Oligopeptides
- Name
- Oligopeptides
- Accession Number
- DBCAT000051
- Description
Peptides composed of between two and twelve amino acids.
- Drugs
Drug Drug Description Leuprolide A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty. Goserelin A synthetic analog of luteinizing hormone-releasing hormone used to treat breast cancer and prostate cancer by reducing secretion of gonadotropins from the pituitary. Desmopressin A synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia. Cetrorelix A synthetic peptide antagonist of gonadotropin releasing hormone used to prevent luteinizing hormone surges in women undergoing assisted reproduction therapy. Vasopressin A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. Glutathione For nutritional supplementation, also for treating dietary shortage or imbalance Pentagastrin A gastrin-like molecule used as a diagnostic aid for the evaluation of gastric acid secretory function, gastric hypersecretion, and Zollinger-Ellison tumors. Ceruletide Caerulein is used in the treatment of paralytic ileus and as diagnostic aid in pancreatic malfunction. Enalapril A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. Gonadorelin A synthetic GnRH used to test the function of gonadotropes and the pituitary. Nafarelin A gonadotropin releasing hormone agonist used to treat central precocious puberty. Lisinopril An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. Spirapril Spirapril is an ACE inhibitor class drug used to treat hypertension. Buserelin A LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. Ganirelix A GnRH antagonist used in assisted reproduction in women undergoing controlled ovarian hyperstimulation to control ovulation by inhibiting the premature LH surges. Histrelin A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer. Triptorelin A GnRH agonist indicated for the palliative treatment of advanced prostate cancer. Protirelin A synthetic analogue of thyrotropin-releasing hormone that has been used during diagnostic tests to evaluate function of the thyroid gland. Enalaprilat An antihypertensive agent used for the management of hypertension when oral therapy is not practical. Deslorelin Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones. Angiotensin II A peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock. Lypressin Not Annotated Glutathione disulfide An ingredient of ophthalmic irrigation solutions used during ophthalmological procedures. Antipain Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells... Ornithine An amino acid commonly found as a component in total parenteral nutrition. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Angiotensin 1-7 TXA127 has been investigated for the treatment of Miscellaneous Peripheral Blood Cell Abnormalities. Bradykinin Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2. Aclerastide Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic. Angiotensinamide Not Annotated Felypressin For use as an alternative to adrenaline as a localising agent, provided that local ischaemia is not essential. Aspartame Used as a diet supplement and sugar substitute. Ilomastat Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor. N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine Not Available S-(2,4-dinitrophenyl)glutathione Not Available Terlipressin A drug used to treat bleeding caused by esophageal varices. JE-2147 Not Available N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline Not Available S-octylglutathione Not Available Glutathionylspermidine Not Available Enalkiren Not Available gamma-Glutamylcysteine Not Available Trypanothione Not Available Z-Pro-Prolinal Not Available S-benzylglutathione Not Available S-(4-nitrobenzyl)glutathione Not Available S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione Not Available S-Hexylglutathione Not Available S-Methyl glutathione Not Available Olcegepant For the treatment of migraine headaches. Canfosfamide Intended for the treatment of various forms of cancer. NOV-002 Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer. Ezatiostat Investigated for use/treatment in myelodysplastic syndrome. Golotimod Investigated for use/treatment in hepatitis (viral, C), infectious and parasitic disease (unspecified), and tuberculosis. VX-765 Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders. Flovagatran Investigated for use/treatment in thrombosis. Oglufanide Investigated for use/treatment in hepatitis (viral, C). Sar9, Met (O2)11-Substance P Investigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection. Darinaparsin Investigated for use/treatment in blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), solid tumors, multiple myeloma, and liver cancer. Talabostat Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), lung cancer, melanoma, and pancreatic cancer. Icatibant A bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE). Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Labradimil Investigated for use/treatment in brain cancer and pediatric indications. Saralasin Not Annotated acetylleucyl-leucyl-norleucinal Not Available Kelatorphan Not Available Brentuximab vedotin A CD30-directed antibody-drug conjugate used to treat various types of lymphoma. Polaprezinc Peptic ulcer disease, dyspepsia . Carnosine Carnosine has been investigated for the treatment of Gulf War Illness. Birinapant Birinapant has been investigated for the treatment of Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML). Danegaptide Danegaptide has been investigated for the treatment of Focus of Study is STEMI. Alanyl glutamine A dipeptide consisting of alanine and glutamine used for supplementation. Ibodutant Ibodutant has been used in trials studying the treatment of Irritable Bowel Syndrome and Irritable Bowel Syndrome With Diarrhea. Elobixibat Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. Selepressin Selepressin has been used in trials studying the treatment of Septic Shock. Zoptarelin doxorubicin Zoptarelin doxorubicin has been used in trials studying the treatment of Breast Cancer, Ovarian Cancer, Prostate Cancer, Endometrial Cancer, and Urothelial Carcinoma, among others. CMX-2043 CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention. Neladenoson bialanate Neladenoson bialanate has been investigated for the treatment of Heart Failure. Arginine glutamate Two amino acids indicated in the treatment of hyperammonemia and in combination for total parenteral nutrition. Ornipressin Not Annotated Aspartyl-alanyl-diketopiperazine Aspartyl-alanyl-diketopiperazine is under investigation in clinical trial NCT03349645 (An Open Label Extension Study to Assess the Safety of Long-Term Treatment With Ampion for Severe OA of the Knee). VM4-037 VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037). Glycylglutamine An ingredient in amino acid solutions for parenteral nutrition. Glycyltyrosine An ingredient in amino acid solutions for parenteral nutrition. Leupeptin Not Annotated CA-074 methyl ester CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239] S-Nitrosoglutathione Not Annotated - Drugs & Drug Targets