Antiviral Agents
- Name
- Antiviral Agents
- Accession Number
- DBCAT000066 (DBCAT001226, DBCAT003779)
- Description
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
- ATC Classification
- Drugs
Drug Drug Description Vidarabine An antiviral agent used to treat various viral infections. Idoxuridine A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. Docosanol An antiviral used to treat orofacial herpes sores. Fomivirsen Indicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428]. Edoxudine A deoxythymidine analog used to treat herpetic keratitis. Trifluridine A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers. Acyclovir A guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. Sinecatechins A topical agent used to treat external genital and perianal warts in immunocompetent adult patients. Inosine pranobex A medication used to treat subacute sclerosing panencephalitis. Tromantadine Tromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex. Ganciclovir A DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. Peginterferon alfa-2a A modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. Interferon alfa-n1 A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus. Peginterferon alfa-2b A purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers. Interferon beta-1a A form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis. Interferon alfacon-1 A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections. Enfuvirtide An HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals. Palivizumab A monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients. Oseltamivir A neuraminidase inhibitor used in the prophylaxis and treatment of influenza. Nelfinavir A viral protease inhibitor used in the treatment of HIV infection. Indinavir A protease inhibitor used to treat HIV infection. Nevirapine A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. Penciclovir A topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. Tenofovir disoproxil A nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection. Cidofovir An antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. Famciclovir A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster. Entecavir A nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases. Rimantadine An RNA synthesis inhibitor used to prevent influenza A infection. Zidovudine A dideoxynucleoside used in the treatment of HIV infection. Ritonavir An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. Foscarnet An antiviral used to treat CMV, HIV, and HSV infections. Zanamivir A neuraminidase inhibitor used to treat influenza A and B. Valaciclovir An guanine nucleoside antiviral used to treat herpes exacerbations. Efavirenz A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. Stavudine A dideoxynucleoside used in the treatment of HIV infection. Amprenavir A protease inhibitor used to treat HIV infection. Delavirdine A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. Lamivudine A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. Adefovir dipivoxil A nucleotide analog used to treat chronic hepatitis B. Ribavirin A guanosine nucleoside used to treat some forms of Hepatitis C. Emtricitabine A nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. Didanosine A reverse transcriptase inhibitor used to treat HIV. Amantadine A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. Tipranavir A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. Zalcitabine A dideoxynucleoside used to treat HIV. Abacavir An antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. Saquinavir An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Telbivudine A thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). Fosamprenavir An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. Lopinavir An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. Valganciclovir An antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). Maraviroc A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. Calanolide A For use in combination treatment of HIV infection (AIDS). Pleconaril Investigated for use/treatment in upper respiratory infection. Interferon alfa An immunomodulator used to treat hepatitis B and C as well as certain types of cancer including cutaneous T-cell lymphoma and renal cell carcinoma. Leronlimab A humanized monoclonal antibody being investigated Alovudine Investigated for use/treatment in HIV infection. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Etravirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. Peramivir An intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days. Clevudine Investigated for use/treatment in hepatitis (viral, B). Raltegravir An antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. Rilpivirine A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). Dolutegravir An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. Sofosbuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Ledipasvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Paritaprevir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. Tenofovir alafenamide A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease. Cenicriviroc Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex. Pritelivir Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. Sorivudine Sorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections. Vedroprevir Vedroprevir has been investigated for the treatment of Hepatitis C, Chronic. Beclabuvir Beclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic. Atevirdine Atevirdine has been used in trials studying the treatment of HIV Infections. Lobucavir Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. Racivir Racivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine and its positive enantiomer. Racivir has... Fiacitabine Fiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections. Moroxydine Not Annotated Metisazone Not Annotated Adefovir Not Annotated Podofilox A topical agent used for the treatment of external genital warts and perianal warts. Ibacitabine Not Annotated Tenofovir A nucleotide analog indicated in the treatment of HIV infections. Tecovirimat An antiviral medication used to treat smallpox, monkeypox, and cowpox. Vesatolimod Vesatolimod has been used in trials studying the treatment of Hepatitis B and Chronic Hepatitis B. Asunaprevir An NS3 protease inhibitor used to treat hepatitis C genotype 1b. Telaprevir An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. Maribavir A cytomegalovirus (CMV) pUL97 kinase inhibitor used for the treatment of refractory post-transplant CMV infection. Boceprevir A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. Elvitegravir An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Daclatasvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. Faldaprevir Faldaprevir has been investigated for the treatment of Chronic Hepatitis C. Umifenovir A dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses. Letermovir An antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease. Baloxavir marboxil A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. Oseltamivir acid Not Available Brivudine A drug used to treat herpes zoster. Emivirine Emivirine has been used in trials studying the treatment of HIV Infections. Lapachone Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell. Betulinic Acid Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. Elbasvir An antiviral and NS5A inhibitor used to treat hepatitis C infections. Grazoprevir An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. Velpatasvir A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. Bictegravir An integrase inhibitor used to treat HIV infections. Voxilaprevir A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. Doravirine A non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. Ibalizumab A CD4-specific antibody used to treat HIV infections. Pibrentasvir A Hepatitis C NS5A inhibitor used to treat Hepatitis C. Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. Alovudine F-18 Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography). Fialuridine Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU). Rupintrivir Investigated for use/treatment in viral infection. BMS-488043 Investigated for use/treatment in HIV infection. UC-781 Investigated for use/treatment in HIV infection. Elvucitabine Investigated for use/treatment in hepatitis (viral, B) and HIV infection. Taribavirin Investigated for use/treatment in hepatitis (viral, C). Artesunate Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. Ruzasvir Ruzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection. Laninamivir octanoate Laninamivir octanoate has been used in trials studying the treatment of Asthma. Ingavirin Ingavirin has been used in trials studying the treatment of Influenza and Common Cold. Dexelvucitabine Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus. Laninamivir Laninamivir has been used in trials studying the treatment of Influenza. Odalasvir Odalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection. Adafosbuvir Adafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335). Uprifosbuvir Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and... Radavirsen Radavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza). JE-2147 Not Available N-hydroxyguanidine Not Available 5'-Guanylylmethylenebisphosphonate Not Available JPC-3210 JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant Plasmodium falciparum lines, low cytotoxicity, potent in vivo efficacy against murine... Pirodavir Pirodavir is an antipicornavirus agent. R-82913 Not Available Opaviraline Not Available L-756423 Not Available Remdesivir A nucleoside analog used to treat RNA virus infections including COVID-19. TMC-310911 TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections.... Triazavirin An antiviral used to treat several strains of influenza. Valomaciclovir Investigated for use/treatment in herpes zoster infections and viral infection. Valomaciclovir stearate Valomaciclovir stearate is under investigation in clinical trial NCT00831103 (A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster). Ravidasvir Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection). Islatravir Islatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)). Baloxavir Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)). GS-441524 An experimental nucleoside analog antiviral investigated for its use in the treatment of Ebola and SARS-CoV-2 infections. Amenamevir Amenamevir has been used in trials studying the treatment of Herpes Zoster, Herpes Simplex, Herpes Genitalis, and Safety of Amenamevir. Favipiravir An antiviral used to manage influenza, and that has the potential to target other viral infections. Cabotegravir An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection. Troclosene Not Annotated Oxymatrine Oxymatrine is under investigation in clinical trial NCT02202473 (Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects). Rintatolimod Not Annotated Cilgavimab An extended half-life recombinant monoclonal IgG1κ antibody directed against the SARS-CoV-2 S protein for COVID-19 prophylaxis in individuals unable to undergo COVID-19 immunization. Tixagevimab An extended half-life recombinant monoclonal IgG1κ antibody directed against the SARS-CoV-2 S protein for COVID-19 prophylaxis in individuals unable to undergo COVID-19 immunization. Galidesivir Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various... Brincidofovir An oral lipid prodrug of cidofovir used in the treatment of human smallpox disease. Netivudine Netivudine has been used in trials studying the treatment of Chickenpox and HIV Infections. Ribavirin monophosphate Not Annotated Tenofovir exalidex Tenofovir exalidex is under investigation in clinical trial NCT01080820 (A Safety, Tolerability and Pharmacokinetic Study of a Single Dose of CMX157 in Healthy Volunteers). Molnupiravir An orally bioavailable isopropylester cytidine analog used to treat COVID-19. Pradefovir mesylate Investigated for use as a prodrug for Hepsera in treating hepatitis (viral, B). Pradefovir Pradefovir is a prodrug of adefovir. Interferon alfa-2a A form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses. Interferon alfa-2b A form of recombinant human interferon used to treat hepatitis B and C infection, genital warts, hairy cell leukemia, follicular lymphoma, malignant melanoma, and AIDs-related Kaposi's sarcoma. 2'-fluoro-5-ethylarabinosyluracil 2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma,... Remestemcel-L Indicated for in the management of acute Graft versus Host Disease (aGvHD) in pediatric patients. Acute GvHD should be refractory to treatment with systemic corticosteroid therapy and/or other immunosuppressive agents.... Ziresovir Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)). Gimsilumab Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects). Anti-SARS-CoV-2 REGN-COV2 Anti-SARS-COV-2 REGN-COV2 is a combination of novel antibodies designed by Regeneron for both the prevention and treatment of SARS-COV-2, the virus that causes COVID-19. This drug is a combination of... Bamlanivimab A neutralizing human IgG1κ monoclonal antibody against the SARS-CoV-2 spike (S) protein for use in patients aged 12 and over at high risk of developing severe COVID-19. AZD7442 AZD7442 is a combination of SARS-CoV-2 antibodies (AZD8895 + AZD1061) currently undergoing phase I clinical trials for the prevention and treatment of COVID-19. It was developed by AstraZeneca with the... Atoltivimab Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells. Maftivimab Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells. Odesivimab Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells. Gontivimab Gontivimab is under investigation in clinical trial NCT03468829 (Efficacy and Safety of ALX-0171 in Adult Hematopoietic Stem Cell Transplant (HSCT) Recipients Who Present With Respiratory Syncytial Virus (RSV) Infection). Ansuvimab A fully human monoclonal IgG1 antibody directed against the GP1,2 surface protein of Zaire ebolavirus that is an effective treatment for Ebola virus disease. Astegolimab Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia). Zansecimab Zansecimab is under investigation in clinical trial NCT04342897 (A Study of LY3127804 in Participants With COVID-19). Avdoralimab Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection). Meplazumab Meplazumab is a humanized anti-CD147 antibody being investigated as an add-on therapy in patients with COVID-19 pneumonia. Aplaviroc Investigated for use/treatment in HIV infection. Capravirine Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. Dapivirine Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures. Fostemsavir An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. PF-232798 PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects). Rovafovir etalafenamide Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen). Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Tipranavir C-14 Tipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects). BMS-955176 BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults). Viral Macrophage-Inflammatory Protein Viral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer... HIV Integrase Inhibitor HIV Integrase Inhibitor is under investigation in clinical trial NCT00397566 (A Multiple Ascending Dose Study of BMS-707035 in HIV-1 Infected Subjects). Nirmatrelvir An oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19. Azodicarbonamide Not Annotated Lenacapavir A first-in-class capsid inhibitor being investigated for use in HIV-1 treatment. Bulevirtide A drug for the treatment of chronic Hepatitis D infection in adults with compensated liver disease. Coblopasvir Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C). Interferon tau Not Annotated Modified vaccinia ankara A live, non-replicating orthopoxvirus vaccine used to prevent smallpox, monkeypox, and other diseases caused by vaccinia virus. Sotrovimab A monoclonal antibody for the treatment of mild-to-moderate COVID-19 in patients at increased risk for death or hospitalization. Carbovir Not Annotated Ajoene Not Annotated Pocapavir Not Annotated HPA-23 HPA-23 is an investigational antiviral compound. Ammonium trichlorotellurate Ammonium trichlorotellurate is an investigational compound with anti-tumour and anti-inflammatory properties. Aphidicolin Aphidicolin is an antimitotic and antiviral metabolite of the mould Cephalosporium aphidicola. It inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162] Dideoxyadenosine Not Annotated Tilorone Not Annotated Interferon alfa-1b Not Annotated - Drugs & Drug Targets