enzyme
QuinidineCytochrome P450 2D6enzyme
QuinidineCytochrome P450 3A4enzyme
QuinidineCytochrome P450 3A7enzyme
QuinidineSolute carrier family 22 member 2transporter
QuinidineSolute carrier family 22 member 1transporter
QuinidineSolute carrier family 22 member 5transporter
QuinidineP-glycoprotein 1transporter
QuinidineSolute carrier organic anion transporter family member 1A2transporter
QuinidineSolute carrier family 22 member 8transporter
QuinidineCanalicular multispecific organic anion transporter 1transporter
QuinidineSolute carrier family 22 member 4transporter
QuinidineSolute carrier organic anion transporter family member 1B1transporter
QuinidineCytochrome P450 2B6enzyme
QuinidineCytochrome P450 2C9enzyme
QuinidineAlpha-1A adrenergic receptortarget
QuinidineAlpha-1B adrenergic receptortarget
QuinidineAlpha-1D adrenergic receptortarget
QuinidineBile salt export pumptransporter
QuinidineCytochrome P450 2C8enzyme
QuinidineSerum albumincarrier
ZonisamideSodium channel protein type 1 subunit alphatarget
ZonisamideCarbonic anhydrase 1target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
ZonisamideCytochrome P450 3A4enzyme
ZonisamideAldehyde oxidaseenzyme
ZonisamideAmine oxidase [flavin-containing] Btarget
ZonisamideCarbonic anhydrase 2target
ZonisamideCarbonic anhydrase 3target
ZonisamideCarbonic anhydrase 4target
ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
ZonisamideCarbonic anhydrase 6target
ZonisamideCarbonic anhydrase 7target
ZonisamideCarbonic anhydrase-related proteintarget
ZonisamideCarbonic anhydrase 9target
ZonisamideCarbonic anhydrase-related protein 10target
ZonisamideCarbonic anhydrase-related protein 11target
ZonisamideCarbonic anhydrase 12target
ZonisamideCarbonic anhydrase 13target
ZonisamideCarbonic anhydrase 14target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
ZonisamideSodium channel protein type 2 subunit alphatarget
ZonisamideSodium channel protein type 3 subunit alphatarget
ZonisamideSodium channel protein type 4 subunit alphatarget
ZonisamideSodium channel protein type 5 subunit alphatarget
ZonisamideSodium channel protein type 9 subunit alphatarget
ZonisamideSodium channel protein type 11 subunit alphatarget
ZonisamideSodium channel subunit beta-1target
ZonisamideSodium channel subunit beta-2target
ZonisamideSodium channel subunit beta-3target
ZonisamideSodium channel subunit beta-4target
ZonisamideAmine oxidase [flavin-containing] Atarget
ZonisamideCytochrome P450 2C19enzyme
ZonisamideUDP-glucuronosyltransferase 1-1enzyme
ZonisamideCytochrome P450 3A5enzyme
ZonisamideP-glycoprotein 1transporter
ZonisamideGABA(A) Receptor Benzodiazepine Binding Sitetarget
LevosimendanTroponin C, slow skeletal and cardiac musclestarget
LevosimendanATP-sensitive inward rectifier potassium channel 11target
LevosimendanATP-sensitive inward rectifier potassium channel 8target
LevosimendancGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
Naratriptan5-hydroxytryptamine receptor 1Dtarget
Naratriptan5-hydroxytryptamine receptor 1Btarget
Naratriptan5-hydroxytryptamine receptor 1Ftarget
Naratriptan5-hydroxytryptamine receptor 1Atarget
NaratriptanAmine oxidase [flavin-containing] Aenzyme
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
FelodipineCalmodulintarget
FelodipineCytochrome P450 3A4enzyme
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
FelodipineVoltage-dependent L-type calcium channel subunit beta-2target
FelodipineCytochrome P450 2C8enzyme
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
FelodipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
FelodipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FelodipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
FelodipineTroponin C, skeletal muscletarget
FelodipineTroponin C, slow skeletal and cardiac musclestarget
FelodipineMineralocorticoid receptortarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
FelodipineCytochrome P450 3A5enzyme
FelodipineCytochrome P450 3A7enzyme
FelodipineP-glycoprotein 1transporter
FelodipineCytochrome P450 2C9enzyme
FelodipineCytochrome P450 2D6enzyme
FelodipineBile salt export pumptransporter
NitrendipineCytochrome P450 3A4enzyme
NitrendipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-2target
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NitrendipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NitrendipineVoltage-dependent L-type calcium channel subunit beta-2target
NitrendipineCytochrome P450 3A5enzyme
NitrendipineCytochrome P450 3A7enzyme
NitrendipineP-glycoprotein 1transporter
NitrendipineBile salt export pumptransporter
NitrendipineVoltage-dependent L-type calcium channeltarget
NitrendipineCalcium-activated potassium channeltarget
IloprostProstacyclin receptortarget
IloprostTissue-type plasminogen activatortarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IloprostSolute carrier organic anion transporter family member 2B1transporter
IloprostSolute carrier organic anion transporter family member 2A1transporter
IloprostSolute carrier organic anion transporter family member 3A1transporter
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
IloprostProstaglandin E2 receptor EP1 subtypetarget
IloprostProstaglandin D2 receptor 2target
HeparinAntithrombin-IIItarget
HeparinCoagulation factor Xtarget
HeparinP-selectintarget
HeparinHeparanaseenzyme
HeparinFibroblast growth factor receptor 4target
HeparinFibroblast growth factor 4target
HeparinFibroblast growth factor 19target
HeparinFibroblast growth factor receptor 1target
HeparinFibroblast growth factor 1target
HeparinFibroblast growth factor receptor 2target
HeparinFibroblast growth factor 2target
HeparinPlatelet factor 4target
HeparinHepatocyte growth factortarget
PapaverinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
PapaverinecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
PapaverinePhosphodiesterase enzymestarget
TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
TrimethaphanCholinesteraseenzyme
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
AcebutololBeta-1 adrenergic receptortarget
AcebutololCytochrome P450 2D6enzyme
AcebutololBeta-2 adrenergic receptortarget
AcebutololP-glycoprotein 1transporter
EncainideSodium channel protein type 5 subunit alphatarget
EncainideCytochrome P450 2D6enzyme
BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
BepridilSodium/potassium-transporting ATPase subunit alpha-1target
BepridilPotassium voltage-gated channel subfamily KQT member 1target
BepridilTroponin C, slow skeletal and cardiac musclestarget
BepridilCalmodulintarget
BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
BepridilP-glycoprotein 1transporter
BepridilCytochrome P450 2D6enzyme
BepridilPotassium voltage-gated channel subfamily H member 2target
BepridilCytochrome P450 3A4enzyme
FosphenytoinSodium channel protein type 5 subunit alphatarget
FosphenytoinCytochrome P450 2C19enzyme
FosphenytoinCytochrome P450 2B6enzyme
FosphenytoinCytochrome P450 2C9enzyme
FosphenytoinCytochrome P450 3A4enzyme
FosphenytoinSerum albumincarrier
FosphenytoinCytochrome P450 1A2enzyme
FosphenytoinUDP-glucuronosyltransferase 1-6enzyme
FosphenytoinUDP-glucuronosyltransferase 1-9enzyme
FosphenytoinThyroxine-binding globulincarrier
SaprisartanType-1 angiotensin II receptortarget
PenbutololAlpha-1-acid glycoprotein 1carrier
PenbutololBeta-1 adrenergic receptortarget
PenbutololBeta-2 adrenergic receptortarget
Penbutolol5-hydroxytryptamine receptor 1Atarget
Penbutolol5-hydroxytryptamine receptor 1Btarget
PenbutololCytochrome P450 2D6enzyme
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-1target
MibefradilCytochrome P450 3A4enzyme
MibefradilCytochrome P450 1A2enzyme
MibefradilCytochrome P450 2D6enzyme
MibefradilCytochrome P450 3A5enzyme
MibefradilCytochrome P450 3A7enzyme
MibefradilP-glycoprotein 1transporter
MibefradilVoltage-dependent T-type calcium channel subunit alpha-1Itarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Starget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
MibefradilVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
MibefradilVoltage-dependent L-type calcium channel subunit beta-2target
MibefradilVoltage-dependent L-type calcium channel subunit beta-3target
MibefradilVoltage-dependent L-type calcium channel subunit beta-4target
MibefradilCytochrome P450 11B1, mitochondrialenzyme
MibefradilCytochrome P450 11B2, mitochondrialenzyme
DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DigitoxinSerum albumincarrier
DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DigitoxinCytochrome P450 3A4enzyme
DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DigitoxinP-glycoprotein 1transporter
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
AjmalineAlpha-1-acid glycoprotein 1carrier
AjmalineSodium channel protein type 5 subunit alphatarget
AprindineAlpha-1-acid glycoprotein 1carrier
AprindineCalmodulintarget
AprindineSodium channel protein type 5 subunit alphatarget
AprindineCytochrome P450 2D6enzyme
Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
EpicaptoprilAngiotensin-converting enzymetarget
EpicaptoprilFEZ-1 proteintarget
EpicaptoprilCarbapenem-hydrolyzing beta-lactamase BlaB-1target
EpicaptoprilMetallo-beta-lactamase L1target
EpicaptoprilBeta-lactamasetarget
EpicaptoprilOrganic hydroperoxide resistance protein, putativetarget
S-EthylisothioureaNitric oxide synthase oxygenasetarget
S-EthylisothioureaNitric oxide synthase, inducibletarget
S-EthylisothioureaNitric oxide synthase, endothelialtarget
Platelet Activating FactorGanglioside GM2 activatortarget
Platelet Activating FactorP-glycoprotein 1transporter
Platelet Activating FactorPlatelet-activating factor receptortarget
ColforsinP-glycoprotein 1transporter
ColforsinAdenylate cyclase type 2target
ColforsinGuanine nucleotide-binding protein G(s) subunit alpha isoforms shorttarget
ColforsinAdenylate cyclase type 5target
ColforsinCystic fibrosis transmembrane conductance regulatortarget
ColforsinAdenylate cyclasetarget
ColforsinCalcium-activated potassium channeltarget
ColforsinCREB-binding proteintarget
ColforsinExtracellular signal-regulated kinase (ERK)target
ColforsinMucin-2target
ColforsinPlasminogen activator inhibitor 1target
TerlipressinVasopressin V1a receptortarget
TerlipressinVasopressin V2 receptortarget
TerlipressinVasopressin V1b receptortarget
Calyculin ASerine/threonine-protein phosphatase PP1-gamma catalytic subunittarget
PhenolThermolysintarget
PhenolSerum albumintarget
Erythritol5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferasetarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideCalmodulintarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin C, slow skeletal and cardiac musclestarget
N-(6-Aminohexyl)-5-Chloro-1-NaphthalenesulfonamideTroponin I, cardiac muscletarget
PrenylamineCalmodulintarget
PrenylamineMyosin light chain kinase 2, skeletal/cardiac muscletarget
PrenylamineCytochrome P450 3A4enzyme
Tienilic acidCytochrome P450 2C9enzyme
DebrisoquineSodium-dependent noradrenaline transportertarget
DebrisoquineCytochrome P450 2D6enzyme
DebrisoquineP-glycoprotein 1transporter
DebrisoquineCytochrome P450 1A1enzyme
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
EnoximonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
NesiritideAtrial natriuretic peptide receptor 1target
NesiritideAtrial natriuretic peptide receptor 2target
NesiritideAtrial natriuretic peptide receptor 3target
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
ClevidipineCytochrome P450 2C9enzyme
ClevidipineCytochrome P450 2D6enzyme
ClevidipineCytochrome P450 2E1enzyme
ClevidipineCytochrome P450 2C19enzyme
ClevidipineCytochrome P450 3A4enzyme
ClevidipineCholinesteraseenzyme
DesmoteplasePlasminogentarget
DefibrotideAdenosine receptor A1target
DefibrotideAdenosine receptor A2atarget
DefibrotideAdenosine receptor A2btarget
LofexidineAlpha-2A adrenergic receptortarget
LofexidineAlpha-1A adrenergic receptortarget
Lofexidine5-hydroxytryptamine receptor 1Atarget
Lofexidine5-hydroxytryptamine receptor 7target
Lofexidine5-hydroxytryptamine receptor 2Ctarget
Lofexidine5-hydroxytryptamine receptor 1Dtarget
LofexidineCytochrome P450 2D6enzyme
LofexidineCytochrome P450 1A2enzyme
LofexidineCytochrome P450 2C19enzyme
LofexidineATP-binding cassette sub-family B member 5transporter
LofexidineMultidrug and toxin extrusion protein 1transporter
AzimilidePotassium voltage-gated channel subfamily E member 1target
AzimilidePotassium voltage-gated channel subfamily KQT member 1target
AzimilidePotassium voltage-gated channel subfamily H member 2target
AzimilideCytochrome P450 1A1enzyme
AzimilideCytochrome P450 3A4enzyme
AzimilideCytochrome P450 3A5enzyme
AzimilideCytochrome P450 2D6enzyme
AncrodFibrinogen alpha chaintarget
BeraprostProstacyclin receptortarget
BeraprostCytochrome P450 2C8enzyme
TetrodotoxinSodium channel protein type 1 subunit alphatarget
TetrodotoxinSodium channel protein type 2 subunit alphatarget
TetrodotoxinSodium channel protein type 3 subunit alphatarget
TetrodotoxinSodium channel protein type 8 subunit alphatarget
FibrinolysinPlasminogen activator inhibitor 1target
FibrinolysinUrokinase-type plasminogen activatortarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IbudilastcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
CanertinibEpidermal growth factor receptortarget
SulodexideHeparin cofactor 2target
SulodexideAntithrombin-IIItarget
AR-9281Bifunctional epoxide hydrolase 2target
AmbrisentanEndothelin B receptortarget
AmbrisentanEndothelin-1 receptortarget
AmbrisentanCytochrome P450 2C19enzyme
AmbrisentanCytochrome P450 3A4enzyme
AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
AmbrisentanP-glycoprotein 1transporter
AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
AmbrisentanCytochrome P450 3A5enzyme
DexanabinolTumor necrosis factortarget
Dotarizine5-hydroxytryptamine receptor 2Atarget
Dotarizine5-hydroxytryptamine receptor 1Atarget
DotarizineVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
Dotarizine5-hydroxytryptamine receptor 2Ctarget
DotarizineCytochrome P450 3A4enzyme
CariporideSodium/hydrogen exchanger 1target
CariporideMyeloperoxidaseenzyme
TezosentanEndothelin-1 receptortarget
TezosentanEndothelin B receptortarget
DalfampridineCytochrome P450 2E1enzyme
DalfampridinePotassium voltage-gated channel subfamily D member 2target
DalfampridinePotassium voltage-gated channel subfamily D member 3target
DalfampridinePotassium voltage-gated channel subfamily A member 1target
DalfampridinePotassium voltage-gated channel subfamily A member 4target
DalfampridinePotassium voltage-gated channel subfamily A member 2target
DalfampridinePotassium voltage-gated channel subfamily A member 3target
DalfampridinePotassium voltage-gated channel subfamily A member 5target
DalfampridinePotassium voltage-gated channel subfamily A member 6target
DalfampridinePotassium voltage-gated channel subfamily A member 7target
DalfampridinePotassium voltage-gated channel subfamily A member 10target
DalfampridinePotassium voltage-gated channel subfamily B member 1target
DalfampridinePotassium voltage-gated channel subfamily B member 2target
DalfampridinePotassium voltage-gated channel subfamily C member 1target
DalfampridinePotassium voltage-gated channel subfamily C member 2target
DalfampridinePotassium voltage-gated channel subfamily C member 3target
DalfampridinePotassium voltage-gated channel subfamily D member 1target
DalfampridineSolute carrier family 22 member 2transporter
Ethanolamine oleateCalcium ionstarget
Ethanolamine oleateCoagulation factor XIItarget
NilvadipineCytochrome P450 3A4enzyme
NilvadipineCytochrome P450 2A6enzyme
NilvadipineCytochrome P450 2C19enzyme
NilvadipineCytochrome P450 2C8enzyme
NilvadipineCytochrome P450 2E1enzyme
NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
NilvadipineVoltage-dependent L-type calcium channel subunit beta-2target
NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NilvadipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
NilvadipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
NilvadipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
NilvadipineVoltage gated L-type calcium channeltarget
NilvadipineVoltage-dependent T-type calcium channeltarget
SparteineCytochrome P450 2D6enzyme
DanaparoidAntithrombin-IIItarget
DalteparinVascular endothelial growth factor Atarget
DalteparinHeparanaseenzyme
DalteparinAntithrombin-IIItarget
DalteparinP-selectintarget
TranilastHematopoietic prostaglandin D synthasetarget
TranilastCytochrome P450 3A4enzyme
TranilastCytochrome P450 2C9enzyme
Ferulic acidEndo-1,4-beta-xylanase Ytarget
Ferulic acidEndo-1,4-beta-xylanase Ztarget
Ferulic acidEst1etarget
Ferulic acidO-methyltransferasetarget
Ferulic acidMonocarboxylate transporter 1transporter
Ferulic acidMonocarboxylate transporter 4transporter
FasudilcAMP-dependent protein kinase inhibitor alphatarget
FasudilcAMP-dependent protein kinase catalytic subunit alphatarget
FasudilRho-associated protein kinase 1target
FasudilRho-associated protein kinase 2target
Y-27632cAMP-dependent protein kinase catalytic subunit alphatarget
Y-27632cAMP-dependent protein kinase inhibitor alphatarget
Y-27632Rho-associated protein kinase 1target
Y-27632Rho-associated protein kinase 2target
BupranololBeta-1 adrenergic receptortarget
BupranololBeta-2 adrenergic receptortarget
BupranololBeta-3 adrenergic receptortarget
BupranololCytochrome P450 2D6enzyme
NadroparinProto-oncogene c-Fostarget
NadroparinMyc proto-oncogene proteintarget
NadroparinP-selectintarget
NadroparinAntithrombin-IIItarget
TemocaprilSolute carrier family 15 member 1transporter
TemocaprilSolute carrier organic anion transporter family member 1A2transporter
TemocaprilAngiotensin-converting enzymetarget
TetraethylammoniumSolute carrier family 22 member 1transporter
TetraethylammoniumSolute carrier family 22 member 2transporter
TetraethylammoniumSolute carrier family 22 member 3transporter
TetraethylammoniumSolute carrier family 22 member 4transporter
TetraethylammoniumSolute carrier family 22 member 5transporter
TetraethylammoniumSolute carrier family 22 member 8transporter
TetraethylammoniumpH-gated potassium channel KcsAtarget
TetraethylammoniumNeuronal acetylcholine receptor subunit alpha-9target
TetraethylammoniumCalcium-activated potassium channel subunit alpha-1target
TetraethylammoniumPotassium voltage-gated channel subfamily A member 1target
TetraethylammoniumMultidrug and toxin extrusion protein 1transporter
Inositol nicotinateSodium-coupled monocarboxylate transporter 1transporter
Inositol nicotinateATP synthase subunit beta, mitochondrialenzyme
Inositol nicotinateHydroxycarboxylic acid receptor 3target
Inositol nicotinateHydroxycarboxylic acid receptor 2target
Inositol nicotinateDiacylglycerol O-acyltransferase 2enzyme
IndoraminAlpha-1A adrenergic receptortarget
IndenololCytochrome P450 2D6enzyme
IfenprodilGlutamate receptor ionotropic, NMDA 1target
IfenprodilGlutamate receptor ionotropic, NMDA 2Btarget
IfenprodilG protein-activated inward rectifier potassium channel 1target
IfenprodilG protein-activated inward rectifier potassium channel 2target
IfenprodilG protein-activated inward rectifier potassium channel 4target
HexamethoniumNeuronal acetylcholine receptor subunit alpha-2target
FendilineCytochrome P450 3A4enzyme
EperisoneCytochrome P450 3A4enzyme
TiboloneEstrogen receptor alphatarget
TiboloneSteryl-sulfataseenzyme
Tibolone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1enzyme
Tibolone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
TiboloneSulfotransferase 1A1enzyme
TiboloneSerum albumincarrier
PinaveriumVoltage-dependent L-type calcium channel subunit alpha-1Starget
PinaveriumCytochrome P450 3A4enzyme
Xanthinol60S ribosomal protein L3target
XanthinolNAD(P) transhydrogenase, mitochondrialtarget
XanthinolGlyceraldehyde-3-phosphate dehydrogenasetarget
XanthinolIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
Xanthinol2-oxoglutarate dehydrogenase, mitochondrialtarget
XanthinolMalate dehydrogenase, mitochondrialtarget
CirazolineAlpha-1A adrenergic receptortarget
CirazolineAlpha-1B adrenergic receptortarget
CirazolineAlpha-1D adrenergic receptortarget
CirazolineAlpha-2 adrenergic receptorstarget
SynephrineAlpha-1 adrenergic receptorstarget
MoxisylyteCholinesteraseenzyme
MoxisylyteCytochrome P450 3A Subfamilyenzyme
MoxisylyteAlpha adrenergic receptortarget
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
NicorandilATP-binding cassette sub-family C member 9target
BarnidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
BarnidipineCytochrome P450 3A4enzyme
BarnidipineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
BarnidipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
BenidipineVoltage-dependent L-type calcium channeltarget
BenidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
BenidipineVoltage-dependent T-type calcium channeltarget
BenidipineCytochrome P450 3A4enzyme
BenidipineCytochrome P450 3A5enzyme
CilnidipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
CilnidipineVoltage-dependent L-type calcium channeltarget
CilnidipineCytochrome P450 3A4enzyme
DarodipineCytochrome P450 3A4enzyme
EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EfonidipineCytochrome P450 3A4enzyme
EfonidipineVoltage gated L-type calcium channeltarget
EfonidipineVoltage-dependent calcium channeltarget
EfonidipineVoltage-dependent T-type calcium channeltarget
EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
LacidipineCytochrome P450 3A4enzyme
LacidipineSerum albumincarrier
LacidipineAlpha-1-acid glycoprotein 1carrier
LacidipineVoltage-dependent L-type calcium channeltarget
NiguldipineAlpha-1A adrenergic receptortarget
NiguldipineCytochrome P450 3A4enzyme
NiguldipineP-glycoprotein 1transporter
NiludipineCytochrome P450 3A4enzyme
MoxonidineNischarintarget
MoxonidineAlpha-2A adrenergic receptortarget
MolsidomineGuanylate cyclase soluble subunit alpha-2target
MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
TrapidilPlatelet-derived growth factor receptor betatarget
TrapidilCyclic nucleotide phosphodiesterasetarget
RilmenidineAlpha-2A adrenergic receptortarget
TalinololCytochrome P450 2D6enzyme
TalinololP-glycoprotein 1transporter
TalinololCanalicular multispecific organic anion transporter 1transporter
AnisodamineCytochrome P450 2D6enzyme
Angiotensin IIType-1 angiotensin II receptortarget
CarboxyamidotriazoleCytochrome P450 3A4enzyme
NaftopidilCytochrome P450 3A4enzyme
TetrahydropalmatineDopamine D1 receptortarget
TetrahydropalmatineDopamine D2 receptortarget
TetrahydropalmatineCytochrome P450 3A4enzyme
VinpocetineCytochrome P450 3A4enzyme
Sarpogrelate5-hydroxytryptamine receptor 2Ctarget
Sarpogrelate5-hydroxytryptamine receptor 2Atarget
Eplivanserin5-hydroxytryptamine receptor 2Atarget
Eplivanserin5-hydroxytryptamine receptor 2Ctarget
LandiololCytochrome P450 2D6enzyme
NitroaspirinProstaglandin G/H synthase 1target
Ketanserin5-hydroxytryptamine receptor 2Atarget
PilsicainideBile salt export pumptransporter
BucindololCytochrome P450 2D6enzyme
GallopamilCytochrome P450 3A4enzyme
GallopamilP-glycoprotein 1transporter
DihydralazineCytochrome P450 1A2enzyme
PhosphocreatineGuanidinoacetate N-methyltransferasetarget
PhosphocreatineSodium- and chloride-dependent creatine transporter 1target
PhosphocreatineCreatine kinase M-typetarget
PhosphocreatineCreatine kinase U-type, mitochondrialtarget
PhosphocreatineCreatine kinase S-type, mitochondrialtarget
PhosphocreatineCreatine kinase B-typetarget
BamifyllineCytochrome P450 1A2enzyme
DihydroergocristineSerotonin Receptorstarget
DihydroergocristineBeta adrenergic receptortarget
DihydroergocristineAlpha adrenergic receptortarget
DihydroergocristineDopamine receptortarget
DihydroergocristineBile salt export pumptransporter
DihydroergocristineCytochrome P450 3A4enzyme
DihydroergocryptineCytochrome P450 3A4enzyme
BencyclaneCytochrome P450 3A4enzyme
OtiloniumCytochrome P450 3A4enzyme
CloranololCytochrome P450 2D6enzyme
TerodilineCytochrome P450 3A4enzyme
EpanololCytochrome P450 2D6enzyme
TertatololCytochrome P450 2D6enzyme
BufyllineCytochrome P450 1A2enzyme
CaroverineCytochrome P450 3A4enzyme
CandesartanType-1 angiotensin II receptortarget
CandesartanCytochrome P450 2C8enzyme
CandesartanCytochrome P450 2C9enzyme
CandesartanP-glycoprotein 1transporter
CandesartanUDP-glucuronosyltransferase 1-3enzyme
CandesartanProstaglandin G/H synthase 1enzyme
CandesartanSolute carrier organic anion transporter family member 1B1transporter
WIN 55212-2Cytochrome P450 3A4enzyme
DexverapamilP-glycoprotein 1target
DexverapamilCytochrome P450 3A4enzyme
DexverapamilP-glycoprotein 1transporter
EmopamilP-glycoprotein 1target
EmopamilCytochrome P450 3A4enzyme
EmopamilP-glycoprotein 1transporter
LomerizineP-glycoprotein 1target
LomerizineCytochrome P450 3A4enzyme
LomerizineP-glycoprotein 1transporter
TetrandrineP-glycoprotein 1target
TetrandrineCytochrome P450 3A4enzyme
TetrandrineP-glycoprotein 1transporter
CilazaprilatAngiotensin-converting enzymetarget